scholarly journals Transportation of Food by Cold Chain Methods one of the Cause of Reoccurrence Covid-19 Infection during its Pandemic

2021 ◽  
Vol 9 (12) ◽  
pp. 2376-2378
Author(s):  
Mesut Selamoğlu ◽  
Ali Raza Memon
Keyword(s):  
Acute Respiratory Distress Syndrome ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Viral Infection ◽  
Distress Syndrome ◽  
Morbidity And Mortality ◽  
Cold Chain ◽  
Corona Virus ◽  
The World ◽  
Second Wave

The Corona Virus is the pandemic all over the world. This viral infection attacked all over the world like as disaster of viral infection which causes morbidity and mortality in different regions of world like Asia, Europe, and Africa etc. The different countries control the spread and complications of covid-19 like Acute Respiratory Distress Syndrome in well manner. In second wave there was again out break of covid-19 some regions of world. Here we discuss the causes of reoccurrence and their preventive measurements from our break effects of Covid-19.

Nitric oxide and interval hypoxic training in COVID-19 rehabilitation— new research direction

2021 ◽  
pp. 30-41
Author(s):  
Tatyana Nikolaevna Tsyganova ◽  
Egor Egorov ◽  
Tamara Nikolaevna Voronina
Keyword(s):  
Nitric Oxide ◽  
Acute Respiratory Distress Syndrome ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Viral Infection ◽  
Distress Syndrome ◽  
The Body ◽  
Lung Damage ◽  
Specific Method ◽  
Hypoxic Training

COVID-19, a disease caused by the novel coronavirus SARS-CoV-2, primarily affects lung tissue and disrupts gas exchange, leading to acute respiratory distress syndrome, systemic hypoxia, and lung damage. The search for methods of prevention and rehabilitation, especially after suffering from pneumonia caused by COVID-19, is on the agenda. This article discusses the possibilities of the interval hypoxic training (IHT) method for preventing infections by initiating nitric oxide production in the body. One of the main effects of IHT is the balanced stimulation of nitric oxide (NO) secretion. Over the past two decades, there has been an increasing interest in the function of nitric oxide (NO) in the human body. Nitric oxide plays a key role in maintaining normal vascular function and regulating inflammatory processes, including those leading to lung damage and the development of acute respiratory distress syndrome (ARDS). Our immune system destroys bacteria and viruses by oxidative burst, i.e. when oxygen accumulates inside the cell. This process also involves nitric oxide, a signaling molecule that has an antibacterial and antiviral effect, as well as regulates vascular tone and affects the permeability of the cell wall. Interval hypoxytherapy enhances endogenous oxidative protection and increases the amount of nitric oxide, thus allowing the body’s cells to resist infection more effectively. Mitochondrial NOS induction and mitochondrial NO synthesis increase under the action of pathogenic factors on the cell. By modulating the activity of mtNOS and the synthesis of mitochondrial NO, it is possible to increase the resistance to hypoxic effects. Interval hypo-hyperoxic training as an effective non-specific method of increasing the body’s defenses is indispensable not only in the prevention of viral infection, but also in rehabilitation after viral pneumonia, as well as as a method that reduces the severity of viral infection in the event of infection.

scholarly journals Cannabidiol Modulates Cytokine Storm in Acute Respiratory Distress Syndrome Induced by Simulated Viral Infection Using Synthetic RNA

2020 ◽  
Vol 5 (3) ◽  
pp. 197-201 ◽  
Author(s):  
Hesam Khodadadi ◽  
Évila Lopes Salles ◽  
Abbas Jarrahi ◽  
Fairouz Chibane ◽  
Vincenzo Costigliola ◽  
...  
Keyword(s):  
Acute Respiratory Distress Syndrome ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Viral Infection ◽  
Distress Syndrome ◽  
Cytokine Storm

scholarly journals Studi Literatur: Tinjauan Pemeriksaan  Laboratorium pada Pasien COVID-19

2021 ◽  
Vol 5 (4) ◽  
pp. 242
Author(s):  
Rosdiana Mus ◽  
Thaslifa Thaslifa ◽  
Mutmainnah Abbas ◽  
Yanti Sunaidi
Keyword(s):  
Acute Respiratory Distress Syndrome ◽  
Open Access ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Distress Syndrome ◽  
Google Scholar ◽  
Pubmed Central ◽  
Corona Virus

