scholarly journals Significance of Neospora caninum in cattle farming

2006 ◽  
Vol 60 (3-4) ◽  
pp. 223-231
Author(s):  
Tamara Ilic ◽  
Sanda Dimitrijevic
Keyword(s):  
Neospora Caninum ◽  
Protozoan Parasite ◽  
The United States ◽  
Neonatal Deaths ◽  
Obligate Intracellular ◽  
The World ◽  
Three Stages ◽  
Almost All ◽  
Cycle Covers ◽  
Intracellular Protozoan Parasite

Neospora caninum is an obligate intracellular protozoan parasite which primarily causes diseases in dogs and cattle all over the world. It was first described in Norway in the mid-eighties in dogs, after which, until the present time, clinical neosporosis was proven in sheep, goats, deer, rhinoceroses, horses, and experimental rodents. Antibodies against N. caninum have been found also in the serum of water buffalo, red and gray foxes, coyotes, camels, and felines. Due to the similarity of this Coccidia with Toxoplasma gondi, the neosporosis was for a series of years incorrectly diagnozed as toxoplasmosis. Domestic canines, dogs, are the only real host for N. caninum. Its life cycle covers three stages of development: tachyzoites, tissue cysts and oocysts. Carnivores are infected by ingesting parts of infected tissue which contain tissue cysts with bradyzoites. The dominant pathway of transmission of this cause in cattle is transplacentary infection, but cattle can also be infected by ingestion of feed or water contaminated by sporulated oo-cysts of N. caninum. Bitches can be subclinical carriers of the parasite, when they pass on the cause transplacentarily, which results in more than one litter being born with the infection. Neosporosis today appears as the main cause of abortions and neonatal deaths in dairy cows and fattening cattle in almost all parts of the world, but with the highest incidence in the United States (US), New Zealand, The Netherlands, and Germany. The treatment of this disease has not been fully determined, but medicines used for the treatment of toxoplasmosis have yielded certain good results. There is no verified vaccine that would prevent undesired abortions in cattle. .

scholarly journals ToxoplasmaRhoptries: Unique Secretory Organelles and Source of Promising Vaccine Proteins for Immunoprevention of Toxoplasmosis

2008 ◽  
Vol 2008 ◽  
pp. 1-7 ◽  
Author(s):  
Henryka Dlugonska
Keyword(s):  
Neospora Caninum ◽  
Parasitophorous Vacuole ◽  
Protozoan Parasite ◽  
Current Data ◽  
Intracellular Killing ◽  
Apicomplexan Parasites ◽  
Obligate Intracellular ◽  
Animal Pathogens ◽  
Intracellular Protozoan Parasite

Toxoplasma gondiiis an obligate intracellular protozoan parasite classified in the phylum Apicomplexa, which includes numerous notable human and animal pathogens (Plasmodiumspecies,Cryptosporidiumspecies,Neospora caninum, etc.). The invasive stages of apicomplexans are characterized by the presence of an apical complex composed of specialized cytoskeletal and secretory organelles, including rhoptries. Rhoptries, unique apical secretory organelles shared exclusively by all apicomplexan parasites, are known to be involved in an active parasite's penetration into the host cell associated with the biogenesis of specific intracellular compartment, parasitophorous vacuole in which the parasite multiplies intensively, avoiding intracellular killing. Due to the key biological role of rhoptries, rhoptry proteins have recently become vaccine candidates for the prevention of several parasitoses, toxoplasmosis among them. The article presents current data onT. gondiirhoptries biology and new approaches to the development of effective vaccines against toxoplasmosis using rhoptry antigens.

scholarly journals The Effect of Vaccination Rates on the Infection of COVID-19 under the Vaccination Rate below the Herd Immunity Threshold

2021 ◽  
Vol 18 (14) ◽  
pp. 7491
Author(s):  
Yi-Tui Chen
Keyword(s):  
Infection Rate ◽  
Herd Immunity ◽  
The United States ◽  
Vaccination Rate ◽  
Infection Rates ◽  
Vaccination Rates ◽  
The United Kingdom ◽  
The World ◽  
Almost All ◽  
The Impact

