scholarly journals SYNTHESIS OF AZO COMPOUNDS DERIVATIVE FROM EUGENOL AND ITS APPLICATION AS A TITRATION INDICATOR

2010 ◽  
Vol 9 (1) ◽  
pp. 95-98 ◽  
Author(s):  
Bambang Purwono ◽  
Catur Mahardiani
Keyword(s):  
Acetic Acid ◽  
Sodium Hydroxide ◽  
1H Nmr ◽  
Sodium Nitrite ◽  
Diazonium Salt ◽  
Azo Compounds ◽  
Chloride Salt ◽  
Acid Condition ◽  
Azo Compound ◽  
Azo Derivatives

The synthesis of azo compounds from eugenol has been carried out by diazotation reaction. The diazonium salt was produced by reaction of aniline and sodium nitrite in acid condition at 0-5 °C temperature to yield benzenediazonium chloride salt. The salt was then reacted with eugenol to produce the azo derivatives. The azo product was analyzed by IR, 1H-NMR, dan GC-MS spectrometer. The results showed that the reaction of benzenediazonium chloride with eugenol gave 4-allyl-2-methoxy-6-hydroxyazobenzene in 34.27% yield for 30 minutes reaction. The derivative of azo compound was dissolved in ethanol and then the color changing was observed in range of pH 9.8-11.1 from yellow to red. Application for titration indicator for acetic acid titrated with sodium hydroxide showed error less than 3.20% compared with phenol phtaline indicator.   Keywords: Eugenol, Azo compound, titration indicator

scholarly journals Synthesis and Characterization of New Azo Compounds Linked to 1, 8-Naphthalimide and Studying Their Ability as Acid-Base Indicators

2019 ◽  
pp. 2341-2352
Author(s):  
Suaad M.H. Al-Majidi ◽  
Mohammed G.A Al-Khuzaie
Keyword(s):  
Diazonium Salt ◽  
Coupling Reaction ◽  
Alkaline Media ◽  
Azo Compounds ◽  
Acid Base ◽  
Naphthalic Anhydride ◽  
Azo Compound ◽  
Basic Solutions ◽  
Specific Reactions

New Azo compounds containing an 1,8-naphthalimide moiety were synthesized from 1, 8-naphthalic anhydride by a reaction with p-phenylenediamine or benzidine to produce 1,8-naphthalimide derivatives (1 or 2), which were converted to diazonium salt derivatives by using sodium nitrite and acetic acid at 0-5 áµ’C. The diazonium salt was subjected to a coupling reaction with different substituted phenol in alkaline media at 0-5 áµ’c to produce azo compound derivatives (3-14). The New Azo compound derivatives (3-14) were identified by 1H-NMR, 13C-NMR, and FTIR and by measuring characteristic physical properties and specific reactions. Also, the ability of the prepared azo compounds to work as acid-base indicator was investigated, since azo dyes have different and sharp colors in acidic or basic solutions.

Production of monosaccharides from poplar by a two-step hydrogen peroxide-acetic acid and sodium hydroxide pretreatment

2021 ◽  
Vol 170 ◽  
pp. 113820
Author(s):  
Hong Liao ◽  
Jiaxin You ◽  
Peiyao Wen ◽  
Wenjun Ying ◽  
Qianqian Yang ◽  
...  
Keyword(s):  
Hydrogen Peroxide ◽  
Acetic Acid ◽  
Sodium Hydroxide

scholarly journals Kinetics and Mechanism of the Change of the 4-Nitrobenzylthio-System into 4,4′-Diformylazoxybenzene in Alkaline Dioxane-Water Media

1985 ◽  
Vol 40 (11) ◽  
pp. 1128-1132
Author(s):  
Y. Riad ◽  
Adel N. Asaad ◽  
G.-A. S. Gohar ◽  
A. A. Abdallah
Keyword(s):  
Acetic Acid ◽  
Sodium Hydroxide ◽  
Rate Constants ◽  
Main Product ◽  
Reaction Medium ◽  
Aqueous Dioxane ◽  
Proton Abstraction ◽  
First Order ◽  
Water Media ◽  
Different Temperatures

Sodium hydroxide reacts with α -(4-nitrobenzylthio)-acetic acid in aqueous-dioxane media to give 4,4'-diformylazoxybenzene as the main product besides 4,4'-dicarboxyazoxybenzene and a nitrone acid. This reaction was kinetically studied in presence of excess of alkali in different dioxane-water media at different temperatures. It started by a fast reversible a-proton abstraction step followed by two consecutive irreversible first-order steps forming two intermediates (α -hydroxy, 4-nitrosobenzylthio)-acetic acid and 4-nitrosobenzaldehyde. The latter underwent a Cannizzaro's reaction, the products of which changed in the reaction medium into 4,4'-diformylazoxybenzene and 4,4'-dicarboxyazoxybenzene. The rate constants and the thermodynamic parameters of the two consecutive steps were calculated and discussed. A mechanism was put forward for the formation of the nitrone acid.Other six 4-nitrobenzyl, aryl sulphides were qualitatively studied and they gave mainly 4,4'-diformylazoxybenzene beside 4,4'-dicarboxyazoxybenzene or its corresponding azo acid.

