Observational study on Barium Meal X-Ray in clinically diagnosed cases of Parinama Shoola

2016 ◽  
Vol 1 (2) ◽  
Author(s):  
Dr. Mahamad Yunus ◽  
KM Shailaja Singh ◽  
Suvarna Bhagavat ◽  
Arun Kumar Singh ◽  
Manish Kumar
Keyword(s):  
Medical Science ◽  
Duodenal Bulb ◽  
Barium Meal ◽  
Vital Role ◽  
Question Mark ◽  
X Ray ◽  
System Disease ◽  
Mucosal Erosion ◽  
Meal Time ◽  
The Mind

Parinama Shoola is a disease of Annavaha Srotas (GIT) characterized by pain during digestion of food which tormates the process after every meal time and source of constant discomfort. It is a Pitta Pradhana Tridoshaja Vyadhi. Based on subjective features most of the Ayurvedic scholars considered as peptic ulcer, one of the most common digestive system disease rise due to the faulty diet and habits. Hence in the field of gastroenterology diagnosis and management of shoola plays a vital role. The present era is an era of new inventions and the modern medical science has stuck the mind of all by its day to day developments. It is true that modern medical science has grown up considerably; still it has to face a big question mark in so far as some miserable problems are concerned. The problem selected for this work is one among them. Considering the solemnity and incidence of the disease, the present study was aimed to observe barium meal X-ray findings in clinically diagnosed cases of Parinama Shoola to evaluate objective features for Parinama Shoola. It was observed that among 60 patients of Parinama Shoola, 30% were having deformed duodenal bulb, in 25% duodenal cap is deformed with mucosal erosion and 13.3% had duodenal ulcer found with ulcer crater in upper GI barium meal X-ray.

The Value of Neuroimaging Techniques in the Translation and Transdiagnostic Validation of Psychiatric Diagnoses - Selective Review

2020 ◽  
Vol 20 (7) ◽  
pp. 540-553 ◽  
Author(s):  
Anna Todeva-Radneva ◽  
Rositsa Paunova ◽  
Sevdalina Kandilarova ◽  
Drozdstoy St. Stoyanov
Keyword(s):  
Psychiatric Disorders ◽  
Psychiatric Symptoms ◽  
Medical Science ◽  
Self Report ◽  
Current Status ◽  
Diagnostic Tools ◽  
Main Concept ◽  
Directional Change ◽  
The Mind ◽  
Neuroimaging Techniques

: Psychiatric diagnosis has long been perceived as more of an art than a science since its foundations lie within the observation, and the self-report of the patients themselves and objective diagnostic biomarkers are lacking. Furthermore, the diagnostic tools in use not only stray away from the conventional medical framework but also remain invalidated with evidence-based concepts. However, neuroscience, as a source of valid objective knowledge has initiated the process of a paradigm shift underlined by the main concept of psychiatric disorders being “brain disorders”. It is also a bridge closing the explanatory gap among the different fields of medicine via the translation of the knowledge within a multidisciplinary framework. : The contemporary neuroimaging methods, such as fMRI provide researchers with an entirely new set of tools to reform the current status quo by creating an opportunity to define and validate objective biomarkers that can be translated into clinical practice. Combining multiple neuroimaging techniques with the knowledge of the role of genetic factors, neurochemical imbalance and neuroinflammatory processes in the etiopathophysiology of psychiatric disorders is a step towards a comprehensive biological explanation of psychiatric disorders and a final differentiation of psychiatry as a well-founded medical science. : In addition, the neuroscientific knowledge gained thus far suggests a necessity for directional change to exploring multidisciplinary concepts, such as multiple causality and dimensionality of psychiatric symptoms and disorders. A concomitant viewpoint transition of the notion of validity in psychiatry with a focus on an integrative validatory approach may facilitate the building of a collaborative bridge above the wall existing between the scientific fields analyzing the mind and those studying the brain.

