Familial Mediterranean Fever (FMF), Female and Male Fertility: Literature Review

2021 ◽  
pp. 3-11
Author(s):  
П.О. Соцкий
Keyword(s):  
Familial Mediterranean Fever ◽  
Male Fertility ◽  
Eastern Mediterranean ◽  
Reproductive Function ◽  
Peritoneal Adhesion ◽  
The Past ◽  
The World ◽  
Mediterranean Fever ◽  
Testicular Insufficiency ◽  
The Relationship

Семейная средиземноморская лихорадка (CCЛ) - моногенное наследственное аутовоспалительное заболевание, характеризующееся периодически повторяющимися приступами лихорадки, серозитами разной локализации, артритами, эризипелоидоподобным высыпанием. Хотя ССЛ болеют преимущественно представители популяций восточно-средиземноморского происхождения (турки, армяне, арабы, евреи-сефарды), в наши дни болезнь регистрируется по всему миру, что связано с непрерывными миграционными процессами. Потенциальные осложнения ССЛ (фиброз и амилоидоз) и их лечение колхицином могут повлиять на репродуктивную систему больных либо путем обструкции маточных труб, либо через избыточное образование дефектных сперматозоидов и ооцитов, либо вследствие овариальной/тестикулярной недостаточности. Амилоидоз с преимущественным отложением амилоида в яичниках и яичках может приводить к женскому и мужскому бесплодию. У мужчин колхицин в редких случаях индуцирует олиго/азооспермию. У женщин основными причинами бесплодия в прошлом считались дисовуляция и перитонеальная адгезия. В последние годы ситуация с фертильностью значительно улучшилась благодаря применению колхицина. В обзоре обобщается текущая информация о взаимосвязи женской и мужской фертильности с ССЛ и приемом колхицина; излагаются современные подходы к восстановлению репродуктивной функции при бесплодии. Акцент сделан на аспектах безопасности терапии, основные положения которой представлены в клинических рекомендациях по лечению ССЛ Европейской антиревматической лиги (EULAR,2016). Familial Mediterranean fever (FMF) is a monogenic inherited autoinflammatory disease characterized by recurrent episodes (attacks) of fever, serositis of different localization, arthritis, erysipelaslike rashes. Eastern Mediterranean persons (especially Turks, Armenians, Arabs, Sephardic Jews) are most frequently affected. Nowadays the disease is registered throughout the world because of migration processes. Potential complications of FMF (fibrosis and amyloidosis) and their treatment with colchicine may affect the reproductive system either by salpinx obstruction causing mechanical infertility, or by excessive formation of defective sperm and oocytes, either due to ovarian /testicular insufficiency. Amyloidosis can lead to female and male infertility with amyloid preponderance in the ovaries and testicles. Colchicine rarely induces oligo/ azoospermia in men. In women, disovulation and peritoneal adhesion were the main causes of infertility in the past. In recent years, the fertility situation has improved considerably due to the use of colchicine. The review summarizes current information on the relationship between female and male fertility with FMF and colchicine; modern approaches to restoring reproductive function in infertility are outlined. The focus is on the aspects of the safety of therapy, the main provisions of which are presented in the clinical recommendations for treatment of the FMF of the European Anti-Rheumatic League (EULAR, 2016).

IV.—The Geological Development, Descent and Distribution of the Mammalia

1893 ◽  
Vol 10 (9) ◽  
pp. 401-412 ◽  
Author(s):  
Karl A. von Zittel
Keyword(s):  
South America ◽  
The Past ◽  
Limited Experience ◽  
The World ◽  
Relationship Of ◽  
North And South America ◽  
The Relationship ◽  
North And South ◽  
Animal World

In a spirited treatise on the ‘Origin of our Animal World’ Prof. L. Rütimeyer, in the year 1867, described the geological development and distribution of the mammalia, and the relationship of the different faunas of the past with each other and with that now existing. Although, since the appearance of that masterly sketch the palæontological material has been, at least, doubled through new discoveries in Europe and more especially in North and South America, this unexpected increase has in most instances only served as a confirmation of the views which Rutimeyer advanced on more limited experience. At present, Africa forms the only great gap in our knowledge of the fossil mammalia; all the remaining parts of the world can show materials more or less abundantly, from which the course followed by the mammalia in their geological development can be traced with approximate certainty.

