scholarly journals ADAPTASI BIOMOLEKULER HIPERTROPI JARINGAN OTOT RANGKA PADA LATIHAN BEBAN DAN MANFAATNYA PADA SINDROMA METABOLIK

2019 ◽  
Author(s):  
I Putu Adiartha Griadhi
Keyword(s):  
Metabolic Syndrome ◽  
Muscle Mass ◽  
Human Body ◽  
Theoretical Foundation ◽  
Weight Training ◽  
Metabolic Function ◽  
Repair Pathway ◽  
Catabolic Pathway ◽  
The Metabolic Syndrome ◽  
Hormone Sensitive

ABSTRACTWeight training is one of the exercises needed to achieve physical fitness. This exercise can increase muscle mass and metabolic function of the muscles so that it becomes an important exercise in the condition of the metabolic syndrome. Muscle is the largest hormone-sensitive tissue in the human body, this tissue consumes a lot of oxygen and consumes most of the glucose through the mediation of insulin. Weight training results in hypertrophy or increase in muscle mass and hyperplasia or increase in the number of muscle cells. Various biomolecular mechanisms can explain the hypertrophy and hyperplasia processes including the anabolic mTOR pathway, the catabolic pathway myostatin - Smad and the repair pathway by Satellite Cells. Understanding of the biomolecular process can provide a theoretical foundation in developing a weight training program so that the exercise becomes effective and safe.Keyword : weight training, metabolic syndrom, muscle hipertrophy

scholarly journals Effect of menopausal hormone therapy on components of the metabolic syndrome

2016 ◽  
Vol 11 (1) ◽  
pp. 33-43 ◽  
Author(s):  
Dragana Lovre ◽  
Sarah H. Lindsey ◽  
Franck Mauvais-Jarvis
Keyword(s):  
Metabolic Syndrome ◽  
Hormone Therapy ◽  
Visceral Obesity ◽  
Menopausal Hormone Therapy ◽  
World Population ◽  
Metabolic Function ◽  
Metabolic Dysfunction ◽  
The Metabolic Syndrome ◽  
The World

The world population is aging, and women will spend an increasing share of their lives in a postmenopausal state that predisposes to metabolic dysfunction. Thus, the prevalence of metabolic syndrome (MetS) in women is likely to increase dramatically. This article summarizes the effects of menopause in predisposing to components of MetS including visceral obesity, dyslipidemia, type 2 diabetes (T2D) and hypertension (HTN). We also summarize the effects of menopausal hormone therapy (MHT) in reversing these metabolic alterations and discuss therapeutic advances of novel menopausal treatment on metabolic function.

Associations of low muscle mass and the metabolic syndrome in Caucasian and Asian middle-aged and older adults

2015 ◽  
Vol 20 (3) ◽  
pp. 248-255 ◽  
Author(s):  
D. Scott ◽  
M. S. Park ◽  
T. N. Kim ◽  
J. Y. Ryu ◽  
H. C. Hong ◽  
...  
Keyword(s):  
Older Adults ◽  
Metabolic Syndrome ◽  
Muscle Mass ◽  
Middle Aged ◽  
The Metabolic Syndrome

Inverse associations between muscle mass, strength, and the metabolic syndrome

Metabolism ◽  
2009 ◽  
Vol 58 (7) ◽  
pp. 1013-1022 ◽  
Author(s):  
Evan Atlantis ◽  
Sean A. Martin ◽  
Matthew T. Haren ◽  
Anne W. Taylor ◽  
Gary A. Wittert
Keyword(s):  
Metabolic Syndrome ◽  
Muscle Mass ◽  
The Metabolic Syndrome

scholarly journals Muscle mass to visceral fat ratio is an important predictor of the metabolic syndrome in college students

2018 ◽  
Vol 121 (3) ◽  
pp. 330-339 ◽  
Author(s):  
Robinson Ramírez-Vélez ◽  
Antonio Garcia-Hermoso ◽  
Daniel Humberto Prieto-Benavides ◽  
Jorge Enrique Correa-Bautista ◽  
Aura Cristina Quino-Ávila ◽  
...  
Keyword(s):  
Risk Factors ◽  
College Students ◽  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Young Adults ◽  
Muscle Mass ◽  
Visceral Fat ◽  
Biochemical Parameters ◽  
Cardiometabolic Risk ◽  
The Metabolic Syndrome

AbstractThis study aimed to evaluate the associations between the muscle mass to visceral fat (MVF) ratio and cardiometabolic risk factors in a large population of college students in Colombia and to propose cut-off points of this index for the metabolic syndrome (MetS). A total of 1464 young adults recruited from the FUPRECOL (Asociación de la Fuerza Prensil con Manifestaciones Tempranas de Riesgo Cardiovascular en Jóvenes y Adultos Colombianos) study were categorised into four groups based on their MVF ratio. Muscle mass and visceral fat level of the participants were measured using a bioelectrical impedance analysis. Cardiometabolic risk factors including lifestyle characteristics, anthropometry, blood pressure and biochemical parameters were assessed. The prevalence of moderate to severe obesity, hypertension and the MetS was higher in subjects in quartile (Q)1 (lower MVF ratio) (P <0·001). ANCOVA revealed that the subjects in Q1 had higher cardiometabolic disturbances, including altered anthropometry, blood pressure, muscle strength and biochemical parameters after adjusting for age and sex compared with young adults in higher MVF ratio quartiles (P <0·001). Muscular mass and physical activity levels were significantly lower in subjects with a lower MVF ratio (P <0·001). The receiver operating characteristic curve analyses indicated that in men the best MVF ratio cut-off point for detecting the MetS was 18·0 (AUC 0·83, sensitivity 78 % and specificity 77 %) and for women, the MVF ratio cut-off point was 13·7 (AUC 0·85, sensitivity 76 % and specificity 87 %). A lower MVF ratio is associated with a higher risk cardiometabolic profile in early adulthood, supporting that the MVF ratio could be used as a complementary screening tool that may help clinicians identify young adults at high cardiometabolic risk.

scholarly journals Genetics of the metabolic syndrome

2000 ◽  
Vol 83 (S1) ◽  
pp. S39-S48 ◽  
Author(s):  
Leif Groop
Keyword(s):  
Insulin Resistance ◽  
Metabolic Syndrome ◽  
Glycogen Synthase ◽  
Insulin Resistance Syndrome ◽  
Hormone Sensitive Lipase ◽  
Common Denominator ◽  
The Metabolic Syndrome ◽  
Genome Wide ◽  
Hormone Sensitive ◽  
Obesity Hypertension

The clustering of cardiovascular risk factors such as abdominal obesity, hypertension, dyslipidaemia and glucose intolerance in the same persons has been called the metabolic or insulin-resistance syndrome. In 1998 WHO proposed a unifying definition for the syndrome and chose to call it the metabolic syndrome rather than the insulin-resistance syndrome. Although insulin resistance has been considered as a common denominator for the different components of the syndrome, there is still debate as to whether it is pathogenically involved in all of the different components of the syndrome. Clustering of the syndrome in families suggests a genetic component. It is plausible that so-called thrifty genes, which have ensured optimal storage of energy during periods of fasting, could contribute to the phenotype of the metabolic syndrome. Common variants in a number of candidate genes influencing fat and glucose metabolism can probably, together with environmental triggers, increase susceptibility to the syndrome. Among these, the genes for β3-adrenergic receptor, hormone-sensitive lipase, lipoprotein lipase, IRS-1, PC-1, skeletal muscle glycogen synthase, etc. appear to increase the risk of the metabolic syndrome. In addition, novel genes may be identified by genome-wide searches.

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