scholarly journals Combined effectiveness of Maharasnadi Kashaya with Shunti Churna and Matra Basti with Ksheerabala Taila in Janu Sandhigata Vata (Osteoarthritis Knee) : An open label, single arm clinical study

2020 ◽  
Vol 5 (04) ◽  
pp. 62-67
Author(s):  
Kiran K ◽  
Vasantha B ◽  
Muttappa Totad
Keyword(s):  
Risk Factors ◽  
Clinical Study ◽  
Knee Joint ◽  
Knee Osteoarthritis ◽  
Signs And Symptoms ◽  
Osteoarthritis Of The Knee ◽  
Open Label ◽  
Factors Associated ◽  
Osteoarthritis Of Knee ◽  
Osteoarthritis Knee

Sandhi Gata Vata is a clinical condition that comes under the heading of Vata Vyadhi where Prakupita Vata affects Sandhi and causes specific signs and symptoms. Lakshanas of Sandhi Gata Vata of Janu Sandhi resembles the signs and symptoms of osteoarthritis of knee. Osteoarthritis of the knee is more commonly found in women than men, and the prevalence increases dramatically with age. The major risk factors associated with osteoarthritis knee joint are old age, obesity, excessive usage of knee joint (occupational), which makes it an important cause of disability. A clinical study was conducted on 31 subjects by administering combination of Maharsnadi Kashaya with Shunti Churna and Matra Basti with Ksheerabala Taila and the results obtained were statistically analysed. Statistically significant reduction in Lakshanas of Janu Sandhi Gata Vata and WOMAC scores were noted.

scholarly journals EFFICACY OF ERANDAMOOLADI BASTI IN THE MANAGEMENT OF JANU SANDHIGATAVATA VIS-A-VIS OSTEOARTHRITIS OF KNEE JOINT – AN OBSERVATIONAL CLINICAL STUDY

2021 ◽  
Vol 9 (2) ◽  
pp. 360-366
Author(s):  
S Jagadesh Kumar ◽  
Shreyas D M ◽  
Kiran M Goud
Keyword(s):  
Adverse Effect ◽  
Clinical Study ◽  
Knee Joint ◽  
Knee Osteoarthritis ◽  
Surgical Intervention ◽  
Limited Range ◽  
Daily Activities ◽  
Osteoarthritis Of Knee ◽  
Dual Action ◽  
The Individual

Janu Sandhigata vata is one such Vatavyadhi presenting with Sandhi shula, Sandhi shotha, Sandhi atopa and Prasarana Akunchana Vedana, resulting in limited range of movements, there by restricting daily activities of the individual. Janu Sandhigatavata is commonly identified with Osteoarthritis of Knee Joint characterized by pain, swelling & impaired movements. The prevalence of Osteoarthritis rises progressively with age and it has been estimated that that 45% of all people develop Knee Osteoarthritis in life. Osteoarthritis is more common in women than men. The existent line of treatment in contemporary field of medicine includes the administration of analgesics, NSAIDS, Intra articular steroids and surgical intervention in the form of Knee replacement, which all has their own limitation and meanwhile may have deleterious adverse effect. In this regard, there is a need for exploring the safe, effective and affordable line of treatment. Basti karma is a supreme treatment for Vata Vyadhi and also known as Ardha Chikitsa because of its multifaceted actions. Many Basti formulations are mentioned in classics among which Erandamooladi Bati was selected for the study because its dual action, does Vataghna and also relives Kapha Avarana. The results were statistically highly significant within the group.

Intra-articular gold induced cytokine (GOLDIC®) injection therapy in patients with osteoarthritis of knee joint: a clinical study

2021 ◽  
Author(s):  
Ulrich Schneider ◽  
Ashok Kumar ◽  
William Murrell ◽  
Agnes Ezekwesili ◽  
Nagib A. Yurdi ◽  
...  
Keyword(s):  
Clinical Study ◽  
Knee Joint ◽  
Injection Therapy ◽  
Osteoarthritis Of Knee

scholarly journals An open label single arm prospective clinical study on Vatagajankusharasa with Pippali Churna and Manjishta Kwatha as Anupana in Viswachi (cervical spondylosis)

2020 ◽  
Vol 5 (01) ◽  
pp. 73-80
Author(s):  
Moh Gulfam ◽  
Totad Muttappa ◽  
Neelam Bisht ◽  
Vishnu M L ◽  
Yadu Gopan
Keyword(s):  
Clinical Study ◽  
Ordinal Data ◽  
Cervical Spondylosis ◽  
Signs And Symptoms ◽  
Upper Extremities ◽  
Secondary Outcome ◽  
Prospective Clinical Study ◽  
Rank Tests ◽  
Open Label ◽  
Signed Rank

