Analisis Fitokimia Air Rebusan Daun Mantalalu (Euphorbia hirta L) Asal Kota Palu Provinsi Sulawesi Tengah

One of the herbal plants that have long been used as traditional herbal medicine by Central Sulawesi peoples is Mantalalu (Euphorbia hirta L). Central Sulawesi peoples used this Mantalalu to appendicitis medicine. The chemical compound contained in Mantalalu plant has a role in providing different pharmacology. A study was conducted about the chemical compound content Mantalalu plant (Euphorbia hirta L). The method of this research was boiling dried leave and wet leave of Mantalalu plant and phytochemical test including flavonoids tests, alkaloids tests, saponins tests, polyphenol, and tannin tests. The results of this research showed that the decoction of dried and wet leaf samples of Mantalalu plant contained flavonoid, polyphenol, tannin, and saponins bioactive compounds.

POTENSI DAUN KATUK SEBAGAI PENURUN KADAR LEMAK PADA PRODUK UNGGAS MELALUI SKRINING FITOKIMIA

Katuk leaves are known as vegetables that are rich in nutrients in several regions in Indonesia. In addition, it has the potential as an herbal medicine that needs to be developed based on its chemical compound content. The groups of chemical compounds contained in plants can be analyzed using a phytochemical screening test. Phytochemical screening was carried out on katuk leaf extract samples obtained through the maceration method using methanol solvent which was then concentrated using a rotary evaporator. Phytochemical screening test consisted of phenolic, tannin, flavonoid, saponin, triterpenoid, steroid, and alkaloid screening. Furthermore, the test results will be used as a basis for researchers in developing the potential of katuk leaves as herbs to reduce fat content in poultry product. The class of compounds, especially flavonoids, saponins, and tannins has a role in reducing fat accumulation. The test results showed that the positive katuk leaf extract contained moderate amounts of phenolic compounds, tannin, flavonoids, saponins, triterpenoids, and alkaloids. That is, katuk leaves have the potential as an herb that can reduce fat levels in poultry products.

Identifikasi Karbon Monoksida Dalam Darah Pada Penjual Buah Di Jembatan Kembar Sungguminasa

The chemical compound of CO gas is a gas that has no color and contributes greatly to environmental pollution as a result of incomplete combustion of fuel produced from motor vehicles. Carbon monoxide is very dangerous (toxic, so it is often referred to as the "silent killer". The presence of CO gas will be very dangerous if inhaled by humans because the gas will replace the position of oxygen that binds to hemoglobin in the blood. The purpose of the study was to identify the presence or absence of carbon monoxide (CO) in the blood of fruit sellers at the Sungguminasa Twin Bridge. This research is an analytical observational field research using the alkaline dilution test method. The sampling technique used purposive sampling with the criteria of working more than one year, working 8 hours a day and not smoking. The number of samples used as many as 9 samples of venous blood. From the results of this study, it can be concluded that the presence of carbon monoxide gas was not identified in all blood samples of fruit sellers at the Sungguminasa Twin Bridge. This is because in the alkaline dilution test method, CO gas can only be identified with saturation levels above 20%.

Elemental Analysis Using Atomic Absorption Spectroscopy

The resonance radiation study is a powerful means in obtaining valuable information concerning the behavior of individual atoms and molecules. Various quantitative techniques are available in order to determine the amount of analyte and analysis of trace elements in the sample. Some technique uses the principle, when the number of atoms in the path of light increases, the amount of light absorption increases. While other techniques use dissociation of chemical compound free atoms by supplying enough thermal energy. In this paper, an attempt is made to compare various analytical methods with their merits and demerits and the reasons for popularity of atomic absorption spectroscopy among researchers. Elemental analysis using atomic absorption spectroscopy of various elements that are found in nature particularly in foods and environment is also presented.

On Computation Degree-Based Topological Descriptors for Planar Octahedron Networks

A molecular graph is used to represent a chemical molecule in chemical graph theory, which is a branch of graph theory. A graph is considered to be linked if there is at least one link between its vertices. A topological index is a number that describes a graph’s topology. Cheminformatics is a relatively young discipline that brings together the field of sciences. Cheminformatics helps in establishing QSAR and QSPR models to find the characteristics of the chemical compound. We compute the first and second modified K-Banhatti indices, harmonic K-Banhatti index, symmetric division index, augmented Zagreb index, and inverse sum index and also provide the numerical results.

Anti-inflammatory potential of λ-carrageenan by inhibition of IL-6 receptor: in silico study

In some cases, the immune system in COVID-19 patients leads to the release of excess cytokine production (cytokine storm), which will potentially develop into pneumonia. Interleukin 6 (IL-6) plays the role of pro-inflammatory cytokine, it is a receptor mediated signalling system. Macroalgae is well known as a source of valuable bioactive substances with potential biological activities. Among them is the sulphated polysaccharide lambda-carrageenan λ-CGN which has been reported as an anti-inflammatory agent. However, its mechanism of action against IL-6 production is currently unknown. This study aims to predict potential molecular mechanisms of λ-CGN chemical compound against IL-6 expression through in silico study. Chemical compound of λ-CGN and target protein in this study were obtained from the pubchem and protein data bank (PDB). The molecular docking prediction was conducted with PyRx software, the result is λ-CGN compound showing strong binding energy to bind target protein IL-6 receptor with the value of -5.9 kcal/mol. Based on the results of in silico study, the sulphated polysaccharide λ-CGN potentially inhibits IL-6R expression by binding ligand pocket with six conventional hydrogen bonds (amino acid residus: His256, His 257, Trp 219, Arg 231, and Asp 221) and two carbon hydrogen bonds (amino acid residus: THR 218 and GLN 220). Binding with these amino acid residues potentially contributes to IL-6 receptor structural change which could result in functional change. Hence, further studies related to in vitro and in vivo investigations would be interesting to further understand the inhibitory mechanism of λ-CGN against IL-6.

