scholarly journals Chemotherapy-induced peripheral neuropathy detection via smartphone app: a cross-sectional pilot study (Preprint)

10.2196/27502 ◽  
2021 ◽  
Author(s):  
Ciao-Sin Chen ◽  
Judy Kim ◽  
Harsha Guntupalli ◽  
Noemi Garg ◽  
Reshma Jagsi ◽  
...  
Keyword(s):  
Peripheral Neuropathy ◽  
Pilot Study ◽  
Smartphone App ◽  
Cross Sectional

scholarly journals Chemotherapy-induced peripheral neuropathy detection via smartphone app in a cross-sectional pilot study (Preprint)

2021 ◽  
Author(s):  
Ciao-Sin Chen ◽  
Judy Kim ◽  
Harsha Guntupalli ◽  
Noemi Garg ◽  
Reshma Jagsi ◽  
...  
Keyword(s):  
Peripheral Neuropathy ◽  
Pilot Study ◽  
Clinical Care ◽  
Objective Assessment ◽  
Self Report ◽  
Smartphone App ◽  
Cross Sectional ◽  
Patient Reported ◽  
Functional Assessments ◽  
Hands And Feet

BACKGROUND Severe chemotherapy-induced peripheral neuropathy (CIPN) can cause long-term dysfunction of the hands and feet, interfere with activities of daily living, and diminish quality of life. Monitoring to identify CIPN before it progresses to life-altering severity relies on patients self-reporting subjective symptoms to their clinical team. Objective assessment is not a standard component of CIPN monitoring due to the requirement for specially trained healthcare professionals and equipment. Smartphone apps have the potential to conveniently collect both subjective and objective CIPN data directly from patients, which could improve CIPN monitoring. OBJECTIVE The objective of this cross-sectional pilot study was to assess the feasibility of functional CIPN assessment via smartphone app. METHODS Twenty-six patients who had completed neurotoxic chemotherapy were enrolled and classified as CIPN cases (n=16) or controls (n=10) based on self-report symptoms. All participants completed CIPN assessments within the NeuroDetect app a single time including patient-reported surveys (CIPN20 and PRO-CTCAE) and functional assessments (Gait and Balance and 9 Hole Peg Test). RESULTS Exploratory comparisons between CIPN cases and controls indicate CIPN cases had shorter step length (P=.003), unique swaying acceleration patterns during a walking task, and shorter hand moving distance during a manual dexterity task. CONCLUSIONS Our results confirm that remote CIPN assessment via a smartphone app is feasible and suggest that functional data may be indicative of CIPN manifestations in the hands and feet. Additional work is needed to determine which functional assessments are most indicative of CIPN and could be used for CIPN monitoring within clinical care.

Depression, sleeping pattern, and suicidal ideation among medical students in Bangladesh: a cross-sectional pilot study

2020 ◽  
Author(s):  
M. Tasdik Hasan ◽  
Sahadat Hossain ◽  
Rajat Das Gupta ◽  
Vivek Podder ◽  
Naima Afroz Mowri ◽  
...  
Keyword(s):  
Medical Students ◽  
Pilot Study ◽  
Suicidal Ideation ◽  
Cross Sectional

A pilot study of attachment relationships, psychological problems and negative automatic thoughts among college students in Pakistan

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Siddrah Irfan ◽  
Nor Sheereen Zulkefly
Keyword(s):  
Pilot Study ◽  
Cross Sectional Study ◽  
Psychological Problems ◽  
Peer Attachment ◽  
Automatic Thoughts ◽  
Cross Sectional ◽  
Attachment Relationships ◽  
Automatic Thought ◽  
Symptoms Of Depression ◽  
Negative Automatic Thoughts

AbstractObjectivesThe present pilot study examined the associations between attachment relationships, psychological problems, and negative automatic thoughts among late adolescents in Rawalpindi, Pakistan.SubjectsA total of 98 participants (male = 49, female = 49) were recruited from government colleges in Rawalpindi, Pakistan.MethodsThe measures used to assess the research variables of this cross sectional study were the Inventory of Parent-Peer Attachment (IPPA-Urdu), Depression, Anxiety, and Stress Scale (DASS-Urdu), and the Automatic Thought Questionnaire (ATQ-Urdu).ResultsAll of these measures had good reliabilities. Findings of the correlation analyses demonstrated that maternal, paternal and peer attachment relationships were negatively related to symptoms of depression and anxiety as well as to negative automatic thoughts. On the other hand, depressive and anxiety symptoms were positively associated with negative automatic thoughts. Additionally, findings suggested that future studies must investigate adolescents from two-parent households and exclude those with only one living parent.ConclusionThe results underscored the need for further investigations of the linkages between attachment relationships, negative automatic thoughts and psychological problems on larger samples.

