scholarly journals Satisfaction of Search: Recurrent Wilms Tumor Mimicking Chest Port Granuloma on Chest Film

2020 ◽  
Vol 10 ◽  
pp. 13
Author(s):  
Nikki D. Rousslang ◽  
Elizabeth Rooks ◽  
Kara Delaney

Wilms tumor (nephroblastoma) is the most common renal malignancy of childhood and typically presents as a painless abdominal mass. The high success rates of surgery and chemotherapy make recurrence of Wilms tumor uncommon. We report the case of a 5-year-old girl who underwent radical nephrectomy and chemotherapy for a Wilms tumor, but suffered a relapse of the tumor to the lung. The metastasis was initially detected as a density on chest radiograph that was, coincidentally, in the same location as a recently explanted chest port. The diagnosis of recurrent malignancy was thus obscured by the patient’s history as well as a correlating physical examination finding of a palpable mass at the site of the previously placed chest port. Moreover, the mass was not seen on lateral view, all of which suggested an alternative diagnosis of granulation tissue versus seroma rather than recurrent Wilms tumor. A high degree of clinical suspicion was necessary on the part of the clinician and radiologist to diagnose the relapse.

2019 ◽  
Vol 12 (11) ◽  
pp. e231694 ◽  
Author(s):  
Harry Ross Powers ◽  
Mark Anthony Diaz ◽  
Julio C Mendez

A 25-year-old Filipino woman living in the USA was evaluated for a 5-month history of left eye pain and a subsequent orbital mass. Histopathological analysis of the lacrimal mass showed a mixed inflammatory process with necrotising granulomas and positive cultures for Mycobacterium tuberculosis. She was treated with antituberculosis therapy, with resolution of symptoms. Tuberculosis dacryoadenitis is extremely rare in the USA and other developed countries. It requires a high degree of clinical suspicion with special attention to the patient’s history to make the correct diagnosis. It can be treated successfully with antituberculosis therapy.


2017 ◽  
Vol 2 (1) ◽  

Introduction: Abdominal masses in the neonatal period often present a diagnostic challenge. The aim of this study was to evaluate which urological pathologies cause the formation of a neonatal mass, the diagnostic pathway and surgical outcome. Patients and methods: The medical and radiological records of 30 neonates who were admitted to the Neonatal Surgical Unit of Yorkhill Sick Children Hospital, Glasgow with an abdominal mass over a five-year period (2008-2013) were reviewed. Data collected included demographics, gestational age, radiological investigations, operative findings and complications. Result: Seventeen neonates (9 males, 8 females) were identified with an abdominal mass arising from the urological tract. Four boys were found to have posterior urethral valves while in 4 girls a duplex kidney with a ureterocele was identified. In the remaining 9 patients the palpable mass was caused by: vesicoureteric reflux (n=2), multicystic dysplastic kidney (n=2), polycistic kidney disease (n=1), ectopic kidney (n=1), pelvi-ureteric junction obstruction (PUJO) (n=1), unilocular renal cyst (n=1), PUJO and vesicoureteric junction obstruction (n=1). Nine patients required a form of urinary diversion and in two of these patients a nephrostomy was followed by a pyeloplasty, 2 required incision of ureteroceles, 1 nephrectomy, 1 partial nephrectomy, 1 STING and 1 primary valve ablation. Conclusion: Only 70% of newborns with abdominal masses were diagnosed antenatally, while 30% were detected postnatally. Posterior urethral valves remain the most common cause of a neonatal mass in a male, while duplex kidneys with ureterocele were seen in girls. Half of the patients will require a form of urinary diversion in the neonatal period. The large majority (88%) of abdominal masses of urological origin required surgical intervention.


2017 ◽  
Vol 5 (3) ◽  
pp. 110-115
Author(s):  
Bruno Rafael Kunz Bereza ◽  
Tariane Friedrich Foiato Maneti ◽  
Vitor Arce Ferreira Cathcart ◽  
Raimundo Romilton Leal do Rosário ◽  
Paula Nunes ◽  
...  