The Effect of Some Chemical Compounds and Plants Water Extracts on Inhibiting The Nitrification in The Soil and Wheat (Triticum Aestivuim L.) Growth and Yield

A field experiment was carried out in Dhi Qar Governorate, Al-Fadhliya region, for season of 2018-2019. Chemical compounds DMPP, DCD, and ATS as well as aqueous extracts of capers seeds and palm bast, were added to inhibiting the nitrification in the soil, and some of the growth characteristics of the wheat. Three of nitrogen level were added as urea (46% N) fertilizer (100, 150 and 200 kg N per ha). Aqueous extracts of plants were added to the urea fertilizer at a concentration of 100 ml for each kg of fertilizer. The experiment designed used RCBD with three replications. Wheat seeds were sown at 11/15/2018. Soil samples were Collecting from the soil (0-30) cm during the growing season after (10, 20, 40 and 60) days after the fertilization. The amount of ammonium, nitrate and nitrite, were estimated. The results showed that the fertilizer level 150 kg N ha−1 with all extracts and chemical compound treatments were exceeded compared with 200 kg N ha−1 without treatments.

The Effect of Pyrrolidinium Bromide Salt in The Life of The Southern Cowpea Beetle Callosobruchus Maculatus (Fab) (Coleoptera: Chrysomelidae)

The study aimed to evaluate the efficacy test of a chemical compound (pyrrolidinium bis - bromide salt) laboratory-prepared in the life of the southern cowpea beetle Callosobruchus maculatus, which is one of the most important pulses stored pest. The compound N1 was prepared and the structure was proved using1H NMR, IR technique. For treating the seeds out, three concentrations from N1, 500, 1500, 3000 ppm, were prepared. The results showed that the compound outperformed the percentage of repellent (prevention of laying eggs), with the concentration of 500 ppm registered the lowest number of eggs laid, with 96.67 eggs and an repellent rate of 53.97 %, compared to 210.00 eggs. While the results showed a significant effect when the concentration increased. This caused a 66.32 % drop in first-generation personnel from the highest rate of 95.00. The higher concentration also showed the lowest productivity compared with the rest of the concentrations, at 21.05 % compared to controlling sample 45.45%, and had no significant effect on increasing the duration of the pupal stage by 7.83 days compared to 7.50 days. Compared to 7.50 days of control, it affected the increase in the 7.50-day period of the larvae stage compared to the control of 5.50 days. The 1500 ppm concentration did not affect the vitality of the seeds after being treated as they were not significantly different from control. The results also showed that not all of the compound's concentrations had a repellent effect against the southern cowpea beetle.

A study on physical characteristics of dried bio-slurry produced in tropical condition through treatment combination of drying and turning period

The research aims to evaluate the physical characteristics of dried bio-slurry produced by treatment combination of drying and turning period in tropical conditions. Research material used fixed-dome digester model with a capacity of 12 m3 and cattle dung from Simmental crossbreed. Physical characteristics of bio-slurry were obtained by combining treatments between drying period (15 and 30 days) and turning period (each turning process in 7 and 10th day) as follows: T1 (15 days and 7th day), T2 (15 days and 10th day), T3 (30 days and 7th day), T4 (30 days and 10th day). The chemical compound of fresh bio-slurry was analyzed as initial information. The humidity, temperature, and color data were analyzed using analysis of variance and further analyzed using Tukey’s test. Also, the chemical compound and pH used descriptive analysis. The study obtained that the chemical composition of fresh bio-slurry was moisture content (89.53%), C-organic (37.27%), nitrogen (48.92ppm), phosphor (1.71%), potassium (3.89%), and C/N ratio (7.454). Besides, the treatment showed a significant difference (P<0.01) in humidity and color. Temperature dan pH of dried bio-slurry remained constant at 29.10-29.270C and 7 respectively. Therefore, treatment combinations can be applied to make dried bio-slurry as fertilizer in tropical conditions.

Red-Fleshed Apple Anthocyanin Extract Reduces Furan Content in Ground Coffee, Maillard Model System, and Not-from-Concentrate Apple Juice

Furan is a volatile and carcinogenic heterocyclic chemical compound that occurs in a wide range of thermally processed food. It can be induced during food-preparing processes by high temperatures and UV-C light. In the present study, the degradation of furan content in ground coffee, Maillard model system, and not-from-concentrate (NFC) apple juice by red-fleshed apple anthocyanin extract (RAAE) was studied. The results demonstrated that RAAEs had different degrees of degradation of furan content in coffee powder, and the RAAE from ‘XJ3’ had the most significant effect, with a reduction rate of up to 20%. Moreover, by adding RAAE to the Maillard model system, we found the amounts of furan were significantly reduced. At the same time, RAAE from ‘XJ3’ could observably reduce the content of furan in pasteurized NFC juice, with ‘Fuli’ NFC juice furan content decreasing the most, which was 68%. Taken together, our study demonstrated that the use of RAAE could be a feasible way to reduce furan content in ground coffee, Maillard model system, and NFC apple juice.