scholarly journals Assessment of Disease Knowledge, Medication Adherence, HRQOL in COPD Patients at a South Indian Tertiary Care Hospital

2021 ◽  
Vol 11 (5) ◽  
pp. 57-60
Author(s):  
S. Padmakar ◽  
R.B. Purandhar Chakravarthy ◽  
Prodduturu Sai Karthik ◽  
B.U. Charitha ◽  
T. Harini ◽  
...  

Introduction: Chronic obstructive pulmonary disease (COPD) is a progressive, life-threatening disease of the lungs, gradually causes breathlessness and predisposes to exacerbations and serious illness. The main objectives of the study are to evaluate disease knowledge, medication adherence, and health-related quality of life among COPD patients. Methodology: A Hospital-based, single-entered prospective observational study was conducted at a government general hospital, Andhra Pradesh. India after ethical committee approval. This study was conducted for 6 months with a sample size of 80 patients. Results: According to our study, the majority of the patients 36 (45%) don’t have disease knowledge, where a few numbers of patients 7 (8.75%) is having disease knowledge as per BCKQ score values. 11.25% of patients have the lowest MMAS scores whereas 58.75% were found to have higher MMAS scores and 37.5% of total patients have higher CAT scores, and 12.5% of patients have lower CAT scores. Conclusion: We found that majority of the patients have poor disease knowledge, lower adherence to medication regimens, and substandard HRQOL. Keywords: COPD knowledge, medication adherence, and HRQOL.

Author(s):  
Sristi Neupane ◽  
Parbati Thapa ◽  
Anil Giri ◽  
Sumitra Shrestha ◽  
Nirmal Raj Marasine

Objective: Patients with chronic obstructive pulmonary disease (COPD) are known to have poor medication adherence in Nepal. Various factors affect the medication adherence of COPD patients. Therefore, we aimed to evaluate the medication adherence and its associated factors among the COPD patients in tertiary care hospitals in central Nepal. Methods: A hospital-based cross-sectional study was carried out among 164 patients aged ≥18 years, diagnosed with and under medication(s) of COPD for at least 6 months from  September 2017 to March 2018, in a tertiary care hospital in central Nepal, using a purposive sampling technique. Morisky Green Levine Adherence (MGLA) score was employed to determine the rate of medication adherence. The differences between the two groups (adherent and non-adherent) were tested using independent t-test, and Chi-square tests, p<0.05 was considered statistically significant.   Results: Patients were mostly ≥60 years (87.1%) and female (56.7%). The majority of the patients were found adherent to the prescribed treatment (108; 65.9%). The major reason for non-adherence was seem to be stopping medicine when feeling better (41.08%) and most of the patients had discontinued the medication due to experience of symptomatic relief (42.9%).Medication adherence was statistically significant with age group at p=0.040, educational status p=0.020, no. of daily drugs p= 0.029, and health behavior of the patients (p= 0.025). Conclusion: Our study suggested that two-third of COPD patients were adherent to their medication, and age, education, number of drugs, and health behaviors of the patients were the most influencing factors for medication adherence.


2014 ◽  
Vol 4 (3) ◽  
pp. 151-155
Author(s):  
Naser Ahmed ◽  
Rukhsana Parvin ◽  
Md Abul Kalam Azad

Background: Chronic obstructive pulmonary disease (COPD) is usually associated with polycythemia. It is assumed that systemic inflammatory components of COPD can interfere with erythropoietin and can result in anemia of chronic disease which will impair the functional capacity of these patients and also increase morbidity and mortality. Objective: To evaluate anemia status in COPD patients. Materials and Methods: This cross-sectional study was conducted in clinically stable 50 COPD patients in the outpatient department of Medicine in Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka during the period of July to December 2011. The demographic characteristics, smoking habit, duration of disease, types and severity of anemia, BMI and results of 6-minute walk test were recorded. Results: Out of 50 COPD patients, 76% were male and 24% were female. Among them 32% patients were anemic, 20% were polycythemic and 48% patients had normal hemoglobin. Among the anemic patients with COPD, 87% were male and 13% were female,75% were mildly anemic and 4% moderately anemic, 62.5% had normocytic and 37.5% had microcytic anemia. Conclusion: Anemia in COPD patients is often overlooked and underestimated. Clinicians should be aware of the presence of anemia in patients with COPD so that appropriate treatment could be initiated to improve the quality of life and prognosis DOI: http://dx.doi.org/10.3329/jemc.v4i3.20943 J Enam Med Col 2014; 4(3): 151-155


