scholarly journals Does Oxygen Uptake Before Physical Exercise Affect Tear Osmolarity?

2020 ◽  
Vol 73 (1) ◽  
pp. 297-304
Author(s):  
Adam Wylęgała ◽  
Jan Pilch ◽  
Bartłomiej Bolek ◽  
Bogumiła Sędziak-Marcinek ◽  
Edward Wylęgała

AbstractRecently, it has been reported that tear osmolarity (Tosm) is correlated with plasma osmolarity and will increase during exertion. We aimed to assess whether inhaling oxygen-enriched air between exercises could significantly change the Tosm value. Thirty men aged 24.9 years were included in the study. A cycloergometer was used to perform the exercise protocol. We recorded the participants’ Tosm (mOsm/L), heart rate (HR, beats/minute), oxygen saturation, and blood pressure values. After the first exhaustive exercise (T1), participants inhaled oxygen in the experimental group and a placebo in the control group. After the second exercise (T2), another set of measurements was obtained. The Tosm value before exercise was 297.4 ± 1.21 and 296.53 ± 1.11 mOsm/L (p = 0.61718) and the HR was 72.6 ± 2.59 and 73 ± 2.59 beats/minute (p = 0.39949) in the study and the control group, respectively. At T1, Tosm was 303.67 ± 1.25 and 302.2 ± 1.25 mOsm/L (p = 0.41286) and the HR reached 178.04 ± 2.60 and 176.4 ± 2.60 beats/minute (p = 0.65832), respectively. At T2, Tosm in the study group reached 305.73 ± 0.86 mOsm/L (correlation with the use of oxygen: r = −0.3818), and in the control group, it was 308.4 ± 0.86 mOsm/L (p = 0.0373), while the HR reached 172.20 ± 2.53 beats/minute in the study group and 178.2 ± 2.53 beats/minute in the control group (p = 0.057). It was concluded that inhaling oxygen before and after exercise could increase the rate of recovery after exhaustive exercise.

2020 ◽  
Vol 9 (3) ◽  
pp. 622
Author(s):  
Elia Lopez-Yufera ◽  
Pia López-Jornet ◽  
Oscar Toralla ◽  
Eduardo Pons-Fuster López

Objective: To evaluate the effect of a music intervention upon anxiety, blood pressure, and heart rate in adult patients with potentially malignant oral disorders. Methods: Eighty consecutive adults (mean age: 68.3 years) consulting a Unit of Oral Medicine (Murcia Spain) were randomized to a study group (n = 40) that listened to music through headphones during 10 min or to a control group (n = 40). Corah’s dental anxiety score, blood pressure, heart rate, oxygen saturation (oximetry), skin temperature, and salivation were recorded at different timepoints before and after patient consultation. Results: Significant pre- versus post-consultation reductions were observed in blood pressure (p < 0.001) and heart rate (p < 0.001), though not in temperature, salivation, and oxygen saturation (p > 0.05). There were no significant differences between the study group and the controls (p > 0.05). Conclusions: The applied music intervention had no apparent effect upon anxiety. Further studies using different music intervention strategies and/or analytic parameters are needed to explore the benefits of this approach to decreasing anxiety.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Menglu Jiang ◽  
Jiawei Ji ◽  
Xin Li ◽  
Zhenqing Liu

Abstract Background Endotracheal intubation and extubation may cause undesirable hemodynamic changes. Intravenous oxycodone has recently been introduced and used for relieving hemodynamic alterations in response to intubation, but there is insufficient information regarding its application in stabilizing hemodynamics during extubation in the patients emerging from general anesthesia. Methods One hundred patients, who had undergone assorted laparoscopic surgeries under general anesthesia, were randomly assigned to Control group (saline injection, 50 cases) and Study group (intravenous injection of 0.08 mg/kg oxycodone immediately after completion of the surgical procedure, 50 cases). Blood pressure, heart rate, blood oxygen saturation (SpO2) as well as blood concentrations of epinephrine, norepinephrine, and cortisol were recorded or measured immediately before extubation (T0), during extubation (T1), as well as one minute (T2), 5 min (T3), and 10 min after extubation (T4). In addition, coughing and restlessness, time of eye-opening, and duration from completing surgery to extubation as well as Ramsay Sedation Scale were analyzed. Results Blood pressure and heart rate as well as blood concentrations of epinephrine, norepinephrine, and cortisol were significantly higher in the Control group compared with the Study group at the time of extubation as well as 1, 5, and 10 min after extubation (P < 0.05). When the patients emerged from general anesthesia, 70 % of the Control group had cough, which was significantly higher than that of Study group (40 %, P < 0.05). Significantly higher number of patients manifested restlessness in the Control group before (40 %) and after extubation (20 %) compared with that in the Study group (20 and 2 %, respectively, P < 0.05). In addition, patients of Control group had lower Ramsay score at extubation (1.7 ± 0.7) as well as 30 min after extubation (2.4 ± 0.9) compared to that of the patients of Study group (2.2 ± 0.9, and 3.0 ± 0.8, respectively, P = 0.003 and 0.001). Conclusions Intravenous oxycodone attenuated alterations of hemodynamics and blood hormones associated with extubation during emergence from general anesthesia. Trial registration Chinese Clinical Trial Registry: ChiCTR2000040370 (registration date: 11-28-2020) “‘retrospectively registered”.


