Voluntary Control of Breathing Pattern in Asthmatic Children

1996 ◽  
Vol 83 (3_suppl) ◽  
pp. 1384-1386 ◽  
Author(s):  
Nathalie Blanc-Gras ◽  
Gila Benchetrit ◽  
Jorge Gallego
Keyword(s):  
Visual Feedback ◽  
Breathing Pattern ◽  
Respiratory Muscles ◽  
Control Of Breathing ◽  
Voluntary Control ◽  
Healthy Children ◽  
Target Pattern ◽  
Video Screen ◽  
Asthmatic Children

15 asthmatic children and 15 healthy children were trained to adjust their breathing pattern to a target pattern displayed on a video screen by using visual feedback. The error scores in the two groups were not significantly different. These data did not support the hypothesis that voluntary control of respiratory muscles is impaired in asthmatics.

scholarly journals Correlation between vitamin D serum level and total IgE in asthmatic children

2020 ◽  
Vol 12 (2) ◽  
pp. 37-45
Author(s):  
Vesna Micevska ◽  
Tatjana Jakovska Mareti ◽  
Ilija Kirovski ◽  
Olivera Jordanova
Keyword(s):  
Vitamin D ◽  
Serum Level ◽  
P Value ◽  
Healthy Children ◽  
Total Ige ◽  
Asthmatic Children ◽  
Significant Difference ◽  
Children With Asthma ◽  
The Mean ◽  
Chronical Disease

Asthma is a chronical disease of the airways characterized by reversible obstruction of the bronchi and airway inflammation. In recent decades, the scientific interest of the vitamin D system and its role in development of asthma and other alergic diseases has been increased. Aims of this study are to mesure and compare the serum level of 25 OHD in asthmatic and healthy children and corelate the level of 25OHD and total IgE in asthmatic children. This prospective study includes 70 children at age 2 to 14, of which 32 are children with diagnosed asthma and 38 healthy children. In both  of the groups the serum level of 25 OHD was measured  and by the results 18 % of the healthy children (C) and 28% of the asthma children (E) had 25OHD  deficiency, 45%  of C and 50% of E were insufficient and 37 % of C / 22% of E were with normal 25 OHD serum level. The mean level of 25OHD in C was 27,83 +/- 10,24 and in E 20,9 ng/ml +/- 10,72. The mean levels in both groups had statistic significant difference with p-value < 0,05. According to age no statistic significant difference was found in both of the groups. There was a statisticaly significant decreased serum level of 25 OHD in asthmatic females.In the examined group (children with asthma) there was a negative linear correlation (association) of the level of 25OHD and total IgE serum level with r=- 0,55  Vitamin D serum level measurements in asthma patients gives the possibility for discovering the connection between its deficiency and development of asthma symptoms.

scholarly journals Relationship of Oxidant and Antioxidant Markers to Asthma Severity in Egyptian Asthmatic Children

2017 ◽  
Vol 5 (5) ◽  
pp. 645-650 ◽  
Author(s):  
Inas R. EL-Alameey ◽  
Gihan A. Fathy ◽  
Mones M. Abu Shady ◽  
Alaa Ali ◽  
Hanan A. Fathy ◽  
...  
Keyword(s):  
Asymmetric Dimethylarginine ◽  
Strong Predictor ◽  
Predictive Biomarker ◽  
Asthma Severity ◽  
Healthy Children ◽  
Serum Concentrations ◽  
Asthmatic Children ◽  
Paraoxonase Activity ◽  
Asthmatic Patients ◽  
Anti Oxidant

BACKGROUND: Asthma is a chronic airway disease which is characterized by oxidant antioxidant imbalance with the generation of oxidative stress related mediators.AIM: The study aimed to evaluate the role of asymmetric dimethylarginine, and malondialdehyde as oxidant markers and serum paraoxonase activity as an antioxidant marker in asthma, and to determine their relationship to the asthma severity and lung function among asthmatic children in Egypt.PATIENTS AND METHODS: This case control study was conducted on sixty patients with asthma compared with sixty apparently healthy children of matched age and sex.RESULTS: Serum concentrations of oxidant markers as asymmetric dimethylarginine and malondialdehyde were significantly increased in asthmatic patients while anti-oxidant marker as paraoxonase activity was significantly decreased compared to healthy controls (P < 0.05). ANOVA test revealed highly significant elevation of the serum concentrations of oxidant markers while anti-oxidant marker was significantly decreased in severe asthmatic patients (P < 0.001) compared to the patients with moderate and mild asthma respectively. Serum malondialdehyde concentration was a strong predictor of asthma severity by multiple regression analysis (P < 0.05).CONCLUSION: The study revealed an imbalance between oxidative and antioxidant defence systems in asthmatic children. Serum concentration of malondialdehyde was the most predictive biomarker having a significant association with asthma severity.

