scholarly journals SYNTHESIS AND CHARACTERIZATION OF ACETYLATION OF SUPRA MOLECULAR DENDRIMERS

2021 ◽  
Vol 10 (4) ◽  
pp. 3430-3434
Author(s):  
Hemant Khambete
Keyword(s):  
Molecular Weight ◽  
Size Distribution ◽  
Blood Cells ◽  
Mass Spectra ◽  
Synthesis And Characterization ◽  
Time Duration ◽  
Standard Data ◽  
Ft Ir ◽  
Hemolytic Toxicity

Supra molecular dendrimers have emerged as one of the most interesting themes for researchers work as a result of unique functional architecture and macromolecular characteristics. The main drawback of Supra Molecular dendrimers is, due to presence of –NH2 group at the surface, it causes hemolytic toxicity and hence toxic for the blood cells. In this article, we have systematically modified the surface groups of amine-terminated Supra Molecular dendrimers with acetyl groups. The reported methods of Acetylation are very time consuming and multistep which require large amounts of chemicals. In present work we have synthesized Acetylation Supra Molecular dendrimers using 1-ethyl 3- [3-(dimethylamino) propyl] carbodiimide (EDC) as a cross linking agent. The Acetylated dendrimers were evaluated by color reaction, UV, FT-IR, DSC, Size distribution, NMR and ESI Mass Spectra studies and compared with standard data. The absolute molecular weight and molecular weight distribution of 4.0 G and Acetylated Supra Molecular dendrimers were determined respectively by Size distribution and ESI Mass Spectra respectivel. The results revealed that our approach for Acetylation gives considerable amount of Acetylation, cheap, elimination for ganic solvent, requires less time duration and hence gives a better option for Acetylation of dendrimers.

Synthesis and Characterization of 5-Fluorouracil and Polyethylene Glycol Esters as Prodrugs

2011 ◽  
Vol 287-290 ◽  
pp. 1509-1512 ◽  
Author(s):  
Cheng Wu Li ◽  
Gang Li ◽  
Ji Cheng Zuo
Keyword(s):  
Molecular Weight ◽  
Polyethylene Glycol ◽  
Water Solubility ◽  
Uv Spectroscopy ◽  
Chloroacetic Acid ◽  
Synthesis And Characterization ◽  
Drug Release Rate ◽  
H Nmr ◽  
Ft Ir

A series of novel polyethylene glycol derivates was synthesized by esterification of chloroacetic acid with polyethylene glycol.The PEG-5-FU conjugates were characterized by FT-IR,1H-NMR and UV spectroscopy. The result showed that 5-FU was successfully connected to the ends of PEG ester. Drug content of PEG2000-5-FU conjugate achieved 17.4%. As the molecular weight of PEG increased, the water solubility of prodrugs improved. When the molecular weight of PEG reached 2000, the conjugate had the best water solubility and the highest drug release rate.

scholarly journals SINTESIS DAN KAREKTERISASI SENYAWA KIRAL HASIL REAKSI ANTARA METILEUGENOL KASAR DENGAN ASAM ASETAT

KOVALEN ◽  
2016 ◽  
Vol 2 (3) ◽  
Author(s):  
Muh. Hajir S. Lasapo ◽  
Erwin Abdul Rahim ◽  
Ruslan Ruslan ◽  
Indriani Indriani
Keyword(s):  
Molecular Weight ◽  
Acetic Acid ◽  
Chemical Compound ◽  
Reaction Process ◽  
Synthesis And Characterization ◽  
Chiral Compounds ◽  
Ft Ir

The research about synthesis and characterization of chiral compounds from the rough methyleugenol with acetic acid as the catalyst has been done. The goal is to determine the  content of 1-(3,4-dimetoksifenil)-2-propanil acetate compound which is produced in the reaction process of metileugenol with acetic acid and to characterizased the chemical compound of the product. The results showed that the content of 1-(3,4-dimetoksifenil)-2-propanil acetate compound that has been obtained was  45.87% with a molecular weight of 238.Keywords : Methyleugenol, Chiral, FT-IR, GC-MS

Synthesis and characterization of high molecular weight phthalocyanine-PPV copolymers through post-polymerization functionalization

2011 ◽  
Vol 15 (07n08) ◽  
pp. 659-666 ◽  
Author(s):  
Juan-José Cid ◽  
Jan Duchateau ◽  
Ineke Van Severen ◽  
Carolina R. Ganivet ◽  
Gema de la Torre ◽  
...  
Keyword(s):  
Molecular Weight ◽  
High Molecular Weight ◽  
Soluble Fraction ◽  
Synthesis And Characterization ◽  
H Nmr ◽  
Ft Ir ◽  
Copolymer 1 ◽  
High Molecular Weight Poly