Although vaccination is carried out worldwide, the vaccination rate varies greatly. As of 24 May 2021, in some countries, the proportion of the population fully vaccinated against COVID-19 has exceeded 50%, but in many countries, this proportion is still very low, less than 1%. This article aims to explore the impact of vaccination on the spread of the COVID-19 pandemic. As the herd immunity of almost all countries in the world has not been reached, several countries were selected as sample cases by employing the following criteria: more than 60 vaccine doses per 100 people and a population of more than one million people. In the end, a total of eight countries/regions were selected, including Israel, the UAE, Chile, the United Kingdom, the United States, Hungary, and Qatar. The results find that vaccination has a major impact on reducing infection rates in all countries. However, the infection rate after vaccination showed two trends. One is an inverted U-shaped trend, and the other is an L-shaped trend. For those countries with an inverted U-shaped trend, the infection rate begins to decline when the vaccination rate reaches 1.46–50.91 doses per 100 people.

Low Birth Weight, Vital Records, and Infant Mortality

PEDIATRICS ◽  
1986 ◽  
Vol 78 (6) ◽  
pp. 1143-1145
Author(s):  
MYRON E. WEGMAN
Keyword(s):  
Birth Weight ◽  
Infant Mortality ◽  
Low Birth Weight ◽  
Very Low Birth Weight ◽  
The United States ◽  
Low Birth Weight Infants ◽  
Neonatal Deaths ◽  
Live Births ◽  
Order Of Magnitude ◽  
Almost All

About one tenth of all infant deaths occur in babies weighing less than 500 g at birth, almost all of whom die very shortly thereafter. In 1983, when the United States reported 3,638,933 live births, 4,368 of them were less than 500 g; that year there were 26,507 neonatal deaths. This means that slightly more than 0.1% of all live births contributed to 17% of neonatal mortality. Given this order of magnitude, any change in the numbers relating to these tiny babies can have a disproportionate influence on reported infant mortality and on interstate comparisons. Two questions promptly arise. How accurate and meaningful are the data regarding babies born weighing less than 500 g? What can be done to decrease the deaths in this category? Wilson et al1 call attention to how the number of very low birth weight infants reported by a state may be affected by the state's definition of a live birth.

Unique report of two Sarcocystis species from Egyptian domestic chicken (Gallus gallus) – new host and locality

2021 ◽  
Vol 24 (1) ◽  
pp. 152-158
Author(s):  
E. M. Galila ◽  
E. K. A. Bazh ◽  
N. Elhawary ◽  
H. A. Abdellatif ◽  
A.-R. A. Abou-Rawash
Keyword(s):  
Nile Delta ◽  
Protozoan Parasite ◽  
Intestinal Wall ◽  
Sarcocystis Species ◽  
Middle Region ◽  
New Host ◽  
Sarcocystis Spp ◽  
Hexagonal Shape ◽  
The World ◽  
Intracellular Protozoan Parasite

Sarcocystis is an intracellular protozoan parasite in the phylum Apicomplexa. It is widely distributed all over the world. There are scarce reports about chicken Sarcocystis. From February 2016 to January 2018, a total number of 630 chicken carcasses, intestines and viscera were collected from different chicken markets in Menoufia and Gharbia Governorates, Middle region of the Nile Delta, Egypt and carefully inspected. Macroscopic and microscopic cysts of Sarcocystis spp. were found in the intestinal wall and mesentery of 5 birds. Histopathological sections revealed the presence of two shapes of the macroscopic cysts (oval and kidney shape). Their wall was striated and characterised by the presence of radial septa. It had compartments mostly of hexagonal shape, containing both bradyzoites and metrocytes in the periphery. The bradyzoites were banana-shaped and measured 20–30 × 8–10 μm with centrally or posteriorly located nuclei. Microscopic cysts of Sarcocystis spp. were detected in-between muscle bundles, with variable shapes (spindle and oval).

Part IV: Resettlement: Voluntary Agencies and the Resettlement of Refugees

1981 ◽  
Vol 15 (1-2) ◽  
pp. 157-174 ◽  
Author(s):  
Robert G. Wright
Keyword(s):  
United States ◽  
The United States ◽  
Southeast Asian ◽  
The World ◽  
Southeast Asian Refugee ◽  
Almost All ◽  
Voluntary Agencies

In almost all of the countries in the world which offer permanent resettlement to refugees, resettlement is accomplished through some combination of the efforts of government and voluntary agencies. This article identifies the elements of resettlement, and the various distributions of responsibility for its accomplishment. By focusing on the Southeast Asian refugee movement to the United States, current and evolving relationships among government and voluntary agencies are illustrated.

