scholarly journals Use of Artificial Intelligence as a Predictor of the Response to Treatment in Alopecia Areata (Preprint)

2021 ◽  
Author(s):  
Fernando Alarcón-Soldevilla ◽  
Francisco José Hernández-Gómez ◽  
Juan Antonio García-Carmona ◽  
Celia Campoy Carreño ◽  
Ramon Grimalt ◽  
...  

BACKGROUND Artificial intelligence (AI) has emerged in dermatology with some studies focusing on skin disorders such as skin cancer, atopic dermatitis, psoriasis, and onychomycosis. Alopecia areata (AA) is a dermatological disease whose prevalence is 0.7%-3% in the United States, and is characterized by oval areas of nonscarring hair loss of the scalp or body without evident clinical variables to predict its response to the treatment. Nonetheless, some studies suggest a predictive value of trichoscopic features in the evaluation of treatment responses. Assuming that black dots, broken hairs, exclamation marks, and tapered hairs are markers of negative predictive value of the treatment response, while yellow dots are markers of no response to treatment according to recent studies, the absence of these trichoscopic features could indicate favorable disease evolution without treatment or even predict its response. Nonetheless, no studies have reportedly evaluated the role of AI in AA on the basis of trichoscopic features. OBJECTIVE This study aimed to develop an AI algorithm to predict, using trichoscopic images, those patients diagnosed with AA with a better disease evolution. METHODS In total, 80 trichoscopic images were included and classified in those with or without features of negative prognosis. Using a data augmentation technique, they were multiplied to 179 images to train an AI algorithm, as previously carried out with dermoscopic images of skin tumors with a favorable response. Subsequently, 82 new images of AA were presented to the algorithm, and the algorithm classified these patients as responders and non-responders; this process was reviewed by an expert trichologist observer and presented a concordance higher than 90% with the algorithm identifying structures described previously. Evolution of the cases was followed up to truly determine their response to treatment and, therefore, to assess the predictive value of the algorithm. RESULTS In total, 32 of 40 (80%) images of patients predicted as nonresponders scarcely showed response to the treatment, while 34 of 42 (81%) images of those predicted as responders showed a favorable response to the treatment. CONCLUSIONS The development of an AI algorithm or tool could be useful to predict AA evolution and its response to treatment. However, further research is needed, including larger sample images or trained algorithms, by using images previously classified in accordance with the disease evolution and not with trichoscopic features.

Iproceedings ◽  
10.2196/35433 ◽  
2021 ◽  
Vol 6 (1) ◽  
pp. e35433
Author(s):  
Fernando Alarcón-Soldevilla ◽  
Francisco José Hernández-Gómez ◽  
Juan Antonio García-Carmona ◽  
Celia Campoy Carreño ◽  
Ramon Grimalt ◽  
...  

Background Artificial intelligence (AI) has emerged in dermatology with some studies focusing on skin disorders such as skin cancer, atopic dermatitis, psoriasis, and onychomycosis. Alopecia areata (AA) is a dermatological disease whose prevalence is 0.7%-3% in the United States, and is characterized by oval areas of nonscarring hair loss of the scalp or body without evident clinical variables to predict its response to the treatment. Nonetheless, some studies suggest a predictive value of trichoscopic features in the evaluation of treatment responses. Assuming that black dots, broken hairs, exclamation marks, and tapered hairs are markers of negative predictive value of the treatment response, while yellow dots are markers of no response to treatment according to recent studies, the absence of these trichoscopic features could indicate favorable disease evolution without treatment or even predict its response. Nonetheless, no studies have reportedly evaluated the role of AI in AA on the basis of trichoscopic features. Objective This study aimed to develop an AI algorithm to predict, using trichoscopic images, those patients diagnosed with AA with a better disease evolution. Methods In total, 80 trichoscopic images were included and classified in those with or without features of negative prognosis. Using a data augmentation technique, they were multiplied to 179 images to train an AI algorithm, as previously carried out with dermoscopic images of skin tumors with a favorable response. Subsequently, 82 new images of AA were presented to the algorithm, and the algorithm classified these patients as responders and non-responders; this process was reviewed by an expert trichologist observer and presented a concordance higher than 90% with the algorithm identifying structures described previously. Evolution of the cases was followed up to truly determine their response to treatment and, therefore, to assess the predictive value of the algorithm. Results In total, 32 of 40 (80%) images of patients predicted as nonresponders scarcely showed response to the treatment, while 34 of 42 (81%) images of those predicted as responders showed a favorable response to the treatment. Conclusions The development of an AI algorithm or tool could be useful to predict AA evolution and its response to treatment. However, further research is needed, including larger sample images or trained algorithms, by using images previously classified in accordance with the disease evolution and not with trichoscopic features. Conflicts of Interest None declared.


