scholarly journals Urinary Transforming Growth Factor Beta-1 in Children With Nephrotics Syndrome and End-Stage Renal Disease

GEGET ◽  
2002 ◽  
Vol 2 (1) ◽  
pp. 19-27
Author(s):  
Farida Farid ◽  
Ihab El-Hakim ◽  
Mona Osman ◽  
Sekina Ghaleb
1998 ◽  
Vol 53 (3) ◽  
pp. 639-644 ◽  
Author(s):  
Manikkam Suthanthiran ◽  
Ashwani Khanna ◽  
David Cukran ◽  
Rohini Adhikarla ◽  
Vijay K. Sharma ◽  
...  

2000 ◽  
Vol 36 (5) ◽  
pp. 945-952 ◽  
Author(s):  
Lorenzo S. Malatino ◽  
Francesca Mallamaci ◽  
Francesco A. Benedetto ◽  
Ignazio Bellanuova ◽  
Alessandro Cataliotti ◽  
...  

2000 ◽  
Vol 6 (S2) ◽  
pp. 612-613
Author(s):  
S. Ren ◽  
C. Wei

Transforming growth factor-beta (TGF-β) is a growth-regulating peptide that has been shown to enhance collagen production both in vivo and in vitro. The previous studies demonstrated that TGF-β 1 is present in the normal animal myocardium. However, the expression and localization of TGF-β 1 and TGF-P receptor in human myocardium remain unclear. Therefore, the present study was designed to determine the TGF-β 1 and its receptor in human myocardium in normal subjects and in patients with end-stage congestive heart failure (CHF).Human ventricular tissues were obtained from five normal subjects and five patients with end-stage CHF during cardiac transplantation. TGF-β 1 and TGF-beta type I receptor (TGF-βRI) were determined by immunohistochemical staining (IHCS). The results of IHCS was evaluated by staining density scores (0, no staining; 1, minimal staining; 2, mild staining; 3, moderate staining; and 4, strong staining). The positive staining area (+%) in entire section was also determined.


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