Pharmacognostic and Therapeutic Activities of Genus Ocimum.

2020 ◽  
Vol 18 ◽  
Author(s):  
Prerna Sharma ◽  
Kumud Upadhyaya
Keyword(s):  
Antibacterial Activity ◽  
Active Ingredient ◽  
Therapeutic Agent ◽  
Drug Distribution ◽  
Entire Population ◽  
Crude Drug ◽  
The Future ◽  
Therapeutic Activities

Objective: The main objective of this review is to provide a platform to learn about the importance of Ocimum. A genus known to the entire population of India as Tulsi. Special attention has been paid to literature reports describing the use of Tulsi and cancer. Methods: The importance of the plant and the active ingredient is described here in the relevant bibliographic references. The use of the plant would be much more important for the drug distribution scientist to develop a special formulation of the crude drug, which in the future will be a magical therapeutic agent with many benefits. Results and Conclusion: Examples have been presented in which the plant is used and its use in its antibacterial activity.

scholarly journals Studies on the chinese crude drug "forsythiae fructus." VI. The structure and antibacterial activity of suspensaside isolated from forsythia suspensa.

1982 ◽  
Vol 30 (12) ◽  
pp. 4548-4553 ◽  
Author(s):  
SANSEI NISHIBE ◽  
KAZUKO OKABE ◽  
HIROKI TSUKAMOTO ◽  
AKIYO SAKUSHIMA ◽  
SUEO HISADA ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Crude Drug ◽  
Forsythia Suspensa

The antibacterial activity expressed in vitro and in vivo by Lactococcus lactis subsp. lactis CNRZ 1427 against Salmonella sp.

2015 ◽  
Vol 4 (5) ◽  
pp. 240-246
Author(s):  
Menad Najett ◽  
Chougrani Fadelaa ◽  
Moghtet Snoussi ◽  
Cheriguene Abderrahim
Keyword(s):  
Antibacterial Activity ◽  
Lactococcus Lactis ◽  
Bile Salts ◽  
Therapeutic Agent ◽  
Lactococcus Lactis Subsp ◽  
Beneficial Effects ◽  
Gastrointestinal Conditions ◽  
Therapeutic Possibilities

  The present study focused on the beneficial effects of Lactococcus lactis subsp lactis CNRZ 1427 with possible use as a therapeutic agent against Sal-monella sp.; also we have proposed different therapeutic possibilities of our situation against a pathogen Salmonella sp. We have conducted two tests In Vitro and In Vivo; where it is noted that treatment in the presence of this lac-tic strain is effective since it causes a remarkable decrease of the pathogen agent. At the end, the effectiveness of this lactic strain was confirmed by testing for resistance to gastrointestinal conditions (pH, bile salts and diges-tive enzymes).

scholarly journals Phage Therapy with a focus on the Human Microbiota

Antibiotics ◽  
2019 ◽  
Vol 8 (3) ◽  
pp. 131 ◽  
Author(s):  
Ganeshan ◽  
Hosseinidoust
Keyword(s):  
Infectious Disease ◽  
Antibacterial Activity ◽  
Antibiotic Resistance ◽  
Therapeutic Agent ◽  
Phage Therapy ◽  
Arms Race ◽  
Phage Resistance ◽  
Bacteriophage Therapy ◽  
Human Gut ◽  
Human Microbiota

Bacteriophages are viruses that infect bacteria. After their discovery in the early 1900s, bacteriophages were a primary cure against infectious disease for almost 25 years, before being completely overshadowed by antibiotics. With the rise of antibiotic resistance, bacteriophages are being explored again for their antibacterial activity. One of the critical apprehensions regarding bacteriophage therapy, however, is the possibility of genome evolution, development of phage resistance, and subsequent perturbations to our microbiota. Through this review, we set out to explore the principles supporting the use of bacteriophages as a therapeutic agent, discuss the human gut microbiome in relation to the utilization of phage therapy, and the co-evolutionary arms race between host bacteria and phage in the context of the human microbiota.

