Quantum dots and their potential biomedical applications in photosensitization for photodynamic therapy

Nanomedicine ◽  
2009 ◽  
Vol 4 (3) ◽  
pp. 353-363 ◽  
Author(s):  
Elnaz Yaghini ◽  
Alexander M Seifalian ◽  
Alexander J MacRobert
Keyword(s):  
Quantum Dots ◽  
Photodynamic Therapy ◽  
Biomedical Applications

scholarly journals Organic dots (O-dots) for theranostic applications: preparation and surface engineering

RSC Advances ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 2253-2291
Author(s):  
Amin Shiralizadeh Dezfuli ◽  
Elmira Kohan ◽  
Sepand Tehrani Fateh ◽  
Neda Alimirzaei ◽  
Hamidreza Arzaghi ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Photodynamic Therapy ◽  
Photothermal Therapy ◽  
Biomedical Applications ◽  
Surface Engineering ◽  
Graphene Quantum Dots ◽  
Carbon Quantum Dots ◽  
Cargo Delivery ◽  
Bio Imaging ◽  
Theranostic Applications

Organic dots is a term used to represent materials including graphene quantum dots and carbon quantum dots because they rely on the presence of other atoms (O, H, and N) for their photoluminescence or fluorescence properties. Cargo delivery, bio-imaging, photodynamic therapy and photothermal therapy are major biomedical applications of organic dots.

scholarly journals Core-shell Semiconductor Nanocrystals: Effect of Composition, Size, Surface Coatings on their Optical Properties, Toxicity and Pharmacokinetics

2017 ◽  
Vol 23 (3) ◽  
pp. 340-349 ◽  
Author(s):  
Wafa' T. Al-Jamal
Keyword(s):  
Quantum Dots ◽  
Optical Properties ◽  
Photodynamic Therapy ◽  
Biomedical Applications ◽  
Semiconductor Nanocrystals ◽  
Organic Dye ◽  
Surface Coatings ◽  
Core Shell ◽  
Biomedical Field

Quantum dots are semiconducting nanocrystals that exhibit extraordinary optical properties. QD have shown higher photostability compared to standard organic dye type probes. Therefore, they have been heavily explored in the biomedical field. This review will discuss the different approaches to synthesis, solubilise and functionalise QD. Their main biomedical applications in imaging and photodynamic therapy will be highlighted. Finally, QD biodistribution profile and in vivo toxicity will be discussed.

scholarly journals Multifunctional graphene quantum dots for combined photothermal and photodynamic therapy coupled with cancer cell tracking applications

RSC Advances ◽  
2017 ◽  
Vol 7 (9) ◽  
pp. 5251-5261 ◽  
Author(s):  
Mukeshchand Thakur ◽  
Mukesh Kumar Kumawat ◽  
Rohit Srivastava
Keyword(s):  
Quantum Dots ◽  
Photodynamic Therapy ◽  
Carbon Source ◽  
Cancer Cell ◽  
Biomedical Applications ◽  
Cell Tracking ◽  
Graphene Quantum Dots ◽  
Green Factory ◽  
Fig Tree

An Indian fig tree serves as a green factory by providing withered leaves as a carbon source for graphene quantum dots synthesis. The quantum dots are multi-functional and have tremendous theranostic biomedical applications.

scholarly journals Influence of Graphene Quantum Dots Surface Charge on their Uptake and Clearance in Melanoma Cells

2021 ◽  
Author(s):  
Lakshmi Narashimhan Ramana ◽  
Le N.M. Dinh ◽  
Vipul Agarwal
Keyword(s):  
Quantum Dots ◽  
Surface Charge ◽  
Biomedical Applications ◽  
Graphene Quantum Dots ◽  
Melanoma Cells ◽  
Rapid Clearance

Graphene quantum dots (GQDs) continue to draw interest in biomedical applications. However, their efficacy gets compromised due to their rapid clearance from body. On one side, rapid clearance is desired...

scholarly journals Synthesis and Characterization of Polyvinylpyrrolidone-Modified ZnO Quantum Dots and Their In Vitro Photodynamic Tumor Suppressive Action

2021 ◽  
Vol 22 (15) ◽  
pp. 8106
Author(s):  
Tianming Song ◽  
Yawei Qu ◽  
Zhe Ren ◽  
Shuang Yu ◽  
Mingjian Sun ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Photodynamic Therapy ◽  
Inhibitory Effect ◽  
Therapeutic Effects ◽  
In Vivo Experiments ◽  
Potential Applications ◽  
Zno Quantum Dots ◽  
Zno Qds

Despite the numerous available treatments for cancer, many patients succumb to side effects and reoccurrence. Zinc oxide (ZnO) quantum dots (QDs) are inexpensive inorganic nanomaterials with potential applications in photodynamic therapy. To verify the photoluminescence of ZnO QDs and determine their inhibitory effect on tumors, we synthesized and characterized ZnO QDs modified with polyvinylpyrrolidone. The photoluminescent properties and reactive oxygen species levels of these ZnO/PVP QDs were also measured. Finally, in vitro and in vivo experiments were performed to test their photodynamic therapeutic effects in SW480 cancer cells and female nude mice. Our results indicate that the ZnO QDs had good photoluminescence and exerted an obvious inhibitory effect on SW480 tumor cells. These findings illustrate the potential applications of ZnO QDs in the fields of photoluminescence and photodynamic therapy.

Exploration of Graphitic-C3N4 Quantum Dots for Microwave-Induced Photodynamic Therapy

2017 ◽  
Vol 3 (8) ◽  
pp. 1836-1844 ◽  
Author(s):  
Xiao Chu ◽  
Kang Li ◽  
Hongyu Guo ◽  
Huibin Zheng ◽  
Suzanne Shuda ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Photodynamic Therapy

MPA-capped CdTe quantum dots exposure causes neurotoxic effects in nematode Caenorhabditis elegans by affecting the transporters and receptors of glutamate, serotonin and dopamine at the genetic level, or by increasing ROS, or both

Nanoscale ◽  
2015 ◽  
Vol 7 (48) ◽  
pp. 20460-20473 ◽  
Author(s):  
Tianshu Wu ◽  
Keyu He ◽  
Qinglin Zhan ◽  
Shengjun Ang ◽  
Jiali Ying ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Caenorhabditis Elegans ◽  
Biomedical Applications ◽  
Biological Properties ◽  
Cdte Quantum Dots ◽  
Nematode Caenorhabditis Elegans ◽  
Neurotoxic Effects ◽  
Genetic Level

As quantum dots (QDs) are widely used in biomedical applications, the number of studies focusing on their biological properties is increasing.

Highly Luminescent, Stable, and Red-Emitting CsMgxPb1–xI3 Quantum Dots for Dual-Modal Imaging-Guided Photodynamic Therapy and Photocatalytic Activity

2021 ◽  
Author(s):  
Girum Getachew ◽  
Chiranjeevi Korupalli ◽  
Akash S. Rasal ◽  
Worku Batu Dirersa ◽  
Mochamad Z. Fahmi ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Photocatalytic Activity ◽  
Photodynamic Therapy
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