scholarly journals Synovial sarcoma of the spine: A case report and review of the literature

2020 ◽  
Vol 11 ◽  
pp. 257
Author(s):  
Fayez Dhafer Alshehri ◽  
Salem Khaled Baeshen ◽  
Alaa Mohammed Noor Samkari ◽  
Abeer Salim Almehdar ◽  
Ahmed Ibrahim Lary
Keyword(s):  
Synovial Sarcoma ◽  
Rare Case ◽  
Treatment Strategies ◽  
Surgical Excision ◽  
Treatment Modalities ◽  
Adjuvant Radiation ◽  
Paraspinal Muscles ◽  
Malignant Soft Tissue Tumor ◽  
Poor Outcomes

Background: Synovial sarcoma (SS) of the spine is a rare malignant soft-tissue tumor, and there are few reported cases. The aim of this paper is to report a rare case of spinal SS involving the paraspinal muscles, and to review all such cases reported in the literature. Case Description: In this paper, we report a rare case of spinal SS involving the paraspinal muscles in a 12-year-old girl. The patient underwent surgical excision of the mass with adjuvant radiation and chemotherapy. At the 1-year follow-up, there was no evidence of local tumor recurrence, and the patient’s symptoms had improved. In addition, we identified and reviewed 33 reported cases of SS involving the spine. Conclusion: Due to the limited number of reported cases in the literature, it is difficult to predict the outcomes of spinal SS. Further, different treatment modalities have been used to treat spinal SS. However, most of the reported cases had poor outcomes. Therefore, prospective multi-center studies are needed to further investigate the treatment strategies and outcomes for patients with spinal SS.

scholarly journals Intraarticular Synovial Sarcoma Causing Chronic Wrist Pain: A Rare Case Report

2020 ◽  
Vol 7 (3) ◽  
pp. 141-146
Author(s):  
Farid Najdmazhar ◽  
◽  
Tina Shooshtarizadeh ◽  
Seyed Matin Sadat Kiaei ◽  
◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Synovial Sarcoma ◽  
Rare Case ◽  
Surgical Excision ◽  
Wrist Pain ◽  
Joint Involvement ◽  
Rare Case Report ◽  
Chronic Wrist Pain

Synovial Sarcoma (SS) is a rare and aggressive sarcoma that usually occurs around the knee joint; it rarely involves the hand. Joint involvement by SS is extremely rare. We report a case of wrist intraarticular SS presenting with chronic wrist pain. The patient underwent surgical excision alongside with local radiotherapy and chemotherapy. After 24 months of follow up, there was no recurrence or metastasis. Intraarticular SS should be in a differential diagnosis list of chronic wrist pain even though it is extremely rare.

Systematic literature review of clinical outcomes in adults with metastatic or advanced synovial sarcoma

2020 ◽  
Vol 16 (35) ◽  
pp. 2997-3013
Author(s):  
Kentaro Kogushi ◽  
Michael LoPresti ◽  
Shunya Ikeda
Keyword(s):  
Synovial Sarcoma ◽  
High Frequency ◽  
Clinical Evidence ◽  
Systemic Treatment ◽  
Progression Free Survival ◽  
Treatment Modalities ◽  
Free Survival ◽  
New Treatment ◽  
Poor Outcomes

Background: Synovial sarcoma (SS) is a rare, aggressive soft tissue sarcoma with a poor prognosis after metastasis. The objective of this study was to conduct a systematic review of the clinical evidence for therapeutic options for adults with metastatic or advanced SS. Materials & methods: Relevant databases were searched with predefined keywords. Results: Thirty-nine publications reported clinical data for systemic treatment and other interventions. Data on survival outcomes varied but were generally poor (progression-free survival: 1.0–7.7 months; overall survival: 6.7–29.2 months) for adults with metastatic and advanced SS. A high frequency of neutropenia with systemic treatment and low quality of life post-progression were reported. Conclusion: Reported evidence suggests poor outcomes in adults with metastatic and advanced SS and the need for the development of new treatment modalities.

scholarly journals Primary maxillofacial chordoma: a rare case report and literature review

