The comparative analysis of MRI data in the early period after lumbar microdiscectomies with epidural injection of polyacrylamide hydrogel

Objective: To perform a comparative analysis of MRI data obtained in the early postoperative period after repeated lumbar microdiscectomies in patients with and without epidural injection of “Nubiplant” polyacrylamide hydrogel (HG). Material and methods: The MRI data of the lumbar spine in the early postoperative period after repeated removal of herniated disc (on the 3-15th day) in 84 (100%) patients were analyzed: 30 (35,7%) patients were injected intraoperatively epidurally with “Nubiplant” HG to prevent epidural fibrosis (main group (MG) and in 54 (64,3%) patients the HG was not injected (control group (CG). Results: Comparative analysis of MRI data on the 3-15th day after surgery showed that the frequency of epidural edema and hemorrhage signs within the postoperative area in the MG was significantly lower as compared to the CG (p = 0,0444 and p = 0,0288 respectively). To assess the accuracy of the epidural administration of an artificial biopolymer Nubiplant during lumbar microdiscectomy, in the early postoperative period the following MRI criteria could be helpful: i) absence of the dural sac deformation and dislocations of the spinal root; ii) well-defined margin of the adjacent spinal root; iii) homogeneous MRI signals of the Nubiplant zone; iv) absence of Nubiplant areas outside the postoperative area; v) sufficient sectoral coverage of the adjacent root with epidurally administered Nubiplant (optimally >1800). Nubiplant” HG in the patients of the MG was evaluated, and MRI criteria for assessing the correctness of its introduction were proposed. Conclusions: In the early period after repeated lumbar microdiscectomies (on the 3-15th day), intraoperative epidural injection of “Nubiplant” HG was accompanied by a significant decrease of epidural edema and hemorrhage signs within the postoperative area. The proposed criteria of correctness of HG “Nubiplant” introduction allow unifying the approaches in radiological assessment of this patients.

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Changes in Indicators of Microcirculation in the Early Postoperative Period in the Treatment of Diaphyseal Fractures of the Shin Bones Using a Plate with Limited Contact

Acta biomedica scientifica ◽

10.29413/abs.2019-4.3.8 ◽

2019 ◽

Vol 4 (3) ◽

pp. 58-62

Author(s):

A. I. Plakhov ◽

L. I. Kolesnikova ◽

L. I. Korytov ◽

V. G. Vinogradov ◽

M. A. Darenskaya

Keyword(s):

Postoperative Period ◽

Lower Limb ◽

Blood Circulation ◽

Early Period ◽

Metal Plate ◽

Early Postoperative Period ◽

Control Group ◽

Doppler Flowmetry ◽

Results Of Treatment ◽

Diaphyseal Fractures

Background. Unsatisfactory results of treatment, such as delayed consolidation and non-fusion of fractures, the formation of false joints and limb bone defects, have no tendency to decrease. We can assume that one of the leading factors of complications in traumatology is a violation of microcirculation in the affected segment of the limb.Aims. To identify patterns of changes in the parameters of the microcirculatory bed of the damaged segment of the lower limb when fixing bone fragments with a plate with limited contact in the early period after surgery.Materials and methods. In 25 patients, we studied four parameters of microcirculation of the lower limb segment with application of laser Doppler flowmetry. The control group consisted of 25 healthy volunteers, comparable in age and sex with the study group.Results. We found that in the early postoperative period (from the first to the 10th day after the surgery) in patients with diaphyseal fractures of the tibia operated with metal plate with limited contact there was an increase in microcirculation by 75.69 %, an increase in the proportion of the nutritive component of microcirculation compared to the shunt fraction by 24.64 %, as well as an increase in more than one ratio of the amplitude of the heart and respiratory range. All of that indicates a local circulatory disorder in the nutritive arterial hyperemia. We note that the increase in the amplitude of the respiratory component by 17.22 % and the equality of the amplitude of the cardiac range compared with the control group indicate violations of local blood circulation by the type of venous stagnation.Conclusion. On the basis of the results obtained, we note that patients with diaphyseal fractures of the shin bones treated with metal osteosynthesis with a plate with limited contact in the early postoperative period develop a violation of local blood circulation in the stagnant-hyperemic type.

