FACTORS AFFECTING DELAY IN DIAGNOSIS OF COLORECTAL CANCER: A CROSS-SECTIONAL STUDY; FROM TERTIARY CARE HOSPITAL OF KARACHI PAKISTAN

Background: CRC incidence is increasing in our region. There is no specific CRC control program or national cancer registry in Pakistan. Previously no data has been published on presentation and diagnosis delay of CRC in our region. This study is conducted to determine the factor affecting delay in presentation and diagnosis and to provide baseline information to launch a CRC control program. Primary objective is to determine factor causing delay in diagnosis of CRC. Secondary objective is to evaluate relationship between tumor site and stage of CRC with presenting symptoms and symptom duration. Methods: This project is a prospective cross-sectional study on 113 biopsy-proven CRC patients admitted to the surgical ward of civil hospital Karachi. Results: A total number of participants was 113. Presentation delay was observed in 83.2% of patients. The main reasons for a reported delay in the presentation were lack of patients’ knowledge that these symptoms may be cancer (60.4%), the wrong diagnosis by the primary physician (34.6%), or the patient didn’t want to visit the doctor (0.04%). Most tumors (95%) originated from the sigmoid and rectum. 38.9% and 44.2% of the patients diagnosed at Stage 4 and 3 respectively. Conclusions: This study revealed that CRC patients in Pakistan are facing delays in presentation and diagnosis. This is the reason behind diagnosis at the advanced stage with a poor prognosis. Based on this study findings CRC control program should be introduced to detect CRC at an early stage. Keywords: Colorectal cancer, Colon, Rectum, Cancer, Presentation delay, Diagnosis delay.

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Factors affecting delay in diagnosis of colorectal cancer; a cross sectional study; from tertiary care hospital of Karachi Pakistan

International Journal of Clinical Practice ◽

10.1111/ijcp.14529 ◽

2021 ◽

Author(s):

Rubab Nafees Ahmed ◽

Lajpat Rai ◽

Khursheed Ahmed Samo ◽

Summaya Saeed ◽

Ammara Salam ◽

...

Keyword(s):

Colorectal Cancer ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Cross Sectional Study ◽

Care Hospital ◽

Sectional Study ◽

Cross Sectional ◽

Factors Affecting ◽

Delay In Diagnosis

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A study of clinical profile of patients with Dengue fever at a tertiary care hospital

International Journal of Advances in Medicine ◽

10.18203/2349-3933.ijam20180085 ◽

2018 ◽

Vol 5 (1) ◽

pp. 202 ◽

Cited By ~ 1

Author(s):

Sreenivasulu T. ◽

Jahnavi K.

Keyword(s):

Dengue Fever ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Cross Sectional Study ◽

Clinical Profile ◽

Care Hospital ◽

Age Group ◽

Sectional Study ◽

Cross Sectional ◽

Presenting Symptoms

Background: Dengue is the most common fever. Among all flavi-viruses, it is the most common. It can cause around 50-100 million infections. Every year 2-5 lakh cases of Dengue hemorrhagic fever occur. The objective of the research was to study clinical profile of patients with Dengue fever at a tertiary care hospital.Methods: Present study was cross sectional study. The patients were interviewed and examined at one point of time and later they were never followed which is similar to the cross-sectional study design. Present study was carried out in the hospital. This was done in the department of General Medicine of a tertiary care hospital. Present study was carried out over a period of one year.Results: In the present study, there were 78 males and 22 females. The sex ratio was 3.5:1. Maximum number of males (29.5%) was in the age group of 15-25. Among females, the maximum (40.9%) were in the age group of 26-35 years and 46-55 years (9%). The most common presenting symptom was fever in all cases followed by headache in 90%. Among bleeding manifestations, epistaxis, gum bleeding and hematuria (15%) were the common symptoms. Most patients presented with generalized lymphadenopathy in 52%. 56 patients showed only hepatomegaly and 46 splenomegaly, and 30 patients showed hepato splenomegaly. 99 showed leucopenia and 10 were anemic and 25 showed platelet count less than 1,50,000cells/cumm.Conclusions: Males were commonly affected. Younger age group of 15-25 was most commonly affected and fever and headache were the most common presenting symptoms. These findings help physicians in early diagnosis of dengue by suspecting these features as of dengue and can prevent morbidity and mortality associated with dengue.