Recent Development of Small Molecule Glutaminase Inhibitors

2018 ◽  
Vol 18 (6) ◽  
pp. 432-443 ◽  
Author(s):  
Minsoo Song ◽  
Soong-Hyun Kim ◽  
Chun Young Im ◽  
Hee-Jong Hwang
Keyword(s):  
Small Molecule ◽  
Cell Metabolism ◽  
Phase 1 ◽  
Vital Role ◽  
Glutamine Metabolism ◽  
Inhibition Mechanism ◽  
Tumor Cell Growth ◽  
X Ray ◽  
New Class ◽  
Preclinical And Clinical Studies

Glutaminase (GLS), which is responsible for the conversion of glutamine to glutamate, plays a vital role in up-regulating cell metabolism for tumor cell growth and is considered to be a valuable therapeutic target for cancer treatment. Based on this important function of glutaminase in cancer, several GLS inhibitors have been developed in both academia and industry. Most importantly, Calithera Biosciences Inc. is actively developing the glutaminase inhibitor CB-839 for the treatment of various cancers, and it is currently being evaluated in phase 1 and 2 clinical trials. In this review, recent efforts to develop small molecule glutaminase inhibitors that target glutamine metabolism in both preclinical and clinical studies are discussed. In particular, more emphasis is placed on CB-839 because it is the only small molecule GLS inhibitor being studied in a clinical setting. The inhibition mechanism is also discussed based on X-ray structure studies of thiadiazole derivatives present in glutaminase inhibitor BPTES. Finally, recent medicinal chemistry efforts to develop a new class of GLS inhibitors are described in the hopes of providing useful information for the next generation of GLS inhibitors.

Biomimicry: An Overview of Structures, Designs and Materials Inspired from Nature

2020 ◽  
Vol 13 (1) ◽  
pp. 3-15
Author(s):  
Arunachalam Vasanthanathan ◽  
Uthirakumar Siddharth ◽  
Manivannan Vignesh ◽  
Radhakrishnan Pravin
Keyword(s):  
Life Forms ◽  
Vital Role ◽  
X Ray ◽  
X Ray Imaging ◽  
Technological Growth ◽  
Evolution Of Life ◽  
Large Scope ◽  
Product Effectiveness ◽  
Water Turbines ◽  
Principle Objective

Background: Nature has always played a vital role in the evolution of life forms. The design of products in accordance with nature’s design, popularly known as biomimicry, had played a vital role in pushing the technology and product effectiveness to the next level. Humans have long sought to mimic not just the design, but also the methodology adopted by certain animals. For example, the walking technique of vertebrates has been effectively mimicked for a quadruped robot to make a system more efficient by consuming less power. Thus indirectly, nature acts as a driving factor in pushing technological growth. Methods: The principle objective of this paper is to provide an overview of popular bio mimicked products inspired by nature. This paper emphasizes a wide variety of products developed in the field of materials inspired by nature. Results: Wall-climbing robots, Sonar, X-ray imaging, Sandwich and Honeycomb structures are some of the popular products and designs inspired by nature. They have resulted in better designs, better products with improved efficiency and thus have proven to be better alternatives. Some products and designs such as Samara drone, Riblet surfaces, DSSCs, Biomimetic Drills and Water turbines have plenty of scopes to replace conventional products and designs. Conclusion: While plenty of products, structures and designs have successfully replaced older alternatives, there is still a large scope for biomimicry where it could potentially replace conventional products and designs to offer better efficiency.

scholarly journals On the relation between mini-halos and AGN feedback in clusters of galaxies

2020 ◽  
Vol 499 (2) ◽  
pp. 2934-2958
Author(s):  
A Richard-Laferrière ◽  
J Hlavacek-Larrondo ◽  
R S Nemmen ◽  
C L Rhea ◽  
G B Taylor ◽  
...  
Keyword(s):  
Large Scale ◽  
State Of The Art ◽  
Vital Role ◽  
Clusters Of Galaxies ◽  
Relativistic Jets ◽  
X Ray ◽  
Core Cluster ◽  
Central Galaxy ◽  
Central Regions ◽  
Radio Power

