scholarly journals Why Not to Use the Handgrip Test in the Assessment of Cardiovascular Autonomic Neuropathy Among Patients with Diabetes Mellitus?

2016 ◽  
Vol 15 (1) ◽  
pp. 66-73 ◽  
Author(s):  
Anna Körei ◽  
Miklós Kempler ◽  
Ildikó Istenes ◽  
Orsolya Vági ◽  
Zsuzsanna Putz ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Autonomic Neuropathy ◽  
Cardiovascular Autonomic Neuropathy ◽  
Patients With Diabetes ◽  
Handgrip Test

scholarly journals Cardiovascular Autonomic Neuropathy in Patients with Diabetes in Cotonou, Benin: A Cross-Sectional Study

2021 ◽  
Vol 5 (5) ◽  
pp. 01-05
Author(s):  
Gninkoun Comlan Jules ◽  
Fanou Joseph Soglo ◽  
Alassani Adebayo Sabi Cossi ◽  
Djrolo François
Keyword(s):  
Diabetes Mellitus ◽  
Blood Pressure ◽  
Risk Factor ◽  
Autonomic Neuropathy ◽  
Cross Sectional Study ◽  
Cardiovascular Autonomic Neuropathy ◽  
Sectional Study ◽  
Cross Sectional ◽  
Cardiovascular Morbidity And Mortality ◽  
Patients With Diabetes

Background Diabetes mellitus is well known as a major risk factor for cardiovascular diseases. Cardiovascular autonomic neuropathy is one of the diabetes complications that has a major impact on cardiovascular morbidity and mortality in patients with diabetes. Aim : To determine the prevalence of cardiovascular autonomic neuropathy in patients with diabetes attending the diabetic center in Cotonou and to identify its risk factors. Materials and Methods : It was a cross-sectional study. Cardiovascular autonomic neuropathy was identified using deep breathing test, standind test and the blood pressure response to standing test (orthostatic hypotension). Chi square test was used for statistical analysis and différence was considered significant when p<0.05. Results : A total of 405 subjects were included in the study. Their mean age was 53.67±11,68 years and the mean diabetes duration was 6.66 years. The prevalence of cardiovascular autonomic neuropathy was 65.9%. Regarding the severity of the complication in neuropathic patients, 51.7% of them had an early neuropathy, 41.2% have presented a moderate neuropathy and 7.1% have presented a severe neuropathy. Factors associated with cardiovascular autonomic neuropathy were age of patients (p = 0.0002), diabetes duration (p = 0.0012), hypertension (p =0.0015), dyslipidemia (p = 0.027) and high pulsed blood pressure (p = 0.032) Conclusion : Cardiovascular autonomic neuropathy is a very frequent complication of diabetes mellitus. Unfortunately this complication of diabetes is not often explored in the patient's follow-up examination. As this complication is recognised to be associated with high cardiovascular morbidity and mortality, systematic screening can be recommanded in patients with long duration of diabetes or presenting an other cardiovascular risk factor.

scholarly journals Correlations between hormone levels and cardiovascular autonomic neuropathy in menopausal patients with diabetes mellitus

2020 ◽  
Vol 36 (6) ◽  
Author(s):  
Guiling Zhang ◽  
Wei Wei ◽  
Bo Tan ◽  
Jingqin Liu
Keyword(s):  
Diabetes Mellitus ◽  
Autonomic Neuropathy ◽  
Glycosylated Hemoglobin ◽  
Fasting Blood Glucose ◽  
Cardiovascular Autonomic Neuropathy ◽  
Hormone Levels ◽  
Female Patients ◽  
Patients With Diabetes ◽  
Hs Crp ◽  
Stimulating Hormone