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Assessment of COVID-19 Management at Saidu Group of Teaching Hospital Swat: Analytical Cross-Sectional Study

Pakistan Journal of Public Health ◽

10.32413/pjph.v11i2.726 ◽

2021 ◽

Vol 11 (2) ◽

pp. 102-106

Author(s):

Akhtar Ali Khan ◽

Anwar Ali ◽

Hussan Zeb ◽

Bakht Rahman ◽

Ijaz Arif ◽

...

Keyword(s):

Teaching Hospital ◽

Tertiary Care ◽

Treatment Protocol ◽

Target Population ◽

Cross Sectional Study ◽

Care Hospital ◽

Sectional Study ◽

Cross Sectional ◽

Presenting Symptoms ◽

Study Results

Background: This research aimed to assess the current care management processes for COVID-19 and determine patient outcomes. Methods: An analytical cross-sectional study was conducted at Saidu group of teaching hospital, a tertiary care hospital with more than a thousand-bed capacity. The target population was all patients admitted to the corona isolation ward and the hospital's critical unit. All the patients admitted through the emergency and inpatient department with Positive PCR, and respiratory symptoms were included in the study. Results: In total, data of 151 patients were collected. Of these, 90 (59.6%) were male and 61 (40.4%) were female with a mean age of 59.17±13.79. The most common presenting symptoms were difficulty in breathing (n=147, 97.4%) and dry cough (n=104, 68.9%), followed by aches and pain (n=71, 47%) and fever (n=60, 39.7%). Most of the patients had an underlying health condition (n=96, 63.6%). The most common underlying conditions were hypertension (n=65, 43%) and diabetes (n=56, 37.1%). The mean time for the hospital stay was 11.68±15.31. About 64% of the patients recovered with the treatment and care protocols (n=97, 64.2%), while the remaining (n=54, 35.8%) died. Conclusion: This study provides an overview of the clinical presentation and treatment protocol for COVID-19. Most of the patients received supportive treatment comprising of antivirals, steroids, and oxygen therapy. However, the mortality rate was low compared to other hospitals across the country.

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Presenting symptoms and diagnosis of vulvar lichen sclerosus in premenopausal women: a cross-sectional study

10.22541/au.162822171.13489994/v1 ◽

2021 ◽

Author(s):

Jill Krapf ◽

Alyssa Smith ◽

Sarah Cigna ◽

Andrew Goldstein

Keyword(s):

Premenopausal Women ◽

Lichen Sclerosus ◽

Cross Sectional Study ◽

Medical Attention ◽

Sectional Study ◽

Cross Sectional ◽

Web Based ◽

Delay In Diagnosis ◽

Presenting Symptoms ◽

The Individual

Objective: Characterize the presentation of vulvar lichen scleorsus (LS) among premenopausal women. Design: Cross-sectional study. Setting: An international web-based survey distributed on social media support groups and in two urban gynecology offices specializing in LS. Population: A total of 503 premenopausal women with biopsy-confirmed vulvar LS between the ages of 18-50. Methods: Participants completed an anonymous 28-question web-based survey between January to March 2021. Main Outcome Measures: Symptoms, timing and accuracy of diagnosis, and presence of concomitant autoimmune conditions. Results: Symptoms reported to be most present and affect the individual were dyspareunia (68%; 44%) and tearing with intercourse or vaginal insertion (63%; 39%). Symptoms that most frequently prompted patients to seek medical attention were dyspareunia (35%), pruritus (31%), and tearing with intercourse or vaginal insertion (26%). Most common skin changes included hypopigmentation (81%), vulvar fissures (72%) and labial resorption (60%), with fissures affecting the individual the most (48%). There was a 4-year delay in diagnosis with an average age of symptom onset of 27 years and average age of diagnosis of 32 years. Sixty-six percent of respondents initially received an alternative diagnosis, most commonly vulvovaginal yeast infection (49%). There is an increased incidence of hypothyroidism, vitiligo, pernicious anemia, and celiac disease. Conclusion: Premenopausal women with vulvar LS more commonly present with dyspareunia and tearing with intercourse, less often than vulvar pruritis. This condition should be considered and evaluated in women of all ages presenting with vulvar symptoms and sexual pain. Funding: None Keywords: lichen sclerosus; vulvar dermatoses; vulvar pruritis; dyspareunia

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