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Comparative analysis of the results of computerized phonoenterography in patients with acute destructive appendicitis before surgery and in the postoperative period

I P Pavlov Russian Medical Biological Herald ◽

10.23888/pavlovj20173469-475 ◽

2017 ◽

Vol 25 (3) ◽

pp. 469-475

Author(s):

K. V. Philippova ◽

O. V. Zaitsev

Keyword(s):

Abdominal Pain ◽

Comparative Analysis ◽

Acute Appendicitis ◽

Postoperative Period ◽

Spectral Power ◽

Abdominal Cavity ◽

Pain Syndrome ◽

Acoustic Signals ◽

Early Postoperative Period ◽

Control Group

Using the method of computerized phonoenterography we made an analysis of motor-evacuation function of the gastrointestinal tract in 35 patients with acute destructive appendicitis before surgery and in the postoperative period and in 30 patients without abdominal pain syndrome and concomitant pathology of the organs of the abdominal cavity. The obtained results of computerized phonoenterography different in the group of patients with acute appendicitis before appendectomy in comparison with group of patients without acute abdominal pathology (control group). For patients after appendectomy statistically significant differences with the control group in the vast majority of bands wasn’t obtained. Given the fact that the densities of the spectral power of acoustic signals of the abdominal cavity to assess the motor-evacuation function of the intestine in these groups of patients, we showed a reduction of motor-evacuation function of the intestine in patients with acute destructive appendicitis before surgery in comparison with patients of control group and recover in the postoperative period. Thus, the method of computerized phonoenterography is advisable to apply for the diagnosis of lower motor function of the intestine in patients with acute appendicitis, and in the early postoperative period in patients with acute destructive appendicitis for monitoring recovery of intestinal motility.

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Comparative analysis of the results of cochlear implantation under general and local anesthesiain patients with comorbid pathology

Consilium Medicum ◽

10.26442/20751753.2021.3.200603 ◽

2021 ◽

Vol 23 (3) ◽

pp. 250-255

Author(s):

Khassan M.A. Diab ◽

◽

Khassan M.A. Diab ◽

Nikolai A. Daikhes ◽

...

Keyword(s):

Hearing Loss ◽

Comparative Analysis ◽

General Anesthesia ◽

Local Anesthesia ◽

Postoperative Period ◽

Cochlear Implantation ◽

Early Postoperative Period ◽

Main Group ◽

Control Group ◽

Fourth Degree

The article is devoted to an urgent problem – the correction of hearing impairment in patients with concomitant diseases. The results of a comparative analysis of data from patients with somatic diseases who underwent cochlear implantation (CI) for severe to profound hearing loss hearing loss of the fourth degree and deafness under local and general anesthesia are presented. Materials and methods. On the basis of the National Medical Research Center for Otorhinolaryngology of the Federal Medical-Biological Agency of Russia, CI was performed under local anesthesia for 10 patients with concomitant diseases, which represented difficulties for the use of general anesthesia (main group). All patients in the preoperative stage precisely informed about each stage of the surgery and with the cue-cards (with questions) to maintain contact with them during CI. The control group consisted of 10 patients who underwent CI under general anesthesia. CI was performed according to a standard technique. After the operation, a survey of patients of both groups about subjective sensations during the operation and in the early postoperative period was carried out. Results. CI under local anesthesia takes an average of 18±5.2 min, taking into account the time of anesthesia, which is 15±5.3 min less than with general anesthesia (p<0.001). When performing CI under local anesthesia, clear thresholds for recording acoustic reflexes stapedial muscle are determined, since in this case the effect of muscle relaxants is excluded. Against the background of local anesthesia, the necessary effect was achieved rather quickly, there was no increase in blood pressure to high numbers, patients answered all the signs and questions by reading the information from the cue-cards. A survey of patients revealed a good tolerance to local anesthesia. The number of patients in the main group which had a complaints in the early postoperative period was less than in the control group (p<0.05). The duration of hospital staying in patients of the main group averaged 1.15 days (from 1 to 3 days), which is significantly less than in the control group – from 3 to 7 days, on average 4.05 days (p<0.05). When conducting CI under local anesthesia, none of the patients showed a destabilization of comorbidity pathology in the postoperative period. Conclusion. CI under local anesthesia in patients with concomitant pathology has several advantages over general anesthesia. The use of local anesthesia will increase the availability of CI for elderly comorbid patients and mitigate the risks of general anesthesia.

