scholarly journals Supporting the Medication Adherence of Older Mexican Adults Through External Cues Provided With Ambient Displays: Feasibility Randomized Controlled Trial (Preprint)

2019 ◽  
Author(s):  
Ernesto Zárate-Bravo ◽  
Juan-Pablo García-Vázquez ◽  
Engracia Torres-Cervantes ◽  
Gisela Ponce ◽  
Ángel G Andrade ◽  
...  

BACKGROUND Problems with prospective memory, which refers to the ability to remember future intentions, cause deficits in basic and instrumental activities of daily living, such as taking medications. Older adults show minimal deficits when they rely on mostly preserved and relatively automatic associative retrieval processes. On the basis of this, we propose to provide external cues to support the automatic retrieval of an intended action, that is, to take medicines. To reach this end, we developed the Medication Ambient Display (MAD), a system that unobtrusively presents relevant information (unless it requires the users’ attention) and uses different abstract modalities to provide external cues that enable older adults to easily take their medications on time and be aware of their medication adherence. OBJECTIVE This study aimed to assess the adoption and effect of external cues provided through ambient displays on medication adherence in older adults. METHODS A total of 16 older adults, who took at least three medications and had mild cognitive impairment, participated in the study. We conducted a 12-week feasibility study in which we used a mixed methods approach to collect qualitative and quantitative evidence. The study included baseline, intervention, and postintervention phases. Half of the participants were randomly allocated to the treatment group (n=8), and the other half was assigned to the control group (n=8). During the study phases, research assistants measured medication adherence weekly through the pill counting technique. RESULTS The treatment group improved their adherence behavior from 80.9% at baseline to 95.97% using the MAD in the intervention phase. This decreased to 76.71% in the postintervention phase when the MAD was no longer being used. Using a one-way repeated measures analysis of variance and a post hoc analysis using the Tukey honestly significant difference test, we identified a significant statistical difference between the preintervention and intervention phases (<i>P</i>=.02) and between the intervention and postintervention phases (<i>P</i>=.002). In addition, the medication adherence rate of the treatment group (95.97%) was greater than that of the control group (88.18%) during the intervention phase. Our qualitative results showed that the most useful cues were the auditory reminders, followed by the stylized representations of medication adherence. We also found that the MAD’s external cues not only improved older adults’ medication adherence but also mediated family caregivers’ involvement. CONCLUSIONS The findings of this study demonstrate that using ambient modalities for implementing external cues is useful for drawing the attention of older adults to remind them to take medications and to provide immediate awareness on adherence behavior. CLINICALTRIAL ClinicalTrials.gov NCT04289246; https://tinyurl.com/ufjcz97

10.2196/14680 ◽  
2020 ◽  
Vol 8 (3) ◽  
pp. e14680
Author(s):  
Ernesto Zárate-Bravo ◽  
Juan-Pablo García-Vázquez ◽  
Engracia Torres-Cervantes ◽  
Gisela Ponce ◽  
Ángel G Andrade ◽  
...  

Background Problems with prospective memory, which refers to the ability to remember future intentions, cause deficits in basic and instrumental activities of daily living, such as taking medications. Older adults show minimal deficits when they rely on mostly preserved and relatively automatic associative retrieval processes. On the basis of this, we propose to provide external cues to support the automatic retrieval of an intended action, that is, to take medicines. To reach this end, we developed the Medication Ambient Display (MAD), a system that unobtrusively presents relevant information (unless it requires the users’ attention) and uses different abstract modalities to provide external cues that enable older adults to easily take their medications on time and be aware of their medication adherence. Objective This study aimed to assess the adoption and effect of external cues provided through ambient displays on medication adherence in older adults. Methods A total of 16 older adults, who took at least three medications and had mild cognitive impairment, participated in the study. We conducted a 12-week feasibility study in which we used a mixed methods approach to collect qualitative and quantitative evidence. The study included baseline, intervention, and postintervention phases. Half of the participants were randomly allocated to the treatment group (n=8), and the other half was assigned to the control group (n=8). During the study phases, research assistants measured medication adherence weekly through the pill counting technique. Results The treatment group improved their adherence behavior from 80.9% at baseline to 95.97% using the MAD in the intervention phase. This decreased to 76.71% in the postintervention phase when the MAD was no longer being used. Using a one-way repeated measures analysis of variance and a post hoc analysis using the Tukey honestly significant difference test, we identified a significant statistical difference between the preintervention and intervention phases (P=.02) and between the intervention and postintervention phases (P=.002). In addition, the medication adherence rate of the treatment group (95.97%) was greater than that of the control group (88.18%) during the intervention phase. Our qualitative results showed that the most useful cues were the auditory reminders, followed by the stylized representations of medication adherence. We also found that the MAD’s external cues not only improved older adults’ medication adherence but also mediated family caregivers’ involvement. Conclusions The findings of this study demonstrate that using ambient modalities for implementing external cues is useful for drawing the attention of older adults to remind them to take medications and to provide immediate awareness on adherence behavior. Trial Registration ClinicalTrials.gov NCT04289246; https://tinyurl.com/ufjcz97


