scholarly journals Diagnostic Central Obesity Indexes Cut – Off Point Values Determined with Dual-Energy X-Ray Absorptiometry in Cushing’s and Obese Women

PRILOZI ◽  
2020 ◽  
Vol 41 (3) ◽  
pp. 13-21
Author(s):  
Slavica Shubeska Stratrova ◽  
Sasha Jovanovska Mishevska ◽  
Iskra Bitoska ◽  
Irena Kafedziska
Keyword(s):  
Body Fat ◽  
Abdominal Obesity ◽  
Central Obesity ◽  
Visceral Obesity ◽  
Fat Distribution ◽  
Dual Energy ◽  
Obese Women ◽  
X Ray ◽  
Normal Body ◽  
Diagnostic Criterion

AbstractAim: The aim of this study was to develop quantiative criteria for defining visceral obesity and to establish dual-energy X-ray absorptiometric (DXA) diagnostic cut-off points (CP) for normal and abnormal values of the central obesity indexes (COI) that best differentiate extreme visceral obesity in Cushing’s syndrome (CS) from non CS obese and non obese women.Material and Methods: COI1–4 values calculated as a ratio of android to gynoid tissue mass, fat mass and their % were determined in 4 groups, each consisting of 18 women: 1st group of CS, 2nd group of obese women (O1) not different according to their age and BMI from CS, 3rd group of obese women (O2) with BMI of 35 ± 1.2 kg and 4th group of non obese healthy women (C) with normal BMI. Diagnostic accuracy (DG) of CP values of COI1m-4m indexes of abdominal obesity and CP values of COI1n-4n indexes of normal body fat distribution (BFD) was determined.Results: COI1-4 indexes values were highly significantly different among the 4 examined groups and were significantly highest in CS patients and lowest in group C (p < 0.0001). COI1m-4m CP values differentiated extreme visceral, abdominal obesity in CS with highest DG as well as COI1n-4n CP values differentiated normal BFD in group C. COI1m CP of 0.55 best differentiated CS from O1 for DG of 100%. COI2n of 0.38 best differentiated C from CS and O2 for highest DG of 100% compared to O1 because of the significantly higher BMI and COI1n-4n values in O2 that were associated with more pronounced abdominal obesity and highly significantly positive correlation with BMI.Conclusions: DXA cut-off point values of indexes COI1m-4m and COI1n-4n were established as diagnostic indexes and criteria useful in discovering extreme abdominal and normal BFD. COI1m CP value of 0.55 was discovered as a diagnostic criterion of extreme abdominal obesity and COI2n of 0.38 as a diagnostic criterion of normal BFD that excluded abdominal obesity. The other indexes COI1m-4m and COI1n-4n CP values had also high DG in discovering abdominal and normal body fat distribution.

scholarly journals New DXA Diagnostic Indexes of Abdominal Obesity

PRILOZI ◽  
2021 ◽  
Vol 42 (2) ◽  
pp. 37-50
Author(s):  
Slavica Shubeska Stratrova ◽  
Sasha Jovanovska Mishevska ◽  
Ljudmila Efremovska ◽  
Iskra Bitoska ◽  
Dejan Spasovski
Keyword(s):  
Body Fat ◽  
Abdominal Obesity ◽  
Fat Mass ◽  
Fat Distribution ◽  
Dual Energy ◽  
X Rays ◽  
Obese Women ◽  
Tissue Mass ◽  
Regional Body Fat ◽  
Total Tissue

Abstract Aim: Cushing’s syndrome (CS) is associated with weight gain and extreme central, visceral, abdominal obesity which is confirmed with dual-energy X-rays absorptiometric (DXA) diagnostic cut-off point (CP) values of central obesity indexes (COI), determined as an android to gynoid tissue and fat mass ratios. These best differentiate CS from non-CS obese women matched with CS according to their age and BMI. The aim of this study was to determine the CP values of new DXA indexes of central, abdominal obesity as a ratio of android and trunk to legs as well as trunk and legs to total tissue and fat mass that best differentiate CS and matched non-CS obese women in order to confirm central abdominal obesity, and to determine their normal CP values that best differentiate healthy non-obese women from CS and non-CS obese women, and to exclude abdominal obesity completely. Material and Methods: DXA indexes of abdominal obesity, calculated as а ratio of regional body fat and tissue mass compartments android to legs (A/L), trunk to legs (Tr/L), trunk to total (Tr/To) and legs to total (L/To) values were determined among 4 groups. Each group consisted of 18 women: 1st group of CS, 2nd group of obese women (O1) not different according to their age and BMI from CS, 3rd group of obese women (O2) with higher BMI of 35 ± 1.2 kg and a 4th group of non-obese, healthy women (C) with a normal BMI. Diagnostic accuracy (DG) of CP values of DXA indexes of abdominal obesity and indexes of normal body fat distribution (BFD) were determined. Results: A/L, Tr/L, Tr/To, and L/To DXA indexes were significantly different between CS and O1 as well as between non-CS women O2 compared to O1 and C. These indexes had a highly significant correlation among each other and also in relation to their BMI (p < 0.0001). A/L-Tm CP value of 0.3 best differentiated the CS from group O1, with the highest DG of 100 % and an A/L-Fm CP value of 0.26 differentiated them with a DG of 94.44% and sensitivity of 100 %. An A/L-Tn CP value of 0.23 and an A/L-Fn CP value of 0.25 best differentiated CS and C as well as O2 and C for the highest DG of 100 %. Conclusions: DXA indexes A/L, Tr/L, Tr/To and L/To values were significantly different among the four groups. These values correlated significantly among them and with their BMI in non-CS groups, thus confirming a BMI increase association with a more pronounced abdominal BFD. An A/L-Tm CP value of 0.3 and an A/L-Fm CP value of 0.26 were discovered as the best DXA diagnostic indexes of extreme abdominal obesity in CS and these could also be used in discovering abdominal BFD in non-CS obese women with metabolic syndrome (MS). An A/L-Tn CP value of 0.23 and an A/L-Fn CP value of 0.25 were discovered as the best DXA diagnostic indexes of normal BFD which completely excluded abdominal obesity.

