scholarly journals Web-Based Measure of Life Events Using Computerized Life Events and Assessment Record (CLEAR): Preliminary Cross-Sectional Study of Reliability, Validity, and Association With Depression

10.2196/10675 ◽  
2019 ◽  
Vol 6 (1) ◽  
pp. e10675 ◽  
Author(s):  
Antonia Bifulco ◽  
Ruth Spence ◽  
Stephen Nunn ◽  
Lisa Kagan ◽  
Deborah Bailey-Rodriguez ◽  
...  

Background Given the criticisms of life event checklists and the costs associated with interviews, life event research requires a sophisticated but easy-to-use measure for research and clinical practice. Therefore, the Computerized Life Events and Assessment Record (CLEAR), based on the Life Events and Difficulties Schedule (LEDS), was developed. Objective The objective of our study was to test CLEAR’s reliability, validity, and association with depression. Methods CLEAR, the General Health Questionnaire, and the List of Threatening Experiences Questionnaire (LTE-Q) were completed by 328 participants (126 students; 202 matched midlife sample: 127 unaffected controls, 75 recurrent depression cases). Test-retest reliability over 3-4 weeks was examined and validity determined by comparing CLEAR with LEDS and LTE-Q. Both CLEAR and LTE-Q were examined in relation to depression. Results CLEAR demonstrated good test-retest reliability for the overall number of life events (0.89) and severe life events (.60). Long-term problems showed similar findings. In terms of validity, CLEAR severe life events had moderate sensitivity (59.1%) and specificity (65.4%) when compared with LEDS. CLEAR demonstrated moderate sensitivity (43.1%) and specificity (78.6%) when compared with LTE-Q. CLEAR severe life events and long-term problems were significantly associated with depression (odds ratio, OR 3.50, 95% CI 2.10 to 5.85, P<.001; OR 3.38, 95% CI 2.02 to 5.67, P<.001, respectively), whereas LTE-Q events were not (OR 1.06, 95% CI 0.43 to 2.60, P=.90). Conclusions CLEAR has acceptable reliability and validity and predicts depression. It, therefore, has great potential for effective use in research and clinical practice identifying stress-related factors for the onset and maintenance of depression and related disorders.


2018 ◽  
Author(s):  
Antonia Bifulco ◽  
Ruth Spence ◽  
Stephen Nunn ◽  
Lisa Kagan ◽  
Deborah Bailey-Rodriguez ◽  
...  

BACKGROUND Given the criticisms of life event checklists and the costs associated with interviews, life event research requires a sophisticated but easy-to-use measure for research and clinical practice. Therefore, the Computerized Life Events and Assessment Record (CLEAR), based on the Life Events and Difficulties Schedule (LEDS), was developed. OBJECTIVE The objective of our study was to test CLEAR’s reliability, validity, and association with depression. METHODS CLEAR, the General Health Questionnaire, and the List of Threatening Experiences Questionnaire (LTE-Q) were completed by 328 participants (126 students; 202 matched midlife sample: 127 unaffected controls, 75 recurrent depression cases). Test-retest reliability over 3-4 weeks was examined and validity determined by comparing CLEAR with LEDS and LTE-Q. Both CLEAR and LTE-Q were examined in relation to depression. RESULTS CLEAR demonstrated good test-retest reliability for the overall number of life events (0.89) and severe life events (.60). Long-term problems showed similar findings. In terms of validity, CLEAR severe life events had moderate sensitivity (59.1%) and specificity (65.4%) when compared with LEDS. CLEAR demonstrated moderate sensitivity (43.1%) and specificity (78.6%) when compared with LTE-Q. CLEAR severe life events and long-term problems were significantly associated with depression (odds ratio, OR 3.50, 95% CI 2.10 to 5.85, P<.001; OR 3.38, 95% CI 2.02 to 5.67, P<.001, respectively), whereas LTE-Q events were not (OR 1.06, 95% CI 0.43 to 2.60, P=.90). CONCLUSIONS CLEAR has acceptable reliability and validity and predicts depression. It, therefore, has great potential for effective use in research and clinical practice identifying stress-related factors for the onset and maintenance of depression and related disorders.