1994 ◽  
Vol 79 (1) ◽  
pp. 191-194 ◽  
Author(s):  
Edgar F. Pierce ◽  
Donald W. Pate

Limited research indicates positive affective change following acute bouts of exercise, but whether this improved affect among younger subjects may be generalized to older individuals is not known. The present study, then, examined the effects of a single bout of physical activity among older participants. 16 trained women ( Moge = 64.5 ± 7.6 yr.) completed an abbreviated Profile of Mood States prior to and immediately following a 75-min. session of aerobic line dancing. A series of one-way analyses of variance with repeated measures were used to examine differences between pre- and posttest subscores on mood states. Significant decreases following exercise in scores on Tension, Depression, Fatigue, and Anger and a significant increase in scores on Vigor relative to preexercise (control) scores were found. Global mood was significantly improved after the exercise session. No significant difference was found between pre- and postexercise measures of Confusion. Previous findings of significant improvements in affect immediately after an acute bout of exercise may be generalized to older adults. Repetition with a nonexercised control group is desirable.


2020 ◽  
Vol 5 (4) ◽  
pp. 44
Author(s):  
Faiza A. Abou-El-Soud ◽  
Helalia Shalabi Mohamed

Purpose: This study was aimed to measure the impact of self-efficacy theory to improve medication adherence among older adults’ patients with glaucoma. Methodology: A quasi-experimental design was used to investigate the study hypotheses.  Study Sample: A total of 284 older adults with glaucoma were screened to select non-adherent patients with medication. The recruited study sample was (152) who are non-adherent with glaucoma medication divided equally into (76 study group) and (76 control group). Setting: the study was conducted at the outpatient clinics of Ophthalmology at University Hospital, Shebin El-Kom, Egypt.  Tools: three tools were used for the purpose of data collection (I) Bio-socio-demographic characteristics questionnaire; (II) Medication Adherence Rating Scale (III) Glaucoma Medication Self-Efficacy Scale. Findings: The findings revealed that the mean age of the studied sample was 74.86+4.63 (non-adherent to medication). Patients age and presence of more than three multiple chronic illnesses with poly-medications are the highest risk factors of adherence to medications (OR = 10.9; 95% CI 6.8 -16.32, P = 0.000); (OR = 12.6; 95% CI 8.2 -18.4, P = 0.000) and (OR = 13.2; 95% CI 7.4 -19.8, P = 0.000) respectively. Participants who received the intervention program showed a significant improvement in their self-efficacy in overcoming medication adherence barriers compared to the control group. An improvement of the self-efficacy in their ability in carrying out glaucoma medication correctly compared to the control group was shown by highly statistically significant differences between total mean scores at (t =3.426, P =.001; t =17.174, P=.000; t =18.141, P=.000) respectively. The intervention program of glaucoma medication management had a positive impact on the patients’ outcomes compared to the control group. There is a statistically significant difference between patients’ feelings and thoughts pre and post-intervention was detected. Unique contribution to theory, practice and policy: The findings confirm the effectiveness of an intervention/educational program based on self-efficacy theory in terms of improving glaucoma medication adherence among older adults. Glaucoma’s medication principles should be discussed at regular intervals based on patients' needs and the barriers they are facing.


2021 ◽  
Vol 33 (S1) ◽  
pp. 48-48
Author(s):  
C. Noriega ◽  
G. Pérez-Rojo ◽  
J. López ◽  
C. Velasco ◽  
M.I. Carretero ◽  
...  

