scholarly journals Presenting symptoms and diagnosis of vulvar lichen sclerosus in premenopausal women: a cross-sectional study

2021 ◽  
Author(s):  
Jill Krapf ◽  
Alyssa Smith ◽  
Sarah Cigna ◽  
Andrew Goldstein
Keyword(s):  
Premenopausal Women ◽  
Lichen Sclerosus ◽  
Cross Sectional Study ◽  
Medical Attention ◽  
Sectional Study ◽  
Cross Sectional ◽  
Web Based ◽  
Delay In Diagnosis ◽  
Presenting Symptoms ◽  
The Individual

Objective: Characterize the presentation of vulvar lichen scleorsus (LS) among premenopausal women. Design: Cross-sectional study. Setting: An international web-based survey distributed on social media support groups and in two urban gynecology offices specializing in LS. Population: A total of 503 premenopausal women with biopsy-confirmed vulvar LS between the ages of 18-50. Methods: Participants completed an anonymous 28-question web-based survey between January to March 2021. Main Outcome Measures: Symptoms, timing and accuracy of diagnosis, and presence of concomitant autoimmune conditions. Results: Symptoms reported to be most present and affect the individual were dyspareunia (68%; 44%) and tearing with intercourse or vaginal insertion (63%; 39%). Symptoms that most frequently prompted patients to seek medical attention were dyspareunia (35%), pruritus (31%), and tearing with intercourse or vaginal insertion (26%). Most common skin changes included hypopigmentation (81%), vulvar fissures (72%) and labial resorption (60%), with fissures affecting the individual the most (48%). There was a 4-year delay in diagnosis with an average age of symptom onset of 27 years and average age of diagnosis of 32 years. Sixty-six percent of respondents initially received an alternative diagnosis, most commonly vulvovaginal yeast infection (49%). There is an increased incidence of hypothyroidism, vitiligo, pernicious anemia, and celiac disease. Conclusion: Premenopausal women with vulvar LS more commonly present with dyspareunia and tearing with intercourse, less often than vulvar pruritis. This condition should be considered and evaluated in women of all ages presenting with vulvar symptoms and sexual pain. Funding: None Keywords: lichen sclerosus; vulvar dermatoses; vulvar pruritis; dyspareunia

scholarly journals FACTORS AFFECTING DELAY IN DIAGNOSIS OF COLORECTAL CANCER: A CROSS-SECTIONAL STUDY; FROM TERTIARY CARE HOSPITAL OF KARACHI PAKISTAN

2021 ◽  
Author(s):  
Rubab Nafees Ahmed ◽  
Lajpat Rai ◽  
Khursheed Ahmed Samo ◽  
Summaya Saeed ◽  
Ammara Salam ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Control Program ◽  
Cross Sectional Study ◽  
Diagnosis Delay ◽  
Care Hospital ◽  
Sectional Study ◽  
Cross Sectional ◽  
Delay In Diagnosis ◽  
Presenting Symptoms ◽  
Keywords Colorectal Cancer

Background: CRC incidence is increasing in our region. There is no specific CRC control program or national cancer registry in Pakistan. Previously no data has been published on presentation and diagnosis delay of CRC in our region. This study is conducted to determine the factor affecting delay in presentation and diagnosis and to provide baseline information to launch a CRC control program. Primary objective is to determine factor causing delay in diagnosis of CRC. Secondary objective is to evaluate relationship between tumor site and stage of CRC with presenting symptoms and symptom duration. Methods: This project is a prospective cross-sectional study on 113 biopsy-proven CRC patients admitted to the surgical ward of civil hospital Karachi. Results: A total number of participants was 113. Presentation delay was observed in 83.2% of patients. The main reasons for a reported delay in the presentation were lack of patients’ knowledge that these symptoms may be cancer (60.4%), the wrong diagnosis by the primary physician (34.6%), or the patient didn’t want to visit the doctor (0.04%). Most tumors (95%) originated from the sigmoid and rectum. 38.9% and 44.2% of the patients diagnosed at Stage 4 and 3 respectively. Conclusions: This study revealed that CRC patients in Pakistan are facing delays in presentation and diagnosis. This is the reason behind diagnosis at the advanced stage with a poor prognosis. Based on this study findings CRC control program should be introduced to detect CRC at an early stage. Keywords: Colorectal cancer, Colon, Rectum, Cancer, Presentation delay, Diagnosis delay.