Author(s):  
Pooja M. Akhtar ◽  
Sujata Yardi ◽  
B. O. Tayade ◽  
Mayuri Pathak ◽  
Bhargavi Saraf

Background: Co-morbid psychological impairments (depression and anxiety) are common in COPD and are often associated with increased disability, health care usage and morbidity. They also impair quality of life in COPD and are often not fully explored in the clinical management of COPD patients. Psychological distress may, however, contribute to sleep difficulties in all stages of disease severity. Both anxiety and depression have been shown to have a negative effect on the sleep and quality of life (QoL).Objectives: To study the correlation between depression, anxiety and sleep with quality of life in patients with COPD.Methodology: In a tertiary care hospital, this Observational study was conducted on 39 patients of age group 40-70 years, with spirometry confirmed COPD GOLD category I-IV and smokers with more than 5 years of disease who fulfilled were included  in the study. Quality of life was assessed using SGRQ-C, SF-12 and CAT. Depression, Anxiety and Sleep were assessed using PHQ-9, GAD-7 and PSQI questionnaires respectively. The correlation between quality of life scores and mental health scores were analysed using Pearson’s correlation coefficient.Results: Anxiety was significantly correlated with all the sub domains of SGRQ-C, PCS, MCS of SF-12 and the CAT score. (p value<0.001) Similarly, sleep was significantly correlated with all the three QoL Scales. (p value< 0.001) However, depression significantly correlated with all the subdomains of SGRQ-C and CAT except activity sub-domain of SGRQ-C and MCS of SF-12. (p value<0.001)Conclusion: Anxiety, Depression and Sleep moderately correlated with QoL scores in patients with COPD.


Author(s):  
Dharmaraj B. ◽  
Abhijith L. M. ◽  
Jagadeesh K. ◽  
Basavaraj S.

Background: As per GOLD (Global initiative for chronic obstructive lung disease) guidelines bronchodilators are required for symptomatic treatment of chronic obstructive pulmonary disease (COPD) patients. Currently there is no evidence to say about the safety of fixed dose combinations used in COPD patients. Since the drugs are to be taken for longer period, it is essential to know the safety aspects of these drugs. Moreover we don’t have adequate studies and documentation to say that a particular drug combination is better and safer for COPD patients.Methods: Prospective, open labelled, randomized, comparative, interventional clinical study conducted by the Departments of Pharmacology and Pulmonary Medicine of Basaveshwara Medical College and Hospital, Chitradurga in 40 COPD patients.Results: The fixed dose combinations of drugs used in both the treatment groups i.e. salmeterol/fluticasone and tiotropium/formoterol were equally safer and well tolerated. Some side effects noticed during the course of treatment were statistically significant when compared between the 2 groups, however they were milder and predictable adverse drug reactions.Conclusions: Systemic and severe adverse drug reactions were not observed during 8 week treatment period and the local side effects observed were mild in both the treatment groups. Hence the fixed dose combinations of salmeterol or fluticasone and tiotropium or formoterol are found to be safer for maintenance therapy in COPD patients.


2019 ◽  
Vol 10 (01) ◽  
pp. 65-70 ◽  
Author(s):  
Shabir Ahmad Dar ◽  
Bilal Ahmad Bhat ◽  
Naveed Nazir Shah ◽  
Syed Bushra Imtiyaz

