scholarly journals Niosomes: A Novel Carrier Drug Delivery System

2021 ◽  
Vol 11 (1) ◽  
pp. 162-170
Author(s):  
Arumugam Kauslya ◽  
Payal D Borawake ◽  
Jitendra V Shinde ◽  
Rajashree S Chavan
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Cost Effective ◽  
Pharmacological Action ◽  
Oral Route ◽  
Target Cells ◽  
Factors Affecting ◽  
Ophthalmic Delivery ◽  
Novel Drug

Niosomes are a novel drug delivery system, in which the medication is encapsulated in a vesicle. The vesicle is composed of a bilayer of non-ionic surfactants. Niosomes are mostly preferred than liposomes because they are stable and cost effective. Niosomes potentiate the pharmacological action of the drug molecules by delaying the clearance of the drug from the circulation, protecting the drug from biological environment and restricting the effects only to the target cells. In novel drug delivery it has applications on treatment of cancer, used as a carrier in haemoglobin, delivery of the peptide drugs through oral route, in treatment of leishmaniasis, in ophthalmic delivery and as carrier in dermal drug delivery. This review article focuses on the composition, advantages, types of niosomes, methods of preparation, characterization and application of the vesicular system. Keywords: Niosomes, Composition, Types, Method of preparation, Factors affecting, Application.

scholarly journals An Overview of Therapeutic Applications

2017 ◽  
pp. 366-390
Author(s):  
Sandeep Waghulde ◽  
Pravin Naik
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Pharmacological Action ◽  
The Body ◽  
Traditional System ◽  
System A ◽  
Target Organs ◽  
Novel Drug Delivery System ◽  
Novel Drug

Over the last few years' great advances have been made on the development drug delivery systems for different purposes for targeting the diseased conditions. Novel drug delivery originates from polymers or associated with some devices is generally related with the emergence of novel characteristics. These changes are what eventually comprise the value of drug delivery system and Novel drug delivery system. Novel properties become existed without making new materials. Novel drug delivery system comparable to traditional system, following Targeted Drug Delivery System (TDDS) is also called targeting drug system. A new drug delivery system makes the drugs densely gather pathological-change structures, and has an improved healing effect and less toxic side effects. The drugs can improve the strength of pharmacological action and reduce the bad effect all over the body, for they release in the target organs.

scholarly journals Floating type drug delivery system: a review

2019 ◽  
Vol 9 (2) ◽  
pp. 428-432 ◽  
Author(s):  
S K Datir ◽  
P.B. Patil ◽  
R.B. Saudagar
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Factors Affecting ◽  
Long Span ◽  
Floating Drug Delivery ◽  
Proximal Small Intestine ◽  
Floating Drug Delivery System ◽  
Floating Type ◽  
Novel Drug

Floating Type drug delivery system retains the dosage form for a long span. They provide local delivery to specific region like stomach and proximal small intestine and shows better bioavailability and improve therapeutic activity and substantial benefit to patients. FDDS is one of the novel drug delivery system to prolong gastric retention time. Various forms of gastro retentive drug delivery system, such as floating and non- floating. Keywords: Floating Drug Delivery System, Classification effervescent, non-effervescent, and Factors affecting FDDS.

scholarly journals An Overview of Nanogel –Novel Drug Delivery System

2019 ◽  
Vol 7 (2) ◽  
pp. 47-55 ◽  
Author(s):  
Saloni Jain ◽  
Rahul Kumar Ancheria ◽  
Saumya Shrivastava ◽  
Shankar Lal Soni ◽  
Mukesh Sharma
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Drug Loading ◽  
Target Cells ◽  
Innovative Drug ◽  
Device Implantation ◽  
Nonspecific Effects ◽  
High Degree ◽  
Novel Drug