An edible film of sodium alginate/pullulan incorporated with capsaicin

2018 ◽  
Vol 42 (21) ◽  
pp. 17756-17761 ◽  
Author(s):  
Shen Zhang ◽  
Feng Wei ◽  
Xiaojun Han
Keyword(s):  
Antibacterial Activity ◽  
Sodium Alginate ◽  
Active Ingredient ◽  
Edible Film ◽  
Red Pepper

Capsaicin, an active ingredient in red pepper, shows great antibacterial activity.

scholarly journals Pengaruh Ekstrak Etanolik Kulit Batang Jambu Mete (Anacardium occidentale Linn) sebagai Bahan Kumur terhadap Daya Perlekatan C. Albicans pada Plat Resin Akrilik

2016 ◽  
Vol 19 (1) ◽  
pp. 137
Author(s):  
H. Harsini
Keyword(s):  
Antibacterial Activity ◽  
Antibacterial Agent ◽  
Therapeutic Agent ◽  
Negative Control ◽  
Anacardium Occidentale ◽  
Bark Extract ◽  
Acrylic Plate ◽  
One Way Anova ◽  
Candia Albicans ◽  
Made In

Latar Belakang: Candia albicans adalah mikroorganisme yang berkoloni melekat pada permukaan gigi maupun gigi tiruan. Obat kumur mengandung bahan tarapeutik yang berfungsi sebagai antibakteri. Kulit batang jambu mete antara lain mengandung senyawa fenolik yang dapat berkhasiat sebagai antibakteri. Tujuan penelitian: Untuk mengetahui apakah ekstrak etanolik kulit batang jambu mete sebagai bahan kumur berpengaruh terhadap gaya perlekatan C. Albicans pada plat resin akrilik. Metode penelitian: Ekstrak kulit batang jambu mete diperoleh dengan menggunakan metode maserasi dan menggunakan etanol sebagai pelarut. Bahan kumur ekstrak kulit batang jambu mete dibuat dengan komposisi bahan kumur standar dengan menambahkan ekstrak etanolik kulit batang jambu mete dengan konsentrasi 1%, 2%, 3%, 4%, dan 5% sebagai agen antibakteri. Penelitian dilakukan dengan menggunakan plat resin akrilik yang dibuat bentuk disk dengan ukuran diameter 10 mm dan tebal 2 mm sebanyak 24 buah, yang dibagi dalam 6 kelompok yaitu 5 kelompok perlakuan dengan menggunakan bahan kumur yang mengandung ekstrak kulit batang jambu mete dan 1 kelompok kontrol menggunakan bahan kumur standar. Seluruh plat resin dimasukkan dalam tabung C. Albicans 10 CFU/ml selama 5 menit, kemudian plat diambil dan dimasukkan dalam larutan bahan kumur standar sebagai kontrol dan larutan bahan kumur yang mengandung ekstrak kulit batang jambu mete untuk kelompok perlakuan selama 3 menit dan digetarkan. Cairan kemudian diambil sebanyak 0,1 ml dan ditanam pada piring petri dengan agar saboruraud dan diinkubasi selama 48 jam. Perhitungan koloni dilakukan menggunakan counter. Hasil penelitian: Hasil daya perlekatan pada bahan kumur standar 1912,50±14,93; pada bahan kumur dengan ekstrak 1% = 1757,50±20,16; 2% = 1335±17,08; 3% = 1220; 4% = 915±22,17 dan 5% = 670,00±38,37. Analisis varian satu jalur memperlihatkan pengaruh yang bermakna ekstrak etanolik kulit batang jambu mete terhadap daya lekat C. Albicans pada plat resin akrilik (p<0,05). Hasil LSD menunjukkan bahwa terdapat perbedaan yang bermakna antar seluruh kelompok perlakuan (p<0,05). Kesimpulan: Ekstrak etanolik kulit batang jambu mete sebagai bahan kumur berpengaruh terhadap daya perlekatan C. Albicans pada plat resin aklirik. Background: C. Albicans is a microorganism which colonized on the tooth or denture prosthesis surfaces. Mouthwashes usually contain therapeutic agent as antibacterial. The bark of Annacardium occidentale contains fenolic as antibacterial activity. The aim of this research was to determine the influence of the etanolic ectract of anacardium occidentale bark as mouthwashes on C. Albicans adherence. Method: the extract of anacardium occidentale bark was conducted in maceration method and used ethanol as solvent. Mouthwashes were made in standart composition and added annacardium occidentale bark extract 1%, 2%, 3%, 4% and 5% as antibacterial agent. As a negative control was used standart mouthwashes without extract. The research used 24 resin acrylic which made in disk shape with diameter 10 mm. This acrylic were divided in 6 group, there were 5 group treated with mouthwash that contain extract anacardium occidentale bark and 1 group treated with standart mouthwashes. All of resins plate were incubated in C. Albicans solution for 5 minute. After that resin acrylic plate were immersed in standart mouthwashes as a control and mouthwashes with anaracium occidentale bark extract and vibrate for 3 minutes. The solution then taken 0,1 ml and planted in petry dish with saboruraud agar and incubated for 48 hours. Result: Attachment of candida alvicans was: 1912,50±14,93 as control and mouthwash with extract were 1% = 1757,50±20,16; 2% = 1335±17,08; 3% = 1220; 4% = 915±22,17 and 5% = 670,00±38,37. Analyzed with one way Anova showed that the extract of annaracium occidentale bark as mouthwash influenced the cancida albicans adherence on resin acrylic surface (p<0,05). LSD analyzed showed there were significant differenced between all groups (p<0,05). Conclusion: The extract of anacardium occidentale bark extract as mouthwash were influence of the C. Albicans adherence on resin acrylic surface.