1994 ◽  
Vol 79 (3) ◽  
pp. 1391-1397 ◽  
Author(s):  
Sherman D. Vanderark ◽  
Daniel Ely

Physiological responses associated with the ratings of musical stimuli were investigated. For 101 university music and biology students in the experimental group, heart rate, blood pressure, and finger temperature were measured before and after listening to about 10 min. of music (Venus and Jupiter from Holst's The Planets) in an anechoic chamber. They also served as their own controls by sitting in silence for about 10 min. No significant differences were found on the three measures for the two musical stimuli between the musical or control conditions or between the two majors.


2021 ◽  
Vol 5 (4) ◽  
pp. 220-224
Author(s):  
Chengxi Chi ◽  
Mengmeng Zhao ◽  
Jiajing He ◽  
Yanli Wang

Objective: To investigate and analyze the anesthetic effect of compound artevacaine hydrochloride in patients undergoing oral implantation. Methods: In this study, 60 patients receiving oral implant surgery in our hospital were selected as the research subjects, and the operation time was from July 2019 to March 2021. Patients were randomly selected and divided into groups for the study. 30 patients receiving lidocaine hydrochloride anesthesia were used as the control group, and 30 patients receiving compound artevacaine hydrochloride anesthesia were used as the research group. The anesthetic effect and safety of the two groups were compared and analyzed. Results: The anesthetic effect of the study group was significantly better than that of the control group (P < 0.05). The blood pressure and heart rate in the study group were significantly lower than those in the control group (P < 0.05). There was no significant difference in blood pressure and heart rate between the two groups before anesthesia (P > 0.05). There was no significant difference in the incidence of ADR between the two groups (P > 0.05). Conclusions: For patients undergoing oral implant surgery, choosing compound artevacaine hydrochloride as anesthetic drug has obvious anesthetic effect and can stabilize patients' life indexes. The anesthetic effect is obvious, and there is no obvious adverse reaction, and the clinical value is obvious.


2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Areeg E. Elemam ◽  
Nisreen D. Omer ◽  
Neima M. Ibrahim ◽  
Ahmed B. Ali

Background. The current study investigated the effect of dipping tobacco (DT) use on arterial wall stiffness which is a known marker of increased risk of cardiovascular events. Methods. A case-control study which included 101 adult males was carried out in Al-Shaab Teaching Hospital. Blood pressure and pulse wave analysis parameters were recorded in 51 DT users (study group) before and after 30 minutes of placing tobacco and in 50 nontobacco users (control group). Anthropometric measurements were collected using data collection sheet. Data were entered into a computer and analyzed by using the software Statistical Package for the Social Sciences (SPSS) version 20 (SPSS Inc., Chicago, IL, USA). Results. At baseline measurements, heart rate (HR) was significantly lower in the study group compared to the control group ( 66.15 ± 9.21 vs. 72.87 ± 10.13 beats/min; P value ≤ 0.001). Subendocardial viability ratio (SEVR) was significantly higher in the study group compared to the control group ( 203.44 ± 30.34 vs. 179.11 ± 30.51 % ; P value ≤ 0.001). Acute effects of DT compared to pretobacco dipping showed significant increase in HR ( 72.50 ± 10.89 vs. 66.15 ± 9.21 beats/min; P value ≤ 0.001) and significant decrease in augmentation pressure (AP) (4.30 (2.30-8.00) vs. 3.30 (0.60-6.3) mmHg; P value ≤ 0.001), ejection duration (ED) ( 271.65 ± 19.42 vs. 279.53 ± 20.47   ms ; P value ≤ 0.001), and SEVR ( 187.11 ± 29.81 vs. 203.44 ± 30.34 ; P value ≤ 0.001). Linear regression analysis for AP predictor showed that only HR and AIx@75 affect and predict the values of AP ( Beta ± SE ; − 0.242 ± 0.019 , P value ≤ 0.001; 0.685 ± 0.014 , P value ≤ 0.001). Conclusions. Long-term use of DT was not associated with permanent changes in heart rate and blood pressure. Acute tobacco dipping caused an acute increase in heart rate and oxygen demands of myocardium.


