scholarly journals Depression and Metabolic Syndrome: Two Sides of the Same Coin

2019 ◽  
Vol 12 (1) ◽  
pp. 3-9 ◽  
Author(s):  
George John ◽  
Mona Asghari ◽  
Vipin VP ◽  
Valsamma Eapen
Keyword(s):  
Cardiovascular Disease ◽  
Metabolic Syndrome ◽  
Depressive Symptoms ◽  
Psychological Factors ◽  
Related Factors ◽  
The Relationship ◽  
Two Sides

Summary This aim of this review was to examine the relationship between metabolic syndrome (MetS) and depression, which is complex and multifaceted with many inter-related factors includinggenetics, lifestylefactors, environmentalfactorsand other psychological factors at play. There is some evidence to suggest that depression may lead to the development of cardiovascular disease through its association with MetS. It has also been suggested that depressive symptoms may be a consequence rather than the cause of the MetS, as obesity and dyslipidemia have been shown as predictive of depressive symptoms. Thus, the relationship between MetS and depression seems to be a two-way street and bi-directional just as the two sides of the same coin.

scholarly journals Type D personality and metabolic syndrome among Finnish female municipal workers

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Susa Majaluoma ◽  
Tellervo Seppälä ◽  
Hannu Kautiainen ◽  
Päivi Korhonen
Keyword(s):  
Risk Factors ◽  
Cardiovascular Disease ◽  
Metabolic Syndrome ◽  
Depressive Symptoms ◽  
Leisure Time Physical Activity ◽  
Type D Personality ◽  
Female Population ◽  
Type D ◽  
Working Age ◽  
The Relationship

Abstract Background Type D personality is a combination of high negative affectivity (NA) and high social inhibition (SI). This personality trait is suspected to impair cardiovascular patients’ recovery. The 2016 European Guidelines on cardiovascular disease prevention in clinical practice recommend screening of psychosocial risk factors as Type D personality. The aim of this study was to assess the relationship between Type D personality and Metabolic syndrome (MetS) in working-age female population. Methods Six hundred thirty-four female employees with mean age of 48 ± 10 years were evaluated. Type D personality and its components (NA) and (SI) were screened with DS14 questionnaire. The definition of MetS was based on measurements done by trained medical staff. We investigated the relationship between Mets and Type D personality, NA and SI using the logistic regression models adjusting for age, education years, leisure-time physical activity, smoking, alcohol use and depressive symptoms. Results The prevalence of Type D personality was 10.6% (n = 67) [95% CI: 8.3 to 13.2] and MetS 34.7% (n = 220). Type D personality or its subcomponents were not associated with MetS. Women with Type D personality had significantly worse quality of sleep and lower LTPA. They were also more often unsatisfied with their economic situation, they had more often depressive symptoms and psychiatric disorders than non-D type persons. There were no differences in risk factors for cardiovascular diseases. Conclusion Screening for Type D personality among working- age, reasonably healthy female population seems not to be practical method for finding persons with risk for cardiovascular disease.

scholarly journals Relationship between Depressive Symptoms and Cardiovascular Disease Risk Factors in African American Individuals

2011 ◽  
Vol 2011 ◽  
pp. 1-6 ◽  
Author(s):  
Ali A. Weinstein ◽  
Preetha Abraham ◽  
Guoqing Diao ◽  
Stacey A. Zeno ◽  
Patricia A. Deuster
Keyword(s):  
Risk Factors ◽  
Cardiovascular Disease ◽  
African American ◽  
Depressive Symptoms ◽  
Disease Risk ◽  
Cardiovascular Disease Risk ◽  
Regression Analyses ◽  
Cvd Risk Factors ◽  
Cvd Risk ◽  
The Relationship

Objective. To examine the relationship between depressive symptoms and cardiovascular disease (CVD) risk factors in a group of African American individuals.Design. A nonrandom sample of 253 (age 43.7 ± 11.6 years; 37% male) African American individuals was recruited by advertisements. Data were obtained by validated questionnaires, anthropometric, blood pressure, and blood sample measurements.Results. Regression analyses were performed to assess the relationship between depressive symptoms and CVD risk factors controlling for socioeconomic status indicators. These analyses demonstrated that those with higher levels of depressive symptoms had larger waist-to-hip ratios, higher percent body fat, higher triglycerides, and were more likely to be smokers.Conclusions. It has been well documented that higher levels of depressive symptoms are associated with higher CVD risk. However, this evidence is derived primarily from samples of predominantly Caucasian individuals. The present investigation demonstrates that depressive symptoms are related to CVD risk factors in African American individuals.

