scholarly journals General Practitioners’ Autonomy in the Management of Non-Communicable Diseases (NCDs) in the JKN Era: Is It Feasible?

Author(s):  
Nur Afrainin Syah

Demographic, epidemiological, and nutritional transitions increase life expectancy, changes in lifestyles and behaviors of Indonesian people. These changes are resulting in a growing contribution of non-communicable diseases (NCDs) to morbidity and mortality, especially metabolic disorders, such as type 2 diabetes mellitus (DM), hypertension, and dyslipidemia. Approximately 10.9% of the Indonesian population above 15 years old suffers from type 2 DM (21.2 million) and 34.1% have hypertension (66.3 million) in 2018. These figures increase significantly from 2013 figure; 6.9% and 25.8% respectively1. The metabolic disorders, which in turn, are responsible for vascular problems such as renal failure, stroke, and heart attack. Not surprisingly, then, 60% of Indonesian national health insurance (JKN) funds are spent on the NCDs. This condition causes a deficit and threatens the sustainability of the JKN program.

Author(s):  
Setiawati Setiawati ◽  
Septina Rahmayati ◽  
Marliyana Marliyana

Background: Type II Diabetes Mellitus is the most common non-communicable diseases among the elderly. Several modifiable and non-modifiable factors contributed to the occurrence of these diseases.Purpose: Describing of the factors related to the occurrence of type 2 Diabetes Mellitus among the elderly at an integrated development post non- communicable diseases (Posbindu PTM Way Halim) Bandar Lampung-Indonesia.Methods: The type of this research is quantitative, from database in the medical record with total of 74 by purposive random sampling. Data analyzed by univariate and bivariate (chi-squared).Results: Smoker (p-value =  0.016; OR 3.429), physical activity (p-value = 0,000 ; OR 7.467) and waist circumference (p-value = 0.011 OR 4,091). Those were main factors that influence  to the occurrence of DM among eldely. Conclusion: It is suggested to management Public Health Services (Puskesmas) to establish a more integrated development post non- infectious diseases (Posbindu) to reach all the elderly. By controlling all of the factors that influence the occurrence of type II DM in various ways, so that the elderly will have a better life and prevent the complications


Author(s):  
A. I. Kuzin ◽  
M. A. Cherednikova ◽  
A. A. Vasilyev ◽  
O. V. Kamerer

The study was undertaken to examine the specific features of the lipid spectrum in patients with metabolic disorders in the absence or presence of arterial hypertension (AH) and type 2 diabetes mellitus (DM) The study covered 176 patients with metabolic disorders, 138 patients were diagnosed as having AH, of them 39 patients had type 2 DM Clinical and laboratory studies involved the estimation of the body mass index, waist/hip ratio, and lipid spectrum All the patients were divided into 3 groups I) 38 without AH and type 2 DM, 2) 99 with isolated AH without type 2 DM, 3) 39 with AH and type 2 DM The higher severity of abdominal obesity was associated with enhanced dyslipidemia atherogemcity The development of AH m the presence of metabolic disorders was accompanied by higher total cholesterol levels, which may be considered as aggravated endothelial dysfunction Its concurrence with type 2 DM was attended by transformation of metabolic to diabetic dyslipidemia The study has yielded a new index that characterizes dyslipidemia atherogemcity in patients with metabolic disorders


2018 ◽  
Vol 3 (2) ◽  
pp. 18-23
Author(s):  
Jyoti Ratan Ghosh ◽  
Piya Ghosh Dastidar ◽  
Biswarup Dey ◽  
Piyali Das ◽  
Arup Ratan Bandyopadhyay

BackgroundDermatoglyphics is frequently used in understanding the proximity with non-communicable diseases including diabetes mellitus. Diabetes mellitus is one of the most common non-communicable diseases all over the world. The present study is an attempt to understand the association of palmer dermatoglyphic traits [i.e. a-b ridge count (ABRC), c-d ridge count (CDRC), presence of multiple number of axial triradii (t, t' & t") in a single palm, td ridge count (TDRC), atd angle, btd angle and ctd angle] with type 2 diabetes mellitus (T2DM). Material and methodsSubjects included 30 clinically diagnosed adult female T2DM patients and 60 healthy controls from the Bengalee Hindu Caste population of West Bengal, India. Bilateral palm prints were collected following standard ink and roller method. Results Present study revealed that T2DM patients have significantly (p<0.05) lower ABRC, CDRC and TDRC. On the other hand, significantly (p<0.05) higher presence of multiple number of axial triradii t, t' & t" was found in the palm of T2DM patients compared to the controls. T2DM patients also demonstrated significantly (p<0.05) higher values of atd and btd angle. However, T2DM patients demonstrated significantly (p<0.05) lower value of ctd angle than that of controls, only when both hand were considered. ConclusionThe results the present study indicated that dermatoglyphic traits may be used for early identification of at risk individuals for surveillance with a view to prevent the disease onset.Journal of Biomedical Sciences, Vol. 3, No. 2, 2016