2019 ◽  
Vol 47 (9) ◽  
pp. 4575-4579
Author(s):  
Yu Cui ◽  
Xiang-yan Cui ◽  
Tingting Yu ◽  
Zhan-peng Zhu ◽  
Xin Wang
Keyword(s):  
Adjuvant Radiotherapy ◽  
Rare Case ◽  
Postoperative Radiotherapy ◽  
Eastern Cooperative Oncology Group ◽  
Treatment Strategies ◽  
Comprehensive Treatment ◽  
Neck Lymph Node ◽  
Group Score ◽  
Rare Case Report

Primary maxillofacial chordoma is extremely rare. We herein report a very rare case of a recurrent maxillofacial chordate tumor that was diagnosed in a 56-year-old woman who underwent three tumor resections. After surgical treatment, the patient healed well with an Eastern Cooperative Oncology Group score of 1. She was discharged to a local hospital for adjuvant radiotherapy. Close follow-up was ongoing at the time of this writing. Radical surgery and adjuvant radiotherapy remain the main treatment strategies for chordoma. Postoperative radiotherapy is particularly important. Our experience is to administer a total dose of 50 Gy to a clearly delineated target. If appropriate comprehensive treatment is available, distant metastasis of primary chordoma is rare, and neck dissection is therefore not generally recommended. Neck lymph node dissection is generally not recommended.

scholarly journals Gingival Lipoma: A Rare Case Report

2017 ◽  
Vol 1 (1) ◽  
pp. 37-39
Author(s):  
Sweta Shrestha ◽  
Shaili Pradhan ◽  
Ranjita Shrestha Gorkhali
Keyword(s):  
Rare Case ◽  
Surgical Excision ◽  
Soft Tissue Tumors ◽  
Rare Case Report ◽  
Postsurgical Complication ◽  
Benign Tumours ◽  
One Year ◽  
Slow Growing ◽  
Oral Soft Tissue

Lipomas are benign tumours of mesenchymal origin (mature adipocytes) that are comparatively uncommon in the oral cavity corresponding to less than 4.4% of all benign oral soft tissue tumors. Clinically, they present as slow growing, soft, asymptomatic masses. Histopathologically, they appear as thinly encapsulated lesion composed of mature adipocytes with inconspicuous vascularity. The pathogenetic mechanisms of oral lipomas are still unclear. They are usually treated by surgical excision and bear excellent prognosis. Here we report a case of intraoral lipoma in 54 year old male patient in the left lower lingual alveolar mucosal region that was treated by surgical excision using electrocautery without any postsurgical complication. One-year follow-up showed no evidence of recurrence.

A Rare Case of Nasopharyngeal Glial Heterotopia in a Neonate

2021 ◽  
pp. 097321792110425
Author(s):  
Viveka Singh ◽  
Neha Nabar ◽  
Sanjiv Badhwar ◽  
Preetha Joshi
Keyword(s):  
Gold Standard ◽  
Rare Case ◽  
Neural Tissue ◽  
Surgical Excision ◽  
Intracranial Extension ◽  
Resonance Imaging ◽  
Radiological Studies ◽  
Rule Out ◽  
Glial Heterotopia

Nasopharyngeal glial heterotopias is an extremely rare, nonhereditary, developmental malformation manifesting as a mass composed of mature neural tissue with no intracranial continuity. Glial heterotopia is a rare, non-neoplastic, extracranial midline malformation. Nasal glioma is the most frequently encountered entity among congenital nasal masses. Cases which are associated with intracranial extension are termed as encephalocele. It must be considered in the differential diagnosis of airway obstruction in neonates. Magnetic resonance imaging is mandatory to rule out intracranial extension. We report a rare case of heterotopic brain tissue in nasopharynx with no intracranial extension to attract attention to the diagnostic workup of nasopharyngeal obstruction in a neonate with respiratory distress. Clinical examination and radiological studies are diagnostic while early surgical excision and histopathological confirmation is the gold standard. This baby underwent complete intranasal endoscopic excision of mass on day 20 of life. The postoperative course was uneventful and the baby is growing well on follow-up. This case would be one of the few cases reported from India.

scholarly journals PEComa of soft tissues can mimick lymph node relapse in patients with history of testicular seminoma

