Arterial hypertension in young men, officers of land forces: psychophysiological peculiarities

The authors have studied heart rhythm variability at rest and with cognitive loading, types of coronary behavior and reactive and personal anxiety in 86 men of young age, officers of the land forces. 52 of them had hypertensive disease (HD) of I–II stage. 34 men had normal arterial blood pressure. Patients with HD in comparison with normotensive men turned out to have additional risk factors accompanied arterial hypertension. They were hypersympaticotonia, high level of personal anxiety and coronary behavior type A.

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SPECIFICS OF ARTERIAL HYPERTENSION DEVELOPMENT IN PENITENTIARY STRESS CIRCUMSTANCES

Russian Journal of Cardiology ◽

10.15829/1560-4071-2018-4-25-31 ◽

2018 ◽

pp. 25-31

Author(s):

E. V. Dyuzheva ◽

S. B. Ponomarev

Keyword(s):

Arterial Hypertension ◽

Wave Spectrum ◽

Heart Rhythm ◽

Heart Rhythm Variability ◽

Young Males ◽

Sympathetic Modulation ◽

Situational Anxiety ◽

And Gender ◽

Hypertension Development ◽

High Level

Aim. To reveal the specifics of arterial hypertension (AH) development under the circumstances of penitentiary stress.Material and methods. Totally, 107 patients included, among the persons first time imprisoned, comparable by age and gender — almost healthy young males 25-36 y. o. The relation studied, of psychological test and 24-hour blood pressure (BP) profile and Holter ECG, as heart rate variablity, in three groups of participants formed depending on the duration of imprisonment.Results. It was found that psychoemotional state during the first month of imprisonment is characterized by a high level of situational, personality anxiety with predominant depressive symptomatic. This is followed by heart conduction and rhythm pathology. With the time of imprisonment, level of anxiety and depression declines. Also, heart rhythm variability analysis shows significant decrease of value of LF (%) and predomination of VLF (%) in the wave spectrum. The parameters of 24-hour BP show a significant increase of BP at later periods of imprisonment. Daytime BP level shows direct relation with the parameter “duration of imprisonment”, and nocurnal BP — with the level of situational anxiety.Conclusion. Under the circumstances of penitentiary stress, one of the revealed mechanism of AH development is weakening of sympathetic modulation of vegetative innervation of the heart and decline of baroreflectory sensitivity. Increase of the duration of imprisonment and of the level of situational anxiety are the specific factors of penitentiary circumstances that influence AH development in young clinically healthy men.

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Оценка экстракраниального и интракраниального артериального кровобращения у пациентов молодого возраста с артериальной гипертонией, сопровождающейся мигренью или головной болью напряжения

Dalʹnevostočnyj medicinskij žurnal ◽

10.35177/1994-5191-2020-1-28-36 ◽

2020 ◽

pp. 28-36

Keyword(s):

Blood Pressure ◽

Blood Flow ◽

Arterial Hypertension ◽

Flow Resistance ◽

Posterior Cerebral Artery ◽

Tension Type Headache ◽

Left Vertebral Artery ◽

Hypertensive Disease ◽

Arterial Blood ◽

Type Headache

The authors studied the state of blood ﬂow in the system of arterial vessels of the head and neck in 30 patients with hypertensive disease (HD) stage I, arterial hypertension (AH), 1st degree – in 26 (86,7 %) and 2nd degree – in 4 (13,3 %) people, with comorbid migraine (M) – in 14 (46,7 %) people and tension-type headache (TTH) – in 16 (53,3 %) people, triplex scanning of extra- and intracranial vessels was performed and measurement of arterial blood pressure was conducted. In patients with AH and comorbid M or TTH, decrease in the velocity and volume parameters of blood ﬂow in the arteries at the extracranial and intracranial level, as well as increase in the indexes of blood ﬂow resistance in comparison with the control, were revealed. In patients with AH and TTH, blood ﬂow in the left vertebral artery and right posterior cerebral artery was lower than in patients with AH and M.

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Thyroid dysfunction and cardiovascular risk factors in Bulgarian adults

Open Medicine ◽

10.2478/s11536-013-0235-9 ◽

2013 ◽

Vol 8 (6) ◽

pp. 742-748 ◽

Cited By ~ 1

Author(s):

Alexander Shinkov ◽

Anna-Maria Borissova ◽

Roussanka Kovatcheva ◽

Jordan Vlahov ◽

Lilia Dakovska ◽

...