High molecular weight poly(p-phenylenenevinylene) PPV copolymers laterally substituted with zinc (II) phthalocyanines ( Zn(II)Pc -PPV 1 and 2) have been synthesized by means of post-polymerization functionalization reactions through DCC-mediated esterifications between hydroxy-phthalocyanines 4 and 6 and carboxy-bearer PPV copolymers, comprising 2-methoxy-5-(3,7-dimethyloctyloxy)-1,4-phenylenevinylene (MDMO-PPV) and 1,4-(2-(5-carboxypentyloxy)-5-methoxyphenylenevinylene (CPM-PPV) units in a 9:1 (3) and 1:1 (5) ratio, respectively. The resulting copolymer 1 contains a 7 mol % of Pc molecules, while copolymer 2, which is isolated as the soluble fraction of the reaction with the starting 1:1 copolymer (namely having around 50% of COOH -containing monomeric units), holds a 9 mol % of zinc(II) phthalocyanines. 1 and 2 were fully characterized by 1H NMR, UV-vis and FT-IR spectroscopies.

scholarly journals Synthesis and characterization of different soybean oil-based polyols with fatty alcohol and aromatic alcohol

e-Polymers ◽  
2021 ◽  
Vol 21 (1) ◽  
pp. 491-499
Author(s):  
Fukai Yang ◽  
Hao Yu ◽  
Yuyuan Deng ◽  
Xinyu Xu
Keyword(s):  
Molecular Weight ◽  
Soybean Oil ◽  
Retention Time ◽  
Ring Opening ◽  
Isoamyl Alcohol ◽  
Synthesis And Characterization ◽  
Intermolecular Force ◽  
H Nmr ◽  
Epoxy Groups

Abstract In this article, five kinds of soybean oil-based polyols (polyol-E, polyol-P, polyol-I, polyol-B, and polyol-M) were prepared by ring-opening the epoxy groups in epoxidized soybean oil (ESO) with ethyl alcohol, 1-pentanol, isoamyl alcohol, p-tert-butylphenol, and 4-methoxyphenol in the presence of tetrafluoroboric acid as the catalyst. The SOPs were characterized by FTIR, 1H NMR, GPC, viscosity, and hydroxyl numbers. Compared with ESO, the retention time of SOPs is shortened, indicating that the molecular weight of SOPs is increased. The structure of different monomers can significantly affect the hydroxyl numbers of SOPs. Due to the large steric hindrance of isoamyl alcohol, p-hydroxyanisole, and p-tert-butylphenol, SOPs prepared by these three monomers often undergo further dehydration to ether reactions, which consumes the hydroxyl of polyols, thus forming dimers and multimers; therefore, the hydroxyl numbers are much lower than polyol-E and polyol-P. The viscosity of polyol-E and polyol-P is much lower than that of polyol-I, polyol-B, and polyol-M. A longer distance between the molecules and the smaller intermolecular force makes the SOPs dehydrate to ether again. This generates dimer or polymers and makes the viscosity of these SOPs larger, and the molecular weight greatly increases.

Synthesis and Characterization of Tris(trimethyltin) Thiophosphate (Me3Sn)3PO3S

1993 ◽  
Vol 48 (12) ◽  
pp. 1781-1783 ◽  
Author(s):  
Abdel-Fattah Shihada
Keyword(s):  
Aqueous Medium ◽  
Raman Spectra ◽  
Mass Spectra ◽  
Ir And Raman Spectra ◽  
Synthesis And Characterization ◽  
Polymeric Structure ◽  
Ir And Raman

(Me3Sn)3PO3S has been prepared from the reaction of Me3SnCl with Na3PO3S • 12 H2O under cooling in aqueous medium. Its IR and Raman spectra are found to be consistent with a polymeric structure with tetra- and penta-coordinated tin atoms. The 31P NMR and mass spectra of (Me3Sn)3PO3S are reported and discussed.

One Step Synthesis and Characterization of Zirconia-Graphene Composites

2012 ◽  
Vol 600 ◽  
pp. 174-177 ◽  
Author(s):  
Jian Fei Xia ◽  
Zong Hua Wang ◽  
Yan Zhi Xia ◽  
Fei Fei Zhang ◽  
Fu Qiang Zhu ◽  
...  
Keyword(s):  
Synthesis And Characterization ◽  
Two Dimensional ◽  
X Ray Diffraction ◽  
X Ray ◽  
Graphene Composite ◽  
Transmission Electron ◽  
One Step ◽  
Ft Ir ◽  
Xrd Techniques

Zirconia-graphene composite (ZrO2-G) has been successfully synthesized via decomposition of ZrOCl2•6H2O in a water-isopropanol system with dispersed graphene oxide (GO) utilizing Na2S as a precursor could enable the occurrence of the deposition of Zr4+ and the deoxygenation of GO at the same time. Transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FT-IR) and X-ray diffraction (XRD) techniques were used to characterize the samples. It was found that graphene were fully coated with ZrO2, and the ZrO2 existing in tetragonal phase, which resulted in the formation of two-dimensional composite.