Wilms Tumor (WT) is an extremely rare neoplasia in adults. It represents 95% and 1% of all renal tumors, in adults and children respectively. Clinical symptoms are also distinct between adults and children. In adults, symptoms are usually abdominal pain and hematuria, on the other hand, pediatric patients frequently present with an asymptomatic abdominal mass. The recommended treatment for WT in adults follows protocols established for pediatric patients. Currently, the 5-year overall survival rate for adults with WT is of approximately 90%. The adoption of multimodal therapy systematized, and proposed by current protocols, allowed the results to become much more robust, with a significant improvement from less than 30% to 90%. However, recent reviews suggest a worse outcome for adults when compared to children, even when submitted to the same treatment regimen, and comparable according to histology and tumor stage.We present a case of a 26 years-old male patient, who underwent surgery to treat a solid renal mass. Pathological report demonstrated a Wilms tumor. The patiente also received adjuvant chemotherapy with dactinomycin and vincristine. After 12 months follow-up, patient has no evidence of disease.


2019 ◽  
Vol 2 (3) ◽  
pp. 65-68
Author(s):  
Sellami Sahla ◽  
◽  
Ammar Saloua ◽  
Ben Hammouda Saif ◽  
Chaari Chiraz ◽  
...  

Background: Rhabdoid tumor of the kidney is an uncommon and aggressive tumor characterized by poor outcomes. Given the rarity of this tumor, the diagnosis is still a challenge and the treatment are not well codified. Case report: A 4-month-old girl presented with abdominal mass. Clinical and radiologic explorations suggested nephroblastoma. The diagnosis of rhabdoid tumor was made post operatively based on anatomopathological findings.


Author(s):  
Graciela Argote-Romero

Wilms tumor, known as well as nephroblastoma, is the most common primary malignant renal tumor in children. Over 95% of all renal tumors in patients under the age of 15 are Wilms tumors. The mean age at the time of diagnosis is 3.5 years. Wilms tumors are usually an incidental finding, a large abdominal mass discovered by a family member or pediatrician. Hematuria and hypertension can be present at the time of initial diagnosis. Up to 8% of the patients will have von Willebrand disease; therefore, all patients should have baseline coagulation studies. All patients should have either computed tomography of the abdomen and pelvis with oral and intravenous contrast or magnetic resonance imaging of the abdomen and pelvis with gadolinium. Treatment includes radical nephrectomy, chemotherapy, and, in some cases, radiotherapy. Emergency surgery is rarely. The disease-free survival rate is 86% for favorable-histology tumors and 64% for anaplastic tumors.


2017 ◽  
Vol 2017 ◽  
pp. 1-3 ◽  
Author(s):  
Ali Ridha ◽  
Njideka Oguejiofor ◽  
Sarah Al-Abayechi ◽  
Emmanuel Njoku

Abdominal actinomycosis is a rare infectious disease, caused by gram positive anaerobic bacteria, that may appear as an abdominal mass and/or abscess (Wagenlehner et al. 2003). This paper presents an unusual case of a hemodynamically stable 80-year-old man who presented to the emergency department with 4 weeks of worsening abdominal pain and swelling. He also complains of a 20-bound weight loss in 2 months. A large tender palpable mass in the right upper quadrant was noted on physical exam. Laboratory studies showed a normal white blood cell count, slightly decreased hemoglobin and hematocrit, and mildly elevated total bilirubin and alkaline phosphatase. A CT with contrast was done and showed a liver mass. Radiology and general surgery suspected malignancy and recommended CT guided biopsy. The sample revealed abundant neutrophils and gram positive rods. Cytology was negative for malignancy and cultures eventually grew actinomyces. High dose IV penicillin therapy was given for 4 weeks and with appropriate response transitioned to oral antibiotic for 9 months with complete resolution of symptoms.


Open Medicine ◽  
2010 ◽  
Vol 5 (1) ◽  
pp. 136-139 ◽  
Author(s):  
Savas Yakan ◽  
Safak Oztürk ◽  
Mustafa Harman ◽  
Oktay Tekesin ◽  
Ahmet Coker

AbstractGossypiboma (retained surgical sponge) is a pseudotumor within the body that is composed of non-absorbable surgical material with a cotton matrix. Because the symptoms of gossypiboma usually are nonspecific and may appear years after surgery, the diagnosis of gossypiboma may be difficult because the condition may mimic a benign or malignant soft-tissue tumour in the abdomen and pelvis. A 61-year-old woman with a one-year history of left upper-quadrant pain and weight loss was referred to our center. She had undergone peptic ulcer perforation 23 year ago. Physical examination revealed dullness and palpable mass in the left upper abdomen. On examination by computed tomography (CT), a hypodense mass of 12 cm in diameter between the greater curvature of the stomach, pancreas, and splenic hilus was detected. Upon exploration, a mass lesion of 10 cm in diameter was detected between the greater curvature of the stomach and splenic hilus, which caused dense adhesions not in communication with the pancreas. It was excised and a splenectomy was performed. After a macroscopic examination, the mass lesion was diagnosed as gossypiboma. Although ultrasonography (US), CT, angiography, and magnetic resonance imaging (MRI) may be used to diagnose gossypiboma, definitive diagnosis is possibile only upon surgery or histopathological examination. As a result, when an abdominal mass is observed, surgeons should carefully investigate the patient’s past surgical history while taking the possibility of gossypiboma into consideration.


