scholarly journals Routes and types of microbial infection in the pathology of pancreatic adenocarcinoma

2021 ◽  
pp. 71-71
Author(s):  
Dragan Nikolic ◽  
Stojan Latincic ◽  
Milos Stojanovic ◽  
Nikica Grubor ◽  
Lazar Ranin ◽  
...  

Introduction/Objective. Pancreatic cancer may be accompanied by infections caused by various microorganisms. It is uncertain wheatear pancreatic infection precedes development of cancer or vice versa. The aim of this study is to analyze routes of infections from duodenum through pancreatic duct to determine what types of microorganisms can get through this duct into pancreas and nearby tissue. Methods. In patients subjected to cephalic duodenopancreatectomy sec. Whipple due to adenocarcinoma of papilla Vateri, duodenum or head of the pancreas, swabs from duodenal mucosa, pancreatic duct and pancreatic tissue at the line of the resection, were taken. Microscopic slides were prepared directly from patients? specimens and also from colonies on culture plates and both were Gram stained. Results. Candida was present in all three types of swabs (duodenum, pancreatic duct and tissue), while bacteria, depending of the species (Pseudomonas aeruginosa. ? hemolytic Streptococcus, Coagulase Negative Staphylococcus, Enterococcus spp, Serratia spp), were present in pancreatic duct or tissue, but not in duodenum. Conclusion. There is connection between presence of microorganisms and pathology of the pancreatic adenocarcinoma. Results show that Candida infection originates from duodenum, while bacterial infections originate directly from blood or tissue injuries.

2019 ◽  
Vol 0 (3) ◽  
pp. 13-18
Author(s):  
M. S. Zagriichuk ◽  
I. I. Bulik ◽  
A. I. Hutsuliak ◽  
K. P. Tumasova ◽  
Y. V. Nezhentseva ◽  
...  

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Marta Cáceres ◽  
Rita Quesada ◽  
Mar Iglesias ◽  
Francisco X. Real ◽  
Maria Villamonte ◽  
...  

An amendment to this paper has been published and can be accessed via a link at the top of the paper.


1988 ◽  
Vol 118 (2) ◽  
pp. 227-232 ◽  
Author(s):  
L. G. Guijarro ◽  
E. Arilla

ABSTRACT Atrophy of the exocrine pancreas was induced in rabbits by pancreatic duct ligation. Somatostatin concentration and binding in cytosol from rabbit duodenal mucosa were studied after 6 and 14 weeks of pancreatic duct ligation. Somatostatin-like immunoreactivity was significantly increased in the duodenal mucosa in both periods. Scatchard analysis showed a parallel increase in the number of binding sites rather than a change in their affinity. The physiological significance of these findings remains to be clarified. J. Endocr. (1988) 118, 227–232


2019 ◽  
Vol 6 (8) ◽  
pp. e00147
Author(s):  
Takeru Yamaguchi ◽  
Yoshihiko Kadowaki ◽  
Takeshi Okino ◽  
Eriko Uehara ◽  
Mika Ohmori ◽  
...  

HPB ◽  
2020 ◽  
Vol 22 ◽  
pp. S318
Author(s):  
R. Rhaiem ◽  
O. Delchet ◽  
A. Tashkandi ◽  
S. Deguelte ◽  
M. Brasseur ◽  
...  

1990 ◽  
Vol 4 (9) ◽  
pp. 568-571 ◽  
Author(s):  
Claude Liguory ◽  
Jean Francois Lefebvre ◽  
Gary C Vitale

Endoscopic drainage of pancreatic pseudocysts was attempted in 17 patients over an eight year period. There were nine cysts located in the head of the pancreas, six in the body and two in the tail. Endoscopic retrograde cholangiopancreatography was performed in all cases and the pancreatic duct satisfactorily opacified in 16 of the 17 patients. This study identified a communication with the pancreatic duct in seven cases. There were two cases in which multiple cysts were present; in each, one cyst was drained endoscopically and the others surgically. Endoscopic drainage of the cyst was immediately possible in 16 of 17 cases (94%). Late follow-up (mean 26 months) documented cyst disappearance in 11 cases (69%). None of the five patients with persistent cysts has required secondary surgical intervention, and the cysts are asymptomatic and stable or decreasing in size by serial scanning. There was one case (6%) in which a pseudocyst recurred following initial resolution. There were two complications (12%) requiring surgical intervention: gastrointestinal perforation with peritonitis in one patient and hemorrhage at the cyst margin from an arterial bleeder in another. There were no deaths at 30 days, but in one case a recurrent acute necrotizing pancrearitis occurred 36 days following endoscopic drainage and the patient died. This death was felt to be unrelated to the endoscopic procedure. In conclusion, internal drainage of pancreatic pseudocysts by endoscopic means can be proposed as an alternative to surgical drainage when the cyst can be identified as bulging into the stomach or duodenum. Immediate drainage is usually effective with a minimal long term recurrence rate.


2020 ◽  
pp. postgradmedj-2020-139090
Author(s):  
Rajanbir Kaur ◽  
Rajinder Kaur

Urinary tract infection (UTI) is a common microbial infection found in all ages and sexes which involves inflammation of the urinary tract. These infections can range from simple bladder inflammation, that is, cystitis, to severe cases of uroseptic shock. UTI ranks as the number 1 infection that leads to a prescription of antibiotics after a doctor’s visit. These infections are sometimes distressing and even life threatening, and both males (12%) and females (40%) have at least one symptomatic UTI throughout their lives. Diagnostic failures in case of bacterial infections are the main contributing factor in improper use of antibiotics, delay in treatment and low survival rate in septic conditions. So, early diagnosis and appropriate therapy with antibiotics are the most significant requirements for preventing complicated UTI conditions such as urosepsis. This review article summarises the symptoms of the UTIs and the associated risk factors to it. The various conventional and recent diagnostic methods were also discussed in this review, along with treatment therapies with or without antibiotics.


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