1989 ◽  
Vol 16 (1) ◽  
pp. 77-91 ◽  
Author(s):  
Hans-Ulrich Wittchen ◽  
Cecilia Ahmoi Essau ◽  
Heidemarie Hecht ◽  
Wolfgang Teder ◽  
Hildegard Pfister




1993 ◽  
Vol 162 (S19) ◽  
pp. 25-29 ◽  
Author(s):  
Graham Thornicroft ◽  
Christopher Gooch ◽  
Catherine O'Driscoll ◽  
Sawsan Reda

The development of the hospital and community versions of the Patient Attitude Questionnaire is described. The instrument rates the attitudes of psychiatric patients towards their treatment settings and staff, and is framed specifically to assess attitudinal change during the transfer of patients from hospital. For the items rated using the kappa coefficient of agreement, the mean test-retest reliability value was 0.51, and the average inter-rater value was 0.82. This study shows that long-term psychiatric patients are able to give clear and consistent views about their living arrangements - views that should be sought and respected by staff.



2000 ◽  
Vol 87 (3) ◽  
pp. 750-752 ◽  
Author(s):  
J. E. Hovens ◽  
I. Bramsen ◽  
H. M. van der Ploeg ◽  
I. E. W. Reuling

Three groups of first-year male and female medical students (total N = 90) completed the Trauma and Life Events Self-report Inventory twice. Test-retest reliability for the three different time periods was .82, .89, and .75, respectively.



NeuroImage ◽  
2006 ◽  
Vol 29 (3) ◽  
pp. 1000-1006 ◽  
Author(s):  
Adam R. Aron ◽  
Mark A. Gluck ◽  
Russell A. Poldrack


2015 ◽  
Vol 126 (2) ◽  
pp. 356-364 ◽  
Author(s):  
U. Hofstadt-van Oy ◽  
P.M. Keune ◽  
J. Muenssinger ◽  
D. Hagenburger ◽  
P. Oschmann


2015 ◽  
Vol 35 (7) ◽  
pp. 1199-1205 ◽  
Author(s):  
Kati Alakurtti ◽  
Jarkko J Johansson ◽  
Juho Joutsa ◽  
Matti Laine ◽  
Lars Bäckman ◽  
...  

We measured the long-term test–retest reliability of [11C]raclopride binding in striatal subregions, the thalamus and the cortex using the bolus-plus-infusion method and a high-resolution positron emission scanner. Seven healthy male volunteers underwent two positron emission tomography (PET) [11C]raclopride assessments, with a 5-week retest interval. D2/3 receptor availability was quantified as binding potential using the simplified reference tissue model. Absolute variability (VAR) and intraclass correlation coefficient (ICC) values indicated very good reproducibility for the striatum and were 4.5%/0.82, 3.9%/0.83, and 3.9%/0.82, for the caudate nucleus, putamen, and ventral striatum, respectively. Thalamic reliability was also very good, with VAR of 3.7% and ICC of 0.92. Test-retest data for cortical areas showed good to moderate reproducibility (6.1% to 13.1%). Our results are in line with previous test–retest studies of [11C]raclopride binding in the striatum. A novel finding is the relatively low variability of [11C]raclopride binding, providing suggestive evidence that extrastriatal D2/3 binding can be studied in vivo with [11C]raclopride PET to be verified in future studies.





2013 ◽  
Vol 89 (1) ◽  
pp. 106-114 ◽  
Author(s):  
Jan Ferenc Brunner ◽  
Tor Ivar Hansen ◽  
Alexander Olsen ◽  
Toril Skandsen ◽  
Asta Håberg ◽  
...  


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