scholarly journals Plasma cell gingivitis - an unusual case of simultaneus disease occurence in two siblings

2019 ◽  
Vol 76 (1) ◽  
pp. 81-85
Author(s):  
Milanko Djuric ◽  
Tanja Veljovic ◽  
Ivana Gusic ◽  
Jelena Mirnic ◽  
Nada Vuckovic ◽  
...  
Keyword(s):  
Case Report ◽  
Plasma Cell ◽  
Inflammatory Reaction ◽  
Unusual Case ◽  
Plasma Cells ◽  
Clinical Manifestations ◽  
Chewing Gum ◽  
Systemic Diseases ◽  
Disease Etiology ◽  
Clinical Appearance

Introduction. Plasma cell gingivitis (PCG) is a relatively rare disease that usually occurs on the anterior maxillary and mandibular gingiva. It manifests as extreme redness, swelling and gum tissue enlargement with propensity for bleeding, accompanied by extensive infiltration of plasma cells in the lamina propria. While the disease etiology remains unclear, its presentation is mostly attributed to nonspecific inflammatory reaction to certain foodstuffs or ingredients in oral hygiene products. Case report. A 9-year-old boy and 11-year-old girl were brought for exam by their mother because of fiery red lesions on the gingiva. The lesions had the same clinical features and identical localization and were concomitantly present in both siblings. After excluding other oral or systemic diseases with similar clinical manifestations, a diagnosis of PCG was established (most likely due to chewing gum). Conclusion. While beeing a purely benign, the PCG clinical appearance may mask much more detrimental conditions. Consequently, each such lesion requires due attention. To date, familial tendency for the development of such a condition has not been reported.

scholarly journals Excess of Plasma Cells with Pseudo-Gaucher Cells in a Case of Tuberculosis - A Case Report

2013 ◽  
Vol 9 (2) ◽  
pp. 30-32
Author(s):  
A Palta ◽  
P Dhiman ◽  
J Ram
Keyword(s):  
Bone Marrow ◽  
Case Report ◽  
Inflammatory Reaction ◽  
Lung Diseases ◽  
Plasma Cells ◽  
Bone Marrow Examination ◽  
Lytic Lesion ◽  
Rare Finding ◽  
Antitubercular Treatment ◽  
Chronic Inflammatory Reaction

This report describes a case of 50 year old woman fever and bony pains with lytic lesion in skull. A polyclonal band was seen in γregion on serum electrophoresis. Bone marrow examination showed excess of plasma cells along with many Pseudo- Gaucher cells. The diagnosis of chronic inflammatory reaction was made. Although stain for AFB was negative, the patient responded to antitubercular treatment. The presence of pseudo-gaucher cells along with plasmacytosis is a rare finding in tuberculosis. SAARC Journal of Tuberculosis, Lung Diseases & HIV/AIDS; 2012; IX(2) 30-32 DOI: http://dx.doi.org/10.3126/saarctb.v9i2.7976

scholarly journals Extramedullary Plasmacytoma of the Tonsil

2011 ◽  
Vol 2011 ◽  
pp. 1-2 ◽  
Author(s):  
Kevin C. Huoh ◽  
Annemieke Van Zante ◽  
David W. Eisele
Keyword(s):  
Plasma Cell ◽  
Unusual Case ◽  
Plasma Cells ◽  
Tertiary Care ◽  
Neck Region ◽  
Extramedullary Plasmacytoma ◽  
University Hospital ◽  
Rare Form ◽  
Head And Neck Region ◽  
Radiologic Evaluation

Plasma cell tumors are a diverse group of neoplasms characterized by monoclonal proliferation of plasma cells. Extramedullary plasmacytoma (EMP) is a rare form of localized plasma cell tumor that arises most often in the head and neck region. We present an unusual case of EMP of the palatine tonsil from a tertiary care university hospital. We discuss the histopathologic and radiologic evaluation as well as treatment of EMP.

The unusual case of neck lymphadenopathy - oculoglandular form of tularemia

2018 ◽  
Vol 7 (2) ◽  
pp. 1-5
Author(s):  
Katarzyna Baranowska-Kempisty ◽  
Jolanta Kluz-Zawadzka ◽  
Sylwia Warzybok-Bajda ◽  
Krzysztof Szuber
Keyword(s):  
Adverse Effect ◽  
Case Report ◽  
Francisella Tularensis ◽  
Unusual Case ◽  
Drug Research ◽  
Delayed Diagnosis ◽  
Clinical Manifestations ◽  
Elisa Test ◽  
Gram Negative ◽  
The Right

