Efficacy of a Novel At-home Bleaching Technique With Carbamide Peroxides Modified by CPP-ACP and Its Effect on the Microhardness of Bleached Enamel

2011 ◽  
Vol 36 (5) ◽  
pp. 521-528 ◽  
Author(s):  
BCD Borges ◽  
JS Borges ◽  
CD de Melo ◽  
IVA Pinheiro ◽  
AJS dos Santos ◽  
...  
Keyword(s):  
Vickers Microhardness ◽  
Color Change ◽  
Artificial Saliva ◽  
Carbamide Peroxide ◽  
Peroxide Bleaching ◽  
Significant Difference ◽  
Casein Phosphopeptide ◽  
Shade Guide ◽  
At Home

SUMMARY This study was designed to evaluate in vitro the efficacy of a novel at-home bleaching technique using 10% or 16% carbamide peroxide modified by casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) and its influence on the microhardness of bleached enamel. A total of 40 bovine incisors were divided into four groups (n=10) according to the bleaching agent used: 10% carbamide peroxide only; a blend of 10% carbamide peroxide and a CPP-ACP paste; 16% carbamide peroxide only; and a blend of 16% carbamide peroxide and a CPP-ACP paste. During the 14-day bleaching regimen, the samples were stored in artificial saliva. The Vickers microhardness and color of the teeth were assessed at baseline (T0) and immediately after the bleaching regimen (T14) using a microhardness tester and a spectrophotometer, respectively. The degree of color change was determined by the Commission Internationale de l'Eclariage (CIE) L*a*b* system (ΔE, ΔL*, Δa*, and Δb*) and Vita shade guide parameters. The data were analyzed by analysis of variance and the Tukey test (p<0.05). The teeth that were bleached with a blend of peroxide (10% or 16%) and the CPP-ACP paste presented increased microhardness values at T14 compared with T0, whereas the samples that were bleached with peroxide only did not show any differences in their microhardness values. All of the bleaching agents were effective at whitening the teeth and did not show a statistically significant difference using the CIEL*a*b* system (ΔE, ΔL*, Δa*, and Δb*) or the Vita shade guide parameters. The use of a CPP-ACP paste with carbamide peroxide bleaching agents increased the bleached enamel's microhardness and did not have an influence on whitening efficacy.

Brushing Effect of Abrasive Dentifrices during At-home Bleaching with 10% Carbamide Peroxide on Enamel Surface Roughness

2006 ◽  
Vol 7 (1) ◽  
pp. 25-34 ◽  
Author(s):  
Luís Roberto Marcondes Martins ◽  
Claudia Cia Worschech ◽  
José Augusto Rodrigues ◽  
Gláucia Maria Bovi Ambrosano
Keyword(s):  
Surface Roughness ◽  
Artificial Saliva ◽  
Enamel Surface ◽  
Tooth Bleaching ◽  
Carbamide Peroxide ◽  
Peroxide Bleaching ◽  
Human Enamel ◽  
Over Time ◽  
At Home

Abstract During tooth bleaching abrasive dentifrices might change the outer superficial enamel. The aim of this in vitro study was to evaluate the roughness of human enamel exposed to a 10% carbamide peroxide bleaching agent at different times and submitted to different superficial cleaning treatments. The study consisted of 60 sound human enamel slabs, randomly assigned to different treatment groups: G1 - not brushed; G2 - brushed with a fluoride abrasive dentifrice; G3 - brushed with a non-fluoride abrasive dentifrice; and G4 - brushed without a dentifrice. There were 15 enamel slabs per group. Slabs of molar teeth were obtained and sequentially polished with sandpaper and abrasive pastes. A perfilometer was used to obtain the mean of Ra value on the surface of each specimen to initial and experimental times. Bleaching was performed on the enamel surface for six hours daily. After that, each slab received a cleaning surface treatment and was stored in artificial saliva. Analysis of variance (ANOVA) and Tukey's HSD hoc analysis (α =0.05) revealed significant differences in roughness values over time for enamel bleached and treated with different superficial cleaning methods. G1 and G4 showed no significant differences in roughness over time, G2 and G3 showed a significant increase in the surface roughness values. This in vitro investigation showed the sole use of 10% carbamide peroxide did not alter the enamel surface roughness, but the cleaning treatments that employed the use of brushing with abrasive dentifrices resulted in a significant increase of enamel surface roughness. Citation Worschech CC, Rodrigues JA, Martins LRM, Ambrosano GMB. Brushing Effect of Abrasive Dentifrices during At-home Bleaching with 10% Carbamide Peroxide on Enamel Surface Roughness. J Contemp Dent Pract 2006 February;(7)1:025-034.