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The Effects of Vibration and Pressure Treatments in the Early Postoperative Period of Rhinoplasty

Aesthetic Surgery Journal ◽

10.1093/asj/sjz226 ◽

2019 ◽

Vol 40 (6) ◽

pp. 605-616 ◽

Cited By ~ 2

Author(s):

Süleyman Taş

Keyword(s):

Postoperative Period ◽

Early Postoperative Period ◽

Control Group ◽

Level Of Evidence ◽

Vibration Treatment ◽

The Face ◽

Anti Inflammatory ◽

Group 2 ◽

A Prospective Study ◽

Nasal Cast

Abstract Background The early postoperative period can be distressing for the patients undergoing rhinoplasty since edema and ecchymosis are common complications. Objectives To analyze the effects of the vibration and pressure treatments in the early postoperative period of rhinoplasty. Methods Sixty patients, who had undergone rhinoplasty, were randomized into 3 groups: group 1 (control group, n = 20) received classic nasal casting, group 2 (n = 20) received nasal cast with an elastic bandage to hold it on the face, and group 3 (n = 20) received vibration treatment in addition to that in group 2 following the rhinoplasty. They were evaluated preoperatively and postoperatively at 3 and 7 days in a prospective study. The postoperative edema and ecchymosis were scored by 2 independent surgeons. The postoperative pain was measured using the visual analog scale, and the necessity of anti-inflammatory medication (and the dose needed) and the cast comfort was questioned. The sebaceous activity of the nose skin was examined. A preoperative and postoperative seventh day sonographic study was performed to evaluate the tissue edema objectively. Results The pressure treatment decreased the edema and ecchymosis significantly compared with the control group. The vibration treatment minimized edema, ecchymosis, sebaceous activity of the nose skin, pain score, and the need for anti-inflammatory medication, and increased the cast comfort significantly compared with the other groups (P < 0.0001). Conclusions Rapid regression of edema and ecchymosis may be achieved using the vibrating nasal cast technique that may minimize patient discomfort, pain, and sebaceous activity following rhinoplasty. Level of Evidence: 1

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Acceptance of Illness after Surgery in Patients with Breast Cancer in the Early Postoperative Period

Polish Journal of Surgery ◽

10.1515/pjs-2016-0001 ◽

2015 ◽

Vol 87 (11) ◽

Cited By ~ 1

Author(s):

Andrzej Nowicki ◽

Elżbieta Krzemkowska ◽

Piotr Rhone

Keyword(s):

Breast Cancer ◽

Postoperative Period ◽

Early Period ◽

Conservative Surgery ◽

Early Postoperative Period ◽

Economic Situation ◽

White Collar Workers ◽

Acceptance Of Illness ◽

High Level ◽

Type Of Surgery

AbstractThe breast cancer is the most common cancer in women, both in Poland and in the world. Consequences entail a disruption in the physical, psychological and social functioning.was to assess the acceptance of illness by patients treated for breast cancer in the early postoperative period.The research was conducted on the group of 100 consecutive patients aged 32-80 years (median 56 years) who underwent surgery for breast cancer in the Centre of Oncology in Bydgoszcz w 2014 roku. 68 of women had mastectomy, 32 of women had conservative surgery. Polling was conducted in the early period after surgery. The original questionnaire containing closed questions the scale of acceptance of the disease (AIS) as well as mental adaptation to cancer (Mini-Mac) was used in the study.38% of patients had high acceptance of the disease, 48% averageand 14% had low acceptance. Patients after conservative surgery had a higher average values for the mental strategies to cope with the disease, for the fighting spirit (23.1), helplessness and hopelessness (13.5), positive revaluation (23), the patients had a lower average (16.5) in the strategy to absorb anxiety. Patients after conservative surgery had a higher average for constructive style (2.6) but lower for destructive style (1.5). High level of mental coping with the disease was observed in 53%of patients with constructive style and 4% of patients with destructive style. While, a low level of mental coping with the dosease was observed in 5% of patients with constructive style and 46% of patients with destructive style.Almost half of women after mastectomy or conservative surgery had an average acceptance of the disease. The disease was accepted best by educated women living in the cities, white-collar workers with a good economic situation. The following factors were affected the better management of the disease, in order: age, education, current occupation and economic situation, while the type of surgery did not affect better management. More than half of women, regardless of the type of surgery reflected the high level of constructive style.