scholarly journals Osteoprotegerin in Cardiometabolic Disorders

2015 ◽  
Vol 2015 ◽  
pp. 1-15 ◽  
Author(s):  
C. Pérez de Ciriza ◽  
A. Lawrie ◽  
N. Varo
Keyword(s):  
Risk Factors ◽  
Cardiovascular Disease ◽  
Metabolic Syndrome ◽  
Positive Relationship ◽  
Bone Remodelling ◽  
Potential Biomarker ◽  
Cardiometabolic Disorders ◽  
Obesity Hypertension ◽  
The Relationship

Osteoprotegerin (OPG), a glycoprotein traditionally implicated in bone remodelling, has been recently related to cardiovascular disease (CVD). Human studies show a positive relationship between circulating OPG, vascular damage, and CVD, and as such OPG has emerged as a potential biomarker for CVD. This review focuses on the relationship between circulating OPG and different endocrine cardiometabolic alterations such as type 1 and 2 diabetes. The association of OPG with diabetic complications (neuropathy, nephropathy, or retinopathy) as well as with atherosclerosis, coronary artery calcification, morbidity, and mortality is pointed out. Moreover, OPG modulation by different treatments is also established. Besides, other associated diseases such as obesity, hypertension, and metabolic syndrome, which are known cardiovascular risk factors, are also considered.

Weight gain over 3 kg is associated with worse metabolic syndrome indicators, regardless of weight gain recognition in Japanese workers

2016 ◽  
Vol 23 (13) ◽  
pp. 1711-1719 ◽  
Author(s):  
Shiori Toga ◽  
Yuko Fukkoshi ◽  
Rie Akamatsu
Keyword(s):  
Cardiovascular Disease ◽  
Metabolic Syndrome ◽  
Weight Gain ◽  
Japanese Workers ◽  
The Relationship

We examined the relationship between recognition of a 3-kg weight gain in 1 year with metabolic syndrome parameters and lifestyle status related to metabolic syndrome or cardiovascular disease in Japanese workers. Data were collected twice between April 2009 and March 2011, and self-reported questionnaires were completed at a follow-up by 275 workers who gained more than 3 kg in 1 year. This study showed that ~40 per cent of those who gained more than 3 kg in a year did not recognise their weight gain, and a weight gain over 3 kg was associated with worse metabolic syndrome parameters regardless of weight gain recognition.

scholarly journals Serum Bilirubin and Genes Controlling Bilirubin Concentrations as Biomarkers for Cardiovascular Disease

2010 ◽  
Vol 56 (10) ◽  
pp. 1535-1543 ◽  
Author(s):  
Jing-Ping Lin ◽  
Libor Vitek ◽  
Harvey A Schwertner
Keyword(s):  
Cardiovascular Disease ◽  
Metabolic Syndrome ◽  
Serum Bilirubin ◽  
Association Studies ◽  
Major Gene ◽  
Linkage Study ◽  
Cvd Risk ◽  
Related Factors ◽  
Genetic Interventions

BACKGROUND Serum bilirubin has been consistently shown to be inversely related to cardiovascular disease (CVD). Recent studies showed serum bilirubin to be associated with CVD-related factors such as diabetes, metabolic syndrome, and body mass index. Although the association of serum bilirubin with CVD has been found in both retrospective and prospective studies, less information is available on the role of genes that control bilirubin concentrations and their association with CVD. CONTENT In this review, we provide detailed information on the identity of the major genes that control bilirubin concentrations and their association with serum bilirubin concentrations and CVD risk. We also update the results of the major studies that have been performed on the association between serum bilirubin, CVD, and CVD-related diseases such as diabetes or metabolic syndrome. Studies consistently indicate that bilirubin concentrations are inversely associated with different types of CVD and CVD-related diseases. A conditional linkage study indicates that UGT1A1 is the major gene controlling serum bilirubin concentrations, and this finding has been confirmed in recent genomewide association studies. Studies also indicate that individuals homozygous for UGT1A1*28 have a significantly lower risk of developing CVD than carriers of the wild-type alleles. SUMMARY Serum bilirubin has a protective effect on CVD and CVD-related diseases, and UGT1A1 is the major gene controlling serum bilirubin concentrations. Pharmacologic, nonpharmacologic, or genetic interventions that increase serum bilirubin concentrations could provide more direct evidence on the role of bilirubin in CVD prevention.

