scholarly journals Role of nanocurcumin on experimentally induced alpha-amanitin toxicity in rats

2021 ◽  
Vol 10 (11S) ◽  
pp. 799-806
Author(s):  
Khumtya Debbarma ◽  
Jadav Sarma ◽  
Rohini Kumar Roy ◽  
Himangshu Baruah ◽  
Biswajit Dutta
Keyword(s):  
Alpha Amanitin ◽  
Experimentally Induced

Experimental Amyloidosis Induced by Immune Complex

1971 ◽  
Vol 29 ◽  
pp. 582-583
Author(s):  
A. Kawaoi
Keyword(s):  
Immune Complex ◽  
Systemic Amyloidosis ◽  
Human Diseases ◽  
Experimental Amyloidosis ◽  
Freund’S Complete Adjuvant ◽  
Freund's Complete Adjuvant ◽  
Immunological Approach ◽  
Experimentally Induced

Numbers of immunological approach have been made to the amyloidosis through the variety of predisposing human diseases and the experimentally induced animals by the greater number of agents. The results suggest an important role of impaired immunity involving both humoral and cell-mediated aspects.Recently the author has succeeded in producing amyloidosis in the rabbits and mice by the injections of immune complex of heat denatured DNA.The aim of this report is to demonstrate the details of the ultrastructure of the amyloidosis induced by heterologous insoluble immune complex. Eleven of twelve mice, dd strain, subcutaneously injected twice a week with Freund's complete adjuvant and four of seven animals intraperitonially injected developed systemic amyloidosis two months later from the initial injections. The spleens were electron microscopically observed.

EXPRESS: The Effects of Experimentally Induced Emotions on Revising Common Vaccine Misconceptions

2021 ◽  
pp. 174702182110178
Author(s):  
Greg Trevors ◽  
Catherine Bohn-Gettler ◽  
Panayiota Kendeou
Keyword(s):  
Cognitive Processes ◽  
Positive Emotions ◽  
Educational Practice ◽  
Empirical Knowledge ◽  
Emotion Induction ◽  
Correct Information ◽  
Knowledge Revision ◽  
Refutation Texts ◽  
Experimentally Induced

Knowledge revision is the process of updating incorrect prior knowledge in light of new, correct information. Although theoretical and empirical knowledge has advanced regarding the cognitive processes involved in revision, less is known about the role of emotions, which have shown inconsistent relations with key revision processes. The present study examined the effects of experimentally induced emotions on online and offline knowledge revision of vaccination misconceptions. Before reading refutation and non-refutation texts, 96 individuals received either a positive, negative, or no emotion induction. Findings showed that negative emotions, more than positive emotions, resulted in enhanced knowledge revision as indicated by greater ease of integrating correct information during reading and higher comprehension test scores after reading. Findings are discussed with respect to contemporary frameworks of knowledge revision and emotion in reading comprehension and implications for educational practice.

Role of Aspirin and Dexamethasone against Experimentally Induced Depression in Rats

2016 ◽  
Vol 119 (1) ◽  
pp. 10-18 ◽  
Author(s):  
Shailendra Bhatt ◽  
Priyanka Shukla ◽  
Jibril Raval ◽  
Sunita Goswami
Keyword(s):  
Experimentally Induced

scholarly journals Genetic Evidence for an Essential Role of Neuronally Expressed IL-6 Signal Transducer gp130 in the Induction and Maintenance of Experimentally Induced Mechanical Hypersensitivityin vivoandin vitro

2011 ◽  
Vol 7 ◽  
pp. 1744-8069-7-73 ◽  
Author(s):  
Serena Quarta ◽  
Christian Vogl ◽  
Cristina E Constantin ◽  
Nurcan Üçeyler ◽  
Claudia Sommer ◽  
...  
Keyword(s):  
Essential Role ◽  
Genetic Evidence ◽  
Signal Transducer ◽  
Experimentally Induced

scholarly journals The Possible Role of Mesenchymal Stem Cells Therapy in the Repair of Experimentally Induced Colitis in Male Albino Rats

2013 ◽  
Vol 6 (2) ◽  
pp. 92-103 ◽  
Author(s):  
Sohair Ahmed Fawzy ◽  
Rahma Kamal El-din Abo-Elnou ◽  
Dalia Fathy Abd-El-Maksoud El-Deeb ◽  
Marwa Mohamed Yousry Abd-Elkader
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Albino Rats ◽  
Stem Cells Therapy ◽  
Experimentally Induced

scholarly journals Roles of gene transcription and PKA subtype activation in maturation of murine oocytes

Reproduction ◽  
2002 ◽  
pp. 799-806 ◽  
Author(s):  
KF Rodriguez ◽  
RM Petters ◽  
AE Crosier ◽  
CE Farin
Keyword(s):  
Gene Transcription ◽  
Cumulus Cell ◽  
Cumulus Cells ◽  
Type I ◽  
Type Ii ◽  
Germinal Vesicle Breakdown ◽  
Series Of Experiments ◽  
And Control ◽  
Alpha Amanitin

The aims of this study were to examine the role of transcription and the coincident involvement of type I and type II protein kinase A (PKA) in the resumption of meiosis in murine cumulus-oocyte complexes (COCs) using the transcriptional inhibitors 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole (DRB) and alpha-amanitin. The first series of experiments was designed to: (i) characterize the role of transcription in gonadotrophin-mediated and spontaneous maturation of murine oocytes; (ii) examine the roles of specific gonadotrophins (FSH versus hCG) and cumulus cells in transcriptionally mediated oocyte maturation; and (iii) determine the reversibility of the transcriptional arrest of meiosis. In the presence of FSH, transcriptional inhibitors arrested germinal vesicle breakdown (GVBD) (DRB: 2 +/- 2% and control: 76 +/- 2%; alpha-amanitin: 4 +/- 4% and control: 70 +/- 4%). Furthermore, cumulus cells were required for transcriptional inhibitors to arrest GVBD (DRB with cumulus cells: 0 +/- 15%; DRB without cumulus cells: 94 +/- 13%; alpha-amanitin with cumulus cells: 15 +/- 2%; alpha-amanitin without cumulus cells: 99 +/- 2%). Thus, in mice, FSH-mediated GVBD uses a transcriptional mechanism, which probably occurs within the cumulus cell compartment. In a second series of experiments, the role of transcription in mediating the resumption of meiosis after activation of either type I or type II PKA was examined. Activation of type I PKA in murine COCs resulted in an arrest of GVBD that was independent of a transcriptional event (with DRB: 7 +/- 9% GVBD; without DRB: 11 +/- 9% GVBD). In contrast, activation of type II PKA resulted in a resumption of meiosis, which required the occurrence of gene transcription (with DRB: 12 +/- 9% GVBD; without DRB: 80 +/- 9% GVBD). As FSH binding to cumulus cells activates the PKA second messenger system, our results indicate that, in cultured murine COCs, FSH binding to cumulus cells results in the activation of type II PKA, which, in turn, mediates a downstream transcriptional event required for the initiation of GVBD.

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