scholarly journals Factors Contributing to Depressive Disorder among Patients with Retroviral Disease

2020 ◽  
Vol 5 (14) ◽  
pp. 83-89
Author(s):  
Nor Hidayah Jaris ◽  
Suresh Kumar Chidambaram ◽  
Mohd Razali Salleh ◽  
Salmi Razali

Major depressive disorder (MDD) increases further morbidity and mortality of patients with retroviral disease (RVD) or human immunodeficiency virus (HIV) infection. This study aimed to determine the prevalence of MDD and its contributing factors among them. Depressive symptoms were screened using the Hospital Anxiety Depression Scale (HADS), and MDD was diagnosed with the Mini International Neuropsychiatric Interview (MINI). Of the total 210 RVD patients, 27(12.9%) had MDD. The contributing factors for MDD include amphetamine-type stimulants use, social support system, and CD4 count. Interventions for RVD patients should include counselling for those abusing drugs, increasing support system and adherence to treatment.    Keywords: Retroviral Disease, Human Immunodeficiency Virus, Depression, Support system.    eISSN: 2398-4287© 2020. The Authors. Published for AMER ABRA cE-Bs by e-International Publishing House, Ltd., UK. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer-review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia.    DOI:

2021 ◽  
Vol 6 (18) ◽  
pp. 1-18
Author(s):  
Nor Hidayah Jaris ◽  
Suresh Kumar Chidambaram ◽  
Semran Kaur ◽  
Salmi Razali

Major depressive disorder (MDD) and generalized anxiety disorder (GAD) increases further morbidity and mortality of patients with retroviral disease (RVD). This study aimed to determine the prevalence and the contributing factors of MDD and GAD. The symptoms were screened using the Hospital Anxiety Depression Scale (HADS), MDD and GAD was diagnosed with the Mini International Neuropsychiatric Interview (MINI). 27(12.9%) patients had MDD and 28(13.0%) had GAD. The contributing factors include illicit drug use in the past, social support system, and CD4 count. Interventions for RVD patients should include counselling for those abusing drugs, increasing support system and adherence to treatment. Keywords: Retroviral Disease, Anxiety, Depression, Support system eISSN 2514-7528 © 2021 The Authors. Published for AMER ABRA CE-Bs by E-International Publishing House, Ltd., UK. This is an open-access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer-review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians / Africans / Arabians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia. DOI: https://doi.org/10.21834/jabs.v6i18.380


2021 ◽  
Vol 28 (1) ◽  
Author(s):  
Amany Elshabrawy Mohamed ◽  
Amira Mohamed Yousef

Abstract Background Coronavirus has affected more than 100 million people. Most of these patients are hospitalized in isolation wards or self-quarantined at home. A significant percentage of COVID-19 patients may experience psychiatric symptoms. This study attempts to assess depressive, anxiety, and post-traumatic stress symptoms in home-isolated and hospitalized COVID-19 patients, besides whether the isolation setting affected these symptoms’ presentation. Results The study involved 89 patients with confirmed COVID-19 virus, and the patients were divided into 2 groups: 43 patients in the home-isolated group (group A) and 46 patients in the hospital-isolated group (group B). The majority of subjects were male and married; also, they were highly educated. 30.2% from group A and 47.8% from group B had a medical occupation. There was a statistically significant difference (p= 0.03) between both groups in the presence of chronic disease. There was a statistically significant increase in suicidal thoughts in the home-isolated group (37.2%) (p = 0.008**). We found a statistically significant increase in the abnormal scores of Hospital Anxiety Depression Scale–Depression (HADS–Depression) in the home-isolated group (69.7%) compared to the hospital-isolated group (32.6%) (p <0.001**) which denotes considerable symptoms of depression. Moreover, we found that (32.6%) from the home-isolated group and (39.1%) from the hospital-isolated group had abnormal scores of Hospital Anxiety Depression Scale–Anxiety (HADS–Anxiety) which denotes considerable symptoms of anxiety. Also, we found 66.7% and 87.2% scored positive by the Davidson Trauma Scale (DTS) in the home-isolated group and hospital-isolated group, respectively. Which was statistically significant (p = 0.02**). On doing a binary logistic regression analysis of HADS and DTS with significantly related independent factors, we revealed that lower education levels and family history of psychiatric disorder were risk factors for abnormal HADS–Anxiety scores in COVID-19 patients. The medical occupation was a protective factor against having abnormal HADS–Depression scores in COVID-19 patients, while home isolation was a risk factor. On the contrary, the medical occupation was a risk factor for scoring positive in DTS in COVID-19 patients. Simultaneously, low levels of education and home isolation were protective factors. Conclusion A significant number of patients diagnosed with the COVID-19 virus develop depressive, anxiety, and post-traumatic stress symptoms, whether they were isolated in the hospital or at home; besides, the isolation setting may affect the presenting symptoms.


