scholarly journals Progenitor Stem Cells Behavior in the Adrenal Gland of Acute-Stress Albino Rat Model: A Histological and Immunohistochemical Study

2020 ◽  
Vol 12 (2) ◽  
pp. 77-89
Author(s):  
Nermeen Lashine ◽  
Amany Shams ◽  
Shaima Almasry ◽  
Huda El-Tahry ◽  
Marwa Abd El-kader
Keyword(s):  
Stem Cells ◽  
Adrenal Gland ◽  
Rat Model ◽  
Acute Stress ◽  
Immunohistochemical Study ◽  
Albino Rat

scholarly journals Histological and immunohistochemical study on the role of mesenchymal stem cells in the repair of experimentally induced skin burn in adult male albino rat

QJM ◽  
2018 ◽  
Vol 111 (suppl_1) ◽  
Author(s):  
D Ahmed Yousef Yehia ◽  
N Mohamed El Shakaa ◽  
M Abd Elrahman Ahmed ◽  
G Abd El Khalek Ibrahim
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Adult Male ◽  
Immunohistochemical Study ◽  
Skin Burn ◽  
Albino Rat ◽  
Experimentally Induced

The Safety and Efficacy of Mupirocin Topical Spray for Burn Wound Healing in A Rat Model

2019 ◽  
Vol 10 (01) ◽  
Author(s):  
Sritharadol Rutthapol ◽  
Chunhachaichana Charisopon ◽  
Kumlungmak Sukanjana ◽  
Buatong Wilaiporn ◽  
Dechraksa Janwit ◽  
...  
Keyword(s):  
Wound Healing ◽  
Matrix Metalloproteinase ◽  
Rat Model ◽  
Transforming Growth Factor ◽  
Immunohistochemical Study ◽  
Enzyme Linked Immunosorbent Assay ◽  
Burn Wound ◽  
Safety And Efficacy ◽  
Burn Wound Healing ◽  
Tgf Β1

ABSTRACT This study evaluated the effect of mupirocin topical spray on burn wound healing in a rat model. Fifteen male Sprague Dawley rats were used to create full-thickness burns on the rat dorsum using a cylindrical stainless steel rod. The rats were topically treated with normal saline solution (NSS), mupirocin spray, ointment, and solution. The wound size and morphological evaluation were investigated by photographs and clinical criterions for wound healing. The histology was observed by hematoxylin and eosin (HandE) staining assay. The immunohistochemical study was evaluated by detection of transforming growth factor-beta 1 (TGF-β1), and the ratio of matrix metalloproteinase-9 to the tissue inhibitor of matrix metalloproteinase-1 (MMP-9/TIMP-1) was quantified using the enzyme-linked immunosorbent assay (ELISA) assay. A complete healing was observed at 28 days in all treatments. Mupirocin formulations accelerated the wound healing faster than NSS in size. However, the clinical criteria indicated a desirable skin appearance in the mupirocin spray and ointment treated groups. The histological evaluations showed no differences between the treatments while the immunohistochemical study revealed that all treatments reduced the level of TGF-β1 over time, particularly on day 28 in the mupirocin spray and ointment treated groups. The MMP-9/TIMP-1 ratio was significantly lower in the mupirocin spray and ointment treated groups than in the NSS and mupirocin solution groups. This study shows the safety and efficacy in the use of mupirocin topical spray. The topical mupirocin spray is an alternative suitable for development as a human topical anti-infective and wound protection spray.

Adipose tissue-derived stem cells versus bone marrow-derived stem cells as an angiogenic therapy after ischemic limb injury in the adult male albino rat

2018 ◽  
Vol 41 (1) ◽  
pp. 172-191
Author(s):  
Mohamed Mohamed ◽  
Mona Ali ◽  
Maha Abo-gazia ◽  
Rania Galhom ◽  
Amira farage
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Adipose Tissue ◽  
Adult Male ◽  
Albino Rat ◽  
Angiogenic Therapy ◽  
Ischemic Limb ◽  
Limb Injury

Mesenchymal Stem Cells Enhanced Cardiac Nerve Sprouting via Nerve Growth Factor in a Rat Model of Myocardial Infarction

2014 ◽  
Vol 20 (12) ◽  
pp. 2023-2029 ◽  
Author(s):  
Jian Chen ◽  
Shaoxin Zheng ◽  
Hui Huang ◽  
Suihua Huang ◽  
Changqing Zhou ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Nerve Growth Factor ◽  
Growth Factor ◽  
Rat Model ◽  
Nerve Growth ◽  
Cardiac Nerve ◽  
Nerve Sprouting

scholarly journals Human Dental Pulp Stem Cells (DPSCs) Therapy in Rescuing Photoreceptors and Establishing a Sodium Iodate-Induced Retinal Degeneration Rat Model

2021 ◽  
Author(s):  
Chenshen Lam ◽  
Hiba Amer Alsaeedi ◽  
Avin Ee-Hwan Koh ◽  
Mohd Hairul Nizam Harun ◽  
Angela Ng Min Hwei ◽  
...  
Keyword(s):  
Stem Cells ◽  
Retinal Degeneration ◽  
Rat Model ◽  
Dental Pulp ◽  
Dental Pulp Stem Cells ◽  
Sodium Iodate ◽  
Human Dental Pulp
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