IntroductionKayser-Jones (1981) described infantilization as one of the four most frequent types of violence in nursing homes. Older people perceive infantilization as disrespectful and patronizing. In professionals, it can lead to protective behaviors that reduce autonomy and generate more dependency. Despite the importance of this phenomenon, the interventions are scarce and show methodological limitations.ObjectiveThis study analyzed the efficacy of a psychoeducation program for the prevention of infantilization in professionals working in nursing homes. The sample included 154 direct-care workers. The experimental group (N=111) attended a psychoeducational group intervention program while the control group (N=43) did not attend any intervention program. We assessed the infantilized practices the professionals recognized they conducted and the ones observed in the institution before and after the intervention. The intervention lasted 6 hours and included four sessions distributed in two days. These sessions aimed to reduce negative stereotypes, preventing infantilized communication patterns and the use of behaviors or practices that are frequently used with children. We also offered professionals alternative practices that recognize autonomy, decision-making and respect older adults´ dignity and uniqueness. To analyze data, we conducted Repeated measures of ANOVA and one-way ANCOVAs.Results:The scores of infantilization in the experimental group significantly decreased from pre-intervention to post-intervention in the professional, F(1, 85) = 37.184, p = .01, partial η2 = .030, and in the institution, F(1, 84) = 32.128, p = .01, partial η2 = .277, while the control group did not show any changes. There was a statistically significant difference in post-intervention between the experimental and the control group when participants scored their infantilization practices, F(1, 115) = 5.175, p = .03, partial η2 = .043, and infantilization practices observed in the institution, F(1, 115) = 5.810, p = .018, partial η2 = .048.Conclusion:These results reflect the importance of developing interventions focused on preventing infantilization, methodologically rigorous, in which professionals´ training and education are considered key pieces to generate a culture of change. More research is needed to understand this problem in greater depth to develop programs that address this problem at different levels.Funding:This research was funded by the Spanish Ministry of Economy and Competitiveness (grant no. PSI2016-79803-R).


2020 ◽  
pp. 1-11
Author(s):  
Iraida Delhom ◽  
Encarnación Satorres ◽  
Juan C. Meléndez

Abstract Objectives: Emotional intelligence (EI) is a strong predictor of negative mood. Applying emotional skills correctly can help to increase positive emotional states and reduce negative ones. This study aims to implement EI intervention designed to improve clarity, repair EI dimensions and coping strategies, and reduce negative mood in older adults. Design: Participants were randomly assigned to the treatment or control group. Setting: Participants were evaluated individually before and after the intervention. Participants: Participants included 111 healthy older adults; 51 in the treatment group and 60 in the control group. Intervention: An EI program was implemented. The program was administered over 10 sessions lasting 90 min each. Measurements: EI dimension (attention, clarity, and repair), coping strategies, hopelessness, and mood were assessed. Results: Analysis of variance for repeated measures was applied. In the treatment group, scores on clarity and emotional repair increased and attention to emotions decreased; problem-focused coping (problem-solving, positive reappraisal, and seeking social support) showed significant increases, whereas emotion-focused coping (negative self-focused and overt emotional expression) obtained significant decreases; scores on negative mood measures declined significantly. Conclusions: An intervention based on EI is effective in older adults. After the EI intervention, the participants showed significant increases in their levels of clarity and emotional repair and intermediate levels of attention. In addition, the intervention was found to influence adaptation results, increasing the use of adaptive coping strategies and decreasing the use of maladaptive strategies, as well as reducing hopelessness and depressive symptoms.


2019 ◽  
Vol 11 (8) ◽  
pp. 1
Author(s):  
Joy I. Anyanwu ◽  
Oliver Rotachukwu Ngwoke ◽  
Vera Victor-Aigbodion ◽  
Ogechi Nnamani ◽  
Bartholomew C. Nwefuru

OBJECTIVE: This research aimed to determine the effect of yoga therapy in managing low back pain (LBP) among older adults. METHOD: 40 participants who were having low back pain were assessed. All participants completed baseline evaluation before beginning the Yoga intervention and at 6, 12 and 18 weeks. Participants completed a questionnaire titled Oswestry Low Back Pain Disability Questionnaire (ODQ). The statistical tool used for data analysis was within-and-between subjects ANOVA. RESULTS: The finding showed no significant difference in the baseline assessment for LBP between the treatment group and the waitlisted control group, F(1,38) = 2.697, P=.000, &eta;2 = .066. The posttest assessment at 6th week revealed a significant reduction of LBP among older adults in the yoga treatment group compared with those in the waitlisted control group, F(1,37) = 3209.376, P = .000, &eta;2 = .989. The assessment at 12th week revealed significant reduction in LBP among older adult in the yoga treatment group compared with those in the waitlisted control group, F(1,36) = 2389.154, P = .000, &eta;2 = .985. The assessment at 18th week further revealed a significant reduction in LBP among older adult in the yoga treatment group compared with those in the waitlisted control group, F(1,36) = 2775.162, P = .000, &eta;2 = .987. CONCLUSION: Yoga therapy is an effective intervention for managing low back pain among older adults. Thus, gerontology counsellors can provide help to older people with low back pain within the framework of Yoga therapy. Further studies are required to find out and corroborate the efficacy of Yoga Therapy in managing low back pain among older adults.