scholarly journals A Review on the Medicinal and Aromatic Plants Growing in Libya and Their Therapeutic Properties.

2020 ◽  
pp. 327-334 ◽  
Author(s):  
Abdullah F Abogmaza ◽  
Kheri F Keer ◽  
Ayad A Takrizzah ◽  
Esam Bashir Yahya
Keyword(s):  
Medicinal Plants ◽  
Therapeutic Agent ◽  
Biological Activities ◽  
Therapeutic Option ◽  
Food Preservation ◽  
Aromatic Plants ◽  
Medicinal And Aromatic Plants ◽  
Traditional Use ◽  
Therapeutic Properties ◽  
Therapeutic Activities

Plants are a rich source of diverse metabolites that have been traditionally used for thousands of years all over the world, providing safer and inexpensive therapeutic option for millions of people in developing countries including Libya. Many types of medicinal plants growing in Libya possess significantly important curative activities and have been traditionally used for treatment of chronic diseases such as diabetes and cancer, as well as their biological activities such as antibacterial, antifungal, antiparasitic and insecticidal properties, etc. Apart from the therapeutic activities, most of Libyan nation rather to use natural and plant-based materials for their daily activities such as food preservation, food flavoring as well as medicinal usages. This review presents the most important medicinal plants growing in Libya with their traditional usage, medical properties, and compare the reliability of using these plants as therapeutic agents. Presenting the latest works that have been done in term of justification of the traditional use and scientifically proving its ability as therapeutic agent

scholarly journals Synthesis and Biological Screening of 3-Aryl-5-[(4′-Difluoromethoxy)(3′-Hydroxy)Phenyl]-4,5-Dihydro Isoxazole

2015 ◽  
Vol 47 ◽  
pp. 133-138
Author(s):  
V.N. Bhadani ◽  
H.D. Purohit ◽  
Dipak M. Purohit
Keyword(s):  
Antibacterial Activity ◽  
Candida Albicans ◽  
Antifungal Activity ◽  
Biological Activities ◽  
Gram Negative Bacteria ◽  
Biological Screening ◽  
Gram Negative ◽  
E Coli ◽  
Gram Positive Bacteria ◽  
Therapeutic Activities