2021 ◽  
Vol 14 ◽  
pp. 263177452199305
Author(s):  
Hemant Goyal ◽  
Rupinder Mann ◽  
Zainab Gandhi ◽  
Abhilash Perisetti ◽  
Zhongheng Zhang ◽  
...  

The role of artificial intelligence and its applications has been increasing at a rapid pace in the field of gastroenterology. The application of artificial intelligence in gastroenterology ranges from colon cancer screening and characterization of dysplastic and neoplastic polyps to the endoscopic ultrasonographic evaluation of pancreatic diseases. Artificial intelligence has been found to be useful in the evaluation and enhancement of the quality measure for endoscopic retrograde cholangiopancreatography. Similarly, artificial intelligence techniques like artificial neural networks and faster region-based convolution network are showing promising results in early and accurate diagnosis of pancreatic cancer and its differentiation from chronic pancreatitis. Other artificial intelligence techniques like radiomics-based computer-aided diagnosis systems could help to differentiate between various types of cystic pancreatic lesions. Artificial intelligence and computer-aided systems also showing promising results in the diagnosis of cholangiocarcinoma and the prediction of choledocholithiasis. In this review, we discuss the role of artificial intelligence in establishing diagnosis, prognosis, predicting response to treatment, and guiding therapeutics in the pancreaticobiliary system.


Author(s):  
Giang Thu Vu ◽  
Bach Xuan Tran ◽  
Roger S. McIntyre ◽  
Hai Quang Pham ◽  
Hai Thanh Phan ◽  
...  

The rising prevalence and global burden of diabetes fortify the need for more comprehensive and effective management to prevent, monitor, and treat diabetes and its complications. Applying artificial intelligence in complimenting the diagnosis, management, and prediction of the diabetes trajectory has been increasingly common over the years. This study aims to illustrate an inclusive landscape of application of artificial intelligence in diabetes through a bibliographic analysis and offers future direction for research. Bibliometrics analysis was combined with exploratory factor analysis and latent Dirichlet allocation to uncover emergent research domains and topics related to artificial intelligence and diabetes. Data were extracted from the Web of Science Core Collection database. The results showed a rising trend in the number of papers and citations concerning AI applications in diabetes, especially since 2010. The nucleus driving the research and development of AI in diabetes is centered around developed countries, mainly consisting of the United States, which contributed 44.1% of the publications. Our analyses uncovered the top five emerging research domains to be: (i) use of artificial intelligence in diagnosis of diabetes, (ii) risk assessment of diabetes and its complications, (iii) role of artificial intelligence in novel treatments and monitoring in diabetes, (iv) application of telehealth and wearable technology in the daily management of diabetes, and (v) robotic surgical outcomes with diabetes as a comorbid. Despite the benefits of artificial intelligence, challenges with system accuracy, validity, and confidentiality breach will need to be tackled before being widely applied for patients’ benefits.


2021 ◽  
Author(s):  
A.V. Merenkov ◽  
R. Campa ◽  
N.P. Dronishinets

In connection with the active role of Russia and other countries in the design and implementation of devices with artificial intelligence (AI), there is a need to study the opinion of different social groups on this technology and the problems that arise when using it. The purpose of this work is to analyze public opinion on AI, in Russia and various foreign countries, and the possible consequences of its implementation in different areas of human activity. The research has revealed students’ opinions about AI devices and the problems related to their development in Russia. The research methods adopted are a content analysis of foreign publications devoted to the study of public opinion on AI and a questionnaire survey. Overall, 190 students of the Ural Federal University enrolled in Bachelor’s and Master’s programs were interviewed. The analysis of publications devoted to the study of public opinion in the United States, Japan, and Western Europe, as well as the results of our survey, has led to the conclusion that the majority of people have only a vague idea of what AI devices are. Our study has revealed that 23.6% of the respondents know nothing about AI. 36% of the respondents believe that in the near future the most demanded specialists in the labor market will be those who create robots and control their work. The survey has also shown the important role of mass media and general and special education institutions in informing the population about the opportunities and problems that arise when devices that exceed human mental capabilities are created and enter the social fabric. Keywords: public opinion, artificial intelligence, subjects of public opinion, representations of social groups about artificial intelligence


2020 ◽  
Vol 4 (3) ◽  
pp. 42-52
Author(s):  
H. Obeid ◽  
F Hillani, ◽  
R. Fakih ◽  
K. Mozannar