The relationship between coronary atherosclerosis and body fat distribution measured using dual energy X-ray absorptiometry

2016 ◽  
Vol 248 ◽  
pp. 190-195 ◽  
Author(s):  
Se-Jun Park ◽  
Hyoung-Mo Yang ◽  
Kyoung-Woo Seo ◽  
So-Yeon Choi ◽  
Byoung-Joo Choi ◽  
...  
Keyword(s):  
Body Fat ◽  
Coronary Atherosclerosis ◽  
Fat Distribution ◽  
Dual Energy ◽  
Body Fat Distribution ◽  
X Ray ◽  
The Relationship

scholarly journals Comparison of gross body fat-water magnetic resonance imaging at 3 Tesla to dual-energy X-ray absorptiometry in obese women

Obesity ◽  
2013 ◽  
Vol 21 (4) ◽  
pp. 765-774 ◽  
Author(s):  
Heidi J. Silver ◽  
Kevin D. Niswender ◽  
Joel Kullberg ◽  
Johan Berglund ◽  
Lars Johansson ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Body Fat ◽  
Dual Energy ◽  
3 Tesla ◽  
Obese Women ◽  
Resonance Imaging ◽  
X Ray

THE IMPACT OF NUTRITIONAL STATUS ON BODY FAT DISTRIBUTION PATTERNS IN PRE- AND POSTMENOPAUSAL FEMALES

1998 ◽  
Vol 30 (2) ◽  
pp. 145-154 ◽  
Author(s):  
S. KIRCHENGAST ◽  
D. GRUBER ◽  
M. SATOR ◽  
W. KNOGLER ◽  
J. HUBER
Keyword(s):  
Nutritional Status ◽  
Body Fat ◽  
Menopausal Status ◽  
Distribution Patterns ◽  
Fat Distribution ◽  
Dual Energy ◽  
Lower Body ◽  
X Ray ◽  
Low Weight ◽  
The Impact

This study examines the impact of nutritional status, classified by body mass index, on sex specific fat distribution patterns dependent on menopausal status in 467 pre-, peri- or postmenopausal females. Absolute and relative amounts of upper and lower body fat were estimated by means of dual energy X-ray absorptiometry. It was found that low weight, independent of menopausal status, leads to the typical gynoid pattern of fat distribution while excess weight and obesity result in the android pattern of distribution in pre- and postmenopausal women.

Relationship between body fat distribution and coronary atherosclerosis assessed by dual energy X-ray absorptiometry

1994 ◽  
Vol 1 ◽  
pp. 274
Author(s):  
M. Hara ◽  
T. Saikawa ◽  
H. Niwa ◽  
M. Kurokawa ◽  
A. Yoshimura ◽  
...  
Keyword(s):  
Body Fat ◽  
Coronary Atherosclerosis ◽  
Fat Distribution ◽  
Dual Energy ◽  
Body Fat Distribution ◽  
X Ray

Telephone-Based Diet and Exercise Coaching and a Weight-Loss Supplement Result in Weight and Fat Loss in 120 Men and Women

2008 ◽  
Vol 23 (2) ◽  
pp. 121-129 ◽  
Author(s):  
Larry A. Tucker ◽  
Amy J. Cook ◽  
Neil R. Nokes ◽  
Troy B. Adams
Keyword(s):  
Weight Loss ◽  
Body Fat ◽  
Dual Energy ◽  
Controlled Experiment ◽  
Obese Women ◽  
Men And Women ◽  
X Ray ◽  
Diet And Exercise ◽  
Telephone Coaching ◽  
Overweight Adults

Purpose. Determine the effects of telephone-based coaching and a weight-loss supplement on the weight and body fat (BF) of overweight adults. Design. Randomized, placebo-controlled experiment with assessments at baseline, 2 months, and 4 months. Setting. Community. Subjects. Sixty overweight or obese men and 60 overweight or obese women, 25 to 60 years old. Intervention. Eleven 30-minute telephone coaching sessions were spaced throughout the study; the initial conversation lasted 60 to 90 minutes. Supplement or placebo capsules were taken daily over the 17 weeks. Measures. Weight was measured using an electronic scale, and BF was assessed using dual energy x-ray absorptiometry. Results. Subjects taking the placebo lost 1.8 + 3.3 kg of weight and 0.7 + 2.2 kg of BF, whereas supplement users lost more: 3.1 + 3.7 kg of weight (F = 4.1, P = .045) and 1.7 + 2.6 kg of BF (F = 4.4, p = .039). Participants receiving no coaching lost 1.8 + 3.3 kg of weight and 0.7 + 2.2 kg of BF, whereas adults receiving coaching lost more: 3.2 + 3.6 kg of weight (F = 4.8, p = .032) and 1.6 + 2.5 kg of BF (F = 4.2, p = .044). Adults receiving both the supplement and coaching had the greatest losses of weight and BF, suggesting an additive effect (F = 3.2, p = .026; F = 2.9, p = .039, respectively). Conclusions. Both treatments, coaching and the supplement, viewed separately and in combination, worked to help subjects lose weight and BF. Adults can be educated and motivated via telephone to change behaviors leading to weight loss, and a weight-loss supplement can be included to increase success.

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