scholarly journals Chemotherapy-induced peripheral neuropathy: longitudinal analysis of predictors for postural control

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Jana Müller ◽  
Charlotte Kreutz ◽  
Steffen Ringhof ◽  
Maximilian Koeppel ◽  
Nikolaus Kleindienst ◽  
...  
Keyword(s):  
Peripheral Neuropathy ◽  
Peripheral Nerve ◽  
Postural Control ◽  
Action Potentials ◽  
Exercise Intervention ◽  
Cross Sectional Study ◽  
Nerve Function ◽  
Cross Sectional ◽  
Peripheral Nerve Function

AbstractImpaired postural control is often observed in response to neurotoxic chemotherapy. However, potential explanatory factors other than chemotherapy-induced peripheral neuropathy (CIPN) have not been adequately considered to date due to primarily cross-sectional study designs. Our objective was to comprehensively analyze postural control during and after neurotoxic chemotherapy, and to identify potential CIPN-independent predictors for its impairment. Postural control and CIPN symptoms (EORTC QLQ-CIPN20) were longitudinally assessed before, during and three weeks after neurotoxic chemotherapy, and in three and six months follow-up examinations (N = 54). The influence of peripheral nerve function as determined by nerve conduction studies (NCS: compound motor action potentials (CMAP) and sensory action potentials (SNAP)), physical activity, and muscle strength on the change in postural control during and after chemotherapy was analyzed by multiple linear regression adjusted for age and body mass index. Postural control, CIPN signs/symptoms, and CMAP/SNAP amplitudes significantly deteriorated during chemotherapy (p < .01). During follow-up, patients recovered from postural instabilities (p < .01), whereas CIPN signs/symptoms and pathologic NCS findings persisted compared to baseline (p < .001). The regression model showed that low CMAP and high SNAP amplitudes at baseline predicted impairment of postural control during but not after chemotherapy. Hence, pre-therapeutically disturbed somatosensory inputs may induce adaptive processes that have compensatory effects and allow recovery of postural control while CIPN signs/symptoms and pathologic peripheral nerve function persist. Baseline NCS findings in cancer patients who receive neurotoxic chemotherapy thus might assist in delineating individual CIPN risk profiles more precisely to which specific exercise intervention programs could be tailor-made.

scholarly journals A Cross-Sectional Pilot Study of Blood Utilization in 27 Hospitals in Northern California

2014 ◽  
Vol 142 (4) ◽  
pp. 498-505 ◽  
Author(s):  
Evan M. Bloch ◽  
Claudia Cohn ◽  
Roberta Bruhn ◽  
Nora Hirschler ◽  
Kim-anh Nguyen
Keyword(s):  
Pilot Study ◽  
Northern California ◽  
Cross Sectional ◽  
Blood Utilization

Self-Care Practices Among Adult Type 2 Diabetes Patients With and Without Peripheral Neuropathy: A Cross-Sectional Study at Tertiary Healthcare Settings in Ethiopia

2021 ◽  
pp. 084456212110206
Author(s):  
Mezgebu Gode ◽  
Fekadu Aga ◽  
Aklil Hailu
Keyword(s):  
Social Support ◽  
Peripheral Neuropathy ◽  
Self Care ◽  
Cross Sectional Study ◽  
Care Practice ◽  
Cross Sectional ◽  
Glucose Testing ◽  
Blood Glucose Testing ◽  
Care Practices

Background Type 2 diabetes mellitus (T2D) has become a global health challenge. Diabetic peripheral neuropathy (DPN) is one of the common comorbidities of T2D that may affect the ability to perform diabetes self-care. Purpose To compare self-care practices between adult T2D patients with and without comorbid DPN and identify factors predicting self-care practices. Methods In this cross-sectional study, conducted at tertiary hospitals in Ethiopia, a total of 216 (108 with DNP and 108 without DNP) participants completed an interviewer-administered questionnaire including measures of diabetes self-care practices, self-evaluated peripheral neuropathy, self-efficacy, diabetes knowledge, and social support. Results Adult T2D patients with comorbid DPN had lower dietary (P< 0.001), exercise (P< 0.001), blood glucose testing (P = 0.001), and foot (P = 0.007) self-care practice than those without DPN. Social support is a significant predictor of dietary self-care in both groups while predicting foot self-care and blood glucose testing in those with comorbid DPN. Moreover, occupation, education, and having a glucometer are significant predictors of diabetes self-care practice in both groups. Conclusion This study found that adult T2D patients with comorbid DPN have poorer diabetes self-care practice than those without comorbid DPN. Interventions should focus on addressing social support and access to a glucometer in order to improve diabetes self-care practices in adult T2D patients with comorbid DPN.

scholarly journals Knowledge, Attitudes, Behaviors of Women Related to Pregnancy, and Early Childhood Caries Prevention: A Cross-Sectional Pilot Study