Objective: To discuss the correlation between hormone levels and cardiovascular autonomic neuropathy (CAN) in menopausal patients with Type-2 diabetes mellitus (T2DM). Methods: This clinical research study was conducted at Department of Endocrinology, Baoding No. 1 Hospital from January 2016 to December 2017. In this study a total of 386 menopausal female patients with T2DM were selected and classified into two groups according to the CAN function test: the CAN group (80 cases) and the DM group (306 cases). The Kupperman score (KI integral) was calculated for all participants in the study, and the following indexes were measured: body mass index (BMI), blood estrogen (E2), follicle-stimulating hormone (FSH), luteinizing hormone (LH), thyroid-stimulating hormone (TSH), free thyroxine (FT4), free triiodothyronine (FT3), fasting blood-glucose (FBG), glycosylated hemoglobin (HbA1c), serum lipids, uric acid (SUA), hypersensitive c-reactive protein (CRP), etc. Results: The FBG, HbA1c, TGs, Hs-CRP, SUA, KI score, TSH, FSH and LH of the CAN group were obviously higher than the same parameters in the DM group (P﹤0.01, P﹤0.05), while HDL-C, E2, FT3 and FT4 were significantly lower (P﹤0.01, P﹤0.05). Pearson correlation analysis indicated that CAN presents a positive correlation with HbA1c, TGs, hs-CRP and SUA and a negative correlation with HDL-C and E2, and the difference was statistically significant (P<0.05). The multifactor logistic regression analysis results showed that HbA1c (OR=3.980, 95%CI=1.268~10.319) and E2 (OR=3.075, 95%CI=1.167~7.366) are independent risk factors for CAN. Conclusion: The CAN morbidity of menopausal female patients with T2DM is high, and HbA1c and E2 should be mainly monitored to identify and treat CAN early. doi: https://doi.org/10.12669/pjms.36.6.2088 How to cite this:Zhang G, Wei W, Tan B, Liu J. Correlations between hormone levels and cardiovascular autonomic neuropathy in menopausal patients with diabetes mellitus. Pak J Med Sci. 2020;36(6):---------. doi: https://doi.org/10.12669/pjms.36.6.2088 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

scholarly journals UPDATE OF CARDIOVASCULAR AUTONOMIC NEUROPATHY IN PATIENTS WITH DIABETES

2021 ◽  
Vol 68 (2) ◽  
pp. 162-168
Author(s):  
Andra-Elena Nica ◽  
◽  
Carmen Dobjansch ◽  
Oana Andreea Parlițeanu ◽  
Emilia Rusu ◽  
...  
Keyword(s):  
Autonomic Neuropathy ◽  
Cardiovascular Autonomic Neuropathy ◽  
Interval Prolongation ◽  
Prognostic Role ◽  
Qt Interval Prolongation ◽  
Cardiovascular Reflex ◽  
Cardiovascular Reflex Tests ◽  
Patients With Diabetes ◽  
Symptoms And Signs ◽  
Reverse Dipping

The burden of diabetic cardiovascular autonomic neuropathy (CAN) is expected to increase due to the diabetes epidemic and its early and widespread appearance. CAN has a definite prognostic role for mortality and cardiovascular morbidity. Putative mechanisms for this are tachycardia, QT interval prolongation, orthostatic hypotension, reverse dipping, and impaired heart rate variability, while emerging mechanisms like inflammation support the pervasiveness of autonomic dysfunction. Efforts to overcome CAN under-diagnosis are: by promoting screening for symptoms and signs; by simplifying cardiovascular reflex tests.

Diabetes mellitus in anaesthesia

2012 ◽  
Vol 12 (2) ◽  
pp. 60-64 ◽  
Author(s):  
Jadelis Giquel ◽  
Yiliam F Rodriguez-Blanco ◽  
Christina Matadial ◽  
Keith Candiotti
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Immune Deficiency ◽  
Autonomic Neuropathy ◽  
Endocrine System ◽  
Morbidity And Mortality ◽  
Cardiovascular Autonomic Neuropathy ◽  
Operative Morbidity ◽  
Endocrine Diseases ◽  
Collagen Tissue

Anaesthesiologists frequently encounter patients with diseases of the endocrine system, in particular diabetes mellitus. The major risk factors for people with diabetes undergoing surgery are the associated end-organ diseases: cardiovascular autonomic neuropathy, joint collagen tissue, and immune deficiency. Due to the fact that endocrine diseases can be associated with significant peri-operative morbidity and mortality, it is critical that anaesthesiologists understand these disorders and when indicated request the appropriate investigations.

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