Background: Viswachi is one among the 80 Nanatmaja Vata Vyadhi. This disease affects the neck and upper extremities with the signs and symptoms like Ruk, Stambha, Toda, Bahu Karmakshaya. Vatagajankusha Rasa is a combination of Vyosha, Bhasmas, Vatsanabha, Karkatasringi, Haritaki etc. It has Vatakaphahara, Vikasi, Vyavayi, Rasayana etc. properties. It is said to be effective in treating Visawachi in 7 days if given along with Pippali Churna and Manjishta Kwatha. Aims and Objectives: To evaluate the efficacy of Vatagajankusha Rasa with Pippali Churna and Manjishta Kwatha as Anupana in the management of Viswachi (Cervical spondylosis). Methodology: Among 35 registered patients, 30 completed the course of treatment. They were administered with Vatagajankusha Rasa 1 tablet (125 mg) after food with Anupana 3gm Pippali Churna and 15 ml Manjishta Kwatha twice daily (morning and evening) for a period of 7 days. Nominal and ordinal data were analysed using non parametric tests like McNemar and Wilcoxon’s signed rank tests respectively. Result: Assessment parameters like Ruk, Toda, Sthambha and Bahukarma Kshya. There was statistically significant improvement in the primary and secondary outcome measures (p less than 0.05 was observed). Conclusion: Vatagajankusha Rasa with Pippali Churna and Manjishta Kwatha as Anupana is effective in the management of Viswachi (Cervical spondylosis).

scholarly journals Research Progress on Acupuncture Treatment of Knee Osteoarthritis

2021 ◽  
Vol 9 (4) ◽  
pp. 106-110
Author(s):  
Zhang Yueyu ◽  
Song Aiqun ◽  
Peng Ying
Keyword(s):  
Acupuncture Therapy ◽  
Knee Joint ◽  
Knee Osteoarthritis ◽  
Joint Pain ◽  
Acupuncture Treatment ◽  
Treatment Plan ◽  
Joint Inflammation ◽  
Research Progress ◽  
Osteoarthritis Of The Knee ◽  
Joint Function

Osteoarthritis of the knee is a common clinical degenerative disease, which occurs in middle-aged and elderly people. Acupuncture therapy has a significant effect in the treatment of knee osteoarthritis, and is gradually accepted by more and more patients. Observing the treatment of knee osteoarthritis by different acupuncture and moxibustion therapies, we can find that acupuncture treatment of knee osteoarthritis has the advantages of relieving knee joint pain, improving knee joint function, absorbing knee joint inflammation, and promoting the recovery of damaged soft tissue. The treatment of osteoarthritis provides a more effective treatment plan.

scholarly journals 2193. Factors Impacting the Duration of Antimicrobial Therapy for Community-Acquired Pneumonia

2019 ◽  
Vol 6 (Supplement_2) ◽  
pp. S746-S747
Author(s):  
Avnish Sandhu ◽  
Erin Goldman ◽  
Jordan Polistico ◽  
Sarah Polistico ◽  
Ahmed Oudeif ◽  
...  
Keyword(s):  
Risk Factors ◽  
Medical Center ◽  
Clinical Signs ◽  
Retrospective Chart Review ◽  
Signs And Symptoms ◽  
Community Acquired Pneumonia ◽  
Prescribing Patterns ◽  
Antibiotic Prescribing ◽  
Factors Associated ◽  
Specific Risk

Abstract Background Pneumonia is a common cause of infection associated with hospitalization. Treatment durations for community-acquired pneumonia (CAP) often exceed guideline recommended durations of 5–7 days without a clear explanation. The objective of this study was to determine factors that may lead to durations exceeding this recommendation. Methods A retrospective chart review of 89 patients admitted to the Detroit Medical Center (DMC) for the treatment of pneumonia was conducted. Demographics, clinical signs and symptoms, antibiotic data, pneumonia severity score (CURB 65), risk factors for resistance, microbiology results, and outcomes were recorded and analyzed for factors associated with increased durations of antibiotics. Average durations of antibiotics and durations of antibiotics greater that 7 days were assessed for each risk factor. Results Average durations of antibiotics was 9 days (SD 3.8) for the cohort, and 55 (61%) received durations of > 7 days. Average durations of antibiotics for risk factors are shown in Table 1. Factors associated with durations of antibiotics longer than 7 days are shown in Table 2. There was a trend toward longer average durations of antibiotics for persons with risk factors for resistance [Drug Resistance in Pneumonia (DRIP) score ≥ 4 (increased duration of antibiotics by 1.7 days, P = 0.07] and those with a positive legionella antigen [increased durations of antibiotics by 6.6 days, P = 0.07]. Conclusion Specific risk factors could not be associated with increased durations of antibiotics, although there was a trend toward longer durations for persons with markers for resistance and positive legionella testing. Efforts to reduce durations of antibiotics must target global clinician antibiotic prescribing patterns and not specific risk factors. Disclosures All authors: No reported disclosures.

