Discovery and Teaching a Body of Knowledge

1976 ◽  
Vol 5 (3) ◽  
pp. 191 ◽  
Author(s):  
Stephen I. Brown
Keyword(s):  
Body Of Knowledge

Characterization of the Original Christmas Disease Mutation (Cysteine 206 → Serine): From Clinical Recognition to Molecular Pathogenesis

1992 ◽  
Vol 67 (01) ◽  
pp. 063-065 ◽  
Author(s):  
Sherryl A M Taylor ◽  
Jacalyn Duffin ◽  
Cherie Cameron ◽  
Jerome Teitel ◽  
Bernadette Garvey ◽  
...  
Keyword(s):  
Nucleotide Substitution ◽  
Novel Mutation ◽  
Factor Ix ◽  
Causative Mutation ◽  
Coding Region ◽  
Body Of Knowledge ◽  
Polymerase Chain ◽  
Splice Junctions

SummaryChristmas disease was first reported as a distinct clinical entity in two manuscripts published in 1952 (1, 2). The eponym associated with this disorder, is the surname of the first patient examined in detail and reported by Biggs and colleagues in a paper describing the clinical and laboratory features of seven affected individuals (3). This patient has severe factor IX coagulant deficiency (less than 0.01 units/ml) and no detectable circulating factor IX antigen (less than 0.01 units/ml). Coding sequence and splice junctions of the factor IX gene from this patient have been amplified in vitro through the polymerase chain reaction (PCR). One nucleotide substitution was identified at nucleotide 30,070 where a guanine was replaced by a cytosine. This mutation alters the amino acid encoded at position 206 in the factor IX protein from cysteine to serine. The non conservative nature of this substitution, the absence of this change in more than 200 previously sequenced factor IX genes and the fact that the remainder of the coding region of this gene was normal, all provide strong circumstantial evidence in favour of this change being the causative mutation in this patient. The molecular characterization of this novel mutation in the index case of Christmas disease, contributes to the rapidly expanding body of knowledge pertaining to Christmas disease pathogenesis.

Meanings of burnout and resilience in Ontario dietitians

2012 ◽  
Vol 1 (2) ◽  
pp. 13-20
Author(s):  
Yuka Asada
Keyword(s):  
Job Stress ◽  
Professional Growth ◽  
Maslach Burnout Inventory ◽  
Professional Relationships ◽  
Contributing Factors ◽  
Dietetic Education ◽  
Body Of Knowledge ◽  
Growth And Change ◽  
And Training ◽  
Preventative Approach

  ABSTRACT   Objectives: Although experiences of burnout are well documented among some health professionals, there is limited research that explores similar experiences among dietitians. This study aims (1) to describe the varied qualitative dimensions of burnout that are particular to dietitians and (2) to identify the factors that might be deemed protective against burnout. Methods: Fourteen dietitians were recruited from a larger quantitative study that assessed prevalence of burnout in Ontario, Canada using the Maslach Burnout Inventory (MBI). Those who completed the MBI were invited to participate in two phenomenological interviews. Transcribed interviews were analyzed by naïve readings and identified meaning units with a larger team for increased rigor and trustworthiness. Results: Dietitians describe burnout as having bodily and overall health consequences. Both social/professional relationships and dietitians’ passion for their work contributed to experiences of burnout and resilience. Opportunities for continued professional growth and change were contributing factors for resilience. Implications & Conclusions: This study contributes to the limited body of knowledge on dietitians’ lived experiences of burnout and resilience. The findings have implications for those involved in the education and training of student dietitians, and for those in a position to offer support to dietitians who are struggling with job stress. In the context of fostering resilience, a preventative approach to dietetic education is explored with the intention to protect future practitioners from burnout.

Every Detail Counts: Robert Stoller, Perversion and the Production of Pornography

2020 ◽  
Vol 22 (1) ◽  
pp. 35-52
Author(s):  
Jeffrey Escoffier
Keyword(s):  
Film Industry ◽  
Ethnographic Study ◽  
Systematic Method ◽  
Body Of Knowledge ◽  
Sexuality And Gender ◽  
Pornographic Film ◽  
And Gender ◽  
Do So

After the publication of his pioneering book Sexual Excitement in 1979, Robert Stoller devoted the last 12 years of his life to the study of the pornographic film industry. To do so, he conducted an ethnographic study of people working in the industry in order to find out how it produced ‘perverse fantasies’ that successfully communicated sexual excitement to other people. In the course of his investigation he observed and interviewed those involved in the making of pornographic films. He hypothesized that the ‘scenarios’ developed and performed by people in the porn industry were based on their own perverse fantasies and their frustrations, injuries and conflicts over sexuality and gender; and that the porn industry had developed a systematic method and accumulated a sophisticated body of knowledge about the production of sexual excitement. This paper explores Stoller's theses and shows how they fared in his investigation.

Knowledge creation in small building and construction firms

2013 ◽  
Vol 1 (1) ◽  
pp. 125-142 ◽  
Author(s):  
Susanne Durst ◽  
Ingi Runar Edvardsson ◽  
Guido Bruns
Keyword(s):  
Construction Industry ◽  
Knowledge Creation ◽  
Vital Role ◽  
Knowledge Sources ◽  
Structured Interviews ◽  
Construction Firms ◽  
External Knowledge ◽  
Body Of Knowledge ◽  
Small Building

Studies on knowledge creation are limited in general, and there is a particular shortage of research on the topic in small and medium-sized enterprises (SMEs). Given the importance of SMEs for the economy and the vital role of knowledge creation in innovation, this situation is unsatisfactory. Accordingly, the purpose of our study is to increase our understanding of how SMEs create new knowledge. Data are obtained through semi-structured interviews with ten managing directors of German SMEs operating in the building and construction industry. The findings demonstrate the influence of external knowledge sources on knowledge creation activities. Even though the managing directors take advantage of different external knowledge sources, they seem to put an emphasis on informed knowledge sources. The study´s findings advance the limited body of knowledge regarding knowledge creation in SMEs.