scholarly journals THE IMPACT OF ASTHMAAND ITS MEDICATIONS ON DENTAL CARIES STATUS AND STREPTOCOCCUS MUTANS COUNT IN CHILDREN: A CROSS-SECTIONAL STUDY

2020 ◽  
pp. 20-23
Author(s):  
Sneha Upadhyay ◽  
Jyoti Bhavthankar ◽  
Mandakini Mandale ◽  
Nivedita Kaorey
Keyword(s):  
Dental Caries ◽  
Streptococcus Mutans ◽  
Cross Sectional Study ◽  
Control Group ◽  
Healthy Children ◽  
Sectional Study ◽  
Cross Sectional ◽  
Asthmatic Children ◽  
Significant Difference ◽  
The Impact

Background: Asthma and its medications have been linked to oral diseases in asthmatic children. Aim: Assessment of the dental caries status, salivary Streptococcus mutans count and S. mutans colony score in children receiving inhaled anti asthmatic medications and their comparison in healthy children Material and Method: A cross-sectional study was performed on 40 asthmatic children and 40 healthy children in the age group of 6-14 years. DMFT/deft indices were calculated and saliva samples were collected. Diluted saliva was inoculated on MSB agar plates. S. mutans count and colony score were analysed after 24-48 hours of inoculation. Results: Statistically significant difference was observed in the mean DMFT/deft index, salivary S. mutans load and S. mutans colony score in children of the asthmatic group and control group. Conclusion: Prevalence of dental caries and cariogenic bacteria is higher in asthmatic children.

Arterial Oxygen Desaturation during Sleep in Children with Asthma and Its Relation to Airway Obstruction and Ventilatory Drive

PEDIATRICS ◽  
1980 ◽  
Vol 66 (5) ◽  
pp. 746-751
Author(s):  
Thomas F. Smith ◽  
David W. Hudgel
Keyword(s):  
Arterial Oxygen Saturation ◽  
Airflow Obstruction ◽  
Airflow Limitation ◽  
Arterial Oxygen ◽  
Healthy Children ◽  
Medication Regimen ◽  
Asthmatic Children ◽  
Control Subjects ◽  
Ventilatory Drive ◽  
Maximum Decrease

The possibility that arterial oxygen saturation (Sao2) decreases during sleep in children with chronic bronchial asthma was investigated. The relationship between decreases in sleep Sao2 and airflow obstruction and ventilatory drives, as characterized by ventilatory and inspiratory muscle activity responses to hypoxia and hypercapnia was also examined. Sixteen asthmatics on suboptimal bronchodilator therapy and ten healthy children were studied. Both maximum decrease in Sao2 and number of desaturations (decrease in Sao2 ≥4%) per hour during sleep were greater in the asthmatics than in the control subjects. Both maximum decrease in Sao2 and number of desaturations per hour asleep were correlated with change in FEV1 and FEF25%-75% over the sleep period. Changes in Sao2 were not related to awake measurements of ventilatory drive. Eight of the asthmatics also were studied when on a more optimal medication regimen. On this program they had less airflow obstruction before and after sleep, and the number and extent of decreases in Sao2 were not different from those of the control subjects. We conclude: (1) decreases in Sao2 occurred during sleep in suboptimally treated asthmatic children; (2) Sao2 changes during sleep were related to the amount of airflow obstruction that developed during sleep; (3) Sao2 changes during sleep were not related to ventilatory drive measured during wakefulness; and (4) a good therapeutic regimen eliminated abnormal amounts of sleep hypoxemia by inproving airflow limitation. However, as the results of this study indicate, when their pulmonary status is unstable, asthmatic children may develop clinically significant hypoxemia during sleep.

