scholarly journals School and Education as a Part of Public Administration in the Perspective of a Smart Organisation – Selected Attributes

2020 ◽  
Vol 9 (2) ◽  
pp. 94-107
Author(s):  
Renata Raszewska-Skałecka
Keyword(s):  
Public Administration ◽  
State Of The Art ◽  
Structure And Function ◽  
Future Generations ◽  
Educational Services ◽  
Knowledge Based ◽  
Technological Educational ◽  
Smart Education ◽  
And Function

AbstractThe study is aimed at emphasising the selected aspects of smart education with regard to the school perceived as an intelligent knowledge-based organisation challenged by state-of-the-art civilisational and technological educational solutions. The study focuses on school and education with respect to the structure and function of public administration perceived as an intelligent organisation. School and educational services will determine and influence future generations of public administration staff. Their brainpower as well intellectual resources (knowledge, skills and experience) will serve the welfare of the society. Highly intelligent administration may win the respect for the organisation itself and for its services rendered to the society.

State-of-the-Art Neural Networks Applications in Biology

2013 ◽  
Vol 2 (4) ◽  
pp. 63-85 ◽  
Author(s):  
Arianna Filntisi ◽  
Nikitas Papangelopoulos ◽  
Elena Bencurova ◽  
Ioannis Kasampalidis ◽  
George Matsopoulos ◽  
...  
Keyword(s):  
Neural Networks ◽  
Game Theory ◽  
State Of The Art ◽  
Disease Diagnosis ◽  
General Term ◽  
Structure And Function ◽  
Computational Method ◽  
Processing Abilities ◽  
Central Nervous Systems ◽  
And Function

Artificial neural networks (ANNs) are a well-established computational method inspired by the structure and function of biological central nervous systems. Since their conception, ANNs have been utilized in a vast variety of applications due to their impressive information processing abilities. A vibrant field, ANNs have been utilized in bioinformatics, a general term for describing the combination of informatics, biology and medicine. This article is an effort to investigate recent advances in the area of bioinformatical applications of ANNs, with emphasis in disease diagnosis, genetics, proteomics, and chemoinformatics. The combination of neural networks and game theory in some of these application is also discussed.

Choosing a reasoning style for knowledge based system: lessons from supporting a help desk

1993 ◽  
Vol 8 (3) ◽  
pp. 201-222 ◽  
Author(s):  
Andrew M. Dearden ◽  
Derek G. Bridge
Keyword(s):  
Structure And Function ◽  
Domain Model ◽  
Explicit Model ◽  
Help Desk ◽  
Knowledge Based ◽  
Deep Model ◽  
Trade Offs ◽  
Reasoning Style ◽  
And Function ◽  
Styles Of Reasoning

AbstractIn this paper, we present two broad styles of KBS reasoner: those based primarily on some general, explicit model of the knowledge of the domain (whether that model be expressed by heuristic rules or by a deep model of structure and function), which we term domain model-based reasoners; and those based primarily on a set of examples of events in the domain, which we term example-based reasoners (EBR), of which case-based reasoners are a subset. The aim of this paper is to guide developers in considering the trade-offs between these different styles of reasoning. We believe that this cannot be done in general, but may be possible for specific domains. Thus, the paper provides an example analysis of the usefulness of these reasoning styles. We assess the suitability of these styles against a series of requirements which we have identified that KBSs must fulfil if they are to support help desk operations. We conclude that EBR systems are more likely to meet those requirements (the analysis draws on our earlier work in Bridge & Dearden, 1992).

scholarly journals Cell and tissue engineering for liver disease

2014 ◽  
Vol 6 (245) ◽  
pp. 245sr2-245sr2 ◽  
Author(s):  
Sangeeta N. Bhatia ◽  
Gregory H. Underhill ◽  
Kenneth S. Zaret ◽  
Ira J. Fox
Keyword(s):  
Tissue Engineering ◽  
Stem Cell ◽  
Liver Disease ◽  
Liver Failure ◽  
Cell Biology ◽  
State Of The Art ◽  
Structure And Function ◽  
Stem Cell Biology ◽  
And Function

Despite the tremendous hurdles presented by the complexity of the liver’s structure and function, advances in liver physiology, stem cell biology and reprogramming, and the engineering of tissues and devices are accelerating the development of cell-based therapies for treating liver disease and liver failure. This State of the Art Review discusses both the near- and long-term prospects for such cell-based therapies and the unique challenges for clinical translation.

scholarly journals Adipose-Derived Mesenchymal Cells for Bone Regereneration: State of the Art

2013 ◽  
Vol 2013 ◽  
pp. 1-11 ◽  
Author(s):  
Marta Barba ◽  
Claudia Cicione ◽  
Camilla Bernardini ◽  
Fabrizio Michetti ◽  
Wanda Lattanzi
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Tissue Regeneration ◽  
Biomedical Applications ◽  
State Of The Art ◽  
Biological Properties ◽  
Clinical Applications ◽  
Structure And Function ◽  
Tissue Reconstruction ◽  
And Function