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Anti-Vascular Endothelial Growth Factor Therapy as an Adjunct to Diabetic Vitrectomy

The Open Ophthalmology Journal ◽

10.2174/1874364102115010137 ◽

2021 ◽

Vol 15 (1) ◽

pp. 137-143

Author(s):

Mushfig Karimov ◽

Lala Akhundova

Keyword(s):

Diabetic Retinopathy ◽

Proliferative Diabetic Retinopathy ◽

Postoperative Period ◽

Early Postoperative Period ◽

Vitreous Cavity ◽

Control Group ◽

Diabetic Vitrectomy ◽

Clinically Significant ◽

Bevacizumab Injection

Introduction: The purpose of this work is to study the efficacy of the preoperative intravitreal administration of bevacizumab as an adjunct to vitrectomy in patients with Proliferative Diabetic Retinopathy (PDR). Methods: This retrospective comparative study was performed on 118 eyes (118 patients) with proliferative diabetic retinopathy (PDR), which underwent vitrectomy surgery at the Department of Diabetic Eye Disease at Zarifa Aliyeva National Ophthalmology Centre (Baku, Azerbaijan) in 2015-2019. The main group (the bevacizumab group) included 48 eyes with PDR that received intravitreal administration of bevacizumab (Avastin; Genentech Inc., USA) within one week before vitrectomy; the control group included 70 eyes that did not receive a bevacizumab injection for at least 3 months before the vitrectomy. The minimum follow-up was 12 months. Results: In both groups, complete retinal attachment after primary vitrectomy was achieved in all eyes (100%). Clinically significant intraoperative haemorrhage was observed in the preoperative bevacizumab injection group in 31.2% and the control group- 51.4%, p = 0.030. The preoperative bevacizumab injection reduced the risk of clinically significant haemorrhage by 2.3 times and the need for endodiathermy by 2.7 times (p = 0.031 and p = 0.024, respectively). Early vitreous cavity haemorrhage was observed in 15.0% in the bevacizumab group and in 35.5% in the control group (p = 0.038). The preoperative injection of bevacizumab before vitrectomy reduced the risk of vitreous cavity haemorrhage in the early postoperative period by 3.0 times (p = 0.036). Conclusion: The preoperative use of bevacizumab as an adjunct to diabetic vitrectomy can help reduce the incidence of intraoperative and early postoperative vitreous cavity haemorrhage, which leads to better functional results in the early postoperative period. Over the long-term follow-up period, the effect of the preoperative bevacizumab injections decreases.

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Diagnostics and treatment of abdominal complications after gynecological endoscopic operations

Reproductive health of woman ◽

10.30841/2708-8731.1.2021.229720 ◽

2021 ◽

Vol 1 ◽

pp. 75-79

Author(s):

Yu.P. Vdovichenko ◽

V.I. Boyko ◽

V.A. Terehov

Keyword(s):

