scholarly journals Differential Diagnosis and Surgical Management of Cerebellopontine Angle Cystic Lesions

2018 ◽  
Vol 22 (3) ◽  
pp. 110-115
Author(s):  
Tobias Alécio Mattei ◽  
Carlos R. Goulart ◽  
Julia Schemes De Lima ◽  
Ricardo Ramina
Keyword(s):  
Differential Diagnosis ◽  
Critical Review ◽  
Cerebellopontine Angle ◽  
Careful Consideration ◽  
Preoperative Imaging ◽  
Cystic Lesions ◽  
Diagnostic Challenge ◽  
Imaging Evaluation ◽  
Wide Range ◽  
Cystic Meningiomas

Cerebellopontine angle (CPA) tumors in adults are mainly  benign and extra-axial. Although the most common CPA lesion (vestibular schwannoma) is familiar to most neurosurgeons, cystic lesions of the CPA do pose an important diagnostic challenge demanding a careful consideration of a wide range of differential diagnosis including: epidermoid cysts, arachnoid cysts, cystic schwannomas, cystic meningiomas as well as other rare entities such as vascular and malignant tumoral lesions. The authors present a critical review of the current literature on cystic CPA lesions, providing an overview about possible differentials as well as guidelines for preoperative imaging evaluation of a cystic CPA lesion. 

scholarly journals A Challenging Case of Metastatic Intra-Abdominal Synovial Sarcoma with Unusual Immunophenotype and Its Differential Diagnosis

2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
Yi-Che Changchien ◽  
Uhrin Katalin ◽  
János Fillinger ◽  
László Fónyad ◽  
Gergő Papp ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Tumor Cells ◽  
Synovial Sarcoma ◽  
Desmoid Tumor ◽  
Gold Standard ◽  
Fusion Gene ◽  
Rt Pcr ◽  
Diagnostic Challenge ◽  
Wide Range ◽  
Typical Morphology

The primary and metastatic gastrointestinal synovial sarcoma is rare with a wide differential diagnosis. It usually expresses cytokeratins EMA, BCL2 with an occasional CD99, and S100 positivity but not desmin. We present a case of metastatic synovial sarcoma with unusual immunophenotype causing diagnostic challenges. The tumor cells showed focal cytokeratin, EMA, and, unexpectedly, desmin positivity. Additional intranuclear TLE-1 positivity and negativity for CD34 and DOG-1 were also identified. A diagnosis of monophasic synovial sarcoma was confirmed by using FISH break-apart probe. RT-PCR revealed the SYT-SSX1 fusion gene. Intra-abdominal synovial sarcoma, either primary or metastatic, with unusual desmin positivity raises the diagnostic challenge, since a wide range of differential diagnoses could show a similar immunophenotype (leiomyosarcoma, desmoid tumor, myofibroblastic tumor, and rarely GIST etc.). Typical morphology and focal cytokeratin/EMA positivity should alert to this tumor, and FISH and RT-PCR remain the gold standard for the confirmation.

scholarly journals A case of chronic ulcer due to subcutaneous arteriolosclerosis in an obese patient mimicking pyoderma gangrenosum

2018 ◽  
Vol 10 (1) ◽  
Author(s):  
Sezin Fıçıcıoğlu ◽  
Nuray Can ◽  
Busem Tutuğ
Keyword(s):  
Morbid Obesity ◽  
Differential Diagnosis ◽  
Renal Insufficiency ◽  
Pyoderma Gangrenosum ◽  
Tissue Perfusion ◽  
Chronic Ulcer ◽  
Diagnostic Challenge ◽  
Wide Range ◽  
Chronic Ulcers ◽  
Arteriolar Narrowing

The differential diagnosis of chronic ulcers covers a wide range of diseases and poses a diagnostic challenge. Subcutaneous ischemic arteriolosclerosis can lead to local ischaemia and ulceration as a result of arteriolar narrowing and reduction of tissue perfusion. This pathophysiological feature can be seen in eutrophication (nonuremic calciphylaxis) in morbid obesity, hypertensive ischemic leg ulcer (Martorell ulcer) and calciphylaxis in chronic renal insufficiency. All of the ulcers happened in this way can be wrongly diagnosed as pyoderma gangrenosum because of clinical similarity and inadequate biopsies. We report a case of chronic ulcer due to subcutaneous arteriolosclerosis in morbid obesity, wrongly diagnosed as pyoderma gangrenosum. It can be detrimental to misdiagnose the ulcers due to subcutaneous arteriolosclerosis as pyoderma gangrenosum since they need a diametrically different approach.