Tularemia is anthropozoonosis caused by Bacteria Francisella tularensis a gram negative, non-motile aerobic bacillus.[5][8] The bacteria is transmitted mostly by rabbits, hares, rodents and arthropods. The pathogen penetrates into an organism via damaged skin, conjunctiva or mucosa- either through inhalation or ingestion. The clinical manifestations depend on the route of acquisition. Six forms of the disease can be distinguished: ulceroglandular or glandular, oculoglandular, oropharyngeal, respiratory, typhoidal, and intestinal. [11] We present a case report of the rarest oculoglandular form of tularemia. The patient was admitted to the hospital with right pre-auricular swelling, right sided neck lymphadenopathy, conjunctivitis and a nodule of the right eyelid. After excluding more common differential diagnoses, an ELISA test was performed and Francisella tularensis antibodies were identified. Patient administered proper antibiotic therapy. Tularemia is a rarely occurring disease in Poland and is nearly never taken into consideration by otolaryngologists when diagnosing patients with neck lymphadenopathy. In clinical practice, otorhinolaryngologists should always consider this infectious zoonosis, especially the oculoglandular and oropharyngeal forms, as delayed diagnosis and treatment may causes serious health consequences in patients. In the future new drug research should be conducted because of the adverse effect of widely used medications specially for children and pregnant woman.

scholarly journals Localized IgG4-related disease manifested on the tongue: a case report

2021 ◽  
Vol 126 (1) ◽  
Author(s):  
Helya Hashemi ◽  
Andreas Thor ◽  
Erik Hellbacher ◽  
Marie Carlson ◽  
Miklós Gulyás ◽  
...  
Keyword(s):  
Case Report ◽  
Oral Mucosa ◽  
Plasma Cells ◽  
Clinical Manifestations ◽  
Assessment System ◽  
Immunoglobulin G4 ◽  
Related Disease ◽  
Multiple Organs ◽  
Igg4 Related Disease ◽  
Initial Symptoms

Immunoglobulin G4-related disease (IgG4-RD) is an immune-mediated fibroinflammatory condition that can affect multiple organs. IgG4-RD may show a variety of initial symptoms. In the oral mucosa, lesions present as inflammatory fibrosis with a large number of IgG4-positive plasma cells. Evaluating treatment is a well-known problem in IgG4-RD due to the absence of an established assessment system. There are difficulties in defining the severity of the disease, which is why treatment is primarily based on its clinical manifestations. We present a case report of localized IgG4-RD with ulcerative and proliferative manifestations on the tongue, which clinically mimicked oral squamous cell carcinoma. A tumor-like lesion on the tongue can indicate something else other than the malignant or reactive changes commonly found in the oral mucosa. Multiple differential diagnoses of these atypical oral lesions, including localized IgG4-RD, should be considered.

A RARE CASE PRESENTATION OF PRIMARY PLASMA CELL LEUKEMIA WITH REVIEW OF LITERATURE, A CASE REPORT

2021 ◽  
pp. 21-22
Author(s):  
Gaurav Sharma ◽  
Smita Sharma
Keyword(s):  
Case Report ◽  
Plasma Cell ◽  
Peripheral Blood ◽  
Plasma Cells ◽  
Plasma Cell Leukemia ◽  
Rare Entity ◽  
Cell Leukemia ◽  
Case Presentation ◽  
Blood Examination ◽  
Primary Plasma Cell Leukemia

Introduction: Primary Plasma Cell Leukemia (pPCL) is Plasma cell dyscrasia subtype which is rare and aggressive. It carries very poor prognosis. It has unique clinical and laboratory prole. Its rst clinical presentation is leukemia. Peripheral blood examination shows circulating mature looking yet clonal, plasma cells. On molecular and cytogenetic examinations, many aberrations are seen which are unique and make it a distinct entity different from traditional Multiple Myeloma (MM). Case presentation: 37 yr old Indian female presented with difculty in breathing for last 3 months and was initially evaluated for cardiac function & COVID-19 screening. Peripheral blood examination revealed circulating plasma cells. Bone marrow apirate conrmed the initial diagnosis of pPCL. She received BIODRONATE + Inj. BORTEZOMIB + Inj. CYCLOPHOSPHAMIDE + Tab Dexa and was advised for PETscan and skeletal survey. But due to nancial constraints, family decided to go for complete systemic workup in next phase of chemotherapy cycle. She was discharged with advise to be in close follow up and to complete her treatment cycles. Discussion: pPCL needs to be diagnosed promptly to formulate optimal intensive therapy. This atypical presentation with shortness of breath of rare entity of pPCLin such young age emphasizes the need for quick and thorough initial workup. Conclusion: Because of rarity of this disease, there is paucity of literature from India and especially the impact of the standard therapies in resource poor countries. Our case report highlights these challenges for conclusive management of this rare entity

scholarly journals The Early Diagnostic Dilemma in Angioimmunoblastic T Cell Lymphoma with Excessive Plasma Cells Proliferation

