Escape-from-Shock Training following Exposure to Inescapable Shock

1956 ◽  
Vol 2 (1) ◽  
pp. 43-49 ◽  
Author(s):  
James A. Dinsmoor ◽  
Sam L. Campbell
Keyword(s):  
Inescapable Shock ◽  
Escape Response ◽  
High Strength ◽  
Prior Exposure ◽  
Initial Slope ◽  
Rapid Decline ◽  
Low Strength ◽  
Shock Training

In this experiment we have studied the effects of exposing rats to non-terminable shock on their subsequent utilization of bar pressing as a means of terminating the shock. Our main findings were: (a) that a 15-min. period of prior exposure significantly delayed the first press in training and significantly reduced the number of presses within a 35-min. session; and (b) that a 15-min. period of exposure between training and extinction altered the shape rather than the initial slope of the extinction curves, producing a significantly more rapid decline in the rate of pressing. These results indicate that competing behavior is acquired when no authorized escape response is available, and that this behavior interferes with the escape response when this is at a low strength but is itself suppressed when the escape response is at a high strength.

COPPER ALLOY No. 165

Alloy Digest ◽  
1977 ◽  
Vol 26 (2) ◽  
Keyword(s):  
Corrosion Resistance ◽  
Physical Properties ◽  
Tensile Properties ◽  
Copper Alloy ◽  
High Strength ◽  
Heat Treating ◽  
High Ductility ◽  
Electrical Conductor ◽  
Annealed Condition ◽  
Low Strength

Abstract Copper Alloy No. 165 is a copper-cadmium-tin alloy with low strength and high ductility in the annealed condition. In the hard-drawn condition, characterized by high strength and low ductility, it is used widely as an electrical conductor. This datasheet provides information on composition, physical properties, hardness, elasticity, and tensile properties as well as fatigue. It also includes information on corrosion resistance as well as forming, heat treating, machining, and joining. Filing Code: Cu-327. Producer or source: Copper and copper alloy mills.

scholarly journals Impact of NPS MedicineWise General Practitioner education programs and Choosing Wisely Australia recommendations on prescribing of Proton Pump Inhibitors in Australia

2019 ◽  
Author(s):  
Jianyun Wu ◽  
Scott Dickinson ◽  
Zain Elgebaly ◽  
Suzanne Gaye Blogg ◽  
Aine Heaney ◽  
...  
Keyword(s):  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
High Strength ◽  
Choosing Wisely ◽  
Education Programs ◽  
Time Series Analyses ◽  
Low Strength ◽  
Practitioner Education ◽  
The Impact ◽  
Pharmaceutical Benefits Scheme

Abstract Background This study evaluated the impact of multifaceted NPS MedicineWise programs conducted in 2009 and 2015 that targeted general practitioners (GPs) to reduce unnecessary prescribing of proton pump inhibitors (PPIs). Methods Time series analyses of the dispensing rates of concessional PPI scripts between January 2006 and June 2016 using the Pharmaceutical Benefits Scheme (PBS) and Medicare Benefits Schedule (MBS) databases in Australia. Participants were GPs with dispensed PPI prescriptions to concessional patients between January 2006 and June 2016. The interventions were National NPS MedicineWise PPI educational programs in 2009 and 2015 delivered to all practising GPs in Australia. The 2015 intervention coincided with the release of Choosing Wisely Australia recommendations from the RACGP. Outcome measures included monthly dispensing rates of standard and low strength PPIs prescribed by GPs among concessional patients in Australia. Results Following the 2009 NPS MedicineWise program we observed a 6.7% reduction in the expected dispensing rate of standard strength PPIs among concessional patients between January 2006 and March 2015, and a total 8.6% reduction by June 2016 following the launch of the 2015 program. We observed a significant increase of 5.6% in the expected dispensing rate of low strength PPIs among concessional patients between April 2009 and March 2015, and no significant change in trend following the 2015 program. Conclusions The NPS MedicineWise programs were associated with reductions in the dispensing rate of standard strength PPIs, and with an increase in the dispensing rate of low-strength PPIs by June 2016. Although the rate of high-strength PPI prescribing is declining, these formulations still constitute the majority of PPI use in Australia. Regular interventions to sustain and improve PPI management by GPs may be warranted.

scholarly journals Comparative effectiveness and safety of low-strength and high-strength direct oral anticoagulants compared with warfarin: a sequential cohort study

BMJ Open ◽  
2019 ◽  
Vol 9 (5) ◽  
pp. e026486 ◽  
Author(s):  
Nicole L Pratt ◽  
Emmae Ramsay ◽  
Lisa M Kalisch Ellett ◽  
Katherine Duszynski ◽  
Sepehr Shakib ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Cohort Study ◽  
Propensity Score ◽  
Ischaemic Stroke ◽  
Oral Anticoagulants ◽  
Direct Oral Anticoagulants ◽  
High Strength ◽  
Risk Of Bleeding ◽  
Increased Risk ◽  
Low Strength