Awareness of the preventive measures against Covid -19 spread among small shop owners

2020 ◽  
Vol 11 (SPL1) ◽  
pp. 1144-1150
Author(s):  
Muralidharan V A ◽  
Gheena S
Keyword(s):  
Infectious Disease ◽  
Data Analysis ◽  
Preventive Measures ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Positive Perception ◽  
Cross Sectional ◽  
Web Based ◽  
Small Shop ◽  
Structured Questionnaire

Covid -19 is an infectious disease caused by the newly discovered strain of coronavirus. As there is no vaccine discovered, the only way to prevent the spread is through following the practice of social isolation. But prolonged isolation may also lead to psychological stress and problems. The objective of the survey was to assess the knowledge and awareness of preventive measures against Covid 19 amongst small shop owners. A web-based cross-sectional study was conducted amongst the small shop owners.  A structured questionnaire comprising 15-17 questions had been put forth to assess the Covid 19 related knowledge and perception. The shopkeepers were contacted telephonically and responses recorded. The data analysis was performed using IBM SPSS statistics. Although the majority of the population had a positive perception about the preventive measures against the Covid spread, 36% of the shopkeepers were not aware of the preventive measures against the Covid spread. This study found optimal knowledge and perception of the preventive measures against Covid spread among the shopkeepers but misinformation and misunderstanding still prevailing. The shopkeepers are crucial in the prevention of the spread of Covid 19 and educating them might aid us in the fight against Covid- 19. 

scholarly journals Acceptability of COVID-19 vaccination in Saudi Arabia: A cross-sectional study using a web-based survey

2021 ◽  
pp. 1-10
Author(s):  
Saeed Mastour Alshahrani ◽  
Salem Dehom ◽  
Diaa Almutairi ◽  
Badr Saud Alnasser ◽  
Bandar Alsaif ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Web Based

scholarly journals Low health literacy is associated with higher risk of type 2 diabetes: a cross-sectional study in Germany

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Daniel Tajdar ◽  
Dagmar Lühmann ◽  
Regina Fertmann ◽  
Tim Steinberg ◽  
Hendrik van den Bussche ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Health Literacy ◽  
Statistical Models ◽  
Cross Sectional Study ◽  
Diabetes Risk ◽  
Sectional Study ◽  
Cross Sectional ◽  
Low Health Literacy ◽  
The Individual

Abstract Background Low health literacy is believed to be associated with behaviours that increase the risk of type 2 diabetes. But there is limited knowledge on the relation between health literacy (HL) and diabetes risk, and whether improving HL could be a potential prevention strategy. Therefore, the main purpose of this study was to examine the link between HL and diabetes risk among non-diabetic adults. Methods We used data from the Hamburg Diabetes Prevention Survey, a population-based cross-sectional study in Germany. One thousand, two hundred and fifty-five non-diabetic subjects aged 18–60 years were eligible. The German Diabetes Risk Score (GDRS, ranging 0 to 123 points) was used to determine the individual risk of type 2 diabetes. The short version of the European Health Literacy Questionnaire (HLS-EU-Q16, ranging 0 to 16 points) was applied to assess the individual self-reported HL. Subjects were asked to self-estimate their diabetes risk, which was then compared with the calculated GDRS. Descriptive statistics were calculated to investigate group differences in the GDRS and self-estimated diabetes risk. Linear as well as logistic regression models were performed to analyse potential influencing variables of the GDRS as well as incorrect self-estimated diabetes risk. In three nested statistical models for each outcome, these analyses were adjusted for age, gender, educational level and the presence of chronic conditions. Results According to the criteria of the GDRS, 996 (79.4%) subjects showed “low risk”, 176 (14.0%) “still low risk”, 53 (4.2%) “elevated risk”, and 30 (2.4%) “high to very high risk” to develop type 2 diabetes within the next 5 years. In the statistical models including all control variables, subjects with “inadequate HL” scored 2.38 points higher on the GDRS (95% CI 0.378 to 4.336; P = 0.020) and had a 2.04 greater chance to estimate their diabetes risk incorrectly (OR 2.04; 95% CI 1.33 to 3.14; P = 0.001) compared to those with “sufficient HL”. Conclusion The risk of type 2 diabetes is increased in people with inadequate self-reported HL. People with high diabetes risk and inadequate HL might be provided with educational programs to improve diabetes knowledge and reduce behavioural risk factors.

scholarly journals New Images for Old Symbols: Meanings That Children Give to a Traditional Game

2021 ◽  
Vol 12 ◽  
Author(s):  
Alfonso García-Monge ◽  
Henar Rodríguez-Navarro ◽  
Daniel Bores-García
Keyword(s):  
Cross Sectional Study ◽  
Sectional Study ◽  
Cultural Meanings ◽  
Cross Sectional ◽  
The Individual ◽  
Age Range ◽  
Traditional Game