Keyword(s):

Risk Factors ◽

Cardiovascular Risk ◽

Arterial Hypertension ◽

Cardiovascular Risk Factors ◽

Thyroid Function ◽

Thyroid Dysfunction ◽

Lipid Status ◽

Arterial Blood ◽

Bulgarian Population ◽

New Diagnosis

AbstractThe aim of this study was to determine the prevalence of thyroid dysfunction and its association with cardiovascular risk factors in an adult Bulgarian population. 2402 subjects were studied, 1347 female, 20–94y (median: 48.0y) and 1055 male, 20–91y (median: 45.5y). Body weight, height, waist circumference, arterial blood pressure, TSH, FT4 and lipids were measured. Known hypothyroidism was reported by 53 subjects (2.2%) and hyperthyroidism by 20 (0.8%). New hypothyroidism was found in 98 (4.1%), [subclinical (3.2%), overt (0.9%)]. New hyperthyroidism was found in 68 (2.9%), [subclinical (2.5%), overt (0.4%)]. New diagnosis of hypothyroidism and hyperthyroidism was entered in 84% and 87% in male subjects and 60% and 65% in the females respectively. Arterial hypertension was present in 40% of the women and in 47% of the men (p<0.001) and was more prevalent in hypothyroidism. Abdominal obesity and dyslipidemia were more prevalent in males and hypothyroid subjects. Arterial hypertension depended on age, gender and lipid status but not on thyroid function. CHD history depended on thyroid function and age. Conclusion: Most cases of thyroid dysfunction were undiagnosed, especially in the males. CV risk factors were more prevalent in the males with thyroid dysfunction a major determinant of CHD, but not hypertension.

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HEART RHYTHM DISORDERS IN NEW-BORNS AND INFANTS: CLINICAL COURSE AND PERINATAL RISK FACTORS OF ARRHYTHMIAS APPEARANCE

Bulletin of Siberian Medicine ◽

10.20538/1682-0363-2013-6-31-37 ◽

2013 ◽

Vol 12 (6) ◽

pp. 31-37

Author(s):

I. A. Kovalyov ◽

S. Yu. Usenkov ◽

L. I. Svintsova

Keyword(s):

Risk Factors ◽

Natural History ◽

Structural Changes ◽

Clinical Course ◽

Heart Rhythm ◽

Perinatal Period ◽

Heart Rhythm Variability ◽

Central Nervous System Damage ◽

Heart Rhythm Disorders

Clinical course, prognosis and mechanisms of separate forms of heart rhythm disorders in children differ from those in adults. Especially, it refers to new-borns and infants whose conduction system differs by functional and morphologic immaturity. In connection with it, the assessment of natural history of heart rhythm disorders, occurred in a perinatal period, and determination of risk factors of arrhythmia appearance in infants are of some interest. 88 newborns took part in the study. The patients were involved by continuous sampling technique. Risk factors, occurred in a perinatal period and potentially influenced on development of heart rhythm disorders, were assessed. In our study we took biological, gynecologic and obstetric history, data of gestation and delivery course, early and late neonatal period, early infancy, Echo, neurosonography, Holter monitoring with determination of heart rhythm variability, and determined thyroid hormonal status. Maximum specific gravity had extrasystoles – 32.4% – in the structure of idiopathic arrhythmias in infants. Heart rhythm disorders with natural history were kept at six months of life only in 5,4% of children. Persistence of arrhythmias was marked during one year only for WPW syndrome. Heart rhythm disorders are often marked significantly in children whose mothers had acute respiratory disease during the pregnancy, or if the children were born from the first pregnancy, had the signs of central nervous system damage syndromes in an early perinatal period (arrest, intracranial hypertension, convulsive disorder). Disorders of autonomic imbalance of cardiac function and peculiarities of hemodynamics of pulmonary circulation contribute significantly into appearance and persistence of all types of arrhythmias. On the whole, the prognosis of heart rhythm disorders, occurred in the perinatal period, without organic and structural changes of myocardium is favorable. The exclusion can be made for congenital atrioventricular block and some types of supraventricular tachycardia which are not responded to treatment.