Author(s):  
Odgerel B. ◽  
Sergelen O. ◽  
Ganbold L.

Objective: The aim of this study was to evaluate of analgesic effect of ultrasound guided transversus abdomines plane (TAP) block in children undergoing open laparotomy surgery and compare to children were used general anesthesia (GA) alone. Methods: 60 children aged 3-18 years with ASA I-III classification were randomly enrolled in this study. We divided these children in to two groups: control group (GA alone, n=31) and study group (GA+TAP block, n=29) and also divided each group in two subgroups which were with inflammation and without inflammation. All children were received GA with same techniques. Study group (TAP block group) were assigned to receive ultrasound guided block in both side of abdomen using 0.3 ml/kg of Bupivacaine 0.25%, but not more than 12 ml in each side. Hemodynamic variables such as heart rate, blood pressure were measured at baseline (T0), after induction (T1), after skin incision (T2), and end of surgery (T3), and in the recovery room or ICU, at the 2nd, 4th, 6th hours  postoperatively and examined pain intensity and analgesic requirement and frequency, also correllation between inflamatory process and pain intensity were studied. Statistic analysis was made in Excel using ANOVA, descriptive analysis, correlation and regression analysis. A p-value<0.05 was considered significant. Results: There was no differencies between the two studied groups regarding demographic and clinical characteristics. Intraoperative heart rate elevation was higher in GA group with an inflammation (13.3%) and the systolic blood pressure changes was higher (4.2%) after skin incision than study group and GA group without inflammation.  Level of WBC had very weak positive and statistically significant correlation with intraoperative opioid usage (GA+Inf: r=0.029, p=0.023; ТAP+Inf: r=0.18, p=0.016; GA-Inf: r=0.018, p=0.014) but there was not observed correlation in TAP-Inf group. Postopeative pain score was higher in control group and an analgesic requirement and frequency was much more. Conclusion: Transversus abdomines plane block under ultrasound guidance was easy, safe, reliable and effective analgesic in children undergoing open laparotomy surgery and TAP block is a good component of postoperative multimodal analgesia. The inflammatory process increases pain intensity and intra and postoperative analgesic requirements.


Author(s):  
Kristýna Machová ◽  
Radka Procházková ◽  
Michal Říha ◽  
Ivona Svobodová

A stroke is a condition that can give rise to consequences such as cognitive and physical constraints, which sometimes manifest in the psychological condition of the patient. Such patients commence rehabilitation as soon as is possible, which involves a multi-disciplinary approach to treatment. One aspect of complementary rehabilitation could be animal-assisted therapy (AAT). A total of 15 individuals were split into an experimental group comprising 6 patients (2 males, 4 females), and a control group of 9 patients (3 males, 6 females). The participants in the control group were aged from 43 to 87 years and the experimental group featured participants aged from 45 to 76 years. Both groups received standard physiotherapy and occupational therapy. In addition, the experimental group was supplemented with AAT, with the animal in question being a dog. The tools primarily applied to measure the outcomes were the Barthel index, blood pressure, and heart rate measurements, whereas the Likert scale was employed to discern the mood of the patients. The results showed that changes in the values for heart rate and blood pressure were insignificant. However, a statistically significant aspect of the research pertained to the patients confirming that they felt better after the AAT sessions. Hence, AAT could potentially bolster the effectiveness of other therapies.