Number of Siblings in Childhood, Social Outcomes in Adulthood

2019 ◽  
Vol 41 (2) ◽  
pp. 212-234
Author(s):  
Joseph J. Merry ◽  
Donna Bobbitt-Zeher ◽  
Douglas B. Downey
Keyword(s):  
Conflict Management ◽  
Negative Association ◽  
Social Outcomes ◽  
Past Century ◽  
Adult Health ◽  
Growing Up ◽  
The Past ◽  
National Longitudinal Study ◽  
The World ◽  
The Relationship

In many parts of the world, fertility has declined in important ways in the past century. What are the consequences of this demographic change? Our study expands the empirical basis for understanding the relationship between number of siblings in childhood and social outcomes among adults. An important recent study found that for each additional sibling an individual grows up with, the likelihood of divorce as an adult declines by 3%. We expand this work by (a) determining whether the original pattern replicates in the National Longitudinal Study of Adolescent to Adult Health and (b) extending the analysis beyond divorce to consider whether growing up with siblings is related to prosocial adult behaviors (relationships with parents, friends, and views on conflict management with one’s partner). Our results confirm a negative association between number of siblings and divorce in adulthood. We find mixed results related to other prosocial adult behaviors.

scholarly journals Poetic Storytelling in Contemporary Photography. Relation to Nature and the Poesis of Everyday Life in Works of Selected Artist in Iceland and Other Nordic Countries

Arts ◽  
2020 ◽  
Vol 9 (4) ◽  
pp. 129
Author(s):  
Sigrún Alba Sigurðardóttir
Keyword(s):  
Everyday Life ◽  
Nordic Countries ◽  
The Other ◽  
The Past ◽  
The World ◽  
Phenomenological Perspective ◽  
The One ◽  
Climate Crisis ◽  
The Relationship ◽  
Narrative Medium

The past 20 years have seen a shift in Icelandic photography from postmodern aesthetics towards a more phenomenological perspective that explores the relationship between subjective and affective truth on the one hand, and the outside world on the other hand. Rather than telling a story about the world as it is or as the photographer wants it to appear, the focus is on communicating with the world, and with the viewer. The photograph is seen as a creative medium that can be used to reflect how we experience and make sense of the world, or how we are and dwell in the world. In this paper, I introduce the theme of poetic storytelling in the context of contemporary photography in Iceland and other Nordic Countries. Poetic storytelling is a term I have been developing to describe a certain lyrical way to use a photograph as a narrative medium in reaction to the climate crisis and to a general lack of relation to oneself and to the world in times of increased acceleration in the society. In my article I analyze works by a few leading Icelandic photographers (Katrín Elvarsdóttir, Heiða Helgadóttir and Hallgerður Hallgrímsdóttir) and put them in context with works by artists from Denmark (Joakim Eskildsen, Christina Capetillo and Astrid Kruse Jensen), Sweden (Helene Schmitz) and Finland (Hertta Kiiski) artists within the frame of poetic storytelling. Poetic storytelling is about a way to use a photograph as a narrative medium in an attempt to grasp a reality which is neither fully objective nor subjective, but rather a bit of both.

scholarly journals Rethinking the message of the church in the 21st century: An amalgamation between science and religion

2019 ◽  
Vol 75 (4) ◽  
Author(s):  
Dirk G. Van der Merwe
Keyword(s):  
20Th Century ◽  
21St Century ◽  
Science And Religion ◽  
Western World ◽  
The Past ◽  
The Bible ◽  
The World ◽  
The Relationship ◽  
The Church ◽  
Theological Training

Throughout its history, Christianity has stood in a dichotomous relation to the various philosophical movements or eras (pre-modernism, modernism, postmodernism and post-postmodernism) that took on different faces throughout history. In each period, it was the sciences that influenced, to a great extent, the interpretation and understanding of the Bible. Christianity, however, was not immune to influences, specifically those of the Western world. This essay reflects briefly on this dichotomy and the influence of Bultmann’s demythologising of the kerygma during the 20th century. Also, the remythologising (Vanhoozer) of the church’s message as proposed for the 21st century no more satisfies the critical Christian thinkers. The relationship between science and religion is revisited, albeit from a different perspective as established over the past two decades as to how the sciences have been pointed out more and more to complement theology. This article endeavours to evoke the church to consider the fundamental contributions of the sciences and how it is going to incorporate the sciences into its theological training and message to the world.

scholarly journals THE PREVALENCE OF CELIAC DISEASE AMONG PATIENTS WITH FAMILIAL MEDITERRANEAN FEVER

2015 ◽  
Vol 52 (1) ◽  
pp. 55-58 ◽  
Author(s):  
Sedat IŞIKAY ◽  
Nurgül IŞIKAY ◽  
Halil KOCAMAZ
Keyword(s):  
Celiac Disease ◽  
Familial Mediterranean Fever ◽  
Tissue Transglutaminase ◽  
Control Group ◽  
Marsh Type ◽  
Significant Difference ◽  
Healthy Control ◽  
Mediterranean Fever ◽  
Relationship Of ◽  
The Relationship

