scholarly journals MODERN METHODS FOR ANGIOGENESIS ASSESSMENT IN CLINICAL PRACTICE

2017 ◽  
Vol 5 (1) ◽  
pp. 110-123
Author(s):  
M.O. MAVLIKEEV ◽  
◽  
A.A. TITOVA ◽  
D.O. GUDZ ◽  
R.V. DEEV ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Modern Methods

The possibility of using myotonometry to assess the muscle fatigue of physical labor workers

2020 ◽  
Vol 60 (11) ◽  
pp. 892-894
Author(s):  
Evgeniya S. Shitova ◽  
Inga S. Malakhova ◽  
Vladislav I. Lemeshko
Keyword(s):  
Clinical Practice ◽  
Occupational Health ◽  
Muscle Fatigue ◽  
Soleus Muscle ◽  
Initial Level ◽  
Maximum Load ◽  
Main Area ◽  
Modern Methods ◽  
The Moment

Introduction. The use of classical methods for diagnosing muscle fatigue of physical workers, including dynamometry and electromyography, is often limited due to the complexity of the process, the inability to use them in production, and the subjectivity of the methodology. At the same time, such a method as myotonometry does not have these disadvantages, but the main area of its use at the moment is clinical practice. The aim of study was to determine the possibility of using myotonometry to assess muscle fatigue. Materials and methods. In the course of the study, the biomechanical characteristics of muscles that differ in their depth were evaluated using the "MyotonPro" device (Myoton AS, Estonia). We determined the tone and stiffness of the biceps of the shoulder, the soleus muscle, and the muscle that straightens the back at different periods of time under the influence of maximum load on them. Results. It was found that the studied parameters of these muscles immediately after performing a series of exercises "to failure" statistically significantly increased, and after 30 minutes - again decreased, but did not reach the initial level. Conclusions. The myotonometric study showed objectivity, reliability, repeatability and proved to be one of the most promising modern methods for assessing muscle fatigue, including for solving problems in the field of occupational health.

scholarly journals MODERN METHODS OF GREAT OBSTETRICAL SYNDROMES PROGNOSTICATION (LITERATURE REVIEW)

2019 ◽  
Vol 72 (4) ◽  
pp. 704-706
Author(s):  
Natalia Y. Lemish
Keyword(s):  
Clinical Practice ◽  
Literature Review ◽  
Clinical Studies ◽  
Negative Consequences ◽  
Early Correction ◽  
Modern Methods ◽  
History Of ◽  
Laboratory Investigations

Introduction: The term “Great Obstetrical Syndromes” (GOS) was widely implemented to clinical practice after 2009, due to publications of G. C. Di Renzo and R. Romero. The effective prognostical methods are still being searched for early correction of the disorders and decrease of negative consequences on mother and fetus. The aim: To analyze the up to date data concerning prognostication of Great obstetrical syndromes. Materials and methods: Used database Pubmed from 2004 up till 2019 to search clinical studies of great obstetrical syndromes. Conclusions: The literature review summarizes the data about existing methods of prognostication of GOS based on history of the patient and the results of additional clinical and laboratory investigations.

Modern methods of assessing function and strength ofpelvic muscles in women

2019 ◽  
Vol 1 (1) ◽  
pp. 80-85
Author(s):  
G. B. Dikke ◽  
Yu. G. Kucheryavaya ◽  
A. A. Sukhanov ◽  
I. I. Kukarskaya ◽  
E. Yu. Scherbatykh
Keyword(s):  
Clinical Practice ◽  
Pelvic Floor ◽  
Age Groups ◽  
Visual Observation ◽  
Pelvic Floor Muscles ◽  
Free Access ◽  
Magnetic Resonance Imaging Measure ◽  
Modern Methods ◽  
Pelvic Floor Insufficiency ◽  
The Right

Objective: to provide an overview of modern methods for assessing the function and strength of the pelvic floor muscles in women available for clinical practice. The main provisions. Foreign and domestic sources found in free access Internet databases were analyzed. Visual observation, palpation, perineometry, electromyography, ultrasound and magnetic resonance imaging measure various aspects of the function and strength of the pelvic floor muscles. Perineometry allows you to accurately measure the force of contractions of the pelvic floor muscles and is an easy and affordable way. Oxford vaginal palpation technologies, biofeedback devices, and ultrasound can be important clinical tools in the practice of a physician to quantify dysfunction of the pelvic floor. Conclusion. The obtained data on methods for assessing the function and strength of the pelvic floor muscles indicate the need for perineometry in clinical practice for the timely diagnosis of pelvic floor insufficiency, which will allow choosing the right rehabilitation method for women of different age groups.

scholarly journals Cariprazine is a modern antipsychotic with a favorable neuroendocrine profile