scholarly journals Unraveling the genetic and environmental relationship between well-being and depressive symptoms throughout the lifespan

2018 ◽  
Author(s):  
Bart Baselmans ◽  
Yayouk Willems ◽  
Toos van Beijsterveldt ◽  
Lannie Ligthart ◽  
Gonneke WIllemsen ◽  
...  
Keyword(s):  
Depressive Symptoms ◽  
Genetic Predisposition ◽  
Genetic Correlations ◽  
Well Being ◽  
Phenotypic Correlation ◽  
Substantial Part ◽  
Phenotypic Variance ◽  
Environmental Correlations ◽  
The Relationship ◽  
Two Sides

Whether well-being and depressive symptoms can be considered as two sides of the same coin is widely debated. The aim of this study was to gain insight into the etiology of the association between well-being and depressive symptoms across the lifespan. In a cohort-sequential design, including data from 43,427 twins between age 7 and 99, we estimated the association between well-being and depressive symptoms throughout the lifespan and assessed genetic and environmental contributions to the observed overlap. For both well-being (range 31% –45%) and depressive symptoms (range 50%-61%), genetic factors explained a substantial part of the phenotypic variance across the lifespan. Correlations between well-being and depressive symptoms across ages ranged from -.34 in childhood to -.49 in adulthood. In children and adults (aged >27), environmental effects explained 51% to 59% of the phenotypic correlation, while for adolescents and young adults strong genetic influences (60%-77%) on the association were observed. Moderate to high genetic correlations (ranging from 0.60 to 0.70) were observed in adolescence and adulthood, while in childhood environmental correlations were substantial but genetic correlations small. These results suggest that environmental factors are important in explaining the relationship between well-being and depressive symptoms in childhood, while from adolescence onwards a genetic predisposition for higher well-being is indicative for a genetic predisposition for lower depressive symptoms, and vice versa. These results provided more insights into the etiological underpinnings of well-being and depressive symptoms, possibly allowing to articulate better strategies for health promotion and resource allocation in the future.

scholarly journals Analysis of the relationship between MCI and metabolic syndrome‐related factors in community residents over 50 years old

2020 ◽  
Vol 16 (S6) ◽  
Author(s):  
Yanrong Yang ◽  
Zheng LI ◽  
Yan Wang ◽  
Gaofeng Pan ◽  
Jianghong Wang ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Related Factors ◽  
Community Residents ◽  
The Relationship

597 Sleep Bruxism in Preschool Children: Associations with Emotional-Behavioral Problems

SLEEP ◽  
2021 ◽  
Vol 44 (Supplement_2) ◽  
pp. A235-A235
Author(s):  
Christine Laganière ◽  
Samantha Kenny ◽  
Hélène Gaudreau ◽  
Irina Pokhvisneva ◽  
Andrée-Anne Bouvette-Turcot ◽  
...  
Keyword(s):  
Socioeconomic Status ◽  
Depressive Symptoms ◽  
Behavioral Problems ◽  
Sleep Bruxism ◽  
Maternal Depressive Symptoms ◽  
Sleep Habits ◽  
Related Factors ◽  
Family Socioeconomic Status ◽  
Biological Sex ◽  
The Relationship

Abstract Introduction Several psychosocial factors contribute to the etiology of sleep bruxism in childhood, including emotional-behavioral problems, as well as environmental and familial factors. It is known that sleep bruxism is prevalent in preschoolers, but most etiology studies were conducted with school-aged children or adolescents. Studies focusing on younger, preschool-aged populations that consider family-related factors are lacking. This study aimed to assess the relationship between emotional-behavioral problems and the presence of sleep bruxism in preschoolers, while taking maternal depressive symptoms into consideration. Methods Three hundred eighty-three mother-child dyads from the Maternal Adversity, Vulnerability, and Neurodevelopment (MAVAN) cohort were included in the present study. Mothers completed the Child’s Sleep Habits Questionnaires (CSHQ; includes the frequency of bruxism), a questionnaire about their child’s emotional-behavioral problems (CBCL; anxiety and depressive problems), and reported their own depressive symptoms (CES-D). Measures were completed at two timepoints: when children were 4 and 5 years old. Generalized Estimating Equation (GEE) models were used to evaluate the relationship between sleep bruxism frequency and children’s emotional-behavioral problems, while controlling for maternal depressive symptoms, child’s biological sex, family socioeconomic status, and age. Results Maternal reports indicated that 12% of children experienced sleep bruxism at least sometimes at age four, and 20% did at age five. Children’s anxiety and depressive symptoms were associated with increased sleep bruxism frequency (p < 0.05). Associations between children’s emotional-behavioral problems and bruxism remained statistically significant when controlling for maternal depressive symptoms, child’s biological sex, family socioeconomic status, and time (p < 0.05). Conclusion In this normative cohort of children, sleep bruxism was associated with anxiety and depressive symptoms in children as young as age four. Furthermore, this relationship can still be observed when the severity of maternal depressive symptoms is considered. Whether anxiety and depressive symptoms contribute to sleep bruxism, or vice versa, remain to be further investigated. Nevertheless, results suggest that screening of emotional-behavioral problems should be considered in children experiencing sleep bruxism. Support (if any) Fonds de recherche du Québec - Santé