Postoperative Complications ◽

Postoperative Period ◽

Diagnostic Laparoscopy ◽

Abdominal Cavity ◽

Early Postoperative Period ◽

Main Group ◽

Laparoscopic Technique ◽

Control Group ◽

Diffuse Peritonitis ◽

Abdominal Complications

The objective: to analyze the results of repeated laparoscopy in gynecological patients with suspected intraperitoneal postoperative complications.Materials and methods. The study involved 42 patients (mean age 46±11,3 years), in whom postoperative abdominal complications after surgical treatment of various gynecological diseases required repeated operations. Depending on the method of re-intervention, the patients were divided into 2 groups: the main group (n=20) – women who only used laparoscopy to correct postoperative complications; control (n=22) – women who were given indications for relaparotomy to correct postoperative complications during diagnostic laparoscopy. Relaparotomy was performed in 8 patients of the control group. All patients underwent a comprehensive examination using clinical, instrumental and laboratory research methods. The groups were homogeneous in terms of age and structure of operations performed on the pelvic organs, and statistically comparable.Results. During the study, the results of repeated laparoscopy of 34 gynecological patients with suspected intraperitoneal postoperative complications were analyzed. In all patients of the main group (47,6%), laparoscopy was revealed as the only and final method of treatment of postoperative complications, while in 7 women repeated relaparoscopy was used from 2 to 4 times, and in 13 women laparoscopy was performed once. In the control group (53,3%), 10 patients during diagnostic laparoscopy were exposed to indications for relaparotomy, in 4 patients the capabilities of the operating team and laparoscopic technique allowed performing some elements of the operation and completing it with a minilaparotomy approach, and 8 patients underwent relaparotomy immediately.Peritonitis and intraperitoneal bleeding prevail in the structure of early abdominal complications. The use of the video laparoscopic technique made it possible in 28,6% of patients with diffuse peritonitis to successfully eliminate the developed complication, eliminate its source and sanitize the abdominal cavity. Laparoscopic hemostasis was successfully performed in 7 patients.Compared with the standard, the use of video endoscopic technique allowed improving the indicators of diagnostic value: to increase the sensitivity level by 1,07 times, specificity by 1,39 times and diagnostic accuracy by 1,11 times.Conclusion. In general, in the early postoperative period, 47 relaparoscopies were performed for suspected complications, which is explained by programmed abdominal sanitization and the use of dynamic laparoscopy to control the course of intraperitoneal complications. Based on the analysis of the material under study, we proposed general indications and contraindications for relaparoscopy in the early postoperative period in order to diagnose and treat postoperative complications. Justifying each of the points, we were guided by the real possibilities of the method in general clinical practice, which in some cases are inferior in their effectiveness to relaparotomy.

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Comparison of Ondansetron and Granisetron for prevention of PONV following elective LUCS

Journal of the Bangladesh Society of Anaesthesiologists ◽

10.3329/jbsa.v20i2.3993 ◽

2009 ◽

Vol 20 (2) ◽

pp. 61-65 ◽

Cited By ~ 1

Author(s):

Md Raihan Uddin ◽

Lutful Aziz ◽

SN Samad Choudhury

Keyword(s):

Caesarean Section ◽

Spinal Anaesthesia ◽

Postoperative Period ◽

Elective Caesarean Section ◽

Study Groups ◽

Early Postoperative Period ◽

Control Group ◽

Group A ◽

Group B ◽

Oral Ondansetron

The aim of the study was to compare the antiemetic effects of oral ondansetron (8mg) and granisectron (2mg) for prevention of PONV following elective caesarean section. Ninety parturients scheduled for elective caesarean section under spinal anaesthesia were randomly allocated into three groups. Group A (n=30) were received vitamin tab, group B (n=30) parturients were received oral ondansectron (8mg) & group C (n=30) parturients were received oral granisetron (2mg). Anesthetic procedure was common to all groups. Emetic episodes in early postoperative period (1st 24 hrs.) were recorded and compared in different study groups. Emetic episodes were observed in six parturients (20%) in group A (control), 3 parturients in group B (3%) and 3 parturients in group C (3%). So to conclude, minimal emetic episodes were observed in early postoperative period in parturients who had received ondensetron or granisetron than the control group. Keywords: LUCS, PONV, Ondansetron, and Granisetron. Journal of BSA, Vol. 20, No. 2, July 2007 p.61-65

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Choice of surgical treatment for chronic composite hemorrhoid

Russian Military Medical Academy Reports ◽

10.17816/rmmar64952 ◽

2020 ◽

Vol 39 (3) ◽

pp. 27-31

Author(s):

Oleg A. Litvinov ◽

Evgeniy V. Zhitikhin ◽

Igor G. Ignatovich ◽

Hovannes A. Arutyunyan ◽

Artur G. Arustamov ◽

...

