Abdominal Masses in the Newborn

1989 ◽  
Vol 11 (6) ◽  
pp. 172-179
Author(s):  
Marshall Z. Schwartz ◽  
Donald B. Shaul

The presence of an abdominal mass in the neonatal period is common, occurring in approximately 1 infant in 1000 live births. Despite this relatively high incidence, the finding of an abdominal mass in a neonate can be alarming for both parents and physicians. Until recently, the identification of an abdominal mass was made by physical signs (ie, abdominal distention, palpable mass). However, in the past decade, fetal ultrasound has become technically refined and is more widely practiced. As a result, the presence of an abdominal mass in the fetus may be known long before birth, allowing for the formation of a specific diagnosis and treatment plan. In addition to fetal ultrasonography, a wide array of sophisticated imaging techniques have become available to aid in the diagnosis of an abdominal mass. However, in the cost-conscious environment in which health care must be provided, it is the physician's responsibility to evaluate an abdominal mass as cost effectively as possible. Early consultation among the pediatrician, pediatric radiologist, pediatric surgeon, and, in the case of prenatal diagnosis, the obstetrician can expedite this process. Many abdominal masses are of the nonsurgical variety (ie, organomegaly or bladder distention). Most masses requiring surgical intervention are benign (87%), and the prognosis for neonates with an abdominal mass is good.

2017 ◽  
Vol 2 (1) ◽  

Introduction: Abdominal masses in the neonatal period often present a diagnostic challenge. The aim of this study was to evaluate which urological pathologies cause the formation of a neonatal mass, the diagnostic pathway and surgical outcome. Patients and methods: The medical and radiological records of 30 neonates who were admitted to the Neonatal Surgical Unit of Yorkhill Sick Children Hospital, Glasgow with an abdominal mass over a five-year period (2008-2013) were reviewed. Data collected included demographics, gestational age, radiological investigations, operative findings and complications. Result: Seventeen neonates (9 males, 8 females) were identified with an abdominal mass arising from the urological tract. Four boys were found to have posterior urethral valves while in 4 girls a duplex kidney with a ureterocele was identified. In the remaining 9 patients the palpable mass was caused by: vesicoureteric reflux (n=2), multicystic dysplastic kidney (n=2), polycistic kidney disease (n=1), ectopic kidney (n=1), pelvi-ureteric junction obstruction (PUJO) (n=1), unilocular renal cyst (n=1), PUJO and vesicoureteric junction obstruction (n=1). Nine patients required a form of urinary diversion and in two of these patients a nephrostomy was followed by a pyeloplasty, 2 required incision of ureteroceles, 1 nephrectomy, 1 partial nephrectomy, 1 STING and 1 primary valve ablation. Conclusion: Only 70% of newborns with abdominal masses were diagnosed antenatally, while 30% were detected postnatally. Posterior urethral valves remain the most common cause of a neonatal mass in a male, while duplex kidneys with ureterocele were seen in girls. Half of the patients will require a form of urinary diversion in the neonatal period. The large majority (88%) of abdominal masses of urological origin required surgical intervention.


2020 ◽  
Vol 8 (2) ◽  
pp. 41-49
Author(s):  
G. Mahender Reddy ◽  
M. L. Ravindernath ◽  
S.Snehaja Reddy