2020 ◽  
Vol 2 (3) ◽  
pp. 58-63
Author(s):  
Igor V. Dorovskikh ◽  
Tatyana A. Pavlova ◽  
Julia M. Scheidegger
Keyword(s):  
Clinical Practice ◽  
Mental Disorders ◽  
Medical History ◽  
Dopamine Receptors ◽  
Clinical Studies ◽  
High Frequency ◽  
Clinical Symptoms ◽  
Partial Agonist ◽  
Correct Choice ◽  
Modern Methods

This article provides an overview of the causes and mechanisms of drug hyperprolactinemia (GP) associated with the use of antipsychotics, and describes its main clinical symptoms. The most probable factors of the high frequency of GP development that persists to date when using antipsychotics in the practice of a psychiatrist are considered. Modern methods of its prevention and correction developed by domestic and foreign researchers are presented. Emphasis is placed on the importance and necessity of careful collection of the patient's medical history, laboratory and instrumental examination, monitoring of the dynamics of hormonal indicators, correct choice of therapeutic tactics for the prevention of GP and its timely relief. The neuroendocrine profile of the latest generation of antipsychotics is considered. Special attention is paid to the partial agonist of D-2, D3-dopamine receptors cariprazine. Based on the review of recent clinical studies, the possibilities of its use in clinical practice are considered in detail, and the neuroendocrine profile of the drug is presented. The prospects of its use as a corrector of GP associated with the treatment of mental disorders with other antipsychotics are evaluated.

scholarly journals On modern methods of automated diagnosis of skin tumors in clinical practice

2020 ◽  
pp. 76-78
Author(s):  
V. Yu. Sergeev ◽  
Yu. Yu. Sergeev ◽  
O. B. Tamrazova ◽  
V. G. Nikitaev ◽  
A. N. Pronichev
Keyword(s):  
Public Health ◽  
Artificial Intelligence ◽  
Clinical Practice ◽  
Public Health Service ◽  
Automated Diagnosis ◽  
Skin Cancers ◽  
Modern Methods ◽  
Number Of Publications ◽  
New Algorithms ◽  
Artificial Intelligence Systems

Despite the existence of many algorithms for automated diagnosis of melanoma and other skin cancers, these remain almost inaccessible to public health service. A small number of publications on the efficacy of existing artificial intelligence systems marks the problems of their implementation into current examination routines in dermatology and oncology. New algorithms and software solutions as well as studies demonstrating their diagnostic accuracy on compatible and verifiable clinical material are still in demand.

Laser technology

2019 ◽  
Author(s):  
Yuliya Mandra ◽  
Khiyir Abdulkerimov ◽  
Elena Svetlakova ◽  
Sergey Griroriev ◽  
N. Gegalina ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Clinical Data ◽  
Diagnosis And Treatment ◽  
Laser Technology ◽  
World Scientific ◽  
Modern Methods ◽  
Experimental Laboratory ◽  
Laser Dentistry ◽  
Clinical Cases

The manual is intended for students of the Faculty of Dentistry, residents, practicing dentists of various specialties. Dedicated to current issues of laser dentistry. Developed taking into account world scientific and clinical practice, experimental, laboratory and clinical data obtained by the authors. This manual presents materials relating to modern ideas about the use of laser technology in dentistry, highlights modern methods of diagnosis and treatment, clinical cases are given.

scholarly journals Modern Methods of Devic’s Disease Treatment

2020 ◽  
Vol 8 (B) ◽  
pp. 1083-1087
Author(s):  
Grigolashvili Marina Archilovna ◽  
Kim Ekaterina Danilovna ◽  
Beisembayeva Mira Baikonyrovna ◽  
Smagulov Amirzhan Muratovich ◽  
Omarova Sholpan Kabidenovna ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Clinical Practice ◽  
Successful Implementation ◽  
Disease Treatment ◽  
Devic’S Disease ◽  
Treatment And Prevention ◽  
Number Of Patients ◽  
Modern Methods ◽  
Devic's Disease ◽  
Methods Of Treatment

BACKGROUND: Neuromyelitis optica (NMO) (also known as opticomyelitis, Devic’s syndrome/disease) is an idiopathic inflammatory disorder of the central nervous system characterized by predominant involvement of the optic nerves, spinal cord, and extensive transverse myelitis. To date, there are no convincing clinical trials that would fully evaluate the efficacy and safety of drugs for the treatment and prevention of NMO exacerbation. Taking into account the malignant course that quickly leads to disability of young, economically active population, the issues of searching for effective methods of NMO treatment remain highly urgent. AIM: The purpose of the study was to examine available modern methods of treatment and prevention of NMO exacerbation, which have potential and require further detailed clinical trials to ensure possible application of these treatment options in clinical practice. MATERIALS AND METHODS: We have reviewed previously applied and modern methods of treatment. We have analyzed systematic reviews, clinical, randomized, and retrospective studies of scientific medical databases: PubMed, Cochrane, The Lancet, UpToDate, and reviews of world medical journals in Russian and English. CONCLUSIONS: The authors concluded that there is a sufficient number of drugs and combinations of methods of Devic’s disease treatment. We were interested in combinations of rituximab (RIT) and autologous stem cell transplantation, RIT and fetal hepatocyte transplantation, and RIT and strengthening the effect by plasmapheresis sessions. However, successful implementation of these methods in clinical practice requires conducting controlled clinical trials with a larger number of patients and longer follow-up periods.