Contribution of MR imaging and CEA cystic fluid level to the differential diagnosis of cystic lesions of the pancreas

2001 ◽  
Vol 120 (5) ◽  
pp. A764-A764
Author(s):  
M DELHAYE ◽  
C WINANT ◽  
D DEGRE ◽  
B GULBIS ◽  
C GERVY ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Mr Imaging ◽  
Cystic Lesions ◽  
Fluid Level ◽  
Cystic Fluid

DIAGNOSTIC VALUE OF SPECIFIC ANTIBODY SYNTHESIS IN BRAIN OF PATIENTS WITH NEUROINFECTIONS

2019 ◽  
Vol 72 (8) ◽  
pp. 1437-1441
Author(s):  
Pavel Dyachenko ◽  
Igor Filchakov ◽  
Anatoly Dyachenko ◽  
Victoria Kurhanskaya
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Clinical Manifestations ◽  
Diagnostic Value ◽  
Diagnostic Challenge ◽  
Specific Antibodies ◽  
Intrathecal Synthesis ◽  
Varicella Zoster ◽  
Mrz Reaction ◽  
Wide Range

Introduction: Viral encephalitis accounts for 40-70% of all cases worldwide, central nervous system infections pose a diagnostic challenge because clinical manifestations are not typically pathognomonic for specific pathogens, and a wide range of agents can be causative. The aim: To assess the diagnostic value of intrathecal synthesis of specific antibodies in patients with inflammatory lesions of the central nervous system. Materials and methods: Within the framework of the study, two groups of 90 people in each were formed from the patients with neuroinfections admitted to our Center. Intrathecal synthesis (ITS) of total (unspecific) IgG in members of one of group (group of compare) was determined. Brain synthesis of specific antibodies (Ab) to some neurotropic pathogens (herpes simplex virus 1/2, cytomegalovirus, Epstein-Barr virus, varicella zoster virus, rubella virus, Borrelies) was studied in the second group of patients (group of interest). There were no statistically significant differences between groups by gender and age. Encephalitis and encephalomyelitis prevailed among patients of both groups Results: ITS of total IgG was established in 30 (33.3 ± 6.1 %) patients of the first group with IgG index more than 0.6 indicating on inflammatory process in CNS and no marked changes of CSF. ITS of specific Ab was determined in 23 of 90 (25.6 ± 4.6 %) patients included into group of interest. In more than half of cases Ab to several infectious agents were detected simultaneously. ITS of various specificity, in particular, to measles and rubella viruses, and VZV, known as MRZ-reaction, is characteristic of some autoimmune lesions of CNS, multiple sclerosis first of all. In fact, further research of 5 patients with MRZ-reaction confirmed their autoimmune failure of CNS. Detection of ITS in the CSF samples didn’t depend on concentration of specific Ab in serum and CSF and wasn’t followed by HEB dysfunctions which were observed with the same frequency in patients with or without ITS (13.0 % and 13.6 % respectively). Conclusion: Specific Ab synthesis to several neurotropic pathogens in the CSF of significant part of examined patients was established. Thus, diagnostic value of ITS of specific immunoglobulins seems to be limited to cases in which autoimmune damage of the CNS is suspected.

scholarly journals Gastric Schwannoma: A Rare but Important Differential Diagnosis of a Gastric Submucosal Mass

2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
William Yoon ◽  
Kari Paulson ◽  
Paul Mazzara ◽  
Sweety Nagori ◽  
Mohammed Barawi ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Surgical Resection ◽  
Treatment Options ◽  
Partial Gastrectomy ◽  
Preoperative Imaging ◽  
Mesenchymal Tumors ◽  
Gastric Schwannoma ◽  
Gastric Mass ◽  
Submucosal Mass ◽  
Slow Growing

Schwannomas are generally slow growing asymptomatic neoplasms that rarely occur in the GI tract. However, if found, the most common site is the stomach. Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract, and 60–70% of them occur in the stomach. Owing to their typical presentation as submucosal neoplasms, gastric schwannomas and GISTs appear grossly similar. Accordingly, the differential diagnosis for a gastric submucosal mass should include gastric schwannomas. Furthermore, GI schwannomas are benign neoplasms with excellent prognosis after surgical resection, whereas 10–30% of GISTs have malignant behavior. Hence, it is important to distinguish gastric schwannomas from GISTs to make an accurate diagnosis to optimally guide treatment options. Nevertheless, owing to the paucity of gastric schwannomas, the index of suspicion for this diagnosis is low. We report a rare case of gastric schwannoma in 53-year-old woman who underwent laparoscopic partial gastrectomy under the suspicion of a GIST preoperatively but confirmed to have a gastric schwannoma postoperatively. This case underscores the importance of including gastric schwannomas in the differential diagnosis when preoperative imaging studies reveal a submucosal, exophytic gastric mass. For a gastric schwannoma, complete margin negative surgical resection is the curative treatment of choice.