ObjectivesThe aim of this study was to compare effectiveness and safety of low-strength and high-strength direct oral anticoagulants (DOACs) with warfarin in the Australian Veteran population.DesignSequential cohort study using inverse probability of treatment weighting (IPTW) and propensity score matching. Initiators of high-strength (apixaban 5 mg, dabigatran 150 mg, rivaroxaban 20 mg) and low-strength DOACS (apixaban 2.5 mg, dabigatran 110 mg, rivaroxaban 15 mg) were compared with warfarin initiators.SettingAustralian Government Department of Veterans’ Affairs claims database.Participants4836 patients who initiated oral anticoagulants (45.8%, 26.0% and 28.2% on low-strength, high-strength DOACs and warfarin, respectively) between August 2013 and March 2015. Mean age was 85, 75 and 83 years for low-strength, high-strength DOACs and warfarin initiators, respectively.Main outcome measuresOne-year risk of hospitalisation for ischaemic stroke, any bleeding event or haemorrhagic stroke. Secondary outcomes were 1-year risk of hospitalisation for myocardial infarction and death.ResultsUsing the IPTW method, no difference in risk of ischaemic stroke or bleeding was found with low-strength DOACs compared with warfarin. As a class, no increased risk of myocardial infarction was found for low-strength DOACs, however, risk was elevated for apixaban (HR 2.25, 95% CI 1.23 to 4.13). For high-strength DOACs, no difference was found for ischaemic stroke compared with warfarin, however, there was a significant reduction in risk of bleeding events (HR 0.63, 95% CI 0.44 to 0.89) and death (HR 0.40, 95% CI 0.28 to 0.58). Propensity score matching showed no difference in risk of ischaemic stroke or bleeding.ConclusionWe found that in the practice setting both DOAC formulations were similar to warfarin with regard to effectiveness and had no increased risk of bleeding.

Anaerobic treatment of landfill leachate by sulfate reduction

2000 ◽  
Vol 41 (3) ◽  
pp. 239-246 ◽  
Author(s):  
J.G. Henry ◽  
D. Prasad
Keyword(s):  
Landfill Leachate ◽  
High Surface ◽  
High Strength ◽  
Anaerobic Treatment ◽  
Cod Removal ◽  
Sulphate Reduction ◽  
High Rate ◽  
Organic Loading Rate ◽  
Filter Performance ◽  
Low Strength

The present study was conducted to investigate the effectiveness of the sulphate-reduction pathway in the anaerobic treatment of landfill leachate. The effects of several COD/SO4 ratios (keeping COD constant) and loadings on anaerobic filter performance were studied and compared with the results from anaerobic filters which followed the methanogenic pathway. Results indicated that the treatability of leachate by sulphate reducing bacteria (SRB) was dependent upon the leachate strength. With high strength leachate (COD=15000 mg/L) from the Keele Valley Landfill, it was found that at lower COD/SO4 ratios (≤1.6) toxic conditions developed in the system that were more inhibitory to the SRB than to the methane producing bacteria (MPB). As the COD/SO4 ratio increased, methanogenesis predominated. No predominance of SRB occurred at any COD/SO4 ratio with high strength leachate. The highest COD removal achieved was about 70% of which 20% was accomplished by the SRB at a COD/SO4 ratio of 1.6 and an organic loading rate (OLR) of 4 kg COD/m3.d. With low strength leachate (COD=1500-3300 mg/L) from the Brock West Landfill, and a COD/SO4 ratio <1, SRB became predominant. In these anaerobic filters in which SRB were predominant, the SRB reduced the COD as well as the MPB could. Sulphide inhibition did not take place at any loading in units treating low strength leachate. Consequently, both SRB and MPB should function at COD/SO4 ratios between 1 and 3. About 60% COD removal was achieved at a loading of 2.8 kg COD/m3.d and a COD/SO4 ratio of 1.0. However at a loading of 6 kg COD/m3.d only 27% COD removal was achieved, all of it through the sulphate-reduction pathway. These OLR values are comparable to those applied in systems where methanogenesis was dominant. It was also observed that once the methanogens were established in the units, it was not possible to displace them completely. However, where methanogenesis had not been previously established, it was found that sulphate-reduction could be the sole pathway for COD removal. From this study, it can be concluded that there is no advantage to the sulphate-reduction pathway in the anaerobic treatment of landfill leachate. The other options for increasing the loadings, i.e. the use of high surface/volume filter media (to achieve higher biomass concentrations) or high rate systems are likely to be more successful.

scholarly journals Biosorption of Zn(II) in High and Low Strength Synthetic Wastewater by Watermelon Rind (Citrullus lanatus)