Synthesis and Characterization of Poly(Aryl Ether Quinoxaline)s with Controlled Molecular Weight

2011 ◽  
Vol 391-392 ◽  
pp. 826-829
Author(s):  
Song Ya Zhang ◽  
Zhong Xiao Li ◽  
Jia Ling Pu
Keyword(s):  
Molecular Weight ◽  
Glass Transition ◽  
Strong Acid ◽  
Decomposition Temperature ◽  
Molar Ratio ◽  
Synthesis And Characterization ◽  
Aryl Ether ◽  
Good Solubility ◽  
Step Procedure

Novel poly(aryl ether quinoxaline)s (PEQs) were prepared via a two-step procedure. First, poly (ether benzil) (PEB) was synthesized by the polycondensation of 4,4’-difluorobenzil and 4,4’-isopropylidenediphenol.Then, PEB was reacted with 1,2-diaminobenzene and 4,4'-oxydibenzene-1,2-diamine to give the PEQs. The molecular weight of the PEQs could be adjusted easily by varying the molar ratio of 1,2-diaminobenzene to 4,4'-oxydibenzene-1,2-diamine. The PEQs exhibited good solubility in common organic solvents such as NMP, DMAc, DMF, cyclohexanone and chloroform. In addition, the PEQs also had high glass transition (Tg) temperatures and good thermal properties, with an initial thermal decomposition temperature above 475 oC and glass transition temperatures above 210 oC. They also exhibited excellent resistance to strong acid and alkali.

ATRP Synthesis and Characterization of μ,αω-allyl-terminated Macromonomers as Precursors for End-linked Gels and Hydrogels

2003 ◽  
Vol 774 ◽  
Author(s):  
Lucy Vojtova ◽  
Nicholas J. Turro ◽  
Jeffrey T. Koberstein
Keyword(s):  
Molecular Weight ◽  
Monomer Concentration ◽  
Monomer Conversion ◽  
Catalyst System ◽  
Linear Increase ◽  
Butyl Methacrylate ◽  
First Order Kinetics ◽  
Significant Difference ◽  
Ft Ir

AbstractSynthesis of α,ω-allyl-terminated telechelic macromonomers based on poly(tert-butyl methacrylate) (poly(t-BMA)) and poly(methacrylic acid) (poly(MAA)) was studied with the aim of preparing end-linked gels and hydrogels. Low molecular weight α-allyl-terminated poly(t-BMA) macromonomers with narrow polydispersities (Mw/Mn = 1.16) were synthesized via controlled atom transfer radical polymerization (ATRP) using a Cu(I)Br/N,N,N',N',N',N'-hexamethyltriethylenetetraamine catalyst system in conjunction with an allyl-2-bromoisobutyrate as the functional initiator. The polymerizations exhibited a linear increase of molecular weight in direct proportion to the monomer conversion and first-order kinetics with respect to monomer concentration. No significant difference was found between using polar or non-polar solvents (tetrahydrofuran or benzene, respectively). Optimization of reaction conditions to obtain the highest degree of active terminal bromine is discussed. Quenching the ATRP reaction with allyltributyltin yielded α,ω-allyl-terminated poly(t-BMA) macromonomers by replacing the terminal bromine with ω-allyl functional group. Poly(MAA) macromonomers were prepared by deprotection of the tert-butyl group from α,ω-allyl-terminated poly(t-BMA) macromonomers using concentrated trifluoroacetic acid at room temperature. Successful synthetic steps were confirmed by 1H NMR, FT-IR and MALDI-TOF MS analyses. The α,ω-allyl-terminated macromonomers were proven to be candidates for further polymerization by forming end-linked, non-soluble gels.

Electrochemically Synthesis and Characterization of Copolymers Based on 1, 4-Diethoxybenzene and 3, 4-Ethylenedioxythiophene

2011 ◽  
Vol 335-336 ◽  
pp. 989-993
Author(s):  
Mi Ouyang ◽  
Zhen Wei Yu ◽  
Yi Xu ◽  
Yu Jian Zhang ◽  
Cheng Zhang
Keyword(s):  
Cyclic Voltammetry ◽  
Ir Spectroscopy ◽  
Feed Ratio ◽  
Synthesis And Characterization ◽  
Monomer Mixture ◽  
Long Wavelength ◽  
H Nmr ◽  
Ft Ir ◽  
Ft Ir Spectroscopy

Copolymers based on 1, 4-diethoxybenzene (DEB) and 3, 4-ethylenedioxythiophene (EDOT) were electrochemically synthesized and characterized. The structures of the copolymers were established by 1H NMR and FT-IR spectroscopy. The results indicated the final product was a copolymer instead of a blend or a composite. The physical properties were systematically investigated by cyclic voltammetry, UV-vis absorption and fluorescence. The PL maximum of copolymers presented obviously red-shift to long wavelength as the feed ratio of EDOT in monomer mixture increased.

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