In recent years artificial intelligence has entered a new era, which gives rise to many hopes for powerful states such as the United States and China. In this paper, we analyze the importance and role of artificial intelligence in technological development in each of the two countries on the one hand, and its influence on China-American relations in terms of technological and geopolitical conflict. To get the right results, we rely on a literature review of dozens of articles published on the phenomenon in order to compare the power of artificial intelligence between the United States and China where we found that the US still has technological strength, especially in the field of artificial intelligence, but we can say that a large force is beginning pose a threat for it which is China that has great technological capabilities so, we can say that the United States should work more in this field. Also, we found that artificial intelligence has a primary goal in both countries, it helps China to achieve its ambitions to be the leader of the world, and this intelligence, on the other hand, provides protection and security to the United States. This paper is divided into three sections. The first section focuses on the importance of artificial intelligence in achieving China’s ambitions, the second section explains the role of artificial intelligence in the US protection service, and the third section describes the technological and geopolitical conflict resulting from the competition in artificial intelligence between these two countries. Keywords: Artificial intelligence, United States, China, Conflict, leader.


2021 ◽  
pp. 3-32
Author(s):  
V.N. Leksin

The third and final article of the three-part series of articles «Artificial intelligence in the economy and politics of our time» (the first and second articles of the series were published in the fourth and fifth issues of the journal for this year, respectively) presents the results of a study of the goals, motivations and specifics of the adoption of national strategies to support the development of artificial intelligence in different countries. It is shown that such a strategy in Russia is based on the idea of the most important role of using artificial intelligence in solving the most complex economic, social, and military-political problems of the country. Differences in conceptual approaches to the development of research and practical use of artificial intelligence developments in the national strategies of the largest countries of the world — the United States, China and India.


Author(s):  
Stuart O. Schweitzer ◽  
Z. John Lu

Recognizing that the past often does not predict the future well, this chapter nevertheless offers prescience for the pharmaceutical industry in the next five to ten years. Using the standard economics paradigm of supply, demand, and market equilibrium, it considers the future of the industry in the following aspects: industrial organization, the nascent biosimilar sector, the promise of personalized medicine and digital healthcare information, artificial intelligence, the prospects for outpatient bundled payment programs, the setting of pharmaceutical prices, and the role of the FDA. The most important among them will be the scope and nature of health care reform in the United States and the jurisdiction of the FDA in the coming years.


2021 ◽  
Vol 9 (2) ◽  
pp. 119-129
Author(s):  
Stefka Hristova

In thinking about the ubiquity of algorithmic surveillance and the ways our presence in front of a camera has become engaged with the algorithmic logics of testing and replicating, this project summons Walter Benjamin’s seminal piece <em>The Work of Art in the Age of Its Technological Reproducibility </em>with its three versions, which was published in the United States under the editorial direction of Theodore Adorno. More specifically, it highlights two of the many ways in which the first and second versions of Benjamin’s influential essay on technology and culture resonate with questions of photography and art in the context of facial recognition technologies and algorithmic culture more broadly. First, Benjamin provides a critical lens for understanding the role of uniqueness and replication in a technocratic system. Second, he proposes an analytical framework for thinking about our response to visual surveillance through notions of training and performing a constructed identity—hence, being intentional about the ways we visually present ourselves. These two conceptual frameworks help to articulate our unease with a technology that trains itself using our everyday digital images in order to create unique identities that further aggregate into elaborate typologies and to think through a number of artistic responses that have challenged the ubiquity of algorithmic surveillance. Taking on Benjamin’s conceptual apparatus and his call for understanding the politics of art, I focus on two projects that powerfully critique algorithmic surveillance. Leo Selvaggio’s URME (you are me) Personal Surveillance Identity Prosthetic<em> </em>offers a critical lens through the adoption of algorithmically defined three-dimensional printed faces as performative prosthetics designed to be read and assessed by an algorithm. Kate Crawford and Trevor Paglen’s project Training Humans is the first major exhibition to display a collection of photographs used to train an algorithm as well as the classificatory labels applied to them both by artificial intelligence and by the freelance employees hired to sort through these images.


Subject Hopes of transforming NHS by rapidly deploying AI. Significance The government has announced a 370-million-pound (475-million-dollar) research programme to fund new PhDs in artificial intelligence (AI), with a focus on healthcare. The initiative comes in the wake of other steps to enhance the role of digital technologies and AI in particular in the UK health sector. Impacts The growing profile of private-sector app providers in the NHS will intensify the debate over privatising the service. Opacity in AI algorithms makes it difficult to question or recognise faults with the technology. The United Kingdom is likely to lag behind the United States and China on AI healthcare adoption.


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