scholarly journals EFEKTIVITAS EKSTRAK STROBERI DAN JERUK MADU DALAM PERUBAHAN WARNA GIGI SECARA IN VITRO

2021 ◽  
Vol 16 (1) ◽  
pp. 209-213
Author(s):  
Nalem Rika Rahayu
Keyword(s):  
Color Change ◽  
Laboratory Research ◽  
Carbamide Peroxide ◽  
Tooth Color ◽  
Sample Group ◽  
Tooth Discoloration ◽  
Significant Difference ◽  
Experimental Laboratory ◽  
Shade Guide

ABSTRACT   Changing tooth color affects a person's aesthetics. Methods to restore tooth discoloration include the use ofagents bleaching. This study aims to understand the differences in the effectiveness of strawberry and honey orange extracts intooth discoloration in vitro. This type of experimental laboratory research used 45 premolar tooth samples divided into 3 groups (50% strawberry extract and 10% carbamide peroxide concentration, 50% honey orange extract and 10% carbamide peroxide concentration and 10% carbamide peroxide concentration). Samples were immersed in coffee solution for 5 days and recorded color with a shade guide, then samples were immersed in the extract of strawberries, honey oranges and carbamide peroxide for 7 days in an incubator, then recorded color again visually with a shade guide. Data analysis used thestatistical tests Oneway Anova and Posthoc LSD. The color change of the sample group immersed in strawberry extract with carbamide peroxide resulted in a significant difference (p <0.05). Likewise, the sample group immersed in honey orange extract with carbamide peroxide produced a significant difference (p <0.05), but strawberries and honey oranges did not. there is not significant difference (p> 0.05). From the results of the study it can be concluded that the extracts of strawberries and honey oranges were able to increase the discoloration of teeth to become brighter, there was no significant difference between changes in tooth discoloration soaked in strawberry extract and honey orange.   ABSTRAK Warna gigi yang berubah mempengaruhi estetik seseorang, metode untuk mengembalikan perubahan warna gigi diantaranya dengan penggunakan bahan bleaching. Penelitian ini bertujuan untuk memahami perbedaan efektivitas ekstrak buah stroberi dan jeruk madu dalam perubahan warna gigi secara in vitro. Jenis penelitian eksperimental laboratoris menggunakan sampel gigi premolar sebanyak 45 buah dibagi atas 3 kelompok (ekstrak stroberi konsentrasi 50% dan karbamid peroksida konsentrasi 10%, ekstrak jeruk madu konsentrasi 50% dan karbamid peroksida konsentrasi 10% dan karbamid peroksida konsentrasi 10%). Sampel direndam larutan kopi selama 5 hari dan lakukan pencatatan warna dengan shade guide, kemudian sampel direndam ekstrak stroberi, jeruk madu dan karbamid peroksida selama 7 hari di dalam inkubator, lalu dilakukan pencatatan warna kembali secara visual dengan shade guide. Analisis data memakai uji statistik Oneway Anova dan Posthoc LSD. Perubahan warna kelompok sampel direndam ekstrak stroberi dengan karbamid peroksida menghasilkan perbedaan signifikan (p<0,05), begitu pula kelompok sampel yang direndam ekstrak jeruk madu dengan karbamid peroksida menghasilkan perbedaan signifikan (p<0,05), namun stroberi dan jeruk madu tidak ada perbedaan yang signifikan (p>0,05). Dari hasil penelitian dapat disimpulkan bahwa ekstrak  stroberi dan jeruk madu mampu meningkatkan perubahan warna gigi menjadi lebih terang, tidak ada perbedaan signifikan antara perubahan perubahan warna gigi yang direndam ekstrak stroberi dan jeruk madu.

scholarly journals Effect of thickener agents on dental enamel microhardness submitted to at-home bleaching

2007 ◽  
Vol 21 (2) ◽  
pp. 170-175 ◽  
Author(s):  
José Augusto Rodrigues ◽  
Glauco Paulo Felício Oliveira ◽  
Cristiane Mariote Amaral
Keyword(s):  
Oxidation Reaction ◽  
Artificial Saliva ◽  
Dental Enamel ◽  
Experimental Treatment ◽  
The Other ◽  
Carbamide Peroxide ◽  
Dental Bleaching ◽  
Mineral Loss ◽  
At Home

