Evaluation of Response Surface Methodology to Predict Optimum Growth Conditions for Lactobacillus plantarum A7 (KC 355240) in Probiotic Soy Milk Containing Essential Oil of Cuminum cyminum

2016 ◽  
Vol 8 (2) ◽  
pp. 132-137 ◽  
Author(s):  
Mina Babashahi ◽  
Maryam Mirlohi ◽  
Reza Ghiasvand ◽  
Sahar Torki-Baghbadorani
Keyword(s):  
Response Surface Methodology ◽  
Essential Oil ◽  
Response Surface ◽  
Lactobacillus Plantarum ◽  
Growth Conditions ◽  
Optimum Growth ◽  
Soy Milk ◽  
Cuminum Cyminum

Response Surface Methodology towards Optimization of Calotropis Procera Essential oil Extraction by using Supercritical CO2.

2019 ◽  
Vol 09 ◽  
Author(s):  
Hossein Zaeri ◽  
Bahareh Kamyab Moghadas ◽  
Bijan Honarvar ◽  
Ali Shokuhi Rad
Keyword(s):  
Response Surface Methodology ◽  
Essential Oil ◽  
Response Surface ◽  
Extraction Time ◽  
Calotropis Procera ◽  
Retrieval Rate ◽  
The Family ◽  
Effects Of Temperature ◽  
Carbon Dioxide Co2 ◽  
Central Composite

: In this research, the extraction of essential oil from Calotropis Procera with the family name of Asclepiadaceae, by supercritical carbon dioxide (CO2) solvent has been investigated in detail, and the yield and chemical profile of the extracts achieved by this method were compared with those resulted by the conventional Hydro distillation method. To optimize the process parameters of CO2 supercritical extraction (SCE) of the Calotropis Procera, the Response Surface Methodology (RSM) with central composite design (CCD) was employed. The effects of temperature, pressure, and extraction time on the oil yield are considered for investigation. Results showed that the data were sufficiently fitted into the second-order polynomial model. The extraction conditions, including pressure, temperature, and extraction time, were studied between 150-200 bar, 40-50 ºC, and 50-100 min, respectively. The optimal conditions are achieved as the temperature of 47.19ºC, the pressure of 172.2 bar, and time of 86 minutes with the retrieval rate of 31.39%.

scholarly journals Extraction of ‘Gannanzao’ Orange Peel Essential Oil by Response Surface Methodology and its Effect on Cancer Cell Proliferation and Migration

Molecules ◽  
2019 ◽  
Vol 24 (3) ◽  
pp. 499 ◽  
Author(s):  
Ke Liu ◽  
Weihui Deng ◽  
Wei Hu ◽  
Shan Cao ◽  
Balian Zhong ◽  
...  
Keyword(s):  
Response Surface Methodology ◽  
Essential Oil ◽  
Cancer Cells ◽  
Response Surface ◽  
Chloride Concentration ◽  
Orange Peel ◽  
Cell Counting ◽  
Dependent Inhibition ◽  
And Migration ◽  
Total Oil

The essential oil of ‘Gannanzao’ orange peel was extracted by hydrodistillation, and the extraction conditions were optimized by Box–Behnken response surface methodology. The components of essential oil were analyzed by GC-MS. Thirty-nine different components were detected, accounting for 99.59% of the total oil. Limonene (88.07%) was the prominent component. The optimal extraction conditions were as follows: liquid material ratio of 8.4:1 (mL/g), sodium chloride concentration of 5.3%, and distillation time of 3.5 h. The Cell Counting Kit-8 assay showed that ‘Gannanzao’ orange peel essential oil had good dose-dependent inhibition effect on the proliferation of HepG2 hepatoma cells and HCT116 colorectal cancer cells. When the concentration of the essential oil was 0.6 μL/mL or higher, the viability rate of both cancer cells became lower than 13.0%. The transwell assay indicated the essential oil can inhibit migration of both cancer cells at the concentration of 0.3 μL/mL.

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