Reactions of Tertiary Butyl Hypochlorite. I. The Chlorination of Aromatic Nitroamines

1959 ◽  
Vol 12 (3) ◽  
pp. 430 ◽  
Author(s):  
KH Pausacker ◽  
JG Scroggie
Keyword(s):  
Azo Compounds ◽  
Direct Oxidation ◽  
Tertiary Butyl ◽  
Azo Compound

Tertiary butyl hypochlorite reacts with 2-nitroaniline, 4-nitroaniline, N-methyl-4-nitroaniline, and NN-dimethyl-4-nitroaniline to form excellent yields of nuclear-chlorinated derivatives. Direct oxidation, to form azo compounds, is also observed with 4-nitroaniline and the yield of azo compound increases at higher temperatures. Demethylation also occurs when N-methyl-4-nitroaniline and NN-dimethyl-4-nitro-aniline are used.

scholarly journals 6-[1-Acetyl-5-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazole-3-yl]-2(3H)-benzoxazolone

Molbank ◽  
10.3390/m1021 ◽  
2018 ◽  
Vol 2018 (4) ◽  
pp. M1021
Author(s):  
Yordanka Ivanova ◽  
Antonya Todorova ◽  
Christo Chanev ◽  
Ognyan Petrov
Keyword(s):  
Acetic Acid ◽  
Hydrazine Hydrate ◽  
1H Nmr ◽  
Elemental Analysis ◽  
13C Nmr ◽  
Title Compound ◽  
Target Compound

The title compound, 6-[1-acetyl-5-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-3-yl]-2(3H)-benzoxazolone, was synthesized by condensation of 6-[3-(4-methoxyphenyl)-2-propenoyl]-2(3H)-benzoxazolone (1) and hydrazine hydrate in acetic acid in 84% yield. The structure of the target compound was confirmed using 1H-NMR, 13C-NMR, IR, MS, and elemental analysis.

Thermochemical Ablation in an Ex-vivo Porcine Liver Model Using Acetic Acid and Sodium Hydroxide: Proof of Concept

2010 ◽  
Vol 21 (10) ◽  
pp. 1573-1578 ◽  
Author(s):  
Joseph L. Farnam ◽  
Benjamin C. Smith ◽  
Brandon R. Johnson ◽  
Rodolfo Estrada ◽  
Theresa L. Edelman ◽  
...  
Keyword(s):  
Acetic Acid ◽  
Sodium Hydroxide ◽  
Ex Vivo ◽  
Proof Of Concept ◽  
Porcine Liver ◽  
Liver Model

scholarly journals Quinazolin-4(3H)-ones and 5,6-Dihydropyrimidin-4(3H)-ones from β-Aminoamides and Orthoesters

Molecules ◽  
2018 ◽  
Vol 23 (11) ◽  
pp. 2925 ◽  
Author(s):  
Joshua Gavin ◽  
Joel Annor-Gyamfi ◽  
Richard Bunce
Keyword(s):  
Acetic Acid ◽  
Melting Point ◽  
1H Nmr ◽  
13C Nmr ◽  
Pressure Tube ◽  
Absolute Ethanol ◽  
Basic Nitrogen ◽  
One Step ◽  
Ft Ir

Quinazolin-4(3H)-ones have been prepared in one step from 2-aminobenzamides and orthoesters in the presence of acetic acid. Simple 2-aminobenzamides were easily converted to the heterocycles by refluxing in absolute ethanol with 1.5 equivalents of the orthoester and 2 equivalents of acetic acid for 12–24 h. Ring-substituted and hindered 2-aminobenzamides as well as cases incorporating an additional basic nitrogen required pressure tube conditions with 3 equivalents each of the orthoester and acetic acid in ethanol at 110 °C for 12–72 h. The reaction was tolerant towards functionality on the benzamide and a range of structures was accessible. Workup involved removal of the solvent under vacuum and either recrystallization from ethanol or trituration with ether-pentane. Several 5,6-dihydropyrimidin-4(3H)-ones were also prepared from 3-amino-2,2-dimethylpropionamide. All products were characterized by melting point, FT-IR, 1H-NMR, 13C-NMR, and HRMS.

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