Latar Belakang: Penyakit Corona virus 19 (COVID-19) yang disebabkan oleh SARS-COV-2 terjadi melalui droplet dengan menyerang saluran pernafasan melalui reseptor ACE2, menyebabkan pneumonia berat yaitu Acute Respiratory Distress Syndrome. Pemeriksaan laboratorium penting dalam menunjang diagnosis dan menilai prognosis penyakit COVID-19.Tujuan: Tinjauan ini menjelaskan peran diagnosis dan prognosis pengembangan COVID-19 pada tes laboratorium berdasarkan kemajuan penelitian terbaru SARS-CoV-2 yang telah dilaporkan.Metode: Penelitian bersifat studi literatur dengan menggunakan data sekunder. Sumber data penelitian berasal dari e-journal yaitu Google Scholar, Open Access, dan PubMed Central yang dilakukan skrining berdasarkan kata kunciHasil: Pemeriksaan imunoserologi menunjukan IgM dan IgG muncul secara berurutan pada hari ke 12 dan 14 setelah terinfeksi. Pemeriksaan hematologi melaporkan peningkatan jumlah neutrofil dan penurunan jumlah limfosit. NLR tinggi pada pasien yang parah. Pemeriksaan kimia klinik menunjukan penurunan albumin, peningkatan CRP, LDH, kreatinin, AST dan ALT.Kesimpulan: Pemeriksaan imunoserologi dilakukan dengan pemeriksaan sel T, sel B serta menilai kadar immunoglobin (IgM dan IgG). Parameter hematologi digunakan untuk memprediksi keparahan COVID-19, termasuk limfosit, leukosit dan neutrofil. Peningkatan neutrofil-leukosit rasio (NLR)  dapat digunakan sebagai marker untuk menilai faktor risiko COVID-19. Pada pemeriksaan kimia klinik ditemukan peningkatan kadar pada parameter fungsi hati, fungsi jantung, analisa gas darah dan penanda inflamasi.

scholarly journals Atypical facial onset Guillain-Barré syndrome following first dose of COVISHIELD vaccine

2021 ◽  
Vol 20 (3) ◽  
pp. 379-382
Author(s):  
R.V. Aravinda ◽  
◽  
Priyanka Mahendra Tater ◽  
Harsha Huliyappa ◽  
Christy Joseph Manual ◽  
...  
Keyword(s):  
Acute Respiratory Distress Syndrome ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Distress Syndrome ◽  
Guillain Barre Syndrome ◽  
Significant Morbidity ◽  
Global Pandemic ◽  
The World ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

In the midst of the global pandemic of COVID-19 and its significant morbidity and mortality reported across the world due to severe acute respiratory distress syndrome (SARS), it has always been posing a new set of complications each passing day. As we are still in the process of understanding about the complications related to COVID-19, we are encountered with complications related to immunization for COVID-19. We are reporting a case of facial onset Guillain-Barré syndrome (GBS) in the patient who received first dose of COVISHIELD vaccine a couple of weeks prior to the onset of his illness.

scholarly journals Combined effects of Tocilizumab and Remdesivir in severe COVID- 19 patient with cytokine release syndrome: A case-report (Preprint)

2021 ◽  
Author(s):  
Sabahat Ali ◽  
Sundas Khalid ◽  
Maham Afridi ◽  
Samar Akhtar ◽  
Yousef S. Khader ◽  
...  
Keyword(s):  
Acute Respiratory Distress Syndrome ◽  
Severe Acute Respiratory Syndrome ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Distress Syndrome ◽  
Virus Disease ◽  
Cytokine Release ◽  
Cytokine Release Syndrome ◽  
Treatment Regimens ◽  
Corona Virus

