scholarly journals Tinnitus: A Tingling Mystery to be Decrypted

2020 ◽  
Vol 13 (1) ◽  
pp. 37-50
Author(s):  
Ruban Nersisson ◽  
Arjun Sengupta ◽  
Swapnil Sarkar ◽  
Sushant Agrawal ◽  
Pushpreet Singh ◽  
...  

Tinnitus is a hearing disorder that causes ringing, buzzing or hissing sensation to the patient’s auditory senses. It has become a very common complaint over the years affecting around 7-8% of the human population all over the world. The disorder causes the patients to feel irritable, annoyed, depressed, and distressed. As a result, it obstructs their sense of relaxation, enjoyment, and even their sleep - thus forcing them to avoid any social gatherings. There has been a substantial amount of work that has been carried out pertinent to this disorder. This paper reviews existing research and work done regarding Tinnitus effects, causes, and diagnosis. The numerous ways in which Tinnitus could affect an individual have been depicted. From the plethora of probable causes of this disorder, the most conceivable ones are highlighted. Moreover, this paper documents and reviews the attempts at treating Tinnitus, relevant engineering breakthroughs, and the various ways in which Tinnitus noise is suppressed – such as Tinnitus Retraining Therapy, Neuromodulation, and Signal processing approach. The manuscripts highlight the pros and cons of these methods. Over 45 research articles and other reliable internet medical sources were reviewed and these pieces of work were contrasted. These findings should help in understanding both – the disorder, as well as the situation of the patients suffering from it. Through this manuscript, an attempt was made to spread awareness about the mysterious disorder.

2002 ◽  
Vol 13 (10) ◽  
pp. 559-581 ◽  
Author(s):  
James A. Henry ◽  
Martin A. Schechter ◽  
Stephen M. Nagler ◽  
Stephen A. Fausti

Two methods for treating tinnitus are compared. Tinnitus masking has been used for over 25 years, and although this method is used in clinics around the world, there are many misconceptions regarding the proper protocol for its clinical application. Tinnitus retraining therapy has been used clinically for over 12 years and has received considerable international attention. Although these methods are distinctive in their basic approach to tinnitus management, certain aspects of treatment appear similar. These aspects of treatment have created considerable confusion and controversy, especially regarding the use of "sound therapy" as a basic component of treatment. It is the objective of this article to clarify the major differences that exist between these two forms of treatment.


2008 ◽  
Vol 128 (4) ◽  
pp. 365-368 ◽  
Author(s):  
Akio Hatanaka ◽  
Yousuke Ariizumi ◽  
Ken Kitamura

2020 ◽  
Vol 17 (4) ◽  
pp. 337-354 ◽  
Author(s):  
Rameen Butt ◽  
Hammad Siddiqui ◽  
Raheel Ahmed Soomro ◽  
Muhammad Mujtaba Asad

Purpose This era is the time for upskilling and producing workforce that is capable of effectively dealing with the day-by-day increasing demand of the industry. As the world is changing, its needs are changing in the same way and at the same speed. The world has become more digitized now. Moreover, we have a dramatic shift from Education 1.0 to Education 4.0 these days. The world now is practicing the internet of things, cloud storage, cyber-physical system and artificial intelligence. The purpose of this study is to identify the factors that affect the level of motivation toward the integration and implication of Industrial Revolution (IR) 4.0 in the education system of Pakistan by considering the Government policies. Design/methodology/approach For analyzing these factors, 150 research articles were sought out, out of which 84 were chosen for reviewing purpose based on the authentication of and relevance to this study by considering the Pakistani context. All the research articles have been selected from reputed indexed journals from databases (Scopus and Web of Science). Findings The findings of this review suggest that many factors affect the motivation toward integration and implementation of IR 4.0. These factors mainly include human factors, intrinsic values and influencing factors. Moreover, there is no such framework that provides the base to Education 4.0 in Pakistan because the things exist but are not systematic. Educators are motivated, but there are no resources; policies are there, but there is no practice or implementation. Pakistan is lacking in the latest trends related to Education 4.0 and even has no experience because people are used to doing things manually, but technology is the need of this era. Furthermore, the findings of this study will be useful for developing a systematic plan or a framework of the integration and implication of IR 4.0 that ultimately gives rise to Education 4.0 in the education system of Pakistan. Originality/value To the authors’ knowledge, no other study has been conducted on this topic in Pakistan. Also, there is a very little work done on this topic anywhere else in the world. The world is still exploring the IR 4.0, and our topic is solemnly related to these resolutions. Thus, there is a very little amount of literature related to this study.


Author(s):  
Pawel J. Jastreboff ◽  
Jonathan W. P. Hazell

2020 ◽  
Vol 26 ◽  
Author(s):  
Sridevi Vaadala ◽  
Naveen Ponneri ◽  
Venkat Shashank Karnam ◽  
Ramachandra Reddy Pamuru ◽  
Mohammed Arifullah

Background: Phytoestrogens are non-endocrine, non-steroidal secondary derivatives of plants and consumed through plant-based diet also named as “dietary estrogens”. The major sources of phytoestrogens are soy and soy-based foods, flax seed, chickpeas, green beans, dairy products, etc. The dietary inclusion of phytoestrogen based foods play a crucial role in the maintenance of metabolic syndrome cluster including obesity, diabetes, blood pressure, cancer, inflammation, cardiovascular diseases, postmenopausal ailments and their complications. In recent days, phytoestrogens are the preferred molecules for hormone replacement therapy. On the other hand, they act as endocrine disruptors via estrogen receptor mediated pathways. These effects are not restricted to adult males or females and identified even in development. Objective: Since phytoestrogenic occurrence is high at daily meal for most people from all over the world, they focused to study for its beneficiary effects towards developing pharmaceutical drugs for treating various metabolic disorders by keeping an eye on endocrine disruption. Conclusion: The present review emphasizes the pros and cons of phytoestrogens on human health, which may help to direct the pharmaceutical industry to produce various phytoestrongen based drugs against various metabolic disorders.