2013 ◽  
Vol 7 (9-10) ◽  
pp. 651 ◽  
Author(s):  
Gabriele Guglielmetti ◽  
Paolo De Angelis ◽  
Paolo Mondino ◽  
Carlo Terrone ◽  
Alessandro Volpe
Keyword(s):  
Lymph Node ◽  
Soft Tissue ◽  
Soft Tissues ◽  
Percutaneous Biopsy ◽  
Surgical Excision ◽  
Pelvic Lymphadenectomy ◽  
Adjuvant Radiation ◽  
Soft Tissue Neoplasm ◽  
Testicular Seminoma

Perivascular Epithelioid Cell tumour (PEComa) is rare. We describe a 39-year-old man who underwent a left radical orchidectomy and adjuvant radiation therapy for a stage IA classical testicular seminoma. He was diagnosed with a mass lateral to the right common iliac artery that was considered suspicious for late lymph node relapse after 3 years of follow-up. Due to the unusual location of the mass and the equivocal findings of percutaneous biopsy, a laparoscopic pelvic lymphadenectomy was performed. Final pathology revealed PEComa of soft tissue. The patient is disease free after 38 months of follow-up without adjuvant treatment. The presence of rare soft-tissue neoplasm should be considered in differential diagnosis of retroperitoneal masses during follow-up of germ cell tumours. Suspicious isolated recurrences of these neoplasms in unusual locations can require surgical excision to confirm diagnosis and avoid inappropriate treatment.

scholarly journals Congenital Arteriovenous Malformations: A Follow-Up of Treatment

2005 ◽  
Vol 13 (1) ◽  
pp. 23-26 ◽  
Author(s):  
Jh Phillips ◽  
Cl Tang ◽  
D Armstrong ◽  
T De Chalain ◽  
R Zuker
Keyword(s):  
Patient Outcomes ◽  
Arteriovenous Malformations ◽  
Vascular Malformations ◽  
Treatment Strategies ◽  
Parent Satisfaction ◽  
Surgical Excision ◽  
Complete Excision ◽  
Satisfaction With Treatment ◽  
Sick Children

Due to the rarity of arteriovenous malformations (AVMs), there is a paucity of information on the outcomes of various treatments. Presently, the mainstays of treatment of an AVM are embolization, surgical excision or a combination of both. A retrospective study of 26 patients with AVMs treated at the Hospital for Sick Children, Toronto, Ontario between 1985 and 1995 was performed. The treatment strategies and patient outcomes were compared in terms of efficacy, complications and the response of patients and their families to their overall treatment. The overall findings showed that embolization alone was effective in controlling symptoms, but may be associated with an increased AVM size. A partial excision of an AVM does not appear to exacerbate recurrence, as has been previously reported. In fact, even after what appears to be a complete excision of the AVM, recurrence may still occur. Complications from a surgical excision of the AVM are more frequent but less devastating than complications from embolization of the lesion. The overall patient or parent satisfaction with treatment was high with respect to improvement in outcome. It is expected that with an increasing understanding of vascular malformations, and the evolution of interventional radiological techniques, complications will decrease and results as a whole will improve.

Healthcare (HC) utilization and costs in patients (pts) with newly diagnosed metastatic thyroid cancer (mTC)

2007 ◽  
Vol 25 (18_suppl) ◽  
pp. 17082-17082 ◽  
Author(s):  
A. Berger ◽  
J. Edelsberg ◽  
K. Chung ◽  
A. Ngyuyen ◽  
D. Stepan ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Metastatic Disease ◽  
Index Date ◽  
Average Length ◽  
Treatment Strategies ◽  
Treatment Modalities ◽  
Newly Diagnosed ◽  
Office Visits ◽  
Antibody Testing