ABSTRACT A variety of large-scale diffuse radio structures have been identified in many clusters with the advent of new state-of-the-art facilities in radio astronomy. Among these diffuse radio structures, radio mini-halos are found in the central regions of cool core clusters. Their origin is still unknown and they are challenging to discover; less than 30 have been published to date. Based on new VLA observations, we confirmed the mini-halo in the massive strong cool core cluster PKS 0745−191 (z = 0.1028) and discovered one in the massive cool core cluster MACS J1447.4+0827 (z = 0.3755). Furthermore, using a detailed analysis of all known mini-halos, we explore the relation between mini-halos and active galactic nucleus (AGN) feedback processes from the central galaxy. We find evidence of strong, previously unknown correlations between mini-halo radio power and X-ray cavity power, and between mini-halo and the central galaxy radio power related to the relativistic jets when spectrally decomposing the AGN radio emission into a component for past outbursts and one for ongoing accretion. Overall, our study indicates that mini-halos are directly connected to the central AGN in clusters, following previous suppositions. We hypothesize that AGN feedback may be one of the dominant mechanisms giving rise to mini-halos by injecting energy into the intra-cluster medium and reaccelerating an old population of particles, while sloshing motion may drive the overall shape of mini-halos inside cold fronts. AGN feedback may therefore not only play a vital role in offsetting cooling in cool core clusters, but may also play a fundamental role in re-energizing non-thermal particles in clusters.

scholarly journals Foreign Body in abdomen

2015 ◽  
Vol 14 (2) ◽  
pp. 210-212
Author(s):  
Md Zakirul Alam ◽  
Mohibul Aziz
Keyword(s):  
Abdominal Pain ◽  
Foreign Body ◽  
Medical Science ◽  
X Ray ◽  
Diagnostic Center ◽  
History Of ◽  
Upper Abdominal ◽  
Married Female

A 19 years old married female presented with severe upper abdominal pain, repeated vomiting having history of swallowing a knife 7 months ago was admitted in Mordern Clinic and Diagnostic center, Joypurhat, Bangladesh. USG abdomen & X-ray (fig-1) abdomen were done when presence of a large foreign body (knife fig-3) in abdomen was made which latter on confirmed by Endoscopy of upper GIT (fig-2). Surprisingly the patient kept it in her abdomen for 7 months without any symptoms until the symptoms got worse and compelled her to seek medical help. The knife was removed by laparotomy, gastrotomy with uneventful recovery.Bangladesh Journal of Medical Science Vol.14(2) 2015 p.210-212

Insanity following Surgical Operations

1889 ◽  
Vol 35 (149) ◽  
pp. 1-14 ◽  
Author(s):  
C. T. Dent
Keyword(s):  
Medical Science ◽  
Surgical Operation ◽  
Additional Information ◽  
Surgical Measures ◽  
The Subject ◽  
The Mind ◽  
Surgical Operations

So far as my researches extend little attention has been paid to the subject of this paper. Yet I think it would be rash to assume that what is unrecorded is necessarily rare, even in days when so much more is put into print than any of us can either read or mark, much less digest, and when the number of writers seems in danger of exceeding the number of readers. Insanity, in some degree, as a sequela of surgical operation, though certainly rare, is, I believe, less uncommon than usually supposed, and it is chiefly in the hope of eliciting additional information from others that I venture to record my own small experience. On two subjects medical science has still an infinite deal to learn: first, the influence of disease on the mind; secondly, the influence of mind on disease. In attempting to contribute a little to the first-mentioned subject, I can really deal only with a subdivision of it, viz., the effects that may be produced on the mind by surgical measures undertaken for the relief of disease.