Author(s):  
Masoud Keighobadi ◽  
Maryam Nakhaei ◽  
Ali Sharifpour ◽  
Ali Akbar Khasseh ◽  
Sepideh Safanavaei ◽  
...  

Background: This study was designed to analyze the global research on Lophomonas spp. using bibliometric techniques. Methods: A bibliometric research was carried out using the Scopus database. The analysis unit was the research articles conducted on Lophomonas spp. Results: Totally, 56 articles about Lophomonas spp. were indexed in the Scopus throughout 1933-2019 ( 87 years ) with the following information: (A) The first article was published in 1933; (B) 21 different countries contributed in studies related to Lophomonas spp.; (C) China ranked first with 16 publications about Lophomonas spp.; and (D) “Brugerolle, G” and “Beams, H.W.” from France and the US participated in 4 articles respectively, as the highest number of publications in the Lophomonas spp. network. Discussion: After 87 years, Lophomonas still remains unknown for many researchers and physicians around the world. Further studies with high quality and international collaboration are urgently needed to determine different epidemiological aspects and the real burden of the mysterious parasite worldwide.


Medicina ◽  
2021 ◽  
Vol 57 (5) ◽  
pp. 438
Author(s):  
Jagadish Hosmani ◽  
Shazia Mushtaq ◽  
Shahabe Saquib Abullais ◽  
Hussain Mohammed Almubarak ◽  
Khalil Assiri ◽  
...  

Background and Objectives: Oral cancer is the 6th most common cancer in the world and oral leukoplakia is an oral potentially malignant disorder that could develop into oral cancer. This systematic review focusses on randomized clinical trials for recombinant adenovirus p-53 (rAD-p53) therapy for the treatment of oral leukoplakia and cancer. Materials and Methods: We searched for research articles on various databases such as Pubmed/Medline, Embase, CNKI (China National Knowledge Infra-structure), Springerlink, cochrane and Web of sciences from 2003 to 2020. MeSH (Medical Subject Headings) terms were used for the search. Inclusion criteria included original research, randomized clinical trials and articles only in English language. Exclusion criteria were any articles that were not research articles, not randomized trials, non-human studies, etc. The articles were further graded on the Jadad scale. Results: 578 articles were assessed from various databases; only 3 articles were found to be appropriate for this review. Thus, meta-analysis was not performed because of heterogeneity and lack of data. In the three studies, whether rAD-p53 was used as a standalone therapy or with other therapies, there was a beneficial effect of the therapy. Furthermore, there were no serious adverse events and the only adverse events reported were fever, pain at the local injection site, flu-like symptoms and lowered WBC count. Conclusions: Thus, we can conclude that this therapy has a potential for beneficial therapeutic effects and further clinical trials with more patients need to be performed to get better understanding of the effect of rAD-p53 therapy, which probably will pave the way to its approval in other parts of the world.


2021 ◽  
pp. 251512742199252
Author(s):  
Robert A. Boyle ◽  
Jerome A. Katz ◽  
Patricia G. Bagsby

For entrepreneurs, being offered a distribution deal by Walmart seems like a dream come true. After all, what better way to have a new product quickly appear in thousands of stores all around the United States or maybe even all around the world? This dream became a reality for Marty, the creator of Tiny Sips—a simple, wholesome children’s beverage made from Montana spring water and all-natural ingredients. As the details and conditions related to the distribution deal became apparent, however, Marty soon understood that doing business at that level requires sophisticated entrepreneurial savvy and a great deal of capital. The joy of possibly selling Tiny Sips everywhere suddenly became eclipsed by questions about how to raise enough cash to scale quickly while simultaneously minimizing risk. Marty needed to employ the business acumen necessary to slow down, consider the pros and cons, and make the best decision for his company. The educational focus of this case involves weighing the entrepreneurial risks and rewards of pursuing a deal with a large retailer like Walmart. While this type of opportunity may seem exciting at first glance, a variety of factors must be considered in order to find a thoughtful and sensible path forward.


2000 ◽  
Vol 29 (4) ◽  
pp. 602-606
Author(s):  
Sachiko Ide

The assumptions made by readers of Language in Society and other English-language academic publications, when they begin to read, are so widely shared that they are seldom reflected on or made explicit. These assumptions have to do with European traditions of scholarship; and over time, they have made their way around the world because of the unquestioned belief in their universal applicability. But other approaches do exist, although most are never featured in publications in Western languages. I commented on this situation long ago, but it persists to this day: “The work done by Japanese sociolinguists is virtually unknown to non-Japanese readers. The reason is probably that this work has developed independently of the Western disciplines. The fact that Japanese researchers have worked independently of the Western tradition has inevitably resulted in unique assumptions, orientations or approaches when viewed from an international perspective”.


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