Background: In order to conduct appropriate surgical treatments, the characterization of ovarian lesions is of considerable significance and can affect patient care. A multidisciplinary approach based on physical assessment, laboratory tests and imaging techniques includes adequate measurement of the adnexal masses. The aim is to assess the role of Sonography and MR in diagnosing ovarian masses, to study imaging characteristics of ovarian masses on USG and Doppler in correlating these findings with MR features. Subjects and Methods: The present study was carried out in the department of radiodiagnosis to determine the efficacy of sonography and MRI in the diagnosis of ovarian masses. The study group comprised 50 patients with clinically suspected ovarian masses and imaging was carried out on all patients with ovarian masses and imaging was carried out on all patients with ovarian masses. All the masses were evaluated on sonography based on the Sassone scoring system. Morphological analysis was performed for each mass based on wall thickness, inner wall structure, septal structure and echogenicity of mass. The color flow was carried out, subsequently; MRI was carried out for each patient. Radiological diagnosis was confirmed after surgery on histopathological examination. Results: The majority of the patients were in the age group of 31-40 years. The most common symptoms noted were pain in the abdomen. The most common clinical finding was a palpable mass. The application of Sassone sonomorphologic score >9 was identified in 8 masses, out of which 7 were malignant and 1 was a benign lesion. The colour flow was detected in 38 out of 50 masses. The presence of flow, type of flow, vessel arrangement, morphology and location were noted and on pulsed Doppler the RI and PI values were calculated. Out of 8 malignant cases, 5 were diagnosed as malignant according to the Caruso score. The overall sensitivity 100 %, specificity is 97.6% and diagnostic accuracy is 98% of MRI which is higher than that of ultrasound and CDS. Conclusion: We conclude that MRI is a superior diagnostic modality in establishing the diagnosis of ovarian masses.


2008 ◽  
Vol 126 (4) ◽  
pp. 229-231 ◽  
Author(s):  
Sergio Renato Pais Costa ◽  
Nivaldo Marques Cabral ◽  
Ademir Torres Abhrão ◽  
Ricardo Borges da Costa ◽  
Lilian Mary da Silva ◽  
...  

CONTEXT: Cystic pheochromocytomas are uncommon neuroendocrine tumors that originate from the adrenal medulla. Differing from the more frequent solid pheochromocytomas, which produce catecholamines and present adrenergic syndrome, cystic pheochromocytomas may not produce these. Their symptoms are generally associated with an abdominal mass or even pain, particularly if the mass attains large dimensions. Similarly, radiological diagnosis may also be difficult. Right-side lesions may be confounded with cystic hepatic tumors or even retroperitoneal sarcomas with cystic areas, using radiological methods. Sometimes, there may be a preoperative diagnosis of malignancy. Invasion of organs in this region (i.e. liver or kidney), or even the presence of a large retroperitoneal mass (of uncertain origin) with which multiple organs are involved, may be indicative of malignant origin. CASE REPORT: Two cases of giant cystic pheochromocytoma that invaded the right hepatic lobe are described. These presented as abdominal masses. Both cases were malignant. They were treated by radical right nephrectomy plus right hepatectomy.


Author(s):  
David A. Mitchell ◽  
Laura Mitchell ◽  
Lorna McCaul

Contents. Relevant pages in other chapters. Principal sources. Listen, look, and learn. Presenting complaint. The dental history. The medical history. Medical examinatio. Examination of the head and neck. Examination of the mouth. Investigations—general. Investigations—specific. Radiology and radiography. Advanced imaging techniques. Differential diagnosis and treatment plan.


2020 ◽  
Vol 13 (12) ◽  
pp. e236858
Author(s):  
Rahul Kumar ◽  
Tripti Prajapati ◽  
Rahul Verma ◽  
Pankaj Kumar Garg

Gastric teratoma is a rare entity beyond infancy and usually presents as a slow-growing asymptomatic abdominal mass. There are a few published reports of these tumours seen in patients beyond the age of 1 year. In resource-constrained population, these masses are usually neglected because of minimal symptoms associated with these tumours. We report a case of a 14-year-old adolescent who was diagnosed to have a large primary gastric teratoma and underwent en bloc excision with wedge resection of the stomach. A systematic review to identify the previously reported cases of primary gastric teratoma in patients of over the age of 1 year in last 50 years yielded only five articles. A high index of suspicion for primary gastric teratomas in young children and adolescents presenting with asymptomatic large abdominal masses would help treat these patients with a curative intent and excellent treatment outcomes.


2020 ◽  
Vol 16 (1) ◽  
Author(s):  
Johnathan Zeng ◽  
Matthew F. Starost ◽  
Michal Mauda-Havakuk ◽  
Andrew S. Mikhail ◽  
Ari Partanen ◽  
...  