scholarly journals Comparative analyses revealed reduced spread of COVID-19 in malaria endemic countries

2020 ◽  
Author(s):  
Azhar Muneer ◽  
Kiran Kumari ◽  
Manish Tripathi ◽  
Rupesh Srivastava ◽  
Asif Mohmmed ◽  
...  
Keyword(s):  
Case Fatality ◽  
Protozoan Parasite ◽  
Death Rates ◽  
Healthcare Facilities ◽  
Malaria Endemicity ◽  
Health Infrastructure ◽  
The World ◽  
Fast Spreading ◽  
Almost All ◽  
Heterologous Protection

In late 2019, SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) infection started in Hubei province of China and now it has spread like a wildfire in almost all parts of the world except some. WHO named the disease caused by SARS-CoV-2 as COVID-19 (CoronaVirus Disease-2019). It is very intriguing to see a mild trend of infection in some countries which could be attributed to mitigation efforts, lockdown strategies, health infrastructure, demographics and cultural habits. However, the lower rate of infection and death rates in mostly developing countries, which are not placed at higher levels in terms of healthcare facilities, is a very surprising observation. To address this issue, we hypothesize that this lower rate of infection is majorly been observed in countries which have a higher transmission/prevalence of protozoan parasite borne disease, malaria. We compared the COVID-19 spread and malaria endemicity of 108 countries which have shown at least 200 cases of COVID-19 till 18th April 2020. We found that the number of COVID-19 cases per million population correlates negatively with the malaria endemicity of respective countries. The malaria free countries not only have higher density of COVID-19 infections but also the higher case fatality rates as compared to highly malaria endemic countries. We also postulate that this phenomenon is due to natural immune response against malaria infection, which is providing a heterologous protection against the virus. Unfortunately, there is no licensed vaccine against SARS-CoV-2 yet, but this information will be helpful in design of future strategies against fast spreading COVID-19 disease.

scholarly journals Mother Nature’s Revolution and the COVID-19 Pandemic: A Scooping Review of COVID-19 and the Environment

2021 ◽  
Vol 17 (19) ◽  
pp. 100
Author(s):  
Endurance Uzobo ◽  
Stanley E. Boroh
Keyword(s):  
United States Of America ◽  
Negative Impact ◽  
The United States ◽  
Online News ◽  
Web Pages ◽  
Web Page ◽  
Environmental Behaviour ◽  
Secondary Sources ◽  
The World ◽  
Almost All

Many studies have solely focused on the negative impact of the coronavirus while ignoring the fact that the coronavirus was also a blessing in disguise to certain institutions. This study focuses on an exploration of some of the environmental-related benefits accruing from the outbreak of the coronavirus, which eventually led many countries of the world to declare a national lockdown. The study utilised secondary sources from 21 articles gleaned from hand-searched literature from various web pages and online news, accessed through google web page (google.com) between March to September 2020. Key search words used in the search were COVID-19 and the environment, benefits of COVID-19 to the environment, the environmental impact of COVID-19, and the environmental behaviour during COVID-19. The study reported that some positive benefits of COVID-19 concerning the environment from China, the United States of America, Europe, and Africa. Findings from the review indicated that almost all the continents in the world have experienced improve environmental quality as a result of the outbreak of the coronavirus. The study further added that one of the most important dividends arising from the outbreak is the positive change in behaviour in people towards the environment. It was, therefore, recommended that there is a need for nations of the world to leverage the window of opportunity provided by the coronavirus to encourage green economic behaviour to save the environment.

scholarly journals A study of Neospora caninum antibody seroprevalence ın dairy cows in Turkey

2020 ◽  
Vol 71 (1) ◽  
pp. 2018
Author(s):  
S. KASAP ◽  
S. ERTUNC ◽  
E. M. TEMIZEL ◽  
S. SENTURK
Keyword(s):  
Blood Serum ◽  
Dairy Cows ◽  
Neospora Caninum ◽  
Protozoan Parasite ◽  
Total Sample ◽  
Enzyme Linked Immunosorbent Assay ◽  
Marmara Region ◽  
Serum Samples ◽  
Caninum Antibody ◽  
Intracellular Protozoan Parasite