2015 ◽  
Vol 773-774 ◽  
pp. 1286-1290 ◽  
Author(s):  
M.F.H. Azizul-Rahman ◽  
A.A. Mohd Suhaimi ◽  
Norzila Othman
Keyword(s):  
Heavy Metal ◽  
Contact Time ◽  
Metal Removal ◽  
Citrullus Lanatus ◽  
Heavy Metal Removal ◽  
High Strength ◽  
Synthetic Wastewater ◽  
Watermelon Rind ◽  
Optimum Ph ◽  
Low Strength

The heavy metal contain in the industrial wastewater can cause a pollution towards the environment and human due to its toxicity. Therefore extensive studies were conducted for the heavy metal removal. This study was conducted under several conditions by varying pH, biosorbent dosage, initial wastewater concentration and contact time. The results revealed that optimum pH, for high strength synthetic wastewater was 8.0 meanwhile for low strength synthetic wastewater was 7.0. Both high and low strength synthetic wastewater was optimum at 30 minutes of contact time with 1.5g and 0.02g of bisorbent dosage respectively. Meanwhile, the optimum initial metal concentration for high and low strength synthetic wastewater was 400ppm and 1ppm respectively. The results had proven that watermelon rind is able to treat wastewater with high and low concentration of metal.

scholarly journals Overweight/Obese Schoolchildren with Low Muscle Strength Have a Lower Cardiorespiratory Capacity and Greater Cardiovascular Risk: Results of the School Health Survey of the Extreme South of Chile 2019

Children ◽  
2021 ◽  
Vol 8 (9) ◽  
pp. 734
Author(s):  
Javier Albornoz-Guerrero ◽  
Rafael Zapata-Lamana ◽  
Daniel Reyes-Molina ◽  
Igor Cigarroa ◽  
Guillermo García Pérez de Sevilla ◽  
...  
Keyword(s):  
Cardiovascular Risk ◽  
Muscle Strength ◽  
Muscular Strength ◽  
High Strength ◽  
Normal Weight ◽  
Overweight And Obesity ◽  
Obese Group ◽  
Height Ratio ◽  
Waist To Height Ratio ◽  
Low Strength

Objective: To compare cardiovascular risk and cardiorespiratory capacity in schoolchildren from a region in the extreme south of Chile according to nutritional status and muscular strength. Methods: An analytical cross-sectional study was performed on a sample of 594 schoolchildren from 5th to 8th grade in the extreme south of Chile. Based on body mass index and lower limb muscle strength, participants were divided into four groups: high strength-normal weight, high strength-overweight/obese, low strength-normal weight, and low strength-overweight/obese. Then, waist-to-height ratio and cardiorespiratory capacity, measured with the 20 m shuttle run test, were assessed to determine their cardiovascular risk, comparing the four groups. Results: The overweight/obese group with high muscular strength presented better indicators in anthropometric variables (waist circumference and waist-to-height ratio) than their peers with low muscular strength. Additionally, the overweight/obese group with low muscular strength presented a lower cardiorespiratory capacity than their peers with high muscular strength. Both results were observed in boys and girls. Conclusion: The results of this study suggest that overweight/obese schoolchildren with high muscle strength present healthier anthropometric indicators and greater cardiorespiratory capacity than their peers with low muscle strength. These results confirm the relevance of measuring muscle strength in schoolchildren and its usefulness to assess functionality. These results encourage the scientific community to continue studying the role that muscle strength plays in modulating the effects of overweight and obesity on respiratory and cardiovascular conditions in childhood.

scholarly journals Mechanical Characteristics and Failure Modes of Low-Strength Rock Samples with Dissimilar Fissure Dip Angles

2021 ◽  
Author(s):  
Y L Wang ◽  
D S Liu ◽  
K Li ◽  
X M Hu ◽  
D Chen
Keyword(s):  
Rock Mass ◽  
Mechanical Characteristics ◽  
Failure Modes ◽  
High Strength ◽  
Rock Masses ◽  
Deformation And Failure ◽  
Deformation Features ◽  
Low Strength ◽  
Dip Angle ◽  
Strength Rock

The mechanical characteristics and failure modes of low-strength rock sample with various fissure dip angles were investigated by conventional uniaxial compression test and three-dimensional (3D) crack reconstruction. The results indicated that compared with high-strength rock masses, cracks had different influences on the low-strength rock mass mechanical deformation features. Thereinto, the dip angle of fissures can cause post-peak failure stage of stress-strain curve change from swift decline to multi-step down, showing obvious ductility deformation and failure characteristics. Peak strength and elastic modulus owned an anti-S-shaped growth tendency with the growth of fissure dip angle, which was positively correlated and greatest subtle to the fissure dip angle α < 21° and α > 66.5°. The axial peak strain reduced first and enlarged rapidly with growing fissure dip angle, suggesting a V-shaped change trend. Increasing the fissure dip angle will change the sample failure mode, experienced complete tensile failure to tensile-shear composite failure, and ultimately to typical shear failure. Also, the crack start angle decreased with enlarging fissure dip angle, larger than that the high-strength rock mass fissure dip angle. The above research findings can complement and improve the study of fissured rock masses.

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