Traditional games are considered agents of enculturation. This article explores the procedure to access the cultural meanings transmitted in a traditional game. The goal is to understand what children aged 6–11 make of the game called ‘the chained bear’ and to compare the meanings retrieved with those of different traditional versions of the game. For such a purpose, through an exploratory cross-sectional study, cartoons depicting people playing the game were exhibited and viewers (n = 359; age range: 6–11; Mean age = 8.79; SD = 1.81) were asked to interpret them as a drama play, as well as contributing a title, a plot and saying how they would name the characters. The results show that, beyond the individual images that each child created in their mind, most of them coincided in stories about harassment and defense and theft and protection. These plots match those of the ludic tradition, showing that the actions evoke different pictures to each individual, but share common cultural meanings in turn. The study shows a procedure to access the meanings that traditional games transmit and confirms that games contain pieces of culture, which makes them agents of enculturation.

scholarly journals A study of the knowledge and attitude of physicians in the first aid management of epistaxis in Aseer region, Saudi Arabia

2019 ◽  
Vol 5 (6) ◽  
pp. 1457
Author(s):  
Abdullah Musleh ◽  
Sarah Ali AlShehri ◽  
Anas Mohammed AlShehri ◽  
Sultan Khalid Kadasah ◽  
Mohammed Sharaf Alshahrani ◽  
...  
Keyword(s):  
Demographic Data ◽  
Total Sample ◽  
First Aid ◽  
Cross Sectional Study ◽  
Nasolacrimal Duct ◽  
Medical Attention ◽  
Sectional Study ◽  
Cross Sectional ◽  
The Common ◽  
Knowledge And Attitude

<p class="abstract"><strong>Background:</strong> Epistaxis is the common occurrence of bleeding from the nose. It is usually noticed when blood drains out through the nostrils. There are two types: anterior (the most common), and posterior (less common, more likely to require medical attention). Sometimes in more severe cases, the blood can come up the nasolacrimal duct and out from the eye<span lang="EN-IN">. </span></p><p class="abstract"><strong>Methods:</strong> A cross-sectional study was conducted in main five hospitals in Aseer region targeting residents dealing with emergency room (ER) cases during the period from 1st July to 31st July, 2018. Data were collected using a pre-structured written questionnaire by the researchers. The questionnaire composed of three parts. First part was for residents’ demographic data. Second part considered epistaxis cases rate and treatment. Third part covered 10 questions for knowledge regarding epistaxis<span lang="EN-IN">.  </span></p><p class="abstract"><strong>Results:</strong> A total sample of 165 residents was involved with ages ranged from 27 years to 32 years old and 65.5% of the sampled residents were males. Exact of 47.3% of the residents were ER residents and 24.2% were general practitioners (GPs)<span lang="EN-IN">. </span></p><p class="abstract"><strong><span lang="EN-IN">Conclusions:</span></strong><span lang="EN-IN"> Nearly one out of each four residents had good awareness level regarding epistaxis especially GPs and ER residents. Position of patients with epistaxis and sites of epistaxis were the only items well known by residents. </span></p>

scholarly journals Genetic homozygosity as a marker of smoking dependency

Genetika ◽  
2020 ◽  
Vol 52 (3) ◽  
pp. 1009-1019
Author(s):  
Slavko Brankovic ◽  
Dejan Nikolic ◽  
Dragoslav Marinkovic ◽  
Suzana Cvjeticanin
Keyword(s):  
Cross Sectional Study ◽  
Male Gender ◽  
Sectional Study ◽  
Cross Sectional ◽  
Male And Female ◽  
Mean Values ◽  
Individual Variations ◽  
Significant Difference ◽  
The Mean ◽  
The Individual

The aim of our study was to evaluate the morphogenetic variability as a marker of smoking dependency in adult smokers versus controls and to investigate the presence and the degree of morphogenetic variability difference between male and female smokers versus same gender controls. The cross-sectional study evaluated 241 smokers and 185 nonsmoker individuals as controls. We analyzed 17 homozygous recessive characteristics (HRC). There was a significant difference in the individual variations of 17 HRCs between the controls and smokers (??2=61.400, p<0.001; for females ??2=79.440, p<0.001; for males ??2=84.972, p<0.001). The mean values of HRCs significantly differed between smokers and controls (MV?SEM(Controls) -4.79?0.13, MV?SEM(Smokers) -5.70?0.12; p<0.001). For males, presence of 6/17 (35.29% genetic homozygosity) HRCs (OR=6.12) was to the certain degree predictor for smoking dependency. Higher degree of genetic homozygosity, changed variability and male gender, might be some among potential numerous factors that could have impact on smoking development and dependence.

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