Adipose tissue represents a hot topic in regenerative medicine because of the tissue source abundance, the relatively easy retrieval, and the inherent biological properties of mesenchymal stem cells residing in its stroma. Adipose-derived mesenchymal stem cells (ASCs) are indeed multipotent somatic stem cells exhibiting growth kinetics and plasticity, proved to induce efficient tissue regeneration in several biomedical applications. A defined consensus for their isolation, classification, and characterization has been very recently achieved. In particular, bone tissue reconstruction and regeneration based on ASCs has emerged as a promising approach to restore structure and function of bone compromised by injury or disease. ASCs have been used in combination with osteoinductive biomaterial and/or osteogenic molecules, in either static or dynamic culture systems, to improve bone regeneration in several animal models. To date, few clinical trials on ASC-based bone reconstruction have been concluded and proved effective. The aim of this review is to dissect the state of the art on ASC use in bone regenerative applications in the attempt to provide a comprehensive coverage of the topics, from the basic laboratory to recent clinical applications.

scholarly journals A Bittersweet Computational Journey among Glycosaminoglycans

Biomolecules ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 739
Author(s):  
Giulia Paiardi ◽  
Maria Milanesi ◽  
Rebecca C. Wade ◽  
Pasqualina D’Ursi ◽  
Marco Rusnati
Keyword(s):  
Core Protein ◽  
State Of The Art ◽  
Structural Diversity ◽  
Experimental Models ◽  
Substantial Improvement ◽  
Structure And Function ◽  
Computational Approaches ◽  
Free Molecules ◽  
Dynamics Simulations ◽  
And Function

Glycosaminoglycans (GAGs) are linear polysaccharides. In proteoglycans (PGs), they are attached to a core protein. GAGs and PGs can be found as free molecules, associated with the extracellular matrix or expressed on the cell membrane. They play a role in the regulation of a wide array of physiological and pathological processes by binding to different proteins, thus modulating their structure and function, and their concentration and availability in the microenvironment. Unfortunately, the enormous structural diversity of GAGs/PGs has hampered the development of dedicated analytical technologies and experimental models. Similarly, computational approaches (in particular, molecular modeling, docking and dynamics simulations) have not been fully exploited in glycobiology, despite their potential to demystify the complexity of GAGs/PGs at a structural and functional level. Here, we review the state-of-the art of computational approaches to studying GAGs/PGs with the aim of pointing out the “bitter” and “sweet” aspects of this field of research. Furthermore, we attempt to bridge the gap between bioinformatics and glycobiology, which have so far been kept apart by conceptual and technical differences. For this purpose, we provide computational scientists and glycobiologists with the fundamentals of these two fields of research, with the aim of creating opportunities for their combined exploitation, and thereby contributing to a substantial improvement in scientific knowledge.

scholarly journals A EVOLUÇÃO E CONSOLIDAÇÃO DA ATIVIDADE TURÍSTICA NO TERRITÓRIO DE BARREIRINHAS – MA

2020 ◽  
Vol 5 (17) ◽  
pp. 11073
Author(s):  
Flávio Ataide Júnior ◽  
Edenilson Dutra de Moura ◽  
Patrícia Costa Ataide
Keyword(s):  
Public Administration ◽  
Structure And Function ◽  
Public And Private ◽  
Private Investments ◽  
Diachronic Study ◽  
Tourism Activity ◽  
Descriptive Approach ◽  
Basic Infrastructure ◽  
And Function ◽  
The City