2019 ◽  
Vol 65 (12) ◽  
pp. 1496-1501 ◽  
Author(s):  
Bruna M de Sá Pereira ◽  
Rafaela Montalvão de Azevedo ◽  
Joaquim Caetano de Aguirre Neto ◽  
Clarice Franco Menezes ◽  
Karla Emília Rodrigues ◽  
...  

SUMMARY Childhood renal tumors account for ~7% of all childhood cancers, and most cases are embryonic Wilms’ tumors (WT). Children with WT are usually treated by either COG or SIOP. The later treats the children using preoperative chemotherapy, but both have around 90% of overall survival in five years. WT is a genetically heterogeneous group with a low prevalence of known somatic alterations. Only around 30% of the cases present mutation in known genes, and there is a relatively high degree of intra-tumor genetic heterogeneity (ITGH). Besides potentially having an impact on the clinical outcome of patients, ITGH may interfere with the search for molecular markers that are prospectively being tested by COG and SIOP. In this review, we present the proposal of the current UMBRELLA SIOP Study 2017/Brazilian Renal Tumor Group that requires the multi-sampling collection of each tumor to better evaluate possible molecular markers, as well as to understand WT biology


Author(s):  
Aulia Rahmani ◽  
Nur Melani Sari ◽  
Vita Indriasari

Background: Overall five-year survival rate of Wilm’s Tumor (WT) in developing countries is still poor. Delayed diagnosis is one of the contributing factors, whereas early diagnosis is an important thing for the outcome. It is caused by the WT burden in developing countries that was not comparable with the number of facilities for diagnosis and treatment. Ultrasonography (USG) is the mandatory first-line imaging modality in children with a suspected abdominal mass and an overall sensitivity of 76%. Additionally, it can be found in many health facilities at a lower cost, quick, non-invasive, and carries no risk of radiation. Therefore, the relationship between USG and histopathology should be measured. Materials and Methods: A cross-sectional study with an analytical approach was performed in pediatric (0 untill 18 year of age) renal malignancy and neuroblastoma that admitted to Dr. Hasan Sadikin Hospital, Bandung between 2015-2018. Data were collected from medical records. Statistical analyses using Fisher exact test were done to determine the significance of the relationship between USG and histopathology. Results: Forty-three samples were obtained based on inclusion criteria, such as WT (n=33), neuroblastoma (n=6), renal clear cell carcinoma (n=2) and no specific type of renal malignancy (n=2). Fisher exact test revealed no-significant relationship between USG and histopathology with p-value > 0.05 Conclusion: There is no significant relationship between USG and histopathology. Therefore, centralized unity for USG interpretation is recommended.


1989 ◽  
Vol 11 (6) ◽  
pp. 172-179
Author(s):  
Marshall Z. Schwartz ◽  
Donald B. Shaul

The presence of an abdominal mass in the neonatal period is common, occurring in approximately 1 infant in 1000 live births. Despite this relatively high incidence, the finding of an abdominal mass in a neonate can be alarming for both parents and physicians. Until recently, the identification of an abdominal mass was made by physical signs (ie, abdominal distention, palpable mass). However, in the past decade, fetal ultrasound has become technically refined and is more widely practiced. As a result, the presence of an abdominal mass in the fetus may be known long before birth, allowing for the formation of a specific diagnosis and treatment plan. In addition to fetal ultrasonography, a wide array of sophisticated imaging techniques have become available to aid in the diagnosis of an abdominal mass. However, in the cost-conscious environment in which health care must be provided, it is the physician's responsibility to evaluate an abdominal mass as cost effectively as possible. Early consultation among the pediatrician, pediatric radiologist, pediatric surgeon, and, in the case of prenatal diagnosis, the obstetrician can expedite this process. Many abdominal masses are of the nonsurgical variety (ie, organomegaly or bladder distention). Most masses requiring surgical intervention are benign (87%), and the prognosis for neonates with an abdominal mass is good.


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