An assessment of nasal functions in control of breathing

1988 ◽  
Vol 65 (4) ◽  
pp. 1520-1524 ◽  
Author(s):  
Y. Tanaka ◽  
T. Morikawa ◽  
Y. Honda
Keyword(s):  
Steady State ◽  
Dead Space ◽  
Airway Resistance ◽  
Breathing Pattern ◽  
Ventilatory Response ◽  
Control Of Breathing ◽  
Mouth Breathing ◽  
Occlusion Pressure ◽  
Ventilatory Responses ◽  
End Tidal

Breathing pattern and steady-state CO2 ventilatory response during mouth breathing were compared with those during nose breathing in nine healthy adults. In addition, the effect of warming and humidification of the inspired air on the ventilatory response was observed during breathing through a mouthpiece. We found the following. 1) Dead space and airway resistance were significantly greater during nose than during mouth breathing. 2) The slope of CO2 ventilatory responses did not differ appreciably during the two types of breathing, but CO2 occlusion pressure response was significantly enhanced during nose breathing. 3) Inhalation of warm and humid air through a mouthpiece significantly depressed CO2 ventilation and occlusion pressure responses. These results fit our observation that end-tidal PCO2 was significantly higher during nose than during mouth breathing. It is suggested that a loss of nasal functions, such as during nasal obstruction, may result in lowering of CO2, fostering apneic spells during sleep.

Effect of practice on the voluntary control of a learned breathing pattern

1991 ◽  
Vol 49 (2) ◽  
pp. 315-319 ◽  
Author(s):  
Jorge Gallego ◽  
Pierre Perruchet
Keyword(s):  
Breathing Pattern ◽  
Voluntary Control

Mothers of Children with Asthma: Perceptions of Parenting Stress and the Mother-Child Relationship

1992 ◽  
Vol 71 (3_suppl) ◽  
pp. 1139-1148 ◽  
Author(s):  
David K. Carson ◽  
Roger W. Schauer
Keyword(s):  
Parenting Stress ◽  
Comparison Group ◽  
Healthy Children ◽  
Perceived Parenting ◽  
Asthmatic Children ◽  
Child Relationship ◽  
Behavioral Difficulty ◽  
Children With Asthma ◽  
Mother Child Relationship

In a study of 41 mothers of asthmatic children ranging from 8 to 13 years of age, perceived parenting stress was greater and the quality of the mother-child relationship more problematic than for a comparison group of mothers with healthy children. These mothers also perceived certain areas of behavioral difficulty in their asthmatic children that were greater than those of children in a comparative sample of mothers. The findings suggested that mothers and their asthmatic children may be at risk for a variety of individual and relational problems.

scholarly journals WEARCON: Wearable home monitoring in children with asthma reveals a strong association with hospital based assessment of asthma control.

2020 ◽  
Author(s):  
Mattienne R van der Kamp ◽  
Emilie C Klaver ◽  
Bernard J Thio ◽  
Jean MM Driessen ◽  
Franciscus HC de Jongh ◽  
...  
Keyword(s):  
Respiratory Rate ◽  
Asthma Control ◽  
Strong Association ◽  
Multiple Logistic Regression Analysis ◽  
Home Monitoring ◽  
Physiological Parameters ◽  
Respiratory Physiology ◽  
Healthy Children ◽  
Home Setting ◽  
Asthmatic Children

Abstract Asthma is one of the most common chronic diseases in childhood. Regular follow-up of physiological parameters in the home setting, in relation to asthma symptoms, can provide complementary quantitative insights into the dynamics of the asthma status. Despite considerable interest in asthma home-monitoring in children, there is a paucity of scientific evidence, especially on multi-parameter monitoring approaches. Therefore, the aim of this study is to investigate whether asthma control can be correctly assessed in the home situation by combining parameters from respiratory physiology sensors. Sixty asthmatic and 30 healthy children were enrolled in the observational WEARCON-study. The paediatrician assessed asthma control according to GINA guidelines. All children were also evaluated during a 2-week home-monitoring period with wearable devices; a physical activity tracker, a handheld spirometer, smart inhalers, and an ambulatory electrocardiography device to monitor heart and respiratory rate. Multiple logistic regression analysis was used to determine which diagnostic measures were associated asthma control. All 27 of the 27 uncontrolled asthmatic children and 31 of the 32 controlled asthmatic children could correctly be identified with this model. The final model showed that a larger variation in pre-exercise lung function (OR=1.36 95%-CI 1.06-1.75), an earlier wake-up-time (OR=1.06 95%-CI 1.01-1.11), more reliever use (OR=1.14 95%-CI 1.05-1.24) and a longer respiratory rate recovery time (OR=1.18 95%-CI 1.04-1.34) were significant contributors to the probability of having uncontrolled asthma. Home-monitoring of physiological parameters is associated with paediatrician assessed asthma control. The constructed multivariate model identifies 100% of all uncontrolled asthmatic children, indicating a high potential for monitoring of asthma control. This may allow healthcare professionals to assess asthma control at home. Trial registration: Netherlands Trail Register, NL6087. Registered 14 February 2017, https://www.trialregister.nl/trial/6087

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