A Stellenbosch University #FeesMustFall Herstory: Reflections of a So-Called "Radical Black Intersectional Feminist"

Politeia ◽  
2018 ◽  
Vol 37 (2) ◽  
Author(s):  
Ashanti Kunene
Keyword(s):  
The Body ◽  
Self Reflection ◽  
Body Of Knowledge ◽  
Patriarchal Narratives

#FeesMustFall was a movement whose maxim was, “This revolution will be intersectional, or it will be bullshit.” This article is a self-reflection on my participation as a so-called radical black intersectional feminist in the #FeesMustFall movement at Stellenbosch University. It is also an attempt to provide evidence of the double erasures taking place in the mainstream patriarchal narratives about the #FeesMustFall movement. My story bears witness to the fact that queer black womxn were the backbone of the movement and that #FeesMustFall did indeed occur at Stellenbosch University. These constitute the double erasures taking place in terms of what is and can be known about the #FeesMustFall movement. My reflections serve to make a much-needed contribution to the body of knowledge produced about the #FeesMustFall movement.

Employees Attitude towards E-Learning in Banking Sector -An Empirical Study of Shivamogga District

2019 ◽  
Vol 118 (10) ◽  
pp. 88-106
Author(s):  
Dr.Mamatha. S.M ◽  
Mr.Panduranganagouda Honnali
Keyword(s):  
Banking Sector ◽  
Employee Performance ◽  
Private Bank ◽  
Public And Private ◽  
The Public ◽  
Body Of Knowledge ◽  
E Learning ◽  
Banking Structure ◽  
Bank Employees ◽  
Methods Of Learning

E-learning has become a global phenomenon and it is the central theme of many industries and organizations for the additional method of training which can complement traditional methods of learning. The practices of E-learning and Learning management system (LMS) in the banking sector make the drastic changes in the employee performance and their knowledge regarding job in the modern banking structure. This study provides a comprehensive body of knowledge about LMS and e-learning, in general, within the public and private bank in India. The main objective of this paper to understand and analyze the attitude of employees towards E-learning practices in banking sector in Shivamogga district. The data was analyzed by using exploratory factor analysis, based on the responses received from a random the sample 50 of the bank employees working in the private sector banks.

EXPLORING HEALTHCARE ARCHITECTURE THROUGH THE MEDIUM OF FILM: Motives and Techniques

2014 ◽  
Vol 8 (1) ◽  
pp. 29
Author(s):  
Stephen Verderber
Keyword(s):  
Real World ◽  
The Real ◽  
Healthcare Settings ◽  
Interdisciplinary Field ◽  
Body Of Knowledge ◽  
Behavior Setting ◽  
Physical Environments ◽  
Scant Attention ◽  
History Of

The interdisciplinary field of person-environment relations has, from its origins, addressed the transactional relationship between human behavior and the built environment. This body of knowledge has been based upon qualitative and quantitative assessment of phenomena in the “real world.” This knowledge base has been instrumental in advancing the quality of real, physical environments globally at various scales of inquiry and with myriad user/client constituencies. By contrast, scant attention has been devoted to using simulation as a means to examine and represent person-environment transactions and how what is learned can be applied. The present discussion posits that press-competency theory, with related aspects drawn from functionalist-evolutionary theory, can together function to help us learn of how the medium of film can yield further insights to person-environment (P-E) transactions in the real world. Sampling, combined with extemporary behavior setting analysis, provide the basis for this analysis of healthcare settings as expressed throughout the history of cinema. This method can be of significant aid in examining P-E transactions across diverse historical periods, building types and places, healthcare and otherwise, otherwise logistically, geographically, or temporally unattainable in real time and space.

Wertspeicher: Epistemologien des Warenlagers

2012 ◽  
Vol 3 (2) ◽  
Author(s):  
Monika Dommann
Keyword(s):  
Economic Crisis ◽  
Industrial Capitalism ◽  
Trade Cycle ◽  
New Era ◽  
Body Of Knowledge

Der Text geht von der These aus, dass nicht, wie oft behauptet, eine Virtualisierung, sondern eine Vergegenständlichung und Materialisierung den Kapitalismus auszeichnet. Dabei werden Warenlager als materialisierte Form des industriellen Kapitalismus hinsichtlich ihrer epistemischen Produktivkraft untersucht. Im Zentrum steht dabei die Entstehung eines neuen handelswissenschaftlichen und volkswirtschaftlichen Wissenskorpus, das in die Praxis der Warenlagerung interveniert. Nach der Weltwirtschaftskrise von 1920/21 wird die Vorratshaltung in Frage gestellt und es beginnt eine neue Epoche der Warenlagerwissenschaften, deren Folgen auch bei der Formulierung von Konjunkturtheorien thematisiert werden. </br></br>The paper presents the thesis that, in contrast to the conventional claim, capitalism is not characterized by virtualization, but by objectification and materialization. As materialized forms of industrial capitalism, warehouses are investigated with regard to their epistemic productivity. Central for the argument is the emergence of a new body of knowledge concerning commercial and economic sciences, which figures decisively in the practice of warehousing. After the worldwide economic crisis of 1920/21, stockpiling is called into question and a new era of warehouse sciences begins, the consequences of which are also addressed in the formulation of trade cycle theories.

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