2019 ◽  
Vol 27 (2) ◽  
pp. 295-304
Author(s):  
Milana D. R. Santana ◽  
David M. Garner ◽  
Yasmim M. de Moraes ◽  
Luana B. Mangueira ◽  
Guilherme C. Alcantara ◽  
...  

2009 ◽  
Vol 27 (15_suppl) ◽  
pp. e20530-e20530
Author(s):  
D. Blum ◽  
J. Hess ◽  
A. Omlin ◽  
G. Jurt ◽  
F. Strasser ABHPM

e20530 Background: Symptom management in advanced cancer is based on appropriate and feasible syndrome staging. To test whether 1. various factors predict involuntary weight loss [WL], 2. patients [pts] attending a cachexia clinic [CC] improve nutritional intake [NI], and 3. eating-related distress [ERD] is a consequence of cachexia or psychological issues. Methods: The multidisciplinary CC (nurse, nutritionist, psycho-oncologist, palliative cancer care physician) applies standardized assessments (Symptom Visual Analogue Scales [VAS, 0=none, 10=severe], 2-day NI diary [% of calculated needs: calories, protein], secondary causes for impaired NI, weight history (2 months WL), Body Mass Index [BMI], C-reactive Protein [mg/dl, normal 8), ERD-VAS, Hospital Anxiety Depression Scale, spirituality [FICA]). Interventions include nutritional counseling, palliative cancer care and psychosocial supportive measures. Descriptive analysis, Spearman‘s Rank correlation and Factor analysis (Eigenvalue >1) were performed. Results: 58 pts (age 65 years [mean; range: 38, 85]; 28F/30M; cancer types: 24 GI, 13 GU, 12 lung/ENT, 9 other; survival 151 days [7, 776]) had 6.9% WL (-6, 22; 21%<2%), 21 kg/m2 BMI (15, 26), 52 CRP (1, 272; 32% normal), 5.6 anorexia, 1.6 anxiety, 6 HADS-A, 1.3 depression, 9 HADS-D, 68% of NI needs (1466kcal [400, 2700], 47g protein [15, 108]). WL correlated with NI kcal (r=-.29, p=.038) and protein (-.3,.035), not anorexia (.16), BMI (.032) or CRP (-.08); a 2 factor model (NI/anorexia/WL [.83/.79/.70], CRP/BMI [.86/.75] explains 67% variability. At second visit (21 days; 13, 64) 15/19 pts increased kcal (400kcal) and 15/16 protein (32g) NI, 6/17 weight. ERD correlated with anorexia (r=.56, p=.001) and depression (.48,.002), not anxiety (.23), WL (.038) or survival (-.15). A 3 factor model (ERD/anxiety/depression [.71/.85/.92], anorexia/survival [.82/.65], WL [.84]) explains 75% variability. Conclusions: A combination of clinical variables seems needed to characterize patients with involuntary WL. Most patients attending 2 consecutive cachexia clinic visits respond to multidimensional interventions. ERD seems to be associated both with loss of appetite and depression, not by WL or survival. Further testing of this intervention seems justified. [Table: see text]


2017 ◽  
Vol 1 (2) ◽  
pp. 127
Author(s):  
Jihanni Mustika Mawardani ◽  
Haryani . ◽  
Probosuseno .