Isoxazoline derivatives shows various types of therapeutic activities like antimicrobial[1], anti-inflammatory[2], anticonvulsant[3], Hypoglycemic[4] etc. getting to synthesized in view of 3-Aryl-5-[(4′-difluoromethoxy)(3′-hydroxy)phenyl]-4,5-dihydro isoxazole (4a-4i) have been synthesized. All the newly synthesized compounds were screened for their antibacterial activity against S. aureus, M. luteus (Gram-positive bacteria), E. coli, S. thyphi (Gram-negative bacteria) and antifungal activity against Candida albicans (Fungi). The biological activities (MIC) of the synthesized compounds were compared with known standard drugs.

scholarly journals PERANAN HAKIM DALAM PEMBERANTASAN TINDAK PIDANA NARKOBA MELALUI PUTUSAN YANG BERKEADILAN

2017 ◽  
Vol 6 (2) ◽  
pp. 259
Author(s):  
Oksidelfa Yanto
Keyword(s):  
Drug Abuse ◽  
Law Enforcement ◽  
Drug Trafficking ◽  
Social Life ◽  
Drug Distribution ◽  
Population Number ◽  
The World ◽  
The Future ◽  
Supreme Commander

Indonesia is the fourth largest country in the capacity of the population number in the world. As the country with the largest population, various problems often plague the nation of Indonesia. One such problem is the problem of law enforcement and narcotics and drugs cases. Up to now Indonesia is confronted with drug trafficking that is very alarming. Drug crimes are so uncontrolled in social life. It is undeniable that narcotics have been threatening the future of the nation. There have been already many victims even until some of them dies. Drug abuse has reached very dangerous phase. There is no other way, government and officials must immediately take a serious and earnest step. It is a pity that the nation's children must always be the victims of drug distribution by the syndicate. Laws must be enforced as fairly as possible. Because the law is the supreme commander that must not be defeated by anything.Keywords: role of the judge, crime, drugs

Design, Molecular Docking, Synthesis and Biological Evaluation of 4, 5-Substituted 1, 2, 3-Triazoles as Anti-bacterial Agents

2021 ◽  
Vol 14 (2) ◽  
pp. 5372-5383
Author(s):  
Vijayabhargavi M ◽  
Kusuma M. P. ◽  
Akhila Sai ◽  
Sumakanth M ◽  
Zaber Unnisa
Keyword(s):  
Antibacterial Activity ◽  
Bacterial Infections ◽  
Thiophene Ring ◽  
Docking Studies ◽  
Biological Evaluation ◽  
In Silico Docking ◽  
E Coli ◽  
Gram Positive Bacteria ◽  
Therapeutic Activities ◽  
Substituted 1

Newer antibacterial agents are needed to combat the growing bacterial infections. Triazoles are one of the leading and most sought out nucleus amongst the heterocyclic rings in the drug world. 1, 2, 3-Triazoles are synthesized by Click Chemistry of alkynes with azides. A synergistic effect is observed when the triazoles are combined with other heterocycles. They also exhibit diversified therapeutic activities like anti-viral, anti-bacterial, anti-diabetic, anti-tubercular, anti-inflam-matory, antihypertensive etc which makes Triazoles an interesting molecule for the researchers to work on. In the current study, we combined 1,2, 3-triazoles with thiophene ring system to get synergistic antibacterial activity. Here, 12 derivatives of 4, 5-substituted-1, 2, 3-Triazoles were subjected to in silico docking studies on Biotin ligase protein (PDB ID: 3V7R). The compounds that showed the best results were synthesized. The newly synthesized derivatives were characterized by using IR, H1 NMR and Mass spectrum. All the synthesized derivatives were evaluated for antibacterial activity against Gram-negative bacteria (E. coli and P. aerugenosa) and gram-positive bacteria (B. subtilis and S. aureus). The compounds showed moderate to good activity, which was comparable to that of the standard Streptomycin drug.

Sign in / Sign up

Export Citation Format

Share Document