Abstract Background Teratomas are germ cell neoplasms composed of a wide variety of tissues. In the woodchuck, only one testicular teratoma has been described in the literature. The objective of this report was to describe the radiologic and pathologic findings in a female woodchuck (Marmota monax) with an ovarian teratoma consisting of mature tissues originating from all three germ layers. Case presentation A 2-year-old female woodchuck that had been infected at birth with woodchuck hepatitis virus and subsequently developed hepatocellular carcinoma was incidentally discovered to have a mobile 6.6 × 4.8 × 4.7 cm abdominal mass on computed tomography (CT) imaging. The tumor was predominantly solid and heterogenous on CT with soft tissue, fat, and areas of dense calcification. The teratoma did not enhance with intravenous contrast administration. On ultrasound, the tumor was solid with heterogeneous echogenicity, reflecting the fat content and areas of calcification. Sonolucent areas were present that may have represented cysts. There was heterogeneously increased signal on T1-weighted magnetic resonance imaging (MRI) and heterogeneous hyperintensity in T2-weighted imaging. Fat was evident within the tumor. At necropsy, the tumor was attached to the distal end of the right uterine horn. Histopathology showed mature tissue types representing all three germ layers. Conclusions Ovarian teratoma should be considered in the differential diagnosis of ovarian or abdominal masses in woodchucks. The tumor displayed mature tissue derived from all three germ layers. CT, ultrasound, and MRI findings were presented in detail and matched the typical imaging appearance of teratomas.


1988 ◽  
Vol 74 (3) ◽  
pp. 365-367
Author(s):  
Alessandro Zerbi ◽  
Marco Braga ◽  
Alessandro Sironi ◽  
Agostino Faravelli ◽  
Valerio Di Carlo

A large exogastric leiomyoblastoma in a 48-year-old male revealed by asymptomatic upper abdominal mass is reported. Abdominal ultrasound, computerized tomography scan and magnetic resonance showed a 20 cm cystic lesion apart from liver and pancreas of undetermined origin. During hospitalization, massive intraperitoneal bleeding due to rupture of the mass was observed. An emergency laparotomy was carried out, and excision of a large, ruptured, cystic mass involving the greater gastric curvature was performed. Microscopy revealed a gastric leiomyoblastoma. Even if infrequent, massive intraperitoneal bleeding is a very serious complication of gastric leiomyoblastoma. Considering the difficulty of an accurate preoperative diagnosis and the risk of intraperitoneal rupture, the authors suggest that similar abdominal masses should be managed by quick diagnostic investigations and early surgical procedures.


2017 ◽  
Vol 9 (3) ◽  
Author(s):  
Luisa Ferrero ◽  
Riccardo Guanà ◽  
Giulia Carbonaro ◽  
Maria Grazia Cortese ◽  
Luca Lonati ◽  
...  

Benign intra-abdominal cystic masses in infancy are fairly uncommon and their etiopathogenesis, histology and clinical presentation differ significantly. Our aim is to report our experience in their treatment in order to discuss the best diagnostic and treatment modality. The medical records of 5 children (2M, 3F) with cystic intraabdominal masses referred to our hospital between November 2012 and September 2016, were retrospectively reviewed. All patients underwent open surgery and subsequent histopathologic analysis. Different clinical presentations, localizations of the masses, diagnostic tools, surgical approaches, histological examinations and outcomes were reviewed. Patients mean age was 5.4 years (range: 8 months-9 years). Two patients presented recurrent abdominal pain and abdominal distension; 1 patient had a palpable mass discovered incidentally and 2 complained acute abdominal pain. Routine laboratory tests, tumor markers and abdominal ultrasound were immediately done in all patients. Three patients underwent MRI and 1 abdominal CT. At laparotomy 2 hepatic cysts, 2 mesenteric cyst and 1 retroperitoneal cyst were discovered. Histology reports described: 1 hepatobiliary cystadenoma, 1 benign hepatic hamartoma and 3 cystic lymphangiomas (1 retroperitoneal and 2 mesenteric). There were no major postoperative complications, deaths, or recurrences in our series (follow-up 3-24 months). Despite the rarity of these lesions, benign cystic abdominal masses in children are not so uncommon and should be considered as causes of acute abdominal pain. The differential diagnosis is not always possible preoperatively. In our series, radical excision of the lesions was possible in all cases, allowing reliable histological results and avoiding recurrences.


