scholarly journals Endothelial shear rate, local and regional vascular stiffness in patients in different stages of atherogenesis

2016 ◽  
Vol 15 (3) ◽  
pp. 50-56
Author(s):  
V. V. Genkel ◽  
A. O. Salachenko ◽  
O. A. Alekseeva ◽  
I. I. Shaposhnik

Introduction and purpose. Endothelial cells are subjected to biomechanical stress produced by the bloodstream and tunica media of the vessel. Vascular stiffness and endothelial shear stress have cooperative effects on the endothelial structure and function. However, the relationship of shear stress and arterial stiffness is still poorly understood. The purpose of the study was to assess the relationship of endothelial shear rate and both local and regional vascular stiffness in patients at different stages of the development of atherosclerosis. Methods. The study included 60 patients, 33 men and 27 women. The average age of patients was 54.8±11.7 years. Regional arterial stiffness was assessed by measurement of the pulse wave velocity in the arteries of elastic and muscular types. Local stiffness of the carotid arteries was characterized by Peterson elastic modulus, Young's modulus, stiffness index β, the deformation of the common carotid artery. Endothelial shear rate was measured at the site of the common carotid artery. Results. Average values of carotid endothelial shear rate were equal to 433±127 s-1. Reduced endothelial shear rate in the carotid arteries was associated with an increased Peterson modulus (r = -0.289; p = 0.025) and the stiffness index β (r = -0.280; p = 0.037), and moreover - with decreasing vascular distensibility (r = 0.288; p = 0.026) and deformation (r = 0.296; p = 0.024). Assessment of the relationship between endothelial shear rate and regional vascular stiffness showed weak statistically significant negative correlation of shear rate and PWVcf (r = -0.367; p = 0.014). Conclusion. In study subjects endothelial shear rate reduction in the area of the common carotid artery was associated with an increased Peterson modulus, stiffness index β, decreasing deformation of carotid arteries and increase in aortic stiffness.

2000 ◽  
Vol 122 (4) ◽  
pp. 590-591 ◽  
Author(s):  
Natalija Lučev ◽  
Dragica Bobinac ◽  
Ivana Marić ◽  
Ivan Drešćik

The variations of the common carotid artery, as well as of the external and internal carotid arteries, are described. During anatomic dissection on adult cadavers, we investigated the variability of appearance of 40 carotid arterial systems. Special consideration was given to the topographic relations such as the level of the bifurcation of the common carotid artery, the relationship between the external and internal carotid arteries, and the origin of the great collateral branches. Special attention was paid to the origin of the superior thyroid artery. In this article the practical importance of these variations is stressed.


1995 ◽  
Vol 109 (9) ◽  
pp. 889-891 ◽  
Author(s):  
Saichiro Tanaka ◽  
Yasuyuki Kimura ◽  
Mitsuru Furukawa

AbstractPseudoaneurysms of the extracranial carotid arteries are rarely seen following irradiation for cancers of the head and neck. We present a patient with a pseudoaneurysm of the common carotid artery following a radical neck dissection and irradiation for thyroid carcinoma 20 years earlier. Following oesophagoscopical examination, a pseudoaneurysm of the right common carotid artery ruptured into the piriform sinus. The common carotid artery was embolized with multiple coils and the bleeding was halted. The relationship between the carotid artery aneurysm and irradiation, and the treatment of carotid artery aneurysm, is discussed.


1997 ◽  
Vol 23 (4) ◽  
pp. 583-590 ◽  
Author(s):  
Steven K. Samijo ◽  
Jean M. Willigers ◽  
Peter J. Brands ◽  
Richard Barkhuysen ◽  
Robert S. Reneman ◽  
...  

2007 ◽  
Vol 8 (1) ◽  
pp. 136 ◽  
Author(s):  
E. Chytilova ◽  
J. Malik ◽  
Z. Kasalova ◽  
R. Dolezalova ◽  
J. Housova ◽  
...  

2019 ◽  
Vol 2019 ◽  
pp. 1-15 ◽  
Author(s):  
L. Vasović ◽  
M. Trandafilović ◽  
S. Vlajković

In an attempt to describe the morphofunctional consequences of uni- and bilateral aplasia of the common carotid artery (CCA), which is usually a vascular source of the external carotid (ECA) and internal carotid (ICA) arteries, we investigated online databases of anatomical and clinical papers published from the 18th century to the present day. We found 87 recorded cases of uni- and bilateral CCA aplasia in subjects from the first hours to the eighth decade of life, which had been discovered in 14 (known) countries. Four crucial parameters were described: the embryology of the carotid arteries, morphophysiology of the carotid arteries, CCA aplasia, and unilateral versus bilateral CCA aplasia, including history, general data, diagnosing, vascular sources, caliber, course of the separated ECA and ICA, associated vascular variants, and pathological disorders. To complete the knowledge of the morphofunctional consequences of the absence of some artery of the carotid system, and risking the possibility of repeating some words, as “carotid artery”, or “carotid aplasia” and the headings from our previous article about bilateral ICA absence, this review is the first in the literature that recorded all cases of the CCA aplasia published and/or cited for the past 233 years. Main characteristic of the CCA absence is its association with 21 different diseases, among which the aneurysms were in 13.69% of cases, and 17.80% of cases were without pathology.


2009 ◽  
Vol 66 ◽  
pp. 139-142 ◽  
Author(s):  
Ji Jun Qian ◽  
Ai Ping Chen ◽  
Zhong Xin Liu ◽  
Chun Zhong Li

The rheological properties of carbon black gel ink were investigated by measurement the relationship between shear stress and shear rate. The fitting to the common rheological curve of gel ink with Hersegel-Bulkley equation was introduced. And the rheological parameters used to characterize the writing properties of gel ink were proposed. The results indicated that the gel ink system possessed strong shear-thinning ability. And the writing performance of the gel ink could be characterized with rheological parameters comprehensively.


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