scholarly journals Synthesis and Evaluation of Cyclic Sulfite Diesters as Sulfur Dioxide (SO2) Donors

2019 ◽  
Author(s):  
Satish Malwal ◽  
Kundansinghsingh Pardeshi ◽  
Harinath Chakrapani

<div>Although sulfur dioxide (SO<sub>2</sub>) finds widespread use in the food industry as its hydrated form, sulfite, a number of aspects of SO<sub>2 </sub>biology remain to be completely understood. Among the tools available for intracellular enhancement of SO<sub>2</sub>, most suffer from poor cell permeability and a lack of control over SO<sub>2</sub> release. We report 1,2-cyclic sulfite diesters as a new class of reliable SO<sub>2 </sub>donors that dissociate in buffer through a nucleophilic displacement to produce SO<sub>2 </sub>with tuneable release profiles. We provide data in support of the suitability of these SO<sub>2 </sub>donors to enhance intracellular levels of SO<sub>2 </sub>at an efficiency superior to sodium bisulfite, the most commonly used SO<sub>2</sub> donor for cellular studies.</div>

2019 ◽  
Author(s):  
Satish Malwal ◽  
Kundansinghsingh Pardeshi ◽  
Harinath Chakrapani

<div>Although sulfur dioxide (SO<sub>2</sub>) finds widespread use in the food industry as its hydrated form, sulfite, a number of aspects of SO<sub>2 </sub>biology remain to be completely understood. Among the tools available for intracellular enhancement of SO<sub>2</sub>, most suffer from poor cell permeability and a lack of control over SO<sub>2</sub> release. We report 1,2-cyclic sulfite diesters as a new class of reliable SO<sub>2 </sub>donors that dissociate in buffer through a nucleophilic displacement to produce SO<sub>2 </sub>with tuneable release profiles. We provide data in support of the suitability of these SO<sub>2 </sub>donors to enhance intracellular levels of SO<sub>2 </sub>at an efficiency superior to sodium bisulfite, the most commonly used SO<sub>2</sub> donor for cellular studies.</div>