Nanogels are innovative drug delivery system that can play an integral part in pointing out many issues related to old and modern courses of treatment such as nonspecific effects and poor stability. Biomedical and pharmaceutical applications of Nanogels have been explored for tissue regeneration, wound healing, surgical device, implantation, and peroral, rectal, vaginal, ocular, and transdermal drug delivery. Nanogels are proficiently internalized by the target cells, avoid accumulating in nontarget tissues thereby lower the therapeutic dosage and minimize harmful side effects. Nanogels may be defined as highly cross linked nano-sized hydrogels ranges from 20-200 nm. They can be administered through various routes, including oral, pulmonary, nasal, parenteral, intra-ocular etc. They have a high degree of drug loading capacity and it shows better permeation capabilities due to smaller size. Nanogels are the novel drug delivery systems for both hydrophilic and hydrophobic drugs.  

scholarly journals Niosomes: A Promising Novel Nano Carrier for Drug Delivery

2021 ◽  
pp. 53-66
Author(s):  
Nirmal Shah ◽  
Rahul Prajapati ◽  
Dipti Gohil ◽  
Piyush Sadhu ◽  
Snehal Patel
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Oral Drug Delivery ◽  
Cost Effective ◽  
Controlled Drug Release ◽  
Oral Drug ◽  
Ionic Surfactant ◽  
Oral Drug Delivery System ◽  
Novel Drug

Niosomes are vesicles, which are formulated by hydrating the mixture of cholesterol, non-ionic surfactant and other biodegradable lipids. Niosomes increase the drug activity as compare to their conventional dosage form of a drug. Niosomes can be used as carrier of amphiphilic and lipophilic drugs. Niosomes may overcome the issues related to instability, fast degradation, low bioavailability, and insolubility of medications. The structure of niosomes either multilamellar or unilamellar, is depends on the method of formulation. Niosomes contain very efficient drug delivery potential for site-specific delivery of anti-cancer, anti-infective agents, etc. Niosomes are stable as well as cost effective carriers as compared with other drug formulations. Niosomes also have various applications in parental drug delivery system, topical drug delivery system, oral drug delivery system and novel drug delivery system such as targeted drug delivery system and controlled drug release system.

An Overview of Therapeutic Applications

2017 ◽  
pp. 1-25
Author(s):  
Sandeep Waghulde ◽  
Pravin Naik
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Pharmacological Action ◽  
The Body ◽  
Traditional System ◽  
System A ◽  
Target Organs ◽  
Novel Drug Delivery System ◽  
Novel Drug

Over the last few years' great advances have been made on the development drug delivery systems for different purposes for targeting the diseased conditions. Novel drug delivery originates from polymers or associated with some devices is generally related with the emergence of novel characteristics. These changes are what eventually comprise the value of drug delivery system and Novel drug delivery system. Novel properties become existed without making new materials. Novel drug delivery system comparable to traditional system, following Targeted Drug Delivery System (TDDS) is also called targeting drug system. A new drug delivery system makes the drugs densely gather pathological-change structures, and has an improved healing effect and less toxic side effects. The drugs can improve the strength of pharmacological action and reduce the bad effect all over the body, for they release in the target organs.

scholarly journals Novel study in fast dissolving drug delivery system: a review

2015 ◽  
Vol 3 (01) ◽  
pp. 93-107
Author(s):  
Sparsh Gupta ◽  
Rakesh Roshan Mali ◽  
Vashali Goel
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Oral Route ◽  
Conventional Tablet ◽  
System A ◽  
Tablet Disintegration ◽  
Novel Drug ◽  
Physical And Chemical ◽  
Fast Disintegrating Tablets

Novel drug delivery systems are becoming increasingly sophisticated as pharmaceutical scientists acquire a better understanding of the physicochemical and bio-chemical parameters pertinent to their performance. Despite tremendous advancements in drug delivery, the oral route remains the perfect route for the administration. Novel drug delivery system assists to achieve better patient compliance. Fast dissolving tablets are one of them.FDT have benefits such as accurate dosing, easy portability and manufacturing, good physical and chemical stability and an ideal alternative for pediatric and geriatric patients. FDDT formulation combines the advantage of both liquid and conventional tablet formulation while also offering advantage over both traditional dosage forms. Some tablets are designed to dissolve in saliva remarkably fast, within a few seconds, and are true fast- dissolving tablets. Others contain agents to enhance the rate of tablet disintegration in the oral cavity, and are more appropriately termed fast-disintegrating tablets, as they may take up to a minute to completely disintegrate.

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