scholarly journals Correlation between Stigma and Adherence to ART among HIV-Positive Adolescents: A Cross-Sectional Study

2021 ◽  
Vol 08 (01) ◽  
pp. 1-7
Author(s):  
Shaily B Surti ◽  

Despite the prominence of youth on the global agenda, young people are often left behind in national HIV responses. UNAIDS estimates indicate that AIDS-related deaths among young people are increasing. One of the reasons for this is poor prioritization of adolescents in national plans for scale-up of HIV testing, treatment and counseling services. The objectives of the current study was to: (1) To understand the social issues such as stigma and disclosure faced by them (2) To document the adherence to ART among them and study the effect of stigma on it. The cross-sectional study was conducted at HIV clinic, at ART Centre, Surat (Tertiary Care Level Institute) among adolescents between age-group 13-19 years during December-2015 to February-2016. By purposive sampling following desk review of Hospital data, 105 participants were enrolled. Frequency distribution, Factor analysis and Correlation were utilized for analysis. Around 80% feared that they will lose their friends if they came to know about their serostatus. Factor analysis yielded 2 factors- Blaming and Distancing. These two factor scores were found significantly correlated to adherence to ART. Only 7% chose to share about the status with friends outside the family. The study findings suggest that there is a need for prioritizing adolescent health among seropositives as their difficulties are different than children and adults in handling social issues like stigma due to their age and peer pressure. The lack of knowledge and fear of stigma among them if not addressed may lead to poor adherence to treatment and therefore, clinical complications.

Vacunas ◽  
2020 ◽  
Vol 21 (2) ◽  
pp. 95-104 ◽  
Author(s):  
Y.M. AlGoraini ◽  
N.N. AlDujayn ◽  
M.A. AlRasheed ◽  
Y.E. Bashawri ◽  
S.S. Alsubaie ◽  
...  

Author(s):  
Nandini Chatterjee ◽  
Supratick Chakraborty ◽  
Mainak Mukhopadhyay ◽  
Sinjon Ghosh ◽  
Bikramjit Barkandaj ◽  
...  

2020 ◽  
Vol 32 (1) ◽  
Author(s):  
Nearmeen M. Rashad ◽  
Marwa G. Amer ◽  
Waleed M. Reda Ashour ◽  
Hassan M. Hassanin

Abstract Background Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system with varied clinical features. Disease-modifying drugs (DMDs) of MS associated with different types of thyroiditis. In this cross-sectional study, we aimed to assess the prevalence of thyroid dysfunction in MS and to investigate the association between DMDs and the risk of thyroiditis in MS. A cross-sectional study included 100 patients with relapsing-remitting multiple sclerosis (RRMS) in relapse, and the diagnosed was according to revised McDonald’s criteria 2010. Results Our results revealed that the prevalence of thyroiditis was 40%; autoimmune (34%) and infective (6%) among patients with RRMS in relapse and cerebellar symptoms were significantly higher in patients with thyroiditis compared to patients without thyroiditis. Regarding the association between DMDs and thyroiditis, the prevalence of patients treated with interferon-beta-1b was higher in MS patients with thyroiditis compared to MS patients without thyroiditis. However, the prevalence of patients treated with interferon-beta-1a was lower in MS patients with thyroiditis compared to MS patients without thyroiditis. In addition, we found CMV infection was more common in patients treated by interferon beta-1b and candida infection was common in patients treated by fingolimod. Conclusions Thyroiditis is commonly observed in patients with RRMS in relapse and higher prevalence of patients treated with interferon-beta-1b which is commonly associated with thyroiditis and CMV infection; however, candida thyroid infection was common in MS patients treated by fingolimod.


BMJ Open ◽  
2020 ◽  
Vol 10 (11) ◽  
pp. e037282
Author(s):  
Rieko Mutai ◽  
Yoshifumi Sugiyama ◽  
Shuhei Yoshida ◽  
Ryoko Horiguchi ◽  
Takamasa Watanabe ◽  
...  

ObjectivesThe primary objective of this study was to develop the Japanese version of the Patient Centred Assessment Method (PCAM) and its user guide. The secondary objective was to examine the validity and reliability in the primary care setting.DesignCross-sectional study.SettingThree family physician teaching clinics located in urban residential areas in Tokyo, Japan.ParticipantsPatients who were aged 20 years or older, and who had an appointment with physicians at the three participating clinics.Main outcome measuresPatient complexity measured by PCAM and complexity/burden level measured by a Visual Analogue Scale (VAS).ResultsAlthough confirmatory factor analysis using a model described in a previous study revealed that the indices did not meet the criteria for good fit, exploratory factor analysis revealed a new three-factor structure of ‘Personal well-being,’ ‘Social interaction’ and ‘Needs for care/service.’ Cronbach’s alpha of PCAM was 0.86. Spearman’s rank correlation coefficients between PCAM scores and VAS scores were 0.51 for complexity (p<0.001) and 0.41 for burden (p<0.001). There were 42 patients (14.3% of total patients) with PCAM scores greater than its mean of 16.5 but with complexity VAS scores less than its mean of 20.8.ConclusionsThe Japanese version of PCAM and its user guide were developed through Japanese translation and cultural adaptation by cognitive debriefing. PCAM is a valid and reliable tool to assess patient complexity in the primary care settings in Japan. Additionally, although the correlation between total PCAM scores and complexity/burden as assessed by VAS was moderate, PCAM can more precisely identify patient complexity than skilled physician’s intuition.


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