2021 ◽  
Vol 12 ◽  
pp. 215013272110133
Author(s):  
Neel Shimpi ◽  
Ingrid Glurich ◽  
Catherine Maybury ◽  
Min Qi Wang ◽  
Kazumasa Hashimoto ◽  
...  
Keyword(s):  
Oral Health ◽  
Pilot Study ◽  
Health Education ◽  
Survey Study ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Health Maintenance ◽  
Significance Level ◽  
Study Results ◽  
And Behaviors

Objective Health education interventions during pregnancy can influence maternal oral health (OH), maternal OH-behaviors and children’s OH. Interventions that can be delivered at anytime and anywhere, for example mobile-health (mHealth) provides an opportunity to address challenges of health education and support activation of women in underserved and rural communities to modify their health behavior. This pilot study was undertaken as a part of a mHealth initiative to determine knowledge, attitudes, and behaviors related to pregnancy and ECC prevention among women attending obstetrics/gynecology (OB/GYN) practices at a large rurally-based clinic. Methods A cross-sectional survey study was voluntarily engaged by women (n = 191) aged 18 to 59 years attending OB/GYN visits, over a 3-week period from 12/2019 to 1/2020. Survey results were analyzed applying descriptive statistics, X2 and Fisher’s Exact tests. The significance level was set at P < .0001 for all analyses. Results Approximately half of respondents were between 18 and 29 years (53%), had a college degree (55%), and 100% reported cell phone use. Whereas 53% and 31%, respectively, indicated that they were “somewhat” or “very” sure of how to prevent ECC in their children, only 9% recognized evidence of early decay and 30% did not know the purpose of fluoride. Overall, only 27% of participants correctly answered the knowledge-based questions. Further, only 57% reported their provider explained things in a way that was easy to understand. Only 24% reported seeing a dentist during their current pregnancy. Conclusions Study results suggested potential gaps in knowledge and behaviors related to ECC prevention and provided baseline data to inform future interventions to improve ECC prevention practices. Notably, majority of participants used their cell phones for making medical/dental appointments and reported using their phones to look up health-related information. This demographic represents a potentially receptive target for mHealth approaches to improve understanding of oral health maintenance during pregnancy and ECC prevention.

scholarly journals Trimethylamine N-Oxide, a Gut Microbiota-Derived Metabolite, Is Associated with Cardiovascular Risk in Psoriasis: A Cross-Sectional Pilot Study

2021 ◽  
Author(s):  
Mariusz Sikora ◽  
Norbert Kiss ◽  
Albert Stec ◽  
Joanna Giebultowicz ◽  
Emilia Samborowska ◽  
...  
Keyword(s):  
Cardiovascular Risk ◽  
Pilot Study ◽  
Gut Microbiota ◽  
Cross Sectional

Perceptions and Understanding of Diabetes Mellitus Technology in Adults with Type 1 or Type 2 DM: A Pilot Survey from Pakistan

2021 ◽  
pp. 193229682110111
Author(s):  
Sarah Nadeem ◽  
Uswah Siddiqi ◽  
Russell Seth Martins ◽  
Kaleemullah Badini
Keyword(s):  
Diabetes Mellitus ◽  
Pilot Study ◽  
Diabetes Care ◽  
Online Survey ◽  
Small Sample Size ◽  
Developed Countries ◽  
Small Sample ◽  
Cost Of Care ◽  
Cross Sectional ◽  
Specific Patient

Introduction: Diabetes mellitus technology (DMT) is increasingly used for routine management in developed countries, yet its uptake in developing countries is not as consistent. Multiple factors may influence this, including country specific patient perception regarding DMT. We conducted a pilot study in Pakistan to understand this important question which has not been studied yet. Methods: A cross-sectional pilot study was conducted in Pakistan. An anonymous survey exploring perceptions of diabetes technology was circulated on social media platforms, collecting responses over 2 weeks. Target population included adults (≥18 years) living in Pakistan, with DM1 or 2. Results: A total of 40 responses were received. The majority (36/40) reported using conventional glucometers. Nine used continuous glucose monitoring (CGM). Thirty-two of 40 patients believed DMT improved diabetes care, 22 felt it helped decreased risk of Diabetes-related complications. 15/40 stated that DMT results in increased cost of care. Sixteen reported their diabetes care teams had never discussed wearable DMT options whereas 11 disliked them because they did not want a device on their self. Conclusion: In our pilot study we have identified broad themes of opportunity and challenges to DMT use in Pakistan. Patients’ perceptions regarding DMT were generally positive but significant barriers to its acceptance included high cost, lack of discussion between doctor and patient about available technology and personal hesitation. Limitations of our study include sampling bias (online survey) and small sample size, but this data can help inform larger studies, to look at this important topic in greater detail.

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