Introduction

Health ◽  
2019 ◽  
pp. 1-6
Author(s):  
Peter Adamson
Keyword(s):  
History Of Medicine ◽  
Medical Science ◽  
Well Being ◽  
History Of Philosophy ◽  
The Body ◽  
Central Idea ◽  
Concept Of Health ◽  
History Of ◽  
Ethical Virtue ◽  
The Mind

This introduction to the volume gives an overview of the chapters, setting out a case for integrating the history of philosophy with the history of medicine and sketching some of the key philosophical issues that arise around the concept of health. These include the difficulty of defining “health,” the mind-body relationship, and questions about how philosophy informs medical science and practice. A central idea is that the concept of health operates at two levels, the mental and the physical (or the soul and the body), so that ethical virtue and physical well-being have often been seen as parallel or mutually dependent.

5. The futures of comparative literature

2018 ◽  
pp. 113-122
Author(s):  
Ben Hutchinson
Keyword(s):  
Comparative Literature ◽  
Vital Role ◽  
Aesthetic Education ◽  
Literary Studies ◽  
Life Of The Mind ◽  
The Aesthetic ◽  
The Mind ◽  
Forms Of Knowledge

Comparative literature is both central and marginal to literary studies: central because it draws on almost every discipline in the Humanities; marginal because it is not tied to any single tradition, risking being ignored by all of them. For all its past struggles and present debates, comparative literature has an increasingly central role to play in the Humanities’ future. ‘The futures of comparative literature’ explains that in this age of specialists, generalists continue to play a vital role in shaping and supporting the life of the mind. International, interdisciplinary forms of knowledge remain the very essence of modernity. Now more than ever, the aesthetic education of comparative literature is indispensable.

Application of Carbon Nanotubes in Nanomedicine

2017 ◽  
pp. 2021-2062
Author(s):  
Omid Moradi ◽  
Hamidreza Sadegh ◽  
Ramin Shahryari-Ghoshekandi ◽  
Mehdi Norouzi
Keyword(s):  
Carbon Nanotubes ◽  
Drug Delivery ◽  
Gene Delivery ◽  
Medical Science ◽  
Vital Role ◽  
Medical Applications ◽  
Cell Penetration ◽  
Modern Life ◽  
Technological Field ◽  
History Of

Carbon Nanotubes (CNTs) have become a technological field with great potential since they can be applied in almost every aspect of modern life. One of the sectors where CNTs are expected to play a vital role is the field of medical science. This chapter focuses on the latest developments in applications of CNTs for nanomedicine. A brief history of CNTs and a general introduction to the field are presented. Then, the preparation of CNTs that makes them ideal for use in medical applications is highlighted. Examples of common applications, including cell penetration, drug delivery, and gene delivery and imaging are given. Finally, the toxicity of carbon nanotubes is discussed.

scholarly journals Comparison of Mind Control Techniques: An Assessment of Reaction Times

2016 ◽  
Vol 15 (4) ◽  
pp. 596-600
Author(s):  
Varun Malhotra ◽  
Neera Goel ◽  
Usha Dhar ◽  
Rinku Garg ◽  
Yogish Tripathi
Keyword(s):  
Reaction Time ◽  
Single Point ◽  
Medical Science ◽  
Reaction Times ◽  
Devotional Music ◽  
Mind Control ◽  
Visual Reaction ◽  
Time Test ◽  
The Mind ◽  
Reaction Time Test

Background: Every activity requires a certain amount of concentration and no effective action may be performed without deep concentration. Businessman or artists or students in school must know the art of focusing all powers of attention on a single point in order to succeed in their respective vocation.Methods: We wanted to find the best technique to increase the concentration scientifically. We thus, endeavored to study and compare the reaction times in maneuvers of anuloma viloma pranayama, kapalbhatti pranayama, gayatri chanting and exercise. Reaction time test was taken online before anuloma viloma pranayama, kapalbhatti pranayama, gayatri chanting and exercise and compared after.Results: Reaction times decreased significantly and was least during gayatri mantra. Concentration as seen by a decrease in visual reaction time denotes first a withdrawal of attention from objects of distraction and then focusing all attention upon one thing at a time. Just 30 minutes of physical activity each day offers substantial benefits to your health.Conclusions: Pranayama or devotional music chanting also decreases fatigue keeps the mind alert, and active.Bangladesh Journal of Medical Science Vol.15(4) 2016 p.596-600

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