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Anxiety and depressive disorders in children of early adolescence

Biomedical and Biosocial Anthropology ◽

10.31393/bba36-2019-07 ◽

2020 ◽

pp. 41-46

Author(s):

Yu. N. Lysytsia ◽

S. V. Rymsha

Keyword(s):

Risk Factors ◽

Depressive Symptoms ◽

Early Adolescence ◽

Depressive Disorders ◽

Severe Depression ◽

Boarding School ◽

Low Level ◽

Situational Anxiety ◽

Personal Anxiety ◽

High Level

The purpose of the work is to investigate the screening frequency of anxiety and depressive disorders and their manifestations in young adolescents to determine risk factors and develop measures for their prevention. Anxiety testing was conducted for 313 students of educational institutions of the Khmelnitsky region aged 10-14 years: 156 (49.8 %) boys and 157 (50.2 %) girls. 258 people were tested for the spectrum of depressive disorders, of which 51.9 % (134) were boys and 48.1 % (124) girls. Spielberger State-Trait Anxiety Inventory (STAI) was used to study anxiety, and Children's Depression Inventory (CDI) by M. Kovacs, was used to diagnose depression. The probability was evaluated using Student's t-test with the construction of a 95 % confidence interval (CI) for the difference in means. Quantitative traits are given as M±σ. A high level of personal anxiety was determined in 20 (6.4 %), and situational anxiety in 17 (5.4 %) people. The average level of personal anxiety was determined in 38 (12.1 %), and situational anxiety – in 142 (45.3 %) people. A low level of personal anxiety was identified in 255 (81.5 %), and situational anxiety – in 154 (49.3 %) people. That is, most students of early adolescence had a low level of both personal and situational anxiety. Signs of depressive disorders were detected in 50.0 % of the examined children of early adolescence who completed the questionnaires, in particular, mild manifestations of depression were found in 70 (27.2 %) people, moderate in 46 (17.2 %) people, severe depression in 13 (5.0 %) people. The level of depressive symptoms in girls was higher (53.32±12.54 points) compared with boys (50.01±9.94 points), respectively (95 % CI, 0.5 – 6.0; p<0.019). The level of depressive symptoms among students in the city was higher (50.45±8.93 points) compared with students in rural schools (46.74±10.81 points), respectively (95% CI, 0.5 – 6.9, p<0.023). When comparing the severity of depressive symptoms in children from a boarding school (59.64±15.03 points) with students of other secondary schools (52.02±9.74 points), its predominance was significant precisely in children who study at a boarding school (95% CI, 2.5 – 16.3; p<0.008). So, in children of early adolescence, most have a low level of anxiety. At the same time, depressive disorders of varying degrees were revealed in 50.0 % of the examined children, which manifested themselves mainly in the form of low mood and anhedonia. Female sex, urban living, and having an incomplete family or orphanhood are some of the key risk factors for depression in young children.

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The role of some additional risk factors in the occurrence of paroxysmal / persistent atrial fibrillation in patients with arterial hypertension

European Journal of Preventive Cardiology ◽

10.1093/eurjpc/zwab061 ◽

2021 ◽

Vol 28 (Supplement_1) ◽

Author(s):

S Grigoryan ◽

LG Hazarapetyan ◽

AA Ter-Markaryan ◽

AA Stepanyan

Keyword(s):