Dental bleaching occurs due to an oxidation reaction between the bleaching agents and the macromolecules of pigments in the teeth. This reaction is unspecific and the peroxides can also affect the dental matrix causing mineral loss. On the other hand, recent studies have suggested that the thickener agent carbopol can also cause mineral loss. Thus, the objective of this study was to evaluate in vitro the effect of at-home dental bleaching on dental enamel microhardness after the use of bleaching agents with and without carbopol as a thickener agent. Bovine dental slabs with 3 x 3 x 3 mm were obtained, sequentially polished, and randomly divided into 4 groups according to the experimental treatment: G1: 2% carbopol; G2: 10% carbamide peroxide with carbopol; G3: carbowax; G4: 10% carbamide peroxide with poloxamer. Bleaching was performed daily for 4 weeks, immersed in artificial saliva. Enamel microhardness values were obtained before the treatment (T0) and 7 (T1), 14 (T2), 21 (T3), 28 (T4), and 42 (T5) days after the beginning of the treatment. ANOVA and Tukey's test revealed statistically significant differences only for the factor Time (F = 5.48; p < 0.01). All bleaching and thickener agents caused no alterations on the enamel microhardness.

Effect of 10% and 15% Carbamide Peroxide on Fracture Toughness of Human Dentin In Situ

2013 ◽  
Vol 38 (2) ◽  
pp. 142-150 ◽  
Author(s):  
LE Tam ◽  
P Bahrami ◽  
O Oguienko ◽  
H Limeback
Keyword(s):  
Fracture Toughness ◽  
Placebo Group ◽  
Color Change ◽  
Carbamide Peroxide ◽  
Tooth Sensitivity ◽  
Custom Made ◽  
Dental Hard Tissues ◽  
Significant Difference

SUMMARY Purpose Although damage to the structural integrity of the tooth is not usually considered a significant problem associated with tooth bleaching, there have been some reported negative effects of bleaching on dental hard tissues in vitro. More studies are needed to determine whether the observed in vitro effects have practical clinical implications regarding tooth structural durability. Objectives This in situ study evaluated the effect of 10% and 15% carbamide peroxide (CP) dental bleach, applied using conventional whitening trays by participants at home, on the fracture toughness of dentin. Methods Ninety-one adult volunteers were recruited (n ≈ 30/group). Compact fracture toughness specimens (approximately 4.5 × 4.6 × 1.7 mm) were prepared from the coronal dentin of recently extracted human molars and gamma-radiated. One specimen was fitted into a prepared slot, adjacent to a maxillary premolar, within a custom-made bleaching tray that was made for each adult participant. The participants were instructed to wear the tray containing the dentin specimen with placebo, 10% CP, or 15% CP treatment gel overnight for 14 nights and to store it in artificial saliva when not in use. Pre-bleach and post-bleach tooth color and tooth sensitivity were also evaluated using ranked shade tab values and visual analogue scales (VASs), respectively. Within 24–48 hours after the last bleach session, the dentin specimens were tested for fracture toughness using tensile loading at 10 mm/min. Analysis of variance, Kruskal-Wallis, χ2, Tukey's, and Mann-Whitney U tests were used for statistical analysis. The level of significance was set at p&lt;0.05 for all tests, except for the Mann-Whitney U tests, which used a Bonferroni correction for post hoc analyses of the nonparametric data (p&lt;0.017). Results The placebo, 10% CP, and 15% CP groups contained 30, 31, and 30 participants, respectively. Mean fracture toughness (+ standard deviation) for the placebo, 10% CP, and 15% CP groups were 2.3 ± 0.9, 2.2 ± 0.7, and 2.0 ± 0.5 MPa*m1/2 respectively. There were no significant differences in mean fracture toughness results among the groups (p=0.241). The tooth sensitivity VAS scores indicated a significantly greater incidence (p=0.000) and degree of tooth sensitivity (p=0.049 for VAS change and p=0.003 for max VAS) in the bleach groups than in the placebo group. The color change results showed generally greater color change in the bleach groups than in the placebo group (p=0.008 for shade guide determination and p=0.000 for colorimeter determination). Conclusions There were no significant differences in in situ dentin fracture toughness results among the groups. The results of this study provide some reassurance that dentin is not overtly weakened by the bleaching protocol used in this study. However, the lack of a statistically significant difference cannot be used to state that there is no effect of bleach on dentin fracture toughness.