2009 ◽  
Vol 27 (15_suppl) ◽  
pp. e15030-e15030
Author(s):  
A. F. Sobrero ◽  
E. Bennicelli ◽  
A. Pessino ◽  
A. Guglielmi ◽  
S. Mammoliti ◽  
...  

e15030 Background: Imatinib inhibits PDGFR interfering with pericytes, the structural support to newly formed tumor blood vessels. It may thus synergize with bevacizumab. Microenvironment and tumor targeted agents along with chemotherapy could be a promising add-on approach. Methods: cetuximab 500 mg/m2, bevacizumab 5 mg/kg and modified FOLFOX-6 were given i.v. on day 1 and repeated every 2 weeks. Imatinib 400 mg/day per os was given continuously. Due to the cost and potential toxicity of the combination, the endpoint for this phase II study was very ambitious: at least 25% of complete response (medically or surgically achieved), lasting a minimum of 12 months in advanced untreated colorectal cancer patients with clearly unresectable disease. Results: Of 26 patients (16 with 1 site of disease), 17 completed the first 4 months of treatment according to the protocol, while 9 had to discontinue one biologic drug due to side effects (5 cetuximab, 3 imatinib and 1 bevacizumab). Grade 3–4 toxicity: diarrhea 12%, neutropenia 24%, skin rash 24%, hypersensitivity reactions 16%, asthenia 8%, neuro 8%. All patients were evaluable for response. Eleven responses ( 1 CR and 10 PR), 13 SD and 2 PD were observed, corresponding to 42% RR ( 95% CI = 23–61). The minimum follow up is 12 months; median PFS is 10 months. One patient among responders underwent radiofrequency ablation and 17 patients underwent surgery: 8 R-0, 3 R-1, 5 R-2 and one exploratory laparotomy. Major post surgical complications occurred in 5/17 patients. No evidence of macroscopic disease after the entire treatment plan was obtained in 13/26 patients: 12 surgical and 1 medical CR. Seven/13 were disease free at 6 months, but only 3 were still disease free at 12 months. ERCC1, ERCC2/XDP, GSTP1,TS,EGF, COX2, CYCLIN D, FCgR polymorphisms and K-RAS mutations were evaluated on all 26 patients, but no correlations were found with clinical outcome. Conclusions: The triple combination of biologics with modified FOLFOX-6 is feasible and tolerable as initial aggressive treatment. The primary endpoint of the study was not met . In fact the activity, 42% RR, was not outstanding and the high resectability rate, 69%, is misleading in the light of the short duration of the surgically induced CR. [Table: see text]


2011 ◽  
Vol 26 (S2) ◽  
pp. 1717-1717 ◽  
Author(s):  
C. Forchuk ◽  
R. Vann ◽  
E. Wilura ◽  
J. Hoch ◽  
M. Jeng ◽  
...  

In London, Ontario, discharges from psychiatric wards to shelters or NFA occurred 194 times per year. This discovery led to the creation of a pilot project that provided immediate access to a housing advocate and changed normal policies related to housing and start-up fees for a select group of income support recipients. The intervention was successful; seven participants who received this additional assistance were still housed six months later, whereas 6 of 7 who received usual care were still homeless. The goal of the current study was to determine the strengths and areas for improvement of a method to prevent discharge from hospital to NFA and suggest improvements in preparation for wider implementation.Phase 2: intervention to all acute psychiatric patients within a general hospital.Phase 3: intervention to all patients within a specialized tertiary care psychiatric hospital. Intervention included on-ward access to a housing advocate and income support staff which was facilitated through computer linkages to housing and income databases.Findings revealed the success of the intervention across both acute and tertiary sites. All hypotheses were supported: the rate of discharge to homelessness decreased; those accessing the service were poor; and the cost savings from the program exceeded the cost of implementation. Advantages of the approach included: accessibility and convenience of services on site, positive influence on overall treatment plan and feelings of independence and support. Results reveal the positive influence a cross-sectoral approach has on preventing discharge from psychiatric wards to the streets and shelters.


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