2020 ◽  
Vol 3 (2) ◽  
pp. 82-90
Author(s):  
Andalia Roza ◽  
Nalaratih Nalaratih ◽  
Yulia Febrianita

High blood pressure or hypertension is a state where a person experiences an increase in blood pressure above normal figures indicate the upper number (systolic) reached 140 mmHg, and the bottom number (diastolic) reaches above 90mmHg. Patients with hypertension in the world reached 1 billion, or 1 out of 4 adults. Hypertension caused 1 of 7 deaths or totaled 7 million annually that cause damage to heart, brain, eyes, and kidneys. The objective of study was to find out the effectiveness of coconut water on the reduction of blood pressure in patients with hypertension. This type of research was quasy experiment with non-equivalet research design. The population of study were all the people in Beringin Makmur Village RT 01 RW 01 Pelalawan District Riau Province aged 30-50 years with hypertension who meet the criteria. The sample of study amounted to 30 people. The sampling technique was taken using total sampling method. The sample of study consisted of two groups as the experimental group and the control group, then followed by pretest in both groups and the intervention in the experimental group. There were significant differences in blood pressure (both systolic and diastolic) final adult patients with hypertension before and after the control group in Beringin Makmur Village Pelalawan District Riau Province p-value for sistole 0.334 and p-value 0.253 for diastolic p-value > 0.05. The result of study indicates means that the coconut water therapy effective in lowering blood pressure in patients with hypertension. More people were expected to know that coconut water could lowering blood pressure and prevent hypertension.


2021 ◽  
Vol 71 (3) ◽  
pp. 1033-36
Author(s):  
Fatima Iqbal ◽  
Manzoor Ahmed Faridi ◽  
Aisha Saeed ◽  
Inamullah Shah

Objective: To compare the result of the combination of hyperbaric bupivacaine plus fentanyl with hyperbaric bupivacaine alone in patients undergoing caesarean section in spinal anaesthesia. Study Design: Comparative, cross-sectional study. Place and Duration of Study: Department of Anesthesia, Fauji Foundation Hospital, Rawalpindi Pakistan, from Dec 2017 to Jun 2018. Methodology: After consulting the institutional ethical review committees a total of 60 females between ages 18-40 years were enrolled for caesarean section delivery. They were divided into two groups. The study group (n=30) received a subarachnoid injection of 0.5% hyperbaric bupivacaine (10mg) 2ml with 25ug of fentanyl 0.5ml and control group (n=30) was injected 0.5% hyperbaric bupivacaine 12.5mg (2.5 ml) only. Pain experienced during the procedure was assessed by using 10-point visual analogue scoring method. The mean duration of analgesia, mean arterial blood pressure and heart rate after surgery were compared between two groups. Results: The mean duration of analgesia was 206.5/min ± 6.4 in the study group and it was 163.6min ± 7.2 in the control group (p=0.001). Mean arterial BP after surgery was 92.3mmHg ± 3.8 in the study group and 88.7mmHg ± 4.1 in the control group (p=0.001). The mean heart rate recorded after surgery was 75.2/min ± 5.2 in the study group and it was 70.4/min ± 6.1 in the control group (p=0.001). Conclusions: The mean duration of analgesia was significantly longer in the study group when compared with the control group with better mean arterial blood pressure and heart rate response after Caesarean section.


2014 ◽  
Vol 04 (02) ◽  
pp. 027-033
Author(s):  
Anuja B. S. ◽  
Elsa Sanatombi Devi ◽  
Leena Sequira ◽  
Lavanya Rao ◽  
Vijaya Pai H.

Abstract: Introduction: Patients who are undergoing cataract surgery under local anaesthesia may be more stressed than those having general anaesthesia as they are awake during the surgical procedure. Therefore, psychological comfort in the preoperative phase and compliance during operation are very important for postoperative prognosis. This study explored the pre operative anxiety level of patients undergoing cataract surgery and the effectiveness of intra operative hand holding on anxiety and its related physiological parameters. Methods: A quasi experimental pre-test post-test control group design was used to collect data from a purposive sample of 54 patients who were underwent cataract surgery at Kasturba Hospital, Manipal. Results: Most of the patients in the experimental group perceived intra operative hand holding as a measure to reduce their anxiety even though there was no significant statistical difference in the immediate post operative anxiety score between the groups. It was also found that hand holding was effective in reducing blood pressure and heart rate except the respiratory rate of patients undergoing cataract surgery. Conclusion: The following conclusions were drawn on the basis of the findings of the present study that is, Intra operative hand holding was effective in reducing the physiological parameters such as heart rate, systolic blood pressure and diastolic blood pressure. Also most of the patients perceived intra operative hand holding as beneficial in relieving anxiety.


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