scholarly journals Association of Gender, Triglyceride/HDL Ratio, and Physical Activity of Obese Adolescents in Makassar

2020 ◽  
Vol 8 (T2) ◽  
pp. 81-86
Author(s):  
Nurhaedar Jafar ◽  
Aminuddin Syam ◽  
Yessy Kurniati ◽  
Een Kurnaesih ◽  
Reza Aril Ahri ◽  
...  
Keyword(s):  
Physical Activity ◽  
Cardiovascular Disease ◽  
Metabolic Syndrome ◽  
Metabolic Disorders ◽  
Density Lipoprotein ◽  
Chi Square ◽  
Cross Sectional ◽  
Obese Adolescents ◽  
Cross Sectional Design ◽  
The Relationship

BACKGROUND: Obesity may cause the increase of triglyceride and decrease of high-density lipoprotein (HDL) levels. Triglyceride/HDL ratio is associated with metabolic disorders. Physical activity is one of the important aspects in preventing obesity. Gender is known to have a relationship with these factors, but it has been inconsistent. AIM: This study aimed to evaluate the relationship between sex and triglycerides, levels of HDL, triglycerides/HDL ratio, and physical activity of obese adolescents in Makassar. METHODS: This study used a cross-sectional design involving 93 samples of obese adolescents from three high schools. Measurement of triglyceride and HDL levels was performed by the Prodia laboratory, while physical activity was measured using the International Physical Activity Questioner. Data analysis was performed with Chi-square and Fisher’s exact tests. RESULTS: The results showed that there is a relationship between gender and triglyceride levels (p = 0.006) and HDL (p = 0.034), but no relationship between the ratio of TG/HDL (p = 0.109) and physical activity was found (p = 0.339). CONCLUSION: Efforts should be made to reduce the level of risk adolescent obesity on the risk of metabolic syndrome and cardiovascular disease, including increase physical activity. Physical activity is important to maintain the physical and mental of obese adolescents.

scholarly journals Metabolic Syndrome and Periodontitis: Is Oxidative Stress a Common Link?

2009 ◽  
Vol 88 (6) ◽  
pp. 503-518 ◽  
Author(s):  
P. Bullon ◽  
J.M. Morillo ◽  
M.C. Ramirez-Tortosa ◽  
J.L. Quiles ◽  
H.N. Newman ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Blood Pressure ◽  
Cardiovascular Disease ◽  
Metabolic Syndrome ◽  
Density Lipoprotein ◽  
Serum Levels ◽  
Inflammatory State ◽  
Anti Oxidant ◽  
Obesity Hypertension ◽  
The Relationship

A review of pathological mechanisms that can explain the relationship between periodontitis and cardiovascular disease (CVD) is necessary to improve the management of both conditions. Metabolic syndrome is a combination of obesity, hypertension, impaired glucose tolerance or diabetes, hyperinsulinemia, and dyslipidemia. All these have been examined in recent years in terms of their relationship to periodontitis. Reviewed data indicate an association between some of them (body mass index, high-density lipoprotein-cholesterol [HDL-C], triglycerides, high blood pressure, among others) and periodontitis. Oxidative stress may act as a potential common link to explain relationships between each component of metabolic syndrome and periodontitis. Both conditions show increased serum levels of products derived from oxidative damage, with a pro-inflammatory state likely influencing each other bidirectionally. Adipocytokines might modulate the oxidant/anti-oxidant balance in this relationship.

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