2011 ◽  
Vol 39 (10) ◽  
pp. 1431-1439 ◽  
Author(s):  
Selcuk Karaman

The effects of audience response systems (ARS) on students' academic success and their perceptions of ARS were examined in this study. Participants, comprising 44 undergraduate students, were randomly assigned to a control or treatment group. The course design was the same for both groups and the instructor prepared the multiple-choice questions in advance; students in the control group responded to these questions verbally whereas the treatment group used ARS. Two paper-based examinations were used to measure the learning of concepts and skills that were taught. Students' perceptions of ARS were collected via a questionnaire. Results showed that ARS usage has a significant learning achievement effect in the first 4 weeks but not at the end of the second 4 weeks. There was no significant difference in retention between either group. Students perceived the ARS tool positively, finding it very enjoyable and useful.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Kyoungwon Baik ◽  
Seon Myeong Kim ◽  
Jin Ho Jung ◽  
Yang Hyun Lee ◽  
Seok Jong Chung ◽  
...  

AbstractWe investigated the efficacy of donepezil for mild cognitive impairment in Parkinson’s disease (PD-MCI). This was a prospective, non-randomized, open-label, two-arm study. Eighty PD-MCI patients were assigned to either a treatment or control group. The treatment group received donepezil for 48 weeks. The primary outcome measures were the Korean version of Mini-Mental State Exam and Montreal Cognitive Assessment scores. Secondary outcome measures were the Clinical Dementia Rating, Unified Parkinson’s Disease Rating Scale part III, Clinical Global Impression scores. Progression of dementia was assessed at 48-week. Comprehensive neuropsychological tests and electroencephalography (EEG) were performed at baseline and after 48 weeks. The spectral power ratio of the theta to beta2 band (TB2R) in the electroencephalogram was analyzed. There was no significant difference in the primary and secondary outcome measures between the two groups. However, the treatment group showed a significant decrease in TB2R at bilateral frontotemporoparietal channels compared to the control group. Although we could not demonstrate improvements in the cognitive functions, donepezil treatment had a modulatory effect on the EEG in PD-MCI patients. EEG might be a sensitive biomarker for detecting changes in PD-MCI after donepezil treatment.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Ferdiye Küçük ◽  
Sibel Yıldırım ◽  
Serap Çetiner

Abstract Background The purpose of this study was to assess the cytotoxicity of various concentrations of ozonated water (OW) on human primary dental pulp cells. Methods Human primary dental pulp cells were isolated from exfoliated primary canine teeth of an 11-year-old patient with good systemic and oral health. Afterwards, cells were divided into 6 experimental groups; four groups of OW in concentrations of 2 mg/L, 4 mg/L, 8 mg/L, and 16 mg/L, untreated control group, and cell culture without cells. Cytotoxicity was evaluated after exposure for 5-min exposure using Mosmann’s Tetrazolium Toxicity (MTT) assay at 0 h and 48 h time points. Data were analyzed using a repeated measures analysis of variance and Post-hoc tests were performed using Bonferroni correction for multiple comparisons. Results All experimental groups showed proliferation at 0 h time point. However, all groups also experienced a decrease in overtime at 48 h time point (p < 0.05). At both time points 2 mg/L OW showed the highest cell viability as well as proliferation. At 0 h time point, the increase in cell viability for all experimental groups was found statistically significant when compared to positive control group (p < 0.05). At 48 h time point, although 8 mg/L and 16 mg/L OW showed statistically significant reduction in compare to 0 h time point, 2 mg/L and 4 mg/L OW groups didn’t experience any statistically significant difference (p < 0.05). Conclusion Considering our findings, due to ozonated water's induced a higher proliferation rate of dental pulp cells, indicating their biocompatibility and a possible adjuvant on irrigating agent in regenerative endodontic procedures.


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