Neospora caninum is a intracellular protozoan parasite and is one of the major causes of repeated abortions, foetal malformations, pre-term deliveries, stillbirth and possible loss of milk yield in livestock. The presence of specific antibodies against N. caninum in the blood serum of dairy cows is investigated in the present study. A total of 184 blood serum samples of dairy cows were examined in Bursa province in the Marmara Region. N. caninum antibodies were measured using an indirect enzyme-linked immunosorbent assay (ELISA) (The Svanovir Neospora-Ab ELISA). From the total sample, antibodies to N. caninum were detected in 62 of the 184 examined cows (33.3%) and neurological findings were seen in a calf.

scholarly journals Investigation of Toxoplasma gondii Infection in Aborted Fetuses of Sheep Using PCR: A Study in North Khorasan Province, Iran

2020 ◽  
Vol 2020 ◽  
pp. 1-5
Author(s):  
Mitra Salehi ◽  
Hosein Nezami ◽  
Hamid Reza Niazkar
Keyword(s):  
Toxoplasma Gondii ◽  
Gestational Age ◽  
Protozoan Parasite ◽  
Abortion Rate ◽  
Obligate Intracellular ◽  
Significant Difference ◽  
Pcr Method ◽  
Toxoplasma Gondii Infection ◽  
Intracellular Protozoan Parasite

Toxoplasma gondii is a zoonotic obligate intracellular protozoan parasite that infects warm-blooded animals as well as humans worldwide. The purpose of this study was to delineate the prevalence of Toxoplasma infection in aborted fetuses of sheep in North Khorasan province, Iran. Three hundred and ninety-nine samples of the liver (133 samples), placenta (133 samples), and brain (133 samples) from 133 aborted fetuses of sheep were collected from 2015 to 2017. The ages of aborted fetuses were higher than 120 days’ gestational age in this study. According to the samples, sixteen out of 133 aborted fetuses of sheep were infected with T. gondii. Toxoplasma DNA was found in the placenta (68.75%) and liver (31.25%) samples of infected fetuses using the PCR method. The highest and lowest rates of Toxoplasma infection were observed during 2016 and 2017, respectively. Shirvan and Faruj provinces were recognized as the two most infected districts among others. There was a significant difference between the year and abortion rate in sheep due to infection by the Toxoplasma parasite (P<0.05). Furthermore, no significant difference between the prevalence of T. gondii infection and aborted fetuses was seen (P>0.05) in different areas. According to the present study, T. gondii infection can be one of the causes of fetus abortion of sheep in North Khorasan province, Iran.

scholarly journals In Astrocytes the Accumulation of the Immunity-Related GTPases Irga6 and Irgb6 at the Vacuole ofToxoplasma gondiiIs Dependent on the Parasite Virulence

2013 ◽  
Vol 2013 ◽  
pp. 1-10
Author(s):  
Felix P. Lubitz ◽  
Daniel Degrandi ◽  
Klaus Pfeffer ◽  
Anne K. Mausberg
Keyword(s):  
Protozoan Parasite ◽  
Obligate Intracellular ◽  
Virulent Strains ◽  
Resistance System ◽  
A Cell ◽  
The Central Nervous System ◽  
Low Levels ◽  
The Individual ◽  
Common Infection ◽  
Intracellular Protozoan Parasite

Toxoplasma gondiiis an obligate intracellular protozoan parasite responsible for a common infection of the central nervous system. Interferon (IFN)γis the key cytokine of host defence againstT. gondii. However,T. gondiistrains differ in virulence andT. gondiifactors determining virulence are still poorly understood. In astrocytes IFNγprimarily induces immunity-related GTPases (IRGs), providing a cell-autonomous resistance system. Here, we demonstrate that astrocytes prestimulated with IFNγinhibit the proliferation of various avirulent, but not virulent,T. gondiistrains. The two analyzed immunity-related GTPases Irga6 and Irgb6 accumulate at the PV only of avirulentT. gondiistrains, whereas in virulent strains this accumulation is only detectable at very low levels. Both IRG proteins could temporarily be found at the same PV, but did only partially colocalize. Coinfection of avirulent and virulent parasites confirmed that the accumulation of the two analyzed IRGs was a characteristic of the individual PV and not determined by the presence of other strains ofT. gondiiin the same host cell. Thus, in astrocytes the accumulation of Irga6 and Irgb6 significantly differs between avirulent and virulentT. gondiistrains correlating with the toxoplasmacidal properties suggesting a role for this process in parasite virulence.

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