BACKGROUND Novel corona virus (nCoV) or Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is known to cause severe bilateral pneumonia and acute respiratory distress syndrome (ARDS) or Corona virus disease-2019 (COVID-19) in patients that can be debilitating and even fatal. With no drugs or vaccines available yet, a wide range of treatment regimens used are being repurposed. The need of the hour is to analyze various regimens available and devise a treatment plan most effective against SARS-CoV-2. OBJECTIVE Patient concerns: A 68-year-old hypertensive, diabetic male, exhibiting symptoms of cough and shortness of breath presented at the emergency department of our hospital. Diagnosis: Chest CT revealed bilateral ground glass opacities indicative of COVID-19 and the CT score of 24 indicated severe pulmonary pneumonia. He tested positive for COVID-19. METHODS Interventions: The treatment regimen included use of convalescent plasma, oxygen therapy, steroids, high dose antibiotics, broad spectrum antiviral Remdesivir, and anti-interleukin-6 monoclonal antibody/Tocilizumab at various stages of the disease. RESULTS Outcomes: Oxygen support was required at the time of admission. The patient initially developed cytokine release storm and mechanical ventilation was used to manage his condition. Supportive care and multiple treatment regimens were used to successfully recover the patient’s health. CONCLUSIONS Lessons: With a rapid increase in number of confirmed cases worldwide, COVID-19 has become a major challenge to our healthcare system. With no available vaccines currently, finding a combination of therapeutic drugs which are effective in reducing progression of disease is of utmost importance. CLINICALTRIAL Abbreviations:COVID-19=Corona virus disease 2019, nCoV=Novel corona virus (nCoV), SARS-CoV-2=Severe acute respiratory syndrome coronavirus 2, ARDS=acute respiratory distress syndrome, RT PCR= real-time polymerase chain reaction, SPO2= oxygen saturation, ICU=Intensive Care Unit, GGO=ground glass opacities, TDS=thrice daily, OD=once daily, BD= twice daily, CRS= cytokine release syndrome, CPAP=continuous positive airway pressure,FiO2= fraction of inspired oxygen, PEEP=positive end-expiratory pressure, PSV= pressure support ventilation.

scholarly journals Overview of therapeutic options in COVID-19

2021 ◽  
Vol 58 (2) ◽  
pp. 669-677
Author(s):  
Sarthak Katyal, Dr. Swarupa Chakole
Keyword(s):  
Acute Respiratory Distress Syndrome ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Distress Syndrome ◽  
Preventive Measures ◽  
Respiratory Disorder ◽  
The Novel ◽  
Disease Avoidance ◽  
The World ◽  
The City

Coronavirus is essentially a respiratory sickness brought about by a newfound rSARS-CoV-2 infection and distinguished in the city of Wuhan, China in December 2019. The emerging outbreak of Covid disease 2019 (COVID-19) brought about because ofthe severe respiratory disorder Covid 2 (SARS-CoV-2) presents a phenomenal test for medical services frameworks around the world.WHO has proclaimed this illness as a pandemic, and cautioned different nations. Like other Covids, this may create respiratory plot contaminations in the patients range from gentle to lethal ailment like pneumonia and ARDS(acute respiratory distress syndrome).The features of coronavirus and the capacity to quickly make far reaching contamination has significant ramifications, justifying vivacious disease avoidance and the preventive measures. While the affirmed quantity of the cases have outperformed 10.3 million throughout the world and keeps on developing, as the possible seriousness related to infection along  with its destructive confusions needs critical advancement of the novel restorative specialists to both forestall and cure the COVID-19 illness . In spite of the fact that antibodies and explicit medication treatments presently can't seem to be found, progressing investigation and subjective preliminaries have led to the examination of viability of the  reused medications for curing COVID-19 illness .According to the current audit, some of the medication competitors have been recommended to cure  COVID-19 will be talked about. While these incorporate enemy of the viral specialists (remdesivir ,rebetol, lopinavir-ritonavir,choloroquine, favipiravir, hydroxychloroquine, umifenovir ,oseltamivir,), immunomodulating based specialists (interferons, plasma bondings , tocilizumab), (azithromycin, corticosteroids),  along with other random specialists. With components of activity and further pharmacology based property which should be investigated, within a specific spotlight on the proof  base wellbeing with viability of a every specialist.

Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome in Adults

2013 ◽  
Vol 24 (2) ◽  
pp. 149-158 ◽  
Author(s):  
Kelly E. Williams
Keyword(s):  
Acute Respiratory Distress Syndrome ◽  
Extracorporeal Membrane Oxygenation ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Distress Syndrome ◽  
Ventilatory Support ◽  
Mortality Rates ◽  
Morbidity And Mortality ◽  
Traditional Management ◽  
Membrane Oxygenation

Despite advances in treatment, acute respiratory distress syndrome (ARDS) remains a common cause of respiratory failure requiring ventilatory support and is associated with significantly high rates of morbidity and mortality. To date, the only treatment shown to increase survival rate in patients with ARDS is the use of supportive mechanical ventilation using low tidal volumes. Extracorporeal membrane oxygenation (ECMO) is a therapy that has been used in severe cases of ARDS when patients fail to improve with traditional management. Recent literature shows varying mortality rates for the use of ECMO for ARDS; however, the literature suggests that transfer of patients to an ECMO center for treatment using specific criteria and indications may improve outcomes. Further research is needed regarding the timing of the initiation of ECMO, standardization of therapy, and which type of ECMO reduces morbidity and mortality rates in patients with ARDS.

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