The miR-21 potential of serving as a biomarker for liver diseases in clinical practice

2020 ◽  
Vol 48 (5) ◽  
pp. 2295-2305
Author(s):  
Jiawei Zhang ◽  
Dandan Li ◽  
Rui Zhang ◽  
Peng Gao ◽  
Rongxue Peng ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Liver Diseases ◽  
Hepatic Disease ◽  
Noninvasive Detection ◽  
Diagnosis And Prognosis ◽  
Expected Performance ◽  
Potential Biomarker ◽  
Disease Condition ◽  
Complex Regulatory Network

The role of miR-21 in the pathogenesis of various liver diseases, together with the possibility of detecting microRNA in the circulation, makes miR-21 a potential biomarker for noninvasive detection. In this review, we summarize the potential utility of extracellular miR-21 in the clinical management of hepatic disease patients and compared it with the current clinical practice. MiR-21 shows screening and prognostic value for liver cancer. In liver cirrhosis, miR-21 may serve as a biomarker for the differentiating diagnosis and prognosis. MiR-21 is also a potential biomarker for the severity of hepatitis. We elucidate the disease condition under which miR-21 testing can reach the expected performance. Though miR-21 is a key regulator of liver diseases, microRNAs coordinate with each other in the complex regulatory network. As a result, the performance of miR-21 is better when combined with other microRNAs or classical biomarkers under certain clinical circumstances.

Meeting the Best Practice for Hearing Aid Verification in Children: Challenges and Future Directions

2019 ◽  
Vol 28 (4) ◽  
pp. 877-894
Author(s):  
Nur Azyani Amri ◽  
Tian Kar Quar ◽  
Foong Yen Chong
Keyword(s):  
Clinical Practice ◽  
Hearing Aids ◽  
Best Practice ◽  
Hearing Aid ◽  
Evidence Based ◽  
Future Directions ◽  
Major Barrier ◽  
Klang Valley ◽  
Age Range ◽  
Fitting Hearing Aids

Purpose This study examined the current pediatric amplification practice with an emphasis on hearing aid verification using probe microphone measurement (PMM), among audiologists in Klang Valley, Malaysia. Frequency of practice, access to PMM system, practiced protocols, barriers, and perception toward the benefits of PMM were identified through a survey. Method A questionnaire was distributed to and filled in by the audiologists who provided pediatric amplification service in Klang Valley, Malaysia. One hundred eight ( N = 108) audiologists, composed of 90.3% women and 9.7% men (age range: 23–48 years), participated in the survey. Results PMM was not a clinical routine practiced by a majority of the audiologists, despite its recognition as the best clinical practice that should be incorporated into protocols for fitting hearing aids in children. Variations in practice existed warranting further steps to improve the current practice for children with hearing impairment. The lack of access to PMM equipment was 1 major barrier for the audiologists to practice real-ear verification. Practitioners' characteristics such as time constraints, low confidence, and knowledge levels were also identified as barriers that impede the uptake of the evidence-based practice. Conclusions The implementation of PMM in clinical practice remains a challenge to the audiology profession. A knowledge-transfer approach that takes into consideration the barriers and involves effective collaboration or engagement between the knowledge providers and potential stakeholders is required to promote the clinical application of evidence-based best practice.

Hybrid Telecoaching for Corporate Speech Training and Potential Applications to Clinical Practice

2019 ◽  
Vol 4 (2) ◽  
pp. 322-324
Author(s):  
Thomas F. Burke
Keyword(s):  
Clinical Practice ◽  
Engineering Teams ◽  
Corporate Strategies ◽  
Corporate Speech ◽  
Phone Calls ◽  
Future Clinical Practice ◽  
Fortune 100 ◽  
Potential Applications ◽  
Language Pathology ◽  
Development Engineering

Purpose The purpose of this article was to describe a model for “hybrid speech telecoaching” developed for a Fortune 100 organization and offer a “thought starter” on how clinicians might think of applying these corporate strategies within future clinical practice. Conclusion The author contends in this article that corporate telecommunications and best practices gleaned from software development engineering teams can lend credibility to e-mail, messaging apps, phone calls, or other emerging technology as viable means of hybrid telepractice delivery models and offer ideas about the future of more scalable speech-language pathology services.

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