ABSTRACT Introduction: Psychiatric morbidity has an increased prevalence in chronic obstructive pulmonary disease (COPD). Patients overall psychosocial status plays an important role in the development of depression which, when major, is said to occur in 19%–42% of cases of COPD. We aimed to study patterns of psychosocial issues in patients with COPD. Materials and Methods: This study was conducted over a period of 6 months in an Outpatient Department of Government Chest Disease Hospital Srinagar. A total of 100 COPD patients and 100 sex- and age-matched controls were included in this study and compared. The diagnosis of COPD was assessed by spirometry. Patterns of psychiatric morbidities were assessed using the Mini-International Neuropsychiatric Interview. Results: The frequency of psychiatric comorbidities was significantly higher (P < 0.001) in COPD patients (47%) as compared to controls (12%). The highest frequency of psychiatric morbidities in COPD patients was major depressive episode in 28% in comparison to 9% of controls. Other morbidities include panic disorder, dysthymia, generalized anxiety disorder, and suicidality. Conclusion: The frequency of psychiatric morbidities is increased in COPD patients as compared to controls. We recommend that all patients with COPD should be screened for psychiatric morbidity as there is enough scope for psychiatric services to be made available to these patients.


Author(s):  
OJS Admin

Chronic obstructive pulmonary disorder (COPD) is an aggravating and major health concern throughout the world. It is estimated that in upcoming years chronic obstructive pulmonary disease will be rankedas third common reason of mortality and fifth common cause of disablement worldwide.


Author(s):  
Uma Rani Adhikari ◽  
Soma Roy

Chronic obstructive pulmonary disease (COPD) is recently the most common chronic lung disease and presents a serious medical, economic, and social problem for people. A correlational survey research was adopted to identify relationship between quality of life and disease severity among Chronic Obstructive Pulmonary Disease (COPD) clients attending Pulmonary Medicine OPD in a selected hospital, Kolkata with the objectives to assess the quality of life of Chronic Obstructive Pulmonary Disease (COPD) clients and to find out correlation between disease severity and quality of life among Chronic Obstructive Pulmonary Disease (COPD) clients. Purposive sampling technique was adapted to select 138 Chronic Obstructive Pulmonary Disease (COPD) clients attending Pulmonary Medicine OPD in a tertiary care hospital, Kolkata. The structured interview schedule was used to collect on demographic data and standardized WHO QOL BREF tool was used to assess Quality of Life. Standardized GOLD criteria were used to assess disease severity of COPD clients. Reliability of the demographic data collection tool was established by inter- rater method and r was 0.77. All the tools were tried out before final data collection. The finding of the study revealed statistically non-significant relationship between all the domain of QOL and disease severity of COPD patients. Total Quality of Life score is also not significantly related with COPD Disease severity score. The study results also showed that QOL is not associated with sociodemographic characteristics. The study concluded that, there is no correlation between quality of life and disease severity.


Author(s):  
Soibam Pahel Meitei ◽  
Sudheer Tale ◽  
Arjun Kumar Negi ◽  
Ruchi Dua ◽  
Rohit Walia ◽  
...  

Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) carries a high risk of venous thromboembolism (VTE). Pulmonary embolism (PE) and AECOPD increase the mortality and morbidity risk associated with each other. Racial and ethnic differences in VTE risk have been documented in multiple studies. However, there is a dearth of reliable Indian data on the same. This study was planned to find the prevalence of VTE in the setting of severe AECOPD in a tertiary care hospital in India and to identify the clinical, laboratory and radiological characteristics of VTE in severe AECOPD. A total of 156 consecutive patients admitted with severe AECOPD and meeting the specified inclusion and exclusion criteria were recruited. Thorough workup of all patients was done including ABG, serum D dimer, ECG, compression ultrasound of lower limbs and 2-D echocardiography. Patients with high pre-test probability score, or intermediate pre-test probability score at presentation with serum D dimer above the age adjusted cut-off underwent computerised tomography pulmonary angiography (CTPA).  Results were analysed using SPSS version 23.  Sixteen (10.3%) patients had VTE, 15 (93.75%) of them being cases of isolated PE. Female gender, higher cumulative past exposure to corticosteroid, higher alveolar-arterial gradient, right ventricular dysfunction, and higher mean pulmonary artery pressure were associated with increased risk for VTE. The prevalence of VTE in AECOPD in this study among an Indian population is higher than among other Asians, but lower than among the Blacks, the Caucasians and the Middle-East ethnicities. Since a vast majority of VTE presents as PE without DVT in the setting of AECOPD, the absence of deep vein thrombosis of lower limbs does not rule PE in the setting.


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