Cyst Fluid Cytologic Analysis in the Differential Diagnosis of Pancreatic Cystic Lesions

1994 ◽  
Vol 101 (4) ◽  
pp. 483-487 ◽  
Author(s):  
Barbara A. Centeno ◽  
Kent B. Lewandrowski ◽  
Andrew L. Warshaw ◽  
Carolyn C. Compton ◽  
James F. Southern
Keyword(s):  
Differential Diagnosis ◽  
Cyst Fluid ◽  
Cystic Lesions ◽  
Cytologic Analysis

Implementation of Shape Memory Alloys as Active Elements in Injuries Recuperative Equipment

2014 ◽  
Vol 657 ◽  
pp. 392-396
Author(s):  
Adela Ursanu Dragoş ◽  
Sergiu Stanciu ◽  
Nicanor Cimpoeşu ◽  
Mihai Dumitru ◽  
Ciprian Paraschiv
Keyword(s):  
Shape Memory Alloys ◽  
Shape Memory ◽  
Spinal Cord Injuries ◽  
Good Alternative ◽  
Careful Consideration ◽  
Damping Capacity ◽  
Loss Of Function ◽  
User Friendliness ◽  
Wide Range ◽  
Constructive Models

Entire or partial loss of function in the shoulder, elbow or wrist represent an increasingly common ailment connected to a wide range of injuries or other conditions including sports, occupational, spinal cord injuries or strokes. A general treatment of these problems relies on physiotherapy procedures. An increasing number of metallic materials are continuously being developed to expect the requirements for different engineering applications including biomedical field. Few constructive models that can involve intelligent materials are analyzed to establish the advantages in usage of shape memory elements mechanical implementation. The shape memory effect, superelasticity and damping capacity are unique characteristics at metallic alloys which demand careful consideration in both design and manufacturing processes. The actual rehabilitation systems can be improved using smart elements in motorized equipments like robotic systems. Shape memory alloys, especially NiTi (nitinol), represent a very good alternative for actuation in equipments with moving dispositive based on very good actuation properties, low mass, small size, safety and user friendliness. In this article the actuation and the force characteristics were analyzed to investigate a relationship between the bending angle and the actuation real value.

Pancreatic Cysts: Pathologic Classification, Differential Diagnosis, and Clinical Implications

2009 ◽  
Vol 133 (3) ◽  
pp. 423-438 ◽  
Author(s):  
Olca Basturk ◽  
Ipek Coban ◽  
N. Volkan Adsay
Keyword(s):  
Differential Diagnosis ◽  
Malignant Potential ◽  
Common Finding ◽  
Pancreatic Cysts ◽  
Pancreatic Ducts ◽  
Low Grade ◽  
Cystic Lesions ◽  
Dismal Prognosis ◽  
Cystic Tumors ◽  
Pathologic Classification

Abstract Context.—Cystic lesions of the pancreas are being recognized with increasing frequency and have become a more common finding in clinical practice because of the widespread use of advanced imaging modalities and the sharp drop in the mortality rate of pancreatic surgery. Consequently, in the past 2 decades, the nature of many cystic tumors in this organ has been better characterized, and significant developments have taken place in the classification and in our understanding of pancreatic cystic lesions. Objective.—To provide an overview of the current concepts in classification, differential diagnosis, and clinical/biologic behavior of pancreatic cystic tumors. Data Sources.—The authors' personal experience, based on institutional and consultation materials, combined with an analysis of the literature. Conclusions.—In contrast to solid tumors, most of which are invasive ductal adenocarcinomas with dismal prognosis, cystic lesions of the pancreas are often either benign or low-grade indolent neoplasia. However, those that are mucinous, namely, intraductal papillary mucinous neoplasms and mucinous cystic neoplasms, constitute an important category because they have well-established malignant potential, representing an adenoma-carcinoma sequence. Those that are nonmucinous such as serous tumors, congenital cysts, lymphoepithelial cysts, and squamoid cyst of pancreatic ducts have no malignant potential. Only rare nonmucinous cystic tumors that occur as a result of degenerative/necrotic changes in otherwise solid neoplasia, such as cystic ductal adenocarcinomas, cystic pancreatic endocrine neoplasia, and solid-pseudopapillary neoplasm, are also malignant and have variable degrees of aggressiveness.

Clinical case of recurrent vomiting in a child: diagnostic search from functional gastrointestinal disorders to piloid astrocytoma

2021 ◽  
Vol 19 (1) ◽  
pp. 78-81
Author(s):  
E. N. Voronina ◽  
◽  
D. V. Pechkurov ◽  
A. A. Tyazheva ◽  
E. V. Kozarez ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Nutritional Status ◽  
Clinical Case ◽  
Anxiety Symptom ◽  
Functional Gastrointestinal Disorders ◽  
Integrated Approach ◽  
Gastrointestinal Disorders ◽  
Wide Range ◽  
High Prevalence ◽  
Recurrent Vomiting

The urgency of the problem of recurrent vomiting in children is due not only to the high prevalence of this syndrome, but also to a wide range of reasons for its development. The article presents a clinical case of observation of a child with recurrent vomiting syndrome. It shows the dynamics of the disease, the importance of identifying such «anxiety symptom» as the nutritional status violation. In this case, the cause of vomiting of central genesis was not immediately taken into account, although differential diagnosis presupposes an integrated approach, and doctors' oncological alertness should be constantly preserved even in pediatrics.

Sign in / Sign up

Export Citation Format

Share Document