Addressing The Evidence Gap in Medication for Pregnant Women: The Need for More Solidarity?

2021 ◽  
Vol 66 (Special Issue) ◽  
pp. 90-90
Author(s):  
Marieke Hollestelle ◽  
◽  
Rieke van der Graaf ◽  
Miriam Sturkenboom ◽  
Hans van Delden ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Rare Disease ◽  
Potential Role ◽  
Evidence Base ◽  
Status Quo ◽  
Active Involvement ◽  
Shared Experiences ◽  
Depth Analysis ◽  
The Status

"Although the inclusion of pregnant women in clinical research has been widely promoted over the last decade, there is still a lack of evidence-based knowledge concerning risk and efficacy of medications used for obstetric and non-obstetric illnesses. It has been argued that solidarity is of key importance in changing the status quo for the group of rare disease patients, for whom, just like pregnant women, a poor evidence-base exists regarding treatments. Therefore, we explore the potential role of solidarity in changing the status quo in the field of pregnant women. By way of an in-depth analysis of the concept of solidarity developed by Barbara Prainsack and Alena Buyx, we assess the role of solidarity in the group of rare disease patients and apply the conditions for solidarity to the group of pregnant women. From this analysis, we derive three lessons for the group of pregnant women: 1) being able to self-organize can have a significant effect on the ability to demand change, 2) organizing and action can be triggered by commonalities, such as shared experiences 3) enabling change involves enacted commitments to accept a cost to assist others with whom one recognizes a similarity in a relevant respect. In this presentation, we argue that an active involvement of pregnant women described as an act of solidarity should be stimulated. With that, engagement and solidarity from other stakeholders involved are necessary to raise awareness about the shared experiences of pregnant women and to realize the infrastructure for active involvement. "

scholarly journals Gut microbiota influence in type 2 diabetes mellitus (T2DM)

Gut Pathogens ◽  
2021 ◽  
Vol 13 (1) ◽  
Author(s):  
A. L. Cunningham ◽  
J. W. Stephens ◽  
D. A. Harris
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Gut Microbiota ◽  
Potential Role ◽  
Evidence Base ◽  
Human Metabolism ◽  
Altered Glucose

AbstractA strong and expanding evidence base supports the influence of gut microbiota in human metabolism. Altered glucose homeostasis is associated with altered gut microbiota, and is clearly associated with the development of type 2 diabetes mellitus (T2DM) and associated complications. Understanding the causal association between gut microbiota and metabolic risk has the potential role of identifying susceptible individuals to allow early targeted intervention.

Speciation and changes in male gene expression in Drosophila

Genome ◽  
2020 ◽  
pp. 1-11
Author(s):  
Bahar Patlar ◽  
Alberto Civetta
Keyword(s):  
Gene Expression ◽  
Reproductive Isolation ◽  
Potential Role ◽  
Regulation Of Gene Expression ◽  
Drosophila Model ◽  
Depth Analysis ◽  
The Impact ◽  
Plastic Responses ◽  
Male Gene

It has long been acknowledged that changes in the regulation of gene expression may account for major organismal differences. However, we still do not fully understand how changes in gene expression evolve and how do such changes influence organisms’ differences. We are even less aware of the impact such changes might have in restricting gene flow between species. Here, we focus on studies of gene expression and speciation in the Drosophila model. We review studies that have identified gene interactions in post-mating reproductive isolation and speciation, particularly those that modulate male gene expression. We also address studies that have experimentally manipulated changes in gene expression to test their effect in post-mating reproductive isolation. We highlight the need for a more in-depth analysis of the role of selection causing disrupted gene expression of such candidate genes in sterile/inviable hybrids. Moreover, we discuss the relevance to incorporate more routinely assays that simultaneously evaluate the potential effects of environmental factors and genetic background in modulating plastic responses in male genes and their potential role in speciation.

scholarly journals Gestation, equality and freedom: ectogenesis as a political perspective

2019 ◽  
Vol 46 (2) ◽  
pp. 76-82 ◽  
Author(s):  
Giulia Cavaliere
Keyword(s):  
Status Quo ◽  
Positive Case ◽  
The Political ◽  
Small Subset ◽  
Human Fetuses ◽  
Political Perspective ◽  
Women's Equality ◽  
The Status ◽  
Limited Scope

The benefits of full ectogenesis, that is, the gestation of human fetuses outside the maternal womb, for women ground many contemporary authors’ arguments on the ethical desirability of this practice. In this paper, I present and assess two sets of arguments advanced in favour of ectogenesis: arguments stressing ectogenesis’ equality-promoting potential and arguments stressing its freedom-promoting potential. I argue that although successfully grounding a positive case for ectogenesis, these arguments have limitations in terms of their reach and scope. Concerning their limited reach, I contend that ectogenesis will likely benefit a small subset of women and, arguably, not the group who most need to achieve equality and freedom. Concerning their limited scope, I contend that these defences do not pay sufficient attention to the context in which ectogenesis would be developed and that, as a result, they risk leaving the status quo unchanged. After providing examples of these limitations, I move to my proposal concerning the role of ectogenesis in promoting women’s equality and freedom. This proposal builds on Silvia Federici’s, Mariarosa Dalla Costa’s and Selma James’ readings of the international feminist campaign ‘Wages for Housework’. It maintains that the political perspective and provocation that ectogenesis can advance should be considered and defended.

scholarly journals Prawo małoletnich do wolności od hazardu, uzależnienia od Internetu i gier komputerowych

2020 ◽  
Vol 6 ◽  
pp. 47-75
Author(s):  
Wioletta Pawska
Keyword(s):  
Sense Of Belonging ◽  
Status Quo ◽  
The Internet ◽  
Gaming Addiction ◽  
Online Environment ◽  
Parents And Children ◽  
The Status ◽  
Legislative Changes ◽  
The Right

