Beneficial Effects of the Mediterranean Diet on Metabolic Syndrome

Obesity and metabolic syndrome (MetS) are worldwide major health challenges. The Mediterranean diet (MD) is associated with a better cardiometabolic profile, but these beneficial effects may be influenced by genetic variations, modulating the predisposition to obesity or MetS. The aim was to assess whether interaction effects occur between an obesity genetic risk score (obesity-GRS) and the MD on adiposity and MetS in European adolescents. Multiple linear regression models were used to assess the interaction effects of an obesity-GRS and the MD on adiposity and MetS and its components. Interaction effects between the MD on adiposity and MetS were observed in both sex groups (p < 0.05). However, those interaction effects were only expressed in a certain number of adolescents, when a limited number of risk alleles were present. Regarding adiposity, a total of 51.1% males and 98.7% females had lower body mass index (BMI) as a result of higher MD adherence. Concerning MetS, only 9.9% of males with higher MD adherence had lower MetS scores. However, the same effect was observed in 95.2% of females. In conclusion, obesity-related genotypes could modulate the relationship between MD adherence and adiposity and MetS in European adolescents; the interaction effect was higher in females than in males.

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Mediterranean diet and metabolic syndrome: the evidence

Public Health Nutrition ◽

10.1017/s1368980009990449 ◽

2009 ◽

Vol 12 (9A) ◽

pp. 1607-1617 ◽

Cited By ~ 105

Author(s):

Nancy Babio ◽

Mònica Bulló ◽

Jordi Salas-Salvadó

Keyword(s):

Metabolic Syndrome ◽

Mediterranean Diet ◽

Fruits And Vegetables ◽

Disease Risk ◽

Cardiovascular Disease Risk ◽

Atherogenic Dyslipidemia ◽

Favourable Effect ◽

Processed Meat ◽

Beneficial Effects ◽

The Mediterranean

AbstractBackgroundThe Mediterranean diet has long been related to a lower cardiovascular disease risk; however, more recent evidences also indicate that it has a favourable effect on adiposity and type 2 diabetes.DesignReview of the available literature in relation to Mediterranean diet and metabolic syndrome.ResultsSeveral components of Mediterranean diet patterns have been inversely related with body mass index. They are considered to be modulators of insulin resistance, can exert beneficial effects on blood pressure, improve atherogenic dyslipidemia or attenuate the inflammatory burden associated with metabolic syndrome. Furthermore, a lower prevalence of metabolic syndrome has been associated with dietary patterns rich in fruits and vegetables, nuts, olive oil, legumes and fish, moderate in alcohol and low in red meat, processed meat, refined carbohydrates and whole-fat dairy products.ConclusionsThere is much evidence suggesting that the Mediterranean diet could serve as an anti-inflammatory dietary pattern, which could help to fight diseases related to chronic inflammation, including metabolic syndrome.

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Special Issue “Mediterranean Diet and Metabolic Diseases”

Nutrients ◽

10.3390/nu13082680 ◽

2021 ◽

Vol 13 (8) ◽

pp. 2680

Author(s):

Emmanuella Magriplis ◽

Michail Chourdakis

Keyword(s):

Mediterranean Diet ◽

Dietary Patterns ◽

Metabolic Diseases ◽

Special Issue ◽

Beneficial Effects ◽

The Mediterranean

The Mediterranean diet (MD) has been considered among the healthiest dietary patterns since a little over 50 years ago, Ancel Keys—as the key figure—provided evidence for the beneficial effects of the MD [...]

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The Central European diet as an alternative to the Mediterranean diet in atherosclerosis prevention in postmenopausal obese women with a high risk of metabolic syndrome - a randomized nutrition-al trial [pdf]

Acta Scientiarum Polonorum Technologia Alimentaria ◽

10.17306/j.afs.2018.0593 ◽

2018 ◽

Vol 17 (4) ◽

pp. 399-407 ◽

Cited By ~ 1

Author(s):

Monika Duś-Żuchowska ◽

◽

Joanna Bajerska ◽

Patrycja Krzyżanowska ◽

Agata Chmurzyńska ◽

...

Keyword(s):

Metabolic Syndrome ◽

High Risk ◽

Mediterranean Diet ◽

Obese Women ◽

Central European ◽

The Mediterranean ◽

Atherosclerosis Prevention

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The Central European diet as an alternative to the Mediterranean diet in atherosclerosis prevention in postmenopausal obese women with a high risk of metabolic syndrome - a randomized nutrition-al trial

Acta Scientiarum Polonorum Technologia Alimentaria ◽

10.17306/j.afs.0593 ◽

2018 ◽

Vol 17 (4) ◽

pp. 399-407 ◽

Cited By ~ 1

Author(s):

Monika Duś-Żuchowska ◽

◽

Joanna Bajerska ◽

Patrycja Krzyżanowska ◽

Agata Chmurzyńska ◽

...

Keyword(s):

Metabolic Syndrome ◽

High Risk ◽

Mediterranean Diet ◽

Obese Women ◽

Central European ◽

The Mediterranean ◽

Atherosclerosis Prevention

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Efficacy of Cognitive Behavioral Therapy in Adherence to the Mediterranean Diet in Metabolic Syndrome Patients: A Randomized Controlled Trial

Journal of Nutrition Education and Behavior ◽

10.1016/j.jneb.2018.06.003 ◽

2018 ◽

Vol 50 (9) ◽

pp. 896-904 ◽

Cited By ~ 2

Author(s):

Jaqueline Garcia-Silva ◽

Nuria N. Navarrete ◽

María Isabel Peralta-Ramírez ◽

Antonio García-Sánchez ◽

Miguel Ángel Ferrer-González ◽

...

Keyword(s):

Metabolic Syndrome ◽

Randomized Controlled Trial ◽

Cognitive Behavioral Therapy ◽

Mediterranean Diet ◽

Behavioral Therapy ◽

Controlled Trial ◽

Cognitive Behavioral ◽

Randomized Controlled ◽

The Mediterranean

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If we eat soy, do we keep the beneficial effects of the Mediterranean diet?

Nutrition & Food Science ◽

10.1108/nfs-10-2019-0322 ◽

2020 ◽

Vol 50 (6) ◽

pp. 1099-1108

Author(s):

Giovanni Aulisa ◽

Claudio Binda ◽

Elvira Padua ◽

Antonio Pratesi ◽

Alfonso Bellia ◽

...

Keyword(s):

Literature Review ◽

Mediterranean Diet ◽

Design Methodology ◽

Point Of View ◽

Positive Health ◽

Content Type ◽

Beneficial Effects ◽

Typical Food ◽

The Mediterranean ◽

Practical Implications

Purpose This study aims to evaluate if soya consumption can compromise or positively influence the effects of the Mediterranean diet (MD). Design/methodology/approach A full literature review has been conducted as part of a proposal of a new point of view on the consumption of soya and its derivatives in areas where until a few decades ago this type of food did not exist at all. Findings There does not seem to be any contraindications for soy systematic use, therefore, excluding historical-geographical reasons, soya could be included in an MD without altering the benefits associated with it. Practical implications Soya is not advised as a typical food in the MD, but promoting its use could probably contribute to increase the variety of the diet and likely consolidates the positive health benefits characteristic of MD. Originality/value To the best of the authors’ knowledge, this review is one of the first to evaluate soybean consumption within the MD.

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