Keyword(s):

Postoperative Period ◽

Rating Scale ◽

Stage Iv ◽

Pain Syndrome ◽

Numeric Rating Scale ◽

Early Postoperative Period ◽

Control Group ◽

Scientific Center ◽

Cavernous Tissue ◽

Numeric Rating

A comparative analysis of the treatment of 142 patients operated on chronic hemorrhoid stage IIIIV has been passed by way of assess the results of using new version of hemorrhoidectomy. The age of patients ranged from 27 to 80 (mean age was 50.46.7). 86 (60.6%) patients were diagnosed with stage III chronic hemorrhoid, at 56 (39.4%) patients the stage IV. For this study patients were divided into basic and controlled groups. The basic group consisted of 73 (51.4%) patients that have had hemorrhoidectomy using our modification. There were 69 (48.6%) patients in control group that have been operated by MilliganMorgan method in second modify of State Scientific Center of Proctology using bipolar coagulator LigaSure. The level of pain was assessed in the early postoperative period by numeric rating scale. The patients had been operated by our method mentioned that the pain syndrome was less pronounced (3.2 against 4.9 balls), that required less painkillers in the early postoperative period. In the case of doing semicircle cuts on the border of anocutaneous crinkle and bringing down mucous membrane, the significant excision of the cavernous tissue doesnt lead to contraction of the anal canal by that reduces the number of functional disorders after hemorrhoidectomy (4 figs, 1 table, bibliography: 7 refs).

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Non-Conservative Therapy in the Prevention of Subepithelial Fibroplasia after LASEK Hypermetropia Correction

Ophthalmology in Russia ◽

10.18008/1816-5095-2018-2-200-206 ◽

2018 ◽

Vol 15 (2) ◽

pp. 200-206

Author(s):

S. A. Korotkikh ◽

A. E. Bogachev ◽

A. S. Shamkin

Keyword(s):

Dry Eye ◽

Postoperative Period ◽

Sodium Hyaluronate ◽

Early Postoperative Period ◽

Diagnostic Methods ◽

Dry Eye Syndrome ◽

Control Group ◽

Study Group ◽

Postoperative Therapy ◽

Significant Difference

The results of observation of patients who underwent vision eximerlaser correction by the LASEK method regarding medium degree of hyperopia were analyzed.Purpose:to investigate the severity of the «dry eye» syndrome and corneal subepithelial fibroplasia in patients after laser correction of hyperopia by the LASEK method, and their prevention by reducing the preservative action on the eye surface.Patients and methods.The study included 40 patients (76 eyes), aged 21–46 years (32.98 ± 1.79) who underwent LASEK surgery for moderate hyperopia (4.03 ± 0.38 D). Patients were divided into two groups: 1) control group (20 patients, 37 eyes) — postoperative therapy included the corneoprotector “Stilavit®” and the preparation of hyaluronic acid “Oksial®”, containing preservatives; 2) the study group (20 patients, 39 eyes) — postoperative therapy included the corneoprotector “Hilozar-comod®” and the artificial tear preparation “Hilo-comod®”, which did not contain reservatives. Ophthalmic examination included, in addition to standard diagnostic methods, the Norn test, the Schirmer test, the staining of the eye surface with lissamine green. In addition, a questionnaire was conducted on a modified OSDI questionnaire; there a section characterizing the quality of vision (section B) was removed.Results.The analysis of the obtained data showed that in the study group there was less pronounced “dry eye” syndrome at 3,6,12 months after the operation. The maximum difference in the indicators of the “dry eye” syndrome between the groups was at 3 and 6 months of the postoperative period. When evaluating corneal subepithelial fibroplasia, maximum attention was paid to the frequency and the intensity index. It was shown a significant difference in the intensity of the haze between the study group and the control group by 26.1 % at 3 months, by 62.2 % at 6 months and by 65.3 % 12 months after the operation. Conclusion.Nonconservative therapy with sodium hyaluronate and dexapanthenol in the early postoperative period and only sodium hydrolurate allows to reduce the severity of the dry eye syndrome after laser correction of hypermetropia and, as a result, to reduce the intensity of haze development by 65.3 %, and its frequency on 11,5 %.

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