ABSTRAKLatar belakang: Kemoterapi menimbulkan efek samping fi siologis dan psikologis. Gejala psikologis yang dapatterjadi berupa kecemasan dan depresi. Masalah psikososial dapat diatasi dengan memfasilitasi peningkatankoping pasien melalui pemberian informasi dan peningkatan sistem dukungan. Program PRO–SELF yangdidesain untuk pasien kanker dewasa meliputi informasi, keterampilan, dan dukungan supaya penderitakanker dapat terlibat mandiri secara efektif dan konsisten dalam mengelola efek samping kemoterapi sehinggakeparahan gejala yang berhubungan dengan penyakitnya atau penanganan penyakitnya dapat diminimalkan.Tujuan: mengetahui pengaruh implementasi Program PRO-SELF terhadap kecemasan dan depresi padapasien kemoterapi. Metode: penelitian quasi eksperimen dengan pre-test-post-test one group design yangmelibatkan 40 responden selama 3 bulan dengan kriteria inklusi semua pasien kemoterapi, berusia kurangdari 65 tahun, nilai skala Eastern Cooperative Oncology Group (ECOG) 0–2. Data dikumpulkan pada bulanJuli–September 2013 di Ruang Penyakit Dalam IRNA 1 RSUP Dr. Sardjito. Kriteria eksklusinya pasien kankeryang memiliki riwayat gangguan psikiatri. Responden diberikan pre-test, kemudian diberikan intervensi olehpeneliti berupa pemberian program PRO-SELF yang terdiri atas pemberian informasi, keterampilan tentangkemoterapi dan pengurangan efek samping kemoterapi, serta pemberian dukungan melalui telepon saatpasien di rumah. Setelah intervensi, responden diberikan post-test dengan jarak waktu 3 minggu dari pretest. Pengukuran kecemasan dan depresi menggunakan kuesioner hospital anxiety depression scale (HADS).Analisis data dilakukan dengan analisis Wilcoxon Test dengan tingkat kepercayaan 95%. Hasil: Terdapatperbedaan bermakna tingkat kecemasan pada responden (p=0,001) dari pre-test ke post-test. Tingkat depresitidak bermakna dari pre-test ke post-test (p=0,258). Kesimpulan: Implementasi program PRO-SELF secaraefektif dapat mengurangi kecemasan pasien kemoterapi, tetapi tidak dapat secara efektif mengurangi depresi.Kata Kunci: kemoterapi, kecemasan, depresi, program PRO-SELF.ABSTRACTBackground: Chemotherapy causes physiological and psychological side effects. Psychological symptomsthat can occur are anxiety and depression. Psychosocial problems can be overcame by improved patient copingthrough the provision of information and improved support system. PRO-SELF program that was designedincrease self-care skills for adult patients undergoing cancer therapy includes information, skills, and support socancer patients can be engaged effectively and consistently independent in managing side effect chemotherapy,so the severity of symptoms due to disease or treatment disease can be minimized. Objectives: To identify theeffect of implementation PRO-SELF program to anxiety and depression in chemotherapy patients. Methods:This study used pre-experimental, one-group pre-test-post-test design involving 40 respondents for 3 month,inclusion criteria in this study are all chemotherapy patients, aged less than 65 years, screening patients withEastern Cooperative Oncology Group (ECOG 0–2) scale. Data were collected within July–September 2013 inInternal Injuries IRNA 1 Room RSUP Dr. Sardjito Yogyakarta. Exclusion criteria is cancer patients who havehistory of psychiatric disorder. Respondents were given a pre-test, then were given intervention by nursingstudent with provision of information, skills in reducing chemotherapy side effects, and provide support withtelephone when patients are at home. Respondent were given post-test after intervention 3 weeks after pretest. Measurement of anxiety and depression using hospital anxiety depression scale (HADS) questionnairesand analyzed with Wilcoxon test with 95% level of signifi cancy. Results: Decrease respondents anxiety frompre-test to post-test with signifi cancy 0.001, there is signifi cant difference. Depression respondents changedfrom pre-test to post-test with signifi cancy 0.258, that is non-signifi cant difference. Discussion: PRO-SELFprogram effectively reduce anxiety because information, skills, support can reduce anxiety. Conclusions:Implementation of the PRO-SELF program effectively reduce patient anxiety chemotherapy. Yet it can notreduce depression effectively.Keywords: chemotherapy, anxiety, depression, PRO-SELF program.


Author(s):  
Andre Faro ◽  
Ludgleydson Fernandes de Araújo ◽  
Silvana Carneiro Maciel ◽  
Tiago Jessé Souza de Lima ◽  
Luana Elayne Cunha de Souza

The main objective of this study was to test the factorial structure and gender invariance of the Hospital Anxiety Depression Scale (HADS) in a non-clinical sample of 657 adolescents (Mage = 16.3 years; SD = 1.19). The research design was an instrumental investigation, based on a cross-sectional survey with a sample of adolescents in Brazil. The results presented satisfactory evidence of the validity of the factorial structure and gender invariance for the sample. The composite reliability was also satisfactory, and no problems were detected related to common method bias. The mean of the items explained variance was .31 (31 %), with a Cronbach’s Alpha at .84 for the total scale, .81 and .69 for the anxiety and depression subscales, respectively. In the discussion, we analyzed questions related to the average variance extracted of the scale, which was lower than expected. Thus, we conclude that the current findings provide validity evidence to the application of the HADS with Brazilian adolescents for clinical or research purposes.  


2020 ◽  
Vol 5 (17) ◽  
pp. 1-13
Author(s):  
Noor Melissa Nor Hadi ◽  
Fazlina Ahmad ◽  
Mohamad Rodi Isa ◽  
Salmi Razali

Caregivers of palliative cancer patients (CPCP) who are depressed put both the patients and them at risk for serious physical and psychological complications. This study investigated the prevalence of depression and its contributing factors among the CPCP in Malaysia using the diagnostic tool and validated questionnaires. About 6% of CPCPs was diagnosed to have a major depressive disorder (MDD). Coping by ‘behavioural disengagement’ increased the odds for MDD while using ‘positive reframing’ was protective for MDD. The CPCP should be trained with beneficial types of coping strategy to help them reduce the burden of caregiving and to ensure optimum mental health status. Keywords: Caregivers, Cancer, Palliative, Depression, Positive reframing, Disengagement. eISSN: 2514-7528 © 2020 The Authors. Published for AMER ABRA cE-Bs by e-International Publishing House, Ltd., UK. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by- nc-nd/4.0/). Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians) and cE-Bs (Centre for Environment- Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia. DOI: https://doi.org/10.21834/jabs.v5i17.372


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