THE IMPACT OF NUTRITIONAL STATUS ON BODY FAT DISTRIBUTION PATTERNS IN PRE- AND POSTMENOPAUSAL FEMALES

1998 ◽  
Vol 30 (2) ◽  
pp. 145-154 ◽  
Author(s):  
S. KIRCHENGAST ◽  
D. GRUBER ◽  
M. SATOR ◽  
W. KNOGLER ◽  
J. HUBER

This study examines the impact of nutritional status, classified by body mass index, on sex specific fat distribution patterns dependent on menopausal status in 467 pre-, peri- or postmenopausal females. Absolute and relative amounts of upper and lower body fat were estimated by means of dual energy X-ray absorptiometry. It was found that low weight, independent of menopausal status, leads to the typical gynoid pattern of fat distribution while excess weight and obesity result in the android pattern of distribution in pre- and postmenopausal women.

2016 ◽  
Vol 248 ◽  
pp. 190-195 ◽  
Author(s):  
Se-Jun Park ◽  
Hyoung-Mo Yang ◽  
Kyoung-Woo Seo ◽  
So-Yeon Choi ◽  
Byoung-Joo Choi ◽  
...  

1994 ◽  
Vol 1 ◽  
pp. 274
Author(s):  
M. Hara ◽  
T. Saikawa ◽  
H. Niwa ◽  
M. Kurokawa ◽  
A. Yoshimura ◽  
...  

2019 ◽  
Vol 400 (9) ◽  
pp. 1157-1162 ◽  
Author(s):  
Ulrika Wilhelmsson ◽  
Pia Stillemark-Billton ◽  
Jan Borén ◽  
Milos Pekny

Abstract Intermediate filaments (nanofilaments) have many functions, especially in response to cellular stress. Mice lacking vimentin (Vim−/−) display phenotypes reflecting reduced levels of cell activation and ability to counteract stress, for example, decreased reactivity of astrocytes after neurotrauma, decreased migration of astrocytes and fibroblasts, attenuated inflammation and fibrosis in lung injury, delayed wound healing, impaired vascular adaptation to nephrectomy, impaired transendothelial migration of lymphocytes and attenuated atherosclerosis. To address the role of vimentin in fat accumulation, we assessed the body weight and fat by dual-energy X-ray absorptiometry (DEXA) in Vim−/− and matched wildtype (WT) mice. While the weight of 1.5-month-old Vim−/− and WT mice was comparable, Vim−/− mice showed decreased body weight at 3.5, 5.5 and 8.5 months (males by 19–22%, females by 18–29%). At 8.5 months, Vim−/− males and females had less body fat compared to WT mice (a decrease by 24%, p < 0.05, and 33%, p < 0.0001, respectively). The body mass index in 8.5 months old Vim−/− mice was lower in males (6.8 vs. 7.8, p < 0.005) and females (6.0 vs. 7.7, p < 0.0001) despite the slightly lower body length of Vim−/− mice. Increased mortality was observed in adult Vim−/− males. We conclude that vimentin is required for the normal accumulation of body fat.


PRILOZI ◽  
2020 ◽  
Vol 41 (3) ◽  
pp. 13-21
Author(s):  
Slavica Shubeska Stratrova ◽  
Sasha Jovanovska Mishevska ◽  
Iskra Bitoska ◽  
Irena Kafedziska

AbstractAim: The aim of this study was to develop quantiative criteria for defining visceral obesity and to establish dual-energy X-ray absorptiometric (DXA) diagnostic cut-off points (CP) for normal and abnormal values of the central obesity indexes (COI) that best differentiate extreme visceral obesity in Cushing’s syndrome (CS) from non CS obese and non obese women.Material and Methods: COI1–4 values calculated as a ratio of android to gynoid tissue mass, fat mass and their % were determined in 4 groups, each consisting of 18 women: 1st group of CS, 2nd group of obese women (O1) not different according to their age and BMI from CS, 3rd group of obese women (O2) with BMI of 35 ± 1.2 kg and 4th group of non obese healthy women (C) with normal BMI. Diagnostic accuracy (DG) of CP values of COI1m-4m indexes of abdominal obesity and CP values of COI1n-4n indexes of normal body fat distribution (BFD) was determined.Results: COI1-4 indexes values were highly significantly different among the 4 examined groups and were significantly highest in CS patients and lowest in group C (p < 0.0001). COI1m-4m CP values differentiated extreme visceral, abdominal obesity in CS with highest DG as well as COI1n-4n CP values differentiated normal BFD in group C. COI1m CP of 0.55 best differentiated CS from O1 for DG of 100%. COI2n of 0.38 best differentiated C from CS and O2 for highest DG of 100% compared to O1 because of the significantly higher BMI and COI1n-4n values in O2 that were associated with more pronounced abdominal obesity and highly significantly positive correlation with BMI.Conclusions: DXA cut-off point values of indexes COI1m-4m and COI1n-4n were established as diagnostic indexes and criteria useful in discovering extreme abdominal and normal BFD. COI1m CP value of 0.55 was discovered as a diagnostic criterion of extreme abdominal obesity and COI2n of 0.38 as a diagnostic criterion of normal BFD that excluded abdominal obesity. The other indexes COI1m-4m and COI1n-4n CP values had also high DG in discovering abdominal and normal body fat distribution.


Sign in / Sign up

Export Citation Format

Share Document