scholarly journals Effect of a carbamide peroxide bleaching gel containing calcium or fluoride on human enamel surface microhardness

2005 ◽  
Vol 16 (2) ◽  
pp. 103-106 ◽  
Author(s):  
Rogério de Oliveira ◽  
Adriana Franco Paes Leme ◽  
Marcelo Giannini
Keyword(s):  
Artificial Saliva ◽  
In Vitro Study ◽  
Enamel Surface ◽  
Control Group ◽  
Carbamide Peroxide ◽  
Surface Microhardness ◽  
Treatment Groups ◽  
Peroxide Bleaching ◽  
Human Enamel

This in vitro study evaluated the surface microhardness of human enamel submitted to bleaching with 10% carbamide peroxide (CP) containing calcium or fluoride. Ninety-eight dental blocks (5 x 5 mm²) with polished enamel surfaces were randomly assigned to 7 treatment groups (n=14), as follows: without bleaching and storage in artificial saliva (control); 10% CP; 10% CP + 0.05% calcium; 10% CP + 0.1% calcium; 10% CP + 0.2% calcium; 10% CP + 0.2% fluoride; and 10% CP + 0.5% fluoride. During 14 days, enamel surfaces were daily exposed to a 6-h bleaching regimen followed by storage in artificial saliva. Surface microhardness was measured before (baseline), during (7th day), immediately after bleaching (14th day) and 1 week post bleaching. Data were analyzed by two-way ANOVA and Tukey's test (p<0.05). All treatments reduced SM significantly during the bleaching cycle (7th day), immediately after bleaching (14th day) and 1 week post bleaching, compared to baseline and to the unbleached control group. In conclusion, in spite of the addition of calcium and fluoride, all bleaching treatments affected the enamel surface microhardness.

At-home Bleaching With 10% vs More Concentrated Carbamide Peroxide Gels: A Systematic Review and Meta-analysis

2018 ◽  
Vol 43 (4) ◽  
pp. E210-E222 ◽  
Author(s):  
JL de Geus ◽  
LM Wambier ◽  
TF Boing ◽  
AD Loguercio ◽  
A Reis
Keyword(s):  
Systematic Review ◽  
Lower Risk ◽  
Color Change ◽  
Research Question ◽  
Cochrane Collaboration ◽  
Risk Of Bias ◽  
Cochrane Library ◽  
Carbamide Peroxide ◽  
Significant Difference ◽  
At Home

SUMMARY Objective: To perform a systematic review to answer the following research question: Is at-home bleaching in adults with more concentrated carbamide peroxide (CP) gels as effective and safe as bleaching performed with 10% carbamide peroxide gels? Methods and Materials: A comprehensive search was carried out in the MEDLINE via PubMed, Scopus, Web of Science, LILACS, BBO, Cochrane Library and SIGLE, without restrictions. IADR abstracts (1990 to 2016) and unpublished and ongoing trial registries, dissertations and theses (ProQuest Dissertations and Periodicos Capes Theses Databases) were also searched. The risk of bias of the included studies was analyzed using the Cochrane Risk of Bias tool from the Cochrane Collaboration. We meta-analyzed the data using the random effects model to compare 10% CP and more concentrated CP gels in terms of color change (ΔSGU or ΔE) and risk and intensity of tooth sensitivity (TS). The quality of the evidence was rated using the GRADE approach. Results: After the database screening, 182 articles remained, and this number was reduced to 17 after examination of the abstracts and/or full texts. Four articles were follow-ups of earlier studies, and thus we collected 13 studies. Ten studies were at unclear risk of bias, while three were at low risk of bias. Lower risk and intensity of TS was observed for 10% CP. The odds ratio for the risk of TS was 0.41 (95% CI 0.20 to 0.84, p=0.01), and the difference in means for TS intensity was 0.44 (95% CI 0.67 to −0.20, p=0.0003). No significant difference was observed in terms of color change in ΔSGU (difference in means 0.29; 95% CI 0.25 to 0.83, p=0.29) and for ΔE (difference in means −0.16; 95% CI 0.38 to 0.06, p=0.16). Except from the ΔSGU, for which the evidence was graded as low quality, the other outcomes were considered at moderate quality. Conclusions: At-home bleaching with 10% CP showed similar bleaching efficacy with lower risk and intensity of TS in comparison with more concentrated carbamide peroxide gels.