2021 ◽  
Vol 22 (7) ◽  
pp. 3566
Author(s):  
Chae Bin Lee ◽  
Soon Uk Chae ◽  
Seong Jun Jo ◽  
Ui Min Jerng ◽  
Soo Kyung Bae

Metformin is the first-line pharmacotherapy for treating type 2 diabetes mellitus (T2DM); however, its mechanism of modulating glucose metabolism is elusive. Recent advances have identified the gut as a potential target of metformin. As patients with metabolic disorders exhibit dysbiosis, the gut microbiome has garnered interest as a potential target for metabolic disease. Henceforth, studies have focused on unraveling the relationship of metabolic disorders with the human gut microbiome. According to various metagenome studies, gut dysbiosis is evident in T2DM patients. Besides this, alterations in the gut microbiome were also observed in the metformin-treated T2DM patients compared to the non-treated T2DM patients. Thus, several studies on rodents have suggested potential mechanisms interacting with the gut microbiome, including regulation of glucose metabolism, an increase in short-chain fatty acids, strengthening intestinal permeability against lipopolysaccharides, modulating the immune response, and interaction with bile acids. Furthermore, human studies have demonstrated evidence substantiating the hypotheses based on rodent studies. This review discusses the current knowledge of how metformin modulates T2DM with respect to the gut microbiome and discusses the prospect of harnessing this mechanism in treating T2DM.


2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
N M Mahrouseh ◽  
D W Njuguna ◽  
O A Varga

Abstract Background There is an alerting increase in the population affected by type 2 diabetes mellitus (T2DM) in the European Union (EU) with significant socioeconomic burden. According to an estimation by the International Diabetes Federation, by 2030, the total number of diabetic patients will be 38 million in EU. The “screen and treat” strategies that predominantly applied in policies to prevent T2DM have not achieved significant success, as reported by a large systematic review and meta-analysis published in 2017. Although the member states of the EU have almost full responsibilities for actions in the field of health, the EU has to tackle non-communicable diseases by targeting health determinants and lifestyle mostly through non-binding policies. The goal of this work is to review the T2DM prevention policies in the EU and compare with tobacco policies, from a legal perspective. Methods Following the systematic search and screening of policies from EUR-lex, a content analysis was carried out by using MonQcle as publicly available legal text document analysis platform, by two coders. The search was limited for regulations, directives and white papers. Results Our data collection consisted of 19 documents including 10 regulations, 6 directives and 3 white papers with relevance to T2DM, covering the following topics: health infrastructure and services, informational policies, economic policies, environmental policies, command and control and social policies. The identified policies covered the time frame of 1972 to 2020. Diabetes was targeted as part of non-communicable diseases. None of the policies was legally binding addressing T2DM directly which is in sharp contrast to the tobacco control policies in the EU. Conclusions T2DM, in fact, is largely preventable. EU institutions should consider to reframe T2DM prevention strategies and consider applying a wide range of population-level legislative and innovative actions to prevent T2DM e.g. taxes on unhealthy food products. Key messages T2DM is a largely preventable disease, effective legal tools should be created and applied matching the scale of such public health problem. T2DM policies of the EU may be subject to change due to additional value of actions taken by the EU compared to that could have been achieved by member states alone.


2021 ◽  
Author(s):  
Samira Arbabi Jam ◽  
Shahab Rezaeian ◽  
Farid Najafi ◽  
Behroz Hamze ◽  
Ebrahim Shakiba ◽  
...  

Abstract Background: Dietary factors and inflammation are associated with most non-communicable diseases (NCDs). The Dietary Inflammatory Index (DII) is a developed validated assessment tool. This study was conducted to assessed association of DII with the hypertension and type 2 diabetes mellitus (T2DM). Methods: This cross-sectional analysis was performed on 9,811 participants of 35 to 65 years of the base-line phase data of Ravansar Non-Communicable Diseases (RaNCD) cohort study. The DII was calculated using 31 parameters food of food frequency questionnaire (FFQ). The estimates were performed using univariable and multivariable logistic regression.Results: The mean DII scores in healthy participants was -2.32± 1.60, in participant with T2DM, hypertension and both were -2.23± 1.59, -2.45± 1.60 and -2.25± 1.60, respectively (P= 0.011). Pre-inflammatory diet was significantly higher in male compared to female (P<0.001). In the most pro-inflammatory diet was significantly higher BMI (body mass index), triglyceride, energy intake, smokers; and was significantly lower socio-economic status (SES), physical activity and HDL-C compared to the most anti-inflammatory diet. Participants with T2DM, hypertension and comorbidity had a significantly higher mean of anthropometry indices (P<0.001) and lipid profile compared to healthy subjects (P<0.001). After adjustment for age, sex and physical activity, the odds of T2DM in the fourth quartile of DII was 1.48 (95% CI: 1.19, 1.85) times higher compared to the first quartile of DII. Conclusions: Pro-inflammatory diet was weak associations with hypertension. Pro-inflammatory diet was significant associations with increasing T2DM and its related risk factors. Modification of diet and lifestyle is suggested to reduce inflammation.


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