Author(s):  
В.О. ГОРОДЕЦКИЙ ◽  
С.О. СЕМЕНИХИН ◽  
Н.М. ДАИШЕВА ◽  
Н.И. КОТЛЯРЕВСКАЯ

Для увеличения производительности сахарного завода без существенных финансовых затрат можно использовать технологическую схему вывода сиропа на длительное хранение с последующей его переработкой в межсезонье. Одним из недостатков такой технологической схемы является риск микробиологической обсемененности сиропа, для снижения которой отечественные исследователи предлагают обработку электромагнитными полями. Однако, на наш взгляд, обработка сиропа сульфитсодержащими реагентами более безопасна и менее энергоемка. Проведены лабораторные исследования, направленные на снижение микробиологической обсемененности сиропа при выводе его на хранение. Объектом исследований был полученный в лабораторных условиях концентрированный сироп с содержанием сухих веществ 67%, который делили на три образца по 300 мл каждый. Контрольный образец сиропа оставляли без обработки, образец 1 обрабатывали сернистым ангидридом до рН 7,3–7,5, образец 2 – раствором бисульфита натрия в количестве 0,01% к массе образца. После этого все три образца подвергали подщелачиванию 1 н раствором NaOH до pH 9,15 и хранили в течение 100 сут при комнатной температуре. По окончанию срока хранения в образцах сиропа определяли микробиологические показатели и содержание редуцирующих веществ. Установлено, что предварительная обработка сиропа, направляемого на длительное хранение, сульфитсодержащими реагентами способствует достаточно эффективному снижению количества мезофильных аэробных и факультативно-анаэробных микроорганизмов и плесеней. Наибольший эффект снижения наблюдается при обработке сиропа сернистым ангидридом: на 69% снижается показатель микробиальной обсемененности и на 58% количество плесеней по сравнению с необработанным сиропом. При обработке сиропа бисульфитом натрия снижение составило 31 и 33% соответственно. Степень предотвращения накопления редуцирующих веществ при обработке сиропа сернистым ангидридом составила 18,8%, а при обработке бисульфитом натрия – 11,5%. Снижение микробиальной обсемененности сиропа при выводе его на длительное хранение будет способствовать снижению потерь сахарозы. To increase the productivity of the sugar factory without significant financial costs, you can use a technological scheme for the withdrawal of thick juice for long-term storage with its subsequent processing in the off-season. One of the disadvantages of such a technological scheme is the risk of microbiological contamination of the thick juice, to reduce which domestic researchers offer treatment with electromagnetic fields. However, in our opinion, the treatment of thick juice with sulfite-containing reagents is safer and less energy intensive. Laboratory studies aimed at reducing the microbiological contamination of the thick juiceduring its storage were carried out. The object of research was a concentrated thick juice obtained under laboratory conditions with a dry matter content of 67%, which was divided into three samples of 300 ml each. The control sample of the thick juice was left untreated, sample 1 was treated with sulfur dioxide to a pH of 7,3–7,5, sample 2 – with a solution of sodium bisulfite in an amount of 0.01% by weight of the sample. After that, all three samples were alkalized with 1 n NaOH solution to pH 9,15 and stored for 100 days at room temperature. At the end of the shelf life, microbiological parameters and the content of reducing substances were determined in the thick juice samples. It was found that the pretreatment of thick juice sent for long-term storage with sulfite-containing reagents contributes to a sufficiently effective reduction in the number of mesophilic aerobic and facultative anaerobic microorganisms and molds. The greatest reduction effect is observed when the thick juice is treated with sulfurous anhydride: the indicator of microbial contamination is reduced by 69% and the number of molds is reduced by 58% compared to untreated thick juice. When treating the syrup with sodium bisulfite, the reduction was 31 and 33% respectively. The degree of prevention of the accumulation of reducing substances when treating the thick juice with sulfur dioxide was 18,8%, and when treating with sodium bisulfite – 11,5%. Reducing the microbial contamination of the thick juicewhen it is taken out for long-term storage will help to reduce the loss of sucrose.


Chemosphere ◽  
2012 ◽  
Vol 89 (5) ◽  
pp. 579-584 ◽  
Author(s):  
Ziqiang Meng ◽  
Zhenhua Yang ◽  
Junling Li ◽  
Quanxi Zhang

Antibiotics ◽  
2020 ◽  
Vol 9 (9) ◽  
pp. 593
Author(s):  
Chengjun Shan ◽  
Han Wu ◽  
Jianzhong Zhou ◽  
Wenjing Yan ◽  
Jianhao Zhang ◽  
...  

In this paper, Lactocin C-M2(C-M2) was used together with a new non-thermal technology, non-thermal plasma sterilization (NTPS), to inactive the putrefactive bacteria Morganella sp. wf-1 isolated from aquatic foods. The mechanism underlining the action mode of C-M2 and NTPS was investigated, revealing that the bacteriocin and NTPS had synergistic effects on the disinfection of Morganella sp. wf-1. Compared with the bacteria cells treated by only C-M2 or NTPS, the plasmolysis of cells treated by C-M2 and NTPS was to a larger extent. Moreover, the cell permeability and the contents of UV-absorbing compounds and K+ released from the intra-cells was significantly higher for the C-M2 + NTPS treated cells than the others (p < 0.05), and conversely was the SFA/UFA ratio (p < 0.05). The results on DNA damage showed that, 8-hydroxy-2′-deoxyguanosine(8-OHdG) content in C-M2 + NTPS treated cells was approximately 7 -fold and 2.5-fold greater than those in the C-M2- and NTPS-treated cells, respectively, indicating furthermore the eventual rupture of Morganella sp. wf-1 cells. The results showed the potential of the application of the bacteriocin and NTPS in the food industry.