scholarly journals Is An Orthodontic Hydrophilic Composite Resistant to Contamination and pH Cycling? In vitro Results

2020 ◽  
Vol 14 (1) ◽  
pp. 608-614
Author(s):  
Paula Patrícia Primo ◽  
Karina Maria Salvatore Freitas ◽  
Daniela Fernandes Ceron ◽  
Paula Cotrin ◽  
Renata Cristina Oliveira ◽  
...  
Keyword(s):  
Bond Strength ◽  
Adhesive Strength ◽  
Shear Bond Strength ◽  
Color Change ◽  
Artificial Saliva ◽  
Chi Square ◽  
Intergroup Comparison ◽  
Significant Difference ◽  
Ph Cycling

Objective: To evaluate the adhesive strength of a hydrophilic composite submitted to contamination and pH cycling, compared to a conventional composite. Materials and Methods: Seventy-two bovine incisors were prepared and randomly divided into 6 groups (n=12), bonded with Hydrophilic Composite (HC)(Transbond Plus Color Change) or with Conventional Composite (CC)(Transbond XT; control), with or without contamination and pH cycling as follows: G1-HC, with contamination, with pH cycling; G2-HC, with contamination, without pH cycling; G3-HC, without contamination, with pH cycling; G4-HC, without contamination, without pH cycling; G5-CC, without contamination, with pH cycling; G6-CC, without contamination, without pH cycling. Contamination in G1 and G2 consisted of fresh saliva applied after the self-etching primer for 5min before bonding with HC. After bonding, G1, G3, and G5 were submitted to pH cycling, immersed in the demineralizing solution for 22h and for 2h in remineralizing artificial saliva, repeated for 15 days. G2, G4, and G6 were kept in deionized water. The shear bond strength was tested using a load cell of 100N and the Adhesive Remnant Index (ARI) was assessed. Intergroup comparison was performed with one-way ANOVA, Tukey, and chi-square tests. Results: There was a statistically significant difference in G1, G2, and G3 in relation to G6. The highest rate of adhesive failure between the resin/bracket interface occurred with the HC, while CC failed more at the resin/tooth interface. Conclusion: Contamination and pH cycling did not decrease the shear bond strength of brackets bonded with the hydrophilic composite. However, the adhesive strength of the conventional composite was higher.

scholarly journals Effectiveness and Impact of the Walking Bleach Technique on Esthetic Self-perception and Psychosocial Factors: A Randomized Double-blind Clinical Trial

2017 ◽  
Vol 42 (6) ◽  
pp. 596-605 ◽  
Author(s):  
C Bersezio ◽  
J Martin ◽  
F Peña ◽  
M Rubio ◽  
J Estay ◽  
...  
Keyword(s):  
Hydrogen Peroxide ◽  
Psychosocial Factors ◽  
Color Change ◽  
Carbamide Peroxide ◽  
Self Perception ◽  
Dental Esthetics ◽  
Tooth Discoloration ◽  
Significant Difference ◽  
The Impact ◽  
Shade Guide

SUMMARY Objective: This trial evaluates the impact of psychosocial and esthetic self-perceptions of patients undergoing nonvital tooth bleaching using the walking bleach technique. We also assessed the clinical effectiveness of bleaching tooth discoloration. Methods: Fifty volunteers with nonvital tooth discoloration were enrolled. Teeth were randomized into two groups: 35% hydrogen peroxide (n=25) and 37% carbamide peroxide (n=25). Intracoronal bleaching was performed over four sessions using the walking bleach technique. Tooth color was evaluated at each session to measure total color variation. The shade guide was arranged from highest (B1) to lowest (C4) values to assess the color and calculate the color change in the number of shade guide units. Subjective and objective assessments were compared with the tooth counterpart. Esthetic self-perception and psychosocial factors were assessed before and after treatment. Results: Color change was 15.48&lt;5.17 for hydrogen peroxide and 14.02&lt;4.85 for carbamide peroxide. There was no significant difference at any time point (p&gt;0.05) except at sessions 3 and 4 (p&lt;0.05). Overall, whitened teeth values were similar to those of counterpart teeth (p&gt;0.05). There was a decrease in Oral Health Impact Profile and Psychosocial Impact of Dental Esthetics questionnaire scores after treatment compared with baseline (p&lt;0.05). Conclusion: The walking bleach technique was highly effective on nonvital teeth and had a positive effect on self-esthetic perception and psychological impact for the patients.