Risk factors associated with early implant failure: A 5-year retrospective clinical study

2016 ◽  
Vol 115 (2) ◽  
pp. 150-155 ◽  
Author(s):  
Maris Victoria Olmedo-Gaya ◽  
Francisco J. Manzano-Moreno ◽  
Esther Cañaveral-Cavero ◽  
Juan de Dios Luna-del Castillo ◽  
Manuel Vallecillo-Capilla
Keyword(s):  
Risk Factors ◽  
Clinical Study ◽  
Implant Failure ◽  
Factors Associated ◽  
Retrospective Clinical Study

scholarly journals Effect of Yoga Basti in Sandhivata w.s.r. to Osteoarthritis of Knee joint

2017 ◽  
Vol 8 (2) ◽  
Author(s):  
Daksha Rathod ◽  
Kalpesh Dattani
Keyword(s):  
Knee Joint ◽  
Clinical Signs ◽  
Signs And Symptoms ◽  
Inclusion Criteria ◽  
Single Group ◽  
Osteoarthritis Of Knee ◽  
Clinical Signs And Symptoms ◽  
The Given ◽  
Marked Relief ◽  
Joint Method

Sandhivata (Osteoarthritis) is one of the Vataja vyadhi (disease due to Vata Dosha) and most common degenerative disease seen in old age people. The Ayurvedic approach to the management of Sandhivata is to provide the complete cure. Objective of the present study was to evaluate the effect of Erandamooladi Niruha Basti and Dashamooladi Anuvasana Basti as Yoga Basti in Sandhivata w.s.r to osteoarthritis of knee joint. Method: 30 patients fulfilling the inclusion criteria of Sandhivata were randomly selected in a single group and treated with Yoga Basti [Dashmooladi Anuvasan Basti and Erandmooladi Niruha Basti]  daily in the morning  for a period of 8  days. Clinical signs and symptoms were given suitable scores according to their severity and assessed based on pre and post data gathered through pre-designed research clinical proforma. The results having ‘P’ value less than 0.0001 was considered to be statistically significant in this study. Result: All the patients in the group showed highly significant improvement in all the symptoms. Pain relieved 80.77%, stiffness  relieved 84.39%, fatigue relieved 100%, restricted movement  reduced by 100 % and deformity reduced by 74.15%. Conclusion: Yoga Basti is found effective in the management of Sandhivata with reference to osteoarthritis of knee joint.All the patients responded to the given treatment without any adverse effects and complications. Mild to marked relief was found in all the symptoms of Sandhivata . 

scholarly journals Risk factors associated with COVID-19 Intensive Care Unit hospitalisation in Guyana: A cross-sectional study

2021 ◽  
Author(s):  
Steven A. Seepersaud
Keyword(s):  
Risk Factors ◽  
Retrospective Chart Review ◽  
Binary Logistic Regression ◽  
Signs And Symptoms ◽  
Cross Sectional Study ◽  
Laboratory Findings ◽  
Cross Sectional ◽  
Factors Associated ◽  
Independent Variables ◽  
Icu Admission

Objective The purpose of the study was to determine risk factors associated with COVID-19 ICU hospitalisation at Georgetown Public Hospital Corporation (GPHC), Guyana. Methods A retrospective chart-review was conducted on all COVID-19 admissions from March to September 2020. The predictive factors were demographics, comorbidities, signs and symptoms of COVID-19 and laboratory findings on admission. Descriptive frequency analysis was done for all independent variables and the Chi-square test was used to compare differences between groups where suitable. Univariate and multivariate binary logistic regression was used to examine the association between the independent variables and the risk for ICU hospitalisation. Results There were 136 patients with COVID-19 at GPHC during March to September 2020 and after exclusion, 135 patients were used in the study. There were 72 (53.4%) patients who required non-ICU care, while 63 (46.6%) ICU care and average age ± SD (median) was 51 ±16 (n= 49) and 56 ±18 (n= 60), respectively. In the multivariate regression model, the odds of ICU admission for those aged 40-65 was 0.14 (p <.01) compared to those > 65 years. Patients with class 2 and above obesity had higher odds of ICU admission compared to non-obese patients OR 11.09 (p= .006). Patients with 2 and 3 or more comorbidities also had higher odds of ICU admission compared to those with no comorbidities OR 7.83 (p= .03) and 132 (p <.001), respectively. Patients with LDH 228-454 U/L and > 454 U/L on admission had higher odds of ICU admission compared to those with normal LDH OR 19.88 (p= .001) and 23.32 (p= .001), respectively. Patients with albumin < 3.50 mg/dL on admission also had higher odds of ICU admission compared to those with normal albumin OR 5.78 (p= .005). Conclusion Risk factors associated with ICU hospitalisation were advanced age, obesity, multiple comorbidities, elevated LDH and low albumin. Protecting the population at risk for ICU admission and prioritizing them for vaccination is recommended to reduce the risk of running out of ICU capacity.

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