2020 ◽  
Vol 7 ◽  
Author(s):  
Mojtaba Yousefi ◽  
Nasim Khorshidian ◽  
Hedayat Hosseini

One of the most important challenges in the food industry is to provide healthy and safe food. Therefore, it is not possible to achieve this without different processes and the use of various additives. In order to improve safety and extend the shelf life of food products, various synthetic preservatives have been widely utilized by the food industry to prevent growth of spoilage and pathogenic microorganisms. On the other hand, consumers' preference to consume food products with natural additives induced food industries to use natural-based preservatives in their production. It has been observed that herbal extracts and their essential oils could be potentially considered as a replacement for chemical antimicrobials. Antimicrobial properties of plant essential oils are derived from some main bioactive components such as phenolic acids, terpenes, aldehydes, and flavonoids that are present in essential oils. Various mechanisms such as changing the fatty acid profile and structure of cell membranes and increasing the cell permeability as well as affecting membrane proteins and inhibition of functional properties of the cell wall are effective in antimicrobial activity of essential oils. Therefore, our objective is to revise the effect of various essential oils and their bioactive components against Listeria monocytogenes in meat and poultry products.


2020 ◽  
Vol 3 ◽  
Author(s):  
Nuraslina Zainal Abidin ◽  
Firdaus Fanny Putera Perdana

Despite rooted from Islamic needs, Halal certification also attracts both Muslims and non-Muslims. In fact, the non-Muslim players are the ones dominating the industry. It is widely known that Halal food chain is quite vulnerable due to complications in maintaining Halal integrity, the necessity to prevent doubtful materials, lack of control of food norms, and the importance to retain high quality. The presence of Halal certification is a form of consumer protection and therefore, the integrity of Halal certification must be carefully monitored. There are some Halal violation cases and this can potentially affect the reputation of the Halal food products. Therefore, it is important to develop a system that integrates a verifiable, open, and safe shared database that is not run by a centralized operator. Blockchain technology is the one that offers such. The study presents a framework for blockchain technology for Halal product verification for manufactured food products. The results are desired to help the food industry players in maintaining a system that can improve the transparency and the integrity of their Halal food chain. The system also intends to ensure the affordability and accessibility of Halal certification for as many industry players as possible as blockchain technology is believed to remove the complications in the certification process and reduce paperwork related cost.


Author(s):  
L. A. Nikolaeva ◽  
◽  
E. M. Khusnutdinova ◽  

It is proposed to purify industrial gas emissions from sulfur dioxide by the adsorption method. Waste from the power industry - sludge from the chemical water treatment of Kazan CHPP-1 - was used as an adsorption material. Its chemical composition is presented. Experimental studies of a new sorption material based on energy waste for gas purification from sulfur dioxide have been carried out. The kinetic dependence and isotherm of the adsorption process are obtained. The mechanism of the process of adsorption of sulfur dioxide by sorption material at different temperatures has been studied. The Gibbs free energy, differential heat, and activation energy of adsorption are determined. The economic and environmental impact of modernization of procedure for cleaning gas emissions from sulfur dioxide in sodium bisulfite production at JSC “Chemical factory named after L.Ya. Karpov” was measured.


2020 ◽  
Vol 28 (4) ◽  
pp. 397-407
Author(s):  
Larisa A. Nikolaeva ◽  
Elvira M. Khusnutdinova

Chemical industry enterprises are the main environmental pollutants that cause environmental problems. This is due to the production technology and the toxicity of some substances. In this paper, it is proposed to purify the gas emissions at the JSC Karpov Chemical Plant formed during the production of sodium bisulfite from sulfur dioxide by the adsorption method. As a sorption material, a modified energy waste - carbonate sludge from the chemical water treatment plant of the Naberezhnye Chelny CHPP - was used. The technological characteristics of the granular sorption material are presented. A batch adsorber with a fixed layer of granular sorption material is calculated. The modernization of the technological scheme for cleaning gas emissions from sulfur dioxide of the production line of sodium bisulfite at JSC Chemical Plant named after L.Ya. Karpov is proposed. The calculation of the prevented environmental damage and the economic effect of the modernization of the technological scheme is made.


ChemBioChem ◽  
2020 ◽  
Vol 21 (8) ◽  
pp. 1201-1205
Author(s):  
Satish R. Malwal ◽  
Kundansingh A. Pardeshi ◽  
Harinath Chakrapani

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