scholarly journals Combined Bleaching Technique Using Low and High Hydrogen Peroxide In-Office Bleaching Gel

2016 ◽  
Vol 41 (4) ◽  
pp. 388-396 ◽  
Author(s):  
M Rezende ◽  
L Ferri ◽  
S Kossatz ◽  
AD Loguercio ◽  
A Reis
Keyword(s):  
Hydrogen Peroxide ◽  
Repeated Measures ◽  
Color Change ◽  
Absolute Risk ◽  
Color Stability ◽  
Fisher Exact Test ◽  
High Hydrogen ◽  
Significant Difference ◽  
Shade Guide ◽  
At Home

SUMMARY Objectives: The aim of this study was to evaluate the efficacy, color stability, risk, and intensity of tooth sensitivity (TS) of combined bleaching techniques performed with 20% or 35% hydrogen peroxide for an in-office protocol. Methods: Thirty patients were randomly divided into two groups and submitted to a single 45-minute in-office bleaching session with 35% hydrogen peroxide or 20% hydrogen peroxide. At-home bleaching was performed with 10% carbamide peroxide for two hours daily over the course of two weeks. The color was evaluated with the value-oriented shade guide Vita Classical at different periods up to 12 months after bleaching. Patients recorded the intensity of TS using a five-point verbal scale. Color change data were submitted to a two-way repeated-measures analysis of variance and Tukey test (α=0.05). The absolute risk and intensity of TS were compared with the Fisher exact test and Mann-Whitney test, respectively (α=0.05). Results: On average, an effective and similar whitening of three units in shade guide was observed for both groups, which remained stable for 12 months. When both protocols were compared, the one with hydrogen peroxide 35% showed a higher risk (p=0.02) and intensity of TS (p=0.04). In regard to the TS intensity, no significant difference was observed up to 48 hours after in-office bleaching (p=0.09) and during the at-home bleaching phase of the study (p=0.71). Conclusion: The combined bleaching technique using at-home bleaching associated with in-office bleaching was effective and stable over the course of 12 months, regardless of the concentration of the hydrogen peroxide used for in-office bleaching. However, the protocol with 20% hydrogen peroxide produced lower risk and intensity of TS.

scholarly journals Shear bond strength after dentin bleaching with 10% carbamide peroxide agents

2004 ◽  
Vol 18 (2) ◽  
pp. 162-167 ◽  
Author(s):  
Roberta Tarkany Basting ◽  
Patrícia Moreira de Freitas ◽  
Luiz André Freire Pimenta ◽  
Mônica Campos Serra
Keyword(s):  
Bond Strength ◽  
Shear Bond Strength ◽  
Artificial Saliva ◽  
In Vitro Study ◽  
Adhesive System ◽  
Deionized Water ◽  
Tooth Surface ◽  
Carbamide Peroxide ◽  
Peroxide Bleaching

This in vitro study evaluated the shear bond strength (SBS) of dentin treated with two 10% carbamide peroxide bleaching agents 15 days after bleaching and storage in artificial saliva. Dentin fragments were randomly divided into 3 groups (n = 20) for the treatment with the two different bleaching agents (Rembrandt 10% or Opalescence 10%) or with a placebo agent, applied to the tooth surface for 8 hours a day. During the remaining time, the specimens were stored in artificial saliva. After 42 days, the fragments were stored in artificial saliva for 14 days. Another group (n = 20) was exposed to distilled and deionized water for 56 days. An adhesive system and microhybrid composite resin were used to prepare specimens for the SBS test. SBS tests were performed and the fractured surfaces were visually examined using a stereoscope at 30 X magnification. The analysis of variance (ANOVA) and SIDAK tests showed higher SBS values for dentin treated with Opalescence 10% than for dentin treated with Rembrandt 10% or placebo. Groups treated with Rembrandt 10%, Opalescence 10% or placebo did not differ from the group treated with distilled and deionized water. Ten percent carbamide peroxide agents or a placebo agent caused no differences in SBS of dentin after 15 days of storage in artificial saliva.

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