THE EVOLUTION AND CONSOLIDATION OF TOURISM ACTIVITY IN BARREIRINHAS TERRITORY – MALA EVOLUCIÓN Y CONSOLIDACIÓN DE LA ACTIVIDAD TURÍSTICA EN EL TERRITORIO DE BARREIRINHAS – MARESUMOA atividade turística é marcada por um dinamismo econômico, cultural, social, político e ambiental e suas modificações decorrem do processo gerado por novos comportamentos e equipamentos existentes nos seus territórios. Assim, este artigo tem como objetivo compreender o desenvolvimento do turismo em Barreirinhas (MA) ao longo do tempo, destacando os principais momentos que marcaram a consolidação da atividade no município. O procedimento metodológico adotado na pesquisa é um estudo diacrônico do espaço com uma abordagem qualitativa e descritiva. Destaca-se ainda a revisão da literatura em diferentes contextos analíticos, mas, ressalta-se neste trabalho a valorização das categorias do método geográfico (processo, forma, estrutura e função), proposta por Milton Santos (1985), além de levantamentos de dados secundários nos instrumentos de planejamento turístico da esfera da administração pública municipal e também estadual, buscando explicar as modificações no território barreirinhense atreladas à estruturação e consolidação da atividade turística. Quanto aos resultados, o presente artigo provoca reflexões sobre diferentes temporalidades e modificações territoriais na área de estudo e traz questionamentos importantes sobre as melhorias da infraestrutura básica e turística geradas a partir de investimentos públicos e privados na cidade de Barreirinhas – Maranhão.Palavras-chave: Atividade turística. Dinâmicas territoriais. Barreirinhas – MA.ABSTRACTThe tourist activity is marked by economic, cultural, social, political and environmental dynamism and its modifications result from the process generated by new behaviors and equipment existing in its territories. Thus, this article aims to understand the development of tourism in Barreirinhas (MA) over time, highlighting the main moments that marked the consolidation of activity in the municipality. The methodological procedure adopted in the research is a diachronic study of space with a qualitative and descriptive approach. It is also worth mentioning the literature review in different analytical contexts, but it is worth highlighting in this work the valuation of the categories of the geographical method (process, form, structure and function) proposed by Milton Santos (1985), besides data surveys secondary in the instruments of tourist planning of the sphere of the municipal and also state public administration, trying to explain the modifications in the Barranquilla territory linked to the structuring and consolidation of the tourist activity. Regarding the results, this article provokes reflections on different temporalities and territorial modifications in the study area and brings important questions about the improvements of the basic infrastructure and tourism generated from public and private investments in the city of Barreirinhas - Maranhão.Keywords: Tourism activity. Territorial dynamics. Barreirinhas – MA.RESUMENLa actividad turística está marcada por un dinamismo económico, cultural, social, político y ambiental, y sus modificaciones resultan del proceso generado por los nuevos comportamientos y equipamiento existente en sus territorios. Así, este artículo pretende comprender el desarrollo del turismo en Barreirinhas (MA) a lo largo del tiempo, destacando los principales momentos que marcaron la consolidación de la actividad en el municipio. El procedimiento metodológico adoptado en la investigación es un estudio diacrónico del espacio con un enfoque cualitativo y descriptivo. También hay una revisión de la literatura en diferentes contextos analíticos, pero se destaca en este documento la apreciación de las categorías del método geográfico (proceso, forma, estructura y función), propuesto por Milton Santos (1985), y de la recopilación de datos secundarios provenientes de los instrumentos de planificación turística de la administración pública municipal y estatal, que buscan explicar los cambios en el territorio de Barreirinhense relacionados con la estructuración y consolidación de la actividad turística. En cuanto a los resultados, el presente artículo suscita reflexiones sobre diferentes temporalidades y modificaciones territoriales en el área de estudio y plantea importantes interrogantes sobre las mejoras en la infraestructura básica y turística generada a partir de inversiones públicas y privadas en la ciudad de Barreirinhas - Maranhão.Palabras clave: Actividad turística. Dinámicas territoriales. Barreirinhas – MA.

scholarly journals Radiation-Induced Vascular Disease—A State-of-the-Art Review

2021 ◽  
Vol 8 ◽  
Author(s):  
Eric H. Yang ◽  
Konstantinos Marmagkiolis ◽  
Dinu V. Balanescu ◽  
Abdul Hakeem ◽  
Teodora Donisan ◽  
...  
Keyword(s):  
Vascular Disease ◽  
State Of The Art ◽  
Structure And Function ◽  
Steady Increase ◽  
Published Data ◽  
Cardiac Structure ◽  
The Us ◽  
Radiation Induced ◽  
Cardiac Structure And Function ◽  
And Function

Since the 1990s, there has been a steady increase in the number of cancer survivors to an estimated 17 million in 2019 in the US alone. Radiation therapy today is applied to a variety of malignancies and over 50% of cancer patients. The effects of ionizing radiation on cardiac structure and function, so-called radiation-induced heart disease (RIHD), have been extensively studied. We review the available published data on the mechanisms and manifestations of RIHD, with a focus on vascular disease, as well as proposed strategies for its prevention, screening, diagnosis, and management.

scholarly journals Ultrasonography of the Anterolateral Ligament of the Knee Joint. The State of the Art and the Perspectives

2021 ◽  
Vol 1 (56) ◽  
pp. 38-42
Author(s):  
Oleksandr Kostrub ◽  
◽  
Viktor Kotiuk ◽  
Roman Luchko ◽  
Roman Blonsky ◽  
...  
Keyword(s):  
Anterior Cruciate Ligament ◽  
Knee Joint ◽  
State Of The Art ◽  
Cruciate Ligament ◽  
Lower Leg ◽  
Structure And Function ◽  
Anterolateral Ligament ◽  
Key Words Ultrasonography ◽  
Anterior Cruciate ◽  
And Function

The anterolateral ligament of the knee is an important stabilizer of the knee in relation to internal rotation of the lower leg. Ultrasonographic examination of the anterolateral ligament of the knee joint is a simple and affordable method for its study, it allows to evaluate the femoral and tibial portions, has prospects for improving and improving the understanding of its function. The indication for its implementation is suspicion or confirmed damage to the anterior cruciate ligament. Ultrasonographic studies of the anterolateral ligament are not only important from the perspective of diagnosing its damage, but have already supplemented our understanding of its structure and function. Key words: ultrasonography, anterolateral ligament, knee joint.

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