Background Familial Mediterranean Fever and celiac disease are both related to auto-inflammation and/or auto-immunity and they share some common clinical features such as abdominal pain, diarrhea, bloating and flatulence. Objectives We aimed to determine the association of these two diseases, if present. Methods Totally 112 patients diagnosed with Familial Mediterranean Fever and 32 cases as healthy control were included in the study. All participants were examined for the evidence of celiac disease, with serum tissue transglutaminase IgA levels (tTG IgA). Results Totally 144 cases, 112 with Familial Mediterranean Fever and 32 healthy control cases were included in the study. tTG IgA positivity was determined in three cases with Familial Mediterranean Fever and in one case in control group. In that aspect there was no significant difference regarding the tTG IgA positivity between groups (P=0.81). Duodenum biopsy was performed to the tTG IgA positive cases and revealed Marsh Type 3b in two Familial Mediterranean Fever cases and Marsh Type 3c in the other one while the biopsy results were of the only tTG IgA positive case in control group was Marsh Type 3b. In HLA evaluation of the celiac cases; HLA DQ2 was present in two celiac cases of the Familial Mediterranean Fever group and in the only celiac case of the control group while HLA DQ8 was present in one celiac case of the Familial Mediterranean Fever group. Conclusions We did not determine an association of Familial Mediterranean Fever with celiac disease. Larger studies with subgroup analysis are warranted to determine the relationship of these two diseases.

A first preliminary study of the shallow water sponge fauna from Cyprus Island (Eastern Mediterranean)

Zootaxa ◽  
2018 ◽  
Vol 4450 (5) ◽  
pp. 594
Author(s):  
COSTA GABRIELE ◽  
GIUSSANI VALENTINA ◽  
KLETOU DEMETRIS ◽  
KLEITOU PERIKLIS ◽  
PANSINI MAURIZIO ◽  
...  
Keyword(s):  
Shallow Water ◽  
Mediterranean Sea ◽  
Eastern Mediterranean ◽  
Sponge Species ◽  
Commercial Importance ◽  
The Past ◽  
Number Of Species ◽  
Mediterranean Areas ◽  
The World ◽  
Preliminary Study

Currently, more than 8,500 valid sponge species are reported in the World Porifera Database (http://www.marinespecies.org/porifera/) (van Soest et al. 2018). The Mediterranean Sea sponge fauna, counting almost 700 species, is one of the best documented in the world (Pronzato 2003; Pansini et al. 2011; van Soest et al. 2018) but the eastern part of the basin is by far less studied, in comparison with other Mediterranean areas (Pansini et al. 2000; Voultsiadou & Vafidis 2004; Topaloğlu & Evcen 2014). A small number of species, mainly belonging to the cosmopolitan genus Spongia (Dictyoceratida), are commonly used as bath sponges. Aim of this work is to provide further information on Cyprus Island sponges in general and on species that had commercial importance in the past. 

The Time Perception in Contemporary

2017 ◽  
Vol 41 (S1) ◽  
pp. S717-S717
Author(s):  
D.F. Burgese ◽  
D.P. Bassitt ◽  
D. Ceron-Litvoc ◽  
G.B. Liberali
Keyword(s):  
New Technologies ◽  
New Technology ◽  
The Self ◽  
The Other ◽  
The Past ◽  
The World ◽  
Relationship Processes ◽  
Competing Interest ◽  
New Phenomena ◽  
The Relationship

With the advent of new technologies, the man begins to experience a significant change in the perception of the other, time and space. The acceleration of time promoted by new technology does not allow the exercise of affection for the consolidation of ties, relations take narcissists hues seeking immediate gratification and the other is understood as a continuation of the self, the pursuit of pleasure. It is the acceleration of time, again, which leads man to present the need for immediate, always looking for the new – not new – in an attempt to fill an inner space that is emptied. The retention of concepts and pre-stressing of temporality are liquefied, become fleeting. We learn to live in the world and the relationship with the other in a frivolous and superficial way. The psychic structure, facing new phenomena experienced, loses temporalize capacity and expand its spatiality, it becomes pathological. Post-modern inability to retain the past, to analyze the information received and reflect, is one of the responsible for the mental illness of today's society. From a temporality range of proper functioning, the relationship processes with you and your peers will have the necessary support to become viable and healthy.Disclosure of interestThe authors have not supplied their declaration of competing interest.

Dogs

2020 ◽  
Keyword(s):  
Lived Experiences ◽  
Domestic Dogs ◽  
Archaeological Research ◽  
Human Interactions ◽  
The Past ◽  
Theoretical Approaches ◽  
The World ◽  
History Of ◽  
The Many ◽  
The Relationship

The relationship between humans and dogs has garnered considerable attention within archaeological research around the world. Investigations into the lived experiences of domestic dogs have proven to be an intellectually productive avenue for better understanding humanity in the past. This book examines the human-canine connection by moving beyond asking when, why, or how the dog was domesticated. While these questions are fundamental, beyond them lies a rich and textured history of humans maintaining a bond with another species through cooperation and companionship over thousands of years. Diverse techniques and theoretical approaches are used by authors in this volume to investigate the many ways dogs were conceptualized by their human counterparts in terms of both their value and social standing within a variety of human cultures across space and time. In this way, this book contributes a better understanding of the human-canine bond while also participating in broader anthropological discussions about how human interactions with domesticated animals shape their practices and worldviews.

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