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Chunyan Wang ◽  
Xia Mao ◽  
Songya Liu ◽  
Cheng He ◽  
Ying Wang ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
T Cell ◽  
Plasma Cell ◽  
Plasma Cells ◽  
Cell Lymphoma ◽  
Clinical Manifestations ◽  
Underlying Disease ◽  
T Cell Lymphoma ◽  
Diagnostic Dilemma ◽  
Angioimmunoblastic T Cell Lymphoma

Background. Angioimmunoblastic T cell lymphoma (AITL) is an aggressive Epstein–Barr virus-associated T cell lymphoma. Clinical syndromes of AITL are not confined to fever and lymphadenopathy, and patients may initially present with polyclonal plasma cell proliferation, which may obscure the underlying disease of AITL, delaying diagnosis. Case Presentation. Here, we report two AITL patients with excessive plasma cell proliferation in the bone marrow, peripheral blood, and ascites even mimicking plasma cell leukemia. Both of them had poor endings. Conclusions. Our report emphasizes the complexity of the clinical manifestations of AITL, which aims to increase the alertness of physicians and improve the rate of early diagnosis. Integrated diagnostic approaches such as histopathology, flow cytometry, cytogenetics, and molecular biology are essential for accurate diagnosis and precise therapy.

scholarly journals Plasma Cell Gingivitis as a Predisposing Factor for Plaque-Induced Periodontitis: A Case Report

2021 ◽  
pp. 71-74
Author(s):  
Vilma Alejandra Umanzor Bonilla ◽  
Claudette Arambú ◽  
Hugo Romero ◽  
Juan Jose Guifarro
Keyword(s):  
Case Report ◽  
Connective Tissue ◽  
Plasma Cell ◽  
Plasma Cells ◽  
Benign Lesion ◽  
Unknown Etiology ◽  
Histopathological Study ◽  
Predisposing Factor ◽  
Gingival Bleeding ◽  
Gingival Enlargement

Plasma cell gingivitis is a benign lesion of unknown etiology characterized by massive infiltration of plasma cells into the connective tissue of the gingiva. Clinically it presents as a gingival enlargement with erythema and some areas with the presence of desquamation, it is usually asymptomatic, but on some occasions the patient may present pain and gingival bleeding. Diagnosis requires clinical-pathological correlation. Based on the foregoing, we present a case report of a 25-year-old female patient diagnosed with plasma cell gingivitis with idiopathic etiology based on the clinical and histopathological study.

scholarly journals A case of CD10-negative angioimmunoblastic T cell lymphoma with leukemic change and increased plasma cells mimicking plasma cell leukemia: A case report

2015 ◽  
Vol 10 (3) ◽  
pp. 1555-1560 ◽  
Author(s):  
YASUSHI ADACHI ◽  
TAKUYA HINO ◽  
MASAHIKO OHSAWA ◽  
KAZUHITO UEKI ◽  
TOMOKO MURAO ◽  
...  
Keyword(s):  
Case Report ◽  
T Cell ◽  
Plasma Cell ◽  
Plasma Cells ◽  
Cell Lymphoma ◽  
T Cell Lymphoma ◽  
Plasma Cell Leukemia ◽  
Cell Leukemia ◽  
Angioimmunoblastic T Cell Lymphoma

scholarly journals Primary Plasma Cell Leukaemia: Case report and review of the literature

2018 ◽  
Vol 18 (3) ◽  
pp. 397
Author(s):  
Sarika Singh ◽  
Ashutosh Rath ◽  
Surekha Yadav
Keyword(s):  
Case Report ◽  
Plasma Cell ◽  
Plasma Cells ◽  
Renal Involvement ◽  
Specific Treatment ◽  
Peripheral Blood Smear ◽  
Cell Leukaemia ◽  
Plasma Cell Dyscrasia ◽  
Diagnostic Features ◽  
Plasma Cell Leukaemia

Plasma cell leukaemia (PCL) is one of the most aggressive and rarest forms of plasma cell dyscrasia. However, the diagnostic criteria for this condition have not yet been revised and there is no specific treatment to significantly improve the course of the disease. We report a 69-year-old male who presented to the Lok Nayak Hospital, New Delhi, India, in 2017 with dyspnoea and chest pain. A peripheral blood smear showed an absolute plasma cell count of 2.16 × 109/L. A bone marrow examination showed 61% atypical plasma cells exhibiting kappa light chain restriction. Biochemical investigations were consistent with a diagnosis of primary PCL with renal involvement. Bortezomib-based chemotherapy was initiated, which resulted in an improvement in the patient’s haematological and biochemical parameters. This case report includes a comprehensive review of the clinical and diagnostic features, pathobiology and treatment of PCL.Keywords: Plasma Cell Leukemia; Multiple Myeloma; Plasma Cells; Case Report; India.

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