The Right of Minors to Freedom from Gambling and Internet andGaming Addition The aim of the article is to highlight the dangers of gambling and Internet and gaming addiction of minors and young persons. The author is convinced that in the absence of positive legislative changes and if creators of games engaging young persons in gaming are not punished, children will not be safe in the online environment. There will not have any other lives than those in the games they play. Additionally, the most important thing is the role of the parents, guardians and teachers. They should talk to children about the problem, show them the dangers and organise better their free time – in an educational and carefree way. In accordance with the obligatory rules of custody, they should ensure them suitable development, safety and a sense of belonging. The teachers ought to support these activities. Summarising, if the status quo continues to be tolerated, minors and young person’s will be deprived of carefree life and suffer from harm and even sudden deaths. The author is sure that parents and children do not give enough attention to that and we should not take away from young person’s the joy of simple things letting them play in the Internet instead.

The Neglected Role of the Status Quo in Models of Issue Voting

1985 ◽  
Vol 47 (1) ◽  
pp. 230-237 ◽  
Author(s):  
Bernard Grofman
Keyword(s):  
Status Quo ◽  
Issue Voting ◽  
The Status

Theatricalizing the National Housing Crisis in Mike Bartlett’s Game and Philip Ridley’s Radiant Vermin

2018 ◽  
Vol 6 (1) ◽  
pp. 55-68
Author(s):  
William C. Boles
Keyword(s):  
Great Britain ◽  
Great Recession ◽  
Status Quo ◽  
Housing Crisis ◽  
National Crisis ◽  
The Great Recession ◽  
The Status ◽  
Verbatim Theatre ◽  
Great Game

AbstractSince the start of the new millennia, the words ‘national crisis’ have not been far removed from many of the plays on the British stage. The aftermath of 9/11 and the British government’s decision to aid George Bush’s Middle East invasion plans sparked plays by David Hare, Roy Williams, and the Tricycle Theatre’s The Great Game as well as verbatim theatre pieces. The Great Recession unleashed works by David Hare (again), Laura Wade, and Lucy Prebble, among others. The increasing threats of floods across Great Britain and Europe placed the crisis of climate change front and centre in plays by Mike Bartlett and Steve Waters. The housing crisis, while not as provocative a theatrical topic as the ones above, has also inspired theatrical responses, including Mike Bartlett’s Game and Philip Ridley’s Radiant Vermin, and these two works are the focus of my paper. More specifically, I will examine each playwright’s focus on the role of the homeless in regards to the housing crisis. Interestingly, both playwrights posit that the victimization of the homeless is the crucial solution to not only solving the housing crisis in Britain, but also maintaining the status quo of Britain’s affluent population.

scholarly journals From Self-Attaching to Self-Emptying: An Investigation of Xuanzang’s Account of Self-Consciousness

Open Theology ◽  
2017 ◽  
Vol 3 (1) ◽  
Author(s):  
Jingjing Li
Keyword(s):  
Transcendental Phenomenology ◽  
Transcendental Idealism ◽  
Status Quo ◽  
Religious Rituals ◽  
The Status ◽  
Science Of Mind ◽  
Descriptive Level

AbstractIn this paper, I investigate the account of self-consciousness provided by Chinese Yogācārins Xuanzang (602-664CE) and Kuiji (632-682CE). I will explain how they clarify the transition from selfattaching to self-emptying through the articulation of consciousness (vijñāna). Current scholarship often interprets the Yogācāra account of consciousness either as a science of mind or as a metaphysical idealism. Both interpretations are misleading, partly because they perpetuate various stereotypes about Buddhism, partly also because they overlook the religious goal of realizing in practice the wisdom of emptiness and the non-egoistic compassion. Against the status quo, I argue that through their account of self-consciousness, Xuanzang and Kuiji advocate what can be referred to as transcendental idealism that stresses the correlation between subjectivity and objectivity. Yogācārins thus neither nullify the existence of subjectivity nor formulate subjectivity as a higher entity. The transcendental idealism yields a Buddhist phenomenology that is similar to and also different from Edmund Husserl’s transcendental phenomenology. In what follows I will first characterize Husserl’s phenomenology as an approach to consciousness at two levels (the descriptive level and the explicative level). Then, I elicit the Buddhist phenomenology from Yogācāra philosophy that is not only descriptive and explicative but also prescriptive. This three-level architectonic of consciousness, while reaffirming the importance of agency, further justifies the role of religious rituals and moral practices for Yogācāra devotees.

7 Role of National Courts during the Proceedings

2015 ◽  
Author(s):  
Blackaby Nigel ◽  
Partasides Constantine ◽  
Redfern Alan ◽  
Hunter Martin
Keyword(s):  
National Court ◽  
Status Quo ◽  
Arbitral Tribunal ◽  
Judicial Control ◽  
National Courts ◽  
The Status ◽  
Model Law ◽  
Interim Measures

This chapter examines the role that national courts play at the beginning, during, and end of arbitration proceedings. Arbitration is dependent on the support of the courts, which alone have the power to intercede when one party seeks to sabotage proceedings. This intervention may be possible at the beginning of the arbitral process in the context of the enforcement of the arbitration agreement, the establishment of the tribunal, and challenges to jurisdiction. National courts may also intervene during proceedings: it may be necessary for the arbitral tribunal or a national court to issue orders intended to preserve evidence, to protect assets, or in some other way to maintain the status quo pending the outcome of the arbitration. Under the UNCITRAL Rules and Model Law, such orders are called ‘interim measures’. The chapter also describes how national courts exercise judicial control over the resulting award.

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