17082 Background: mTC is relatively rare and little is known about treatment patterns or HC costs in patients with newly diagnosed disease. Methods: Retrospective longitudinal cohort study. Using a large (∼14 million covered lives) US health-insurance claims database, we identified a cohort of pts with diagnoses of thyroid cancer (ICD-9-CM diagnosis codes 193.XX) and distant metastatic disease (197.XX-198.XX) between 1/1/2003 and 12/31/2005 (“study period”); the date of first mention of metastatic disease was designated the “index date”. All pts were required to be =18 years of age as of their index date and to have been continuously enrolled in the database for =6 months prior to this date. Pts were followed from their index date until health plan disenrollment (for any reason) or end of the study period, whichever occurred first. Utilization of HC services and costs (total reimbursed amount including pt liability) were then examined during each quarter of follow-up (eg, first 3 months of follow-up=Q1). Results: 183 pts met all study entry criteria. Mean (±SD) age was 51.5 (11.8) years; mean duration of follow-up was 344 days (median=275 days). Most common management/treatment strategies during Q1 included: imaging [eg, US/CT of the neck (49.7%)], thyroglobulin/thyroglobulin antibody testing (25.7%); radiation therapy (23.0%); I131 therapy (19.1%); thyroid surgery (12.6%); chemotherapy (10.9%); lymphadenectomy (8.7%); and bisphosphonate therapy (3.8%). In addition, during Q1, pts averaged 9.5 office visits (95% CI, 8.2, 10.9) and 0.6 hospitalizations (95% CI, 0.5, 0.7); for pts hospitalized during Q1, average length of stay was 6.6 (95% CI, 4.9, 8.4). Costs during the first 2 years of follow-up are presented in the table ; inpt care represented 43% of total HC costs. Conclusions: Many different treatment modalities are used in pts with newly diagnosed mTC; the cost of such care is substantial. [Table: see text] [Table: see text]

Synovial Sarcoma of the Brachial Plexus

Neurosurgery ◽  
2011 ◽  
Vol 70 (5) ◽  
pp. 1329-1333 ◽  
Author(s):  
Farhad Pirouzmand ◽  
Kavya Kommaraju ◽  
Kenneth J. Craddock ◽  
David Howarth
Keyword(s):  
Brachial Plexus ◽  
Synovial Sarcoma ◽  
Soft Tissue Tumor ◽  
Clinical Presentation ◽  
Clinical Course ◽  
Relevant Literature ◽  
Adjuvant Radiation ◽  
Malignant Soft Tissue Tumor ◽  
Malignant Soft Tissue ◽  
Firm Mass

Abstract BACKGROUND AND IMPORTANCE: Synovial sarcoma (SS) is a malignant soft-tissue tumor that rarely involves brachial plexus. The authors report a case of brachial plexus SS and review the relevant literature. CLINICAL PRESENTATION: A 53-year-old woman presented with gradually enlarging right subclavicular mass over 5 years associated with sharp aching pain radiating down toward the radial 3 fingers. On examination, she had a corresponding firm mass in the supraclavicular region with a positive Tinel sign. There was no objective neurological deficit. She underwent partial excision of this mass without any further adjuvant radiation or chemotherapy. Pathology was consistent with SS. CONCLUSION: Lack of any recurrence in this case 6 years after incomplete excision with no adjuvant therapy suggests slow clinical course in some of these sarcomas.

scholarly journals Scar endometriosis-rare and painful entity: a case report

2021 ◽  
Vol 10 (5) ◽  
pp. 2104
Author(s):  
Anita Yadav ◽  
Jyoti Baghel ◽  
Rajneesh Rawat ◽  
Avinash Prakash
Keyword(s):  
Rare Case ◽  
Rectus Sheath ◽  
Surgical Excision ◽  
Tertiary Level ◽  
Rare Entity ◽  
Pelvic Endometriosis ◽  
Rare Type ◽  
Detailed History ◽  
Scar Endometriosis

Scar endometriosis is a rare type of extra-pelvic endometriosis that develops following obstetrical and gynecological surgeries. It is a rare entity, though probably on the rise, due to the increase in caesarean sections performed worldwide. This manuscript reports a rare case of scar endometriosis involving rectus sheath following repeat caesarean section and was managed at a tertiary level centre. The patient required surgical excision of the lesion and was kept on regular follow-up following surgery. The physiopathology of scar endometriosis is complex; its symptomatology is rich and diverse but detailed history, thorough clinical examination along with imaging and histopathological evaluation is usually efficient in diagnosing the condition.

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