Risk Factors ◽

Atrial Fibrillation ◽

Arterial Hypertension ◽

Diastolic Pressure ◽

Control Group ◽

Additional Risk ◽

Hypertensive Patients ◽

Markers Of Inflammation ◽

Hypertensive Crises ◽

Tgf Β1

Abstract Funding Acknowledgements Type of funding sources: None. Background Arterial hypertension (AH) and atrial fibrillation (AF) are two important public health problems and often coexist in the same patient. AH ultimately increases the risk of AF and several pathogenetic mechanisms underlying the higher risk of AF in hypertensive patients are still incompletely known. AH is one of the main reasons for the remodeling process in these patients and makes a significant contribution to the development of structural changes. The aim of this study is to identify predictors of paroxysmal/persistent AF occurrence and progression in hypertensive patients Methods In this study where enrolled 109 hypertensive patients with non-valvular paroxysmal/persistent AF (mean age 61.6 ±6.4) who were hospitalized at Institute of Cardiology between 2008 and 2016 year. As a control group, 44 hypertensive patients without AF were also examined. The study lasted 8 years. After the enrollment the echocardiography examination and 24-hour ambulatory Holter monitoring ECG were registered in each patient. We measured plasma indexes of inflammation (hsCRP, IL-6) and fibrosis marker - transforming growth factor (TGF-β1). The database consisting of 33 indicators that characterize the clinical, hemodynamic and structural-functional state of the heart, as well as markers of inflammation and fibrosis was created. .All data were analyzed by SPSS 13 and EXCEL - 2013 programs using logistic analysis by odds ratio (OR). Results The comparative results of clinical, hemodynamic, inflammation and fibrosis markers OR with AF in hypertensive patients relative to the control group showed that in hypertensive patients with AF there was a significant increase in diastolic pressure (OR 1.09, р=0.017) , the number of hypertensive crises episodes ( OR 1.56 р=0.001) and patients of older age groups (OR 1.18, р= 0.001) There was a significant deterioration in electrical remodeling (Pmax 3.92, р=0.001, P dispersion 4.90, р=0.001), LV diastolic function (isometric ventricular contraction time 1.69, р=0.042) and of left atrial volume (OR 3.69, р=0.001). There were significant increases in levels of inflammatory and fibrosis markers concentrations in comported with hypertensive patients without AF (OR of hsСRP 5.57, р=0.01; IL-6 4.80, р=0.001 and TGF-β1 3.84, р=0.005). Conclusions The multifactorial analysis revealed that increased diastolic pressure, frequency of hypertensive crises, age, deterioration of diastolic function, as well as an increase in markers of inflammation and fibrosis concentration are additional risk factors for AF in patients with hypertension.

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The role of risk factors and endothelium dysfunction in the pathogenesis of the high normal arterial preassure and clinical signs of the vegetative disturbances in children

Systemic Hypertension ◽

10.26442/sg29100 ◽

2015 ◽

Vol 12 (4) ◽

pp. 6-10

Author(s):

N A Maksimovich

Keyword(s):

Risk Factors ◽

Arterial Pressure ◽

Arterial Hypertension ◽

High Frequency ◽

Clinical Signs ◽

Normal Pressure ◽

Early Diagnostics ◽

Endothelium Dysfunction ◽

High Level

As a result of investigation of the children the dysfunction of endothelium at high normal arterial pressure is the cause of the hemodynamic disturbances of children, equal of the arterial hypertension. As a result the children with high normal arterial pressure are the groups of the risk for arterial hypertension wich need the complex of correction of theses disturbances, early diagnostics of the arterial hypertension and its profylaxis. AT high level risk factors and vasoconstrictive properties at children with high normal arterial pressure the more high frequency of headache, the heart pain, both pains and the episodes of high normal pressure.

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The results of the risk factors study for the development of cerebrovascular diseases in women in Kyiv city

HEALTH OF WOMAN ◽

10.15574/hw.2020.151-152.54 ◽

2020 ◽

pp. 54-57

Author(s):

G.О. Slabkiy ◽

◽

М.М. Prokopiv ◽

Keyword(s):

Risk Factors ◽

Cerebrovascular Disease ◽

Healthy Lifestyle ◽

Cerebrovascular Diseases ◽

Cerebral Stroke ◽

Hypertensive Disease ◽

Working Age ◽

Hereditary Nature ◽

High Level ◽

The Impact

Cerebrovascular diseases in the leading countries of the world occupy the second place among all the causes of death and become the main cause of disability of the population in working age. Preventive measures for the development of cerebrovascular disease are directed at eliminating or reducing the impact of risk factors of disease. The objective: to define risk factors for the development of cerebrovascular disease in women under the age of 40 years residing in Kyiv. Materials and methods. 420 women under the age of 40 years residing in Kyiv were questioned with the use of sociological method. A universal adapted questionnaire was used to conduct the research. The results were processed with the application of statistical method and the method of structural-and-logical analysis. Results. It has been defined that up to 32.0% of women have risk factors for developing cerebrovascular diseases of medical nature, up to 69.0% – of hereditary nature, up to 69.0% – of those associated with lifestyle and 32.0% – of socio-economic nature. Among women who did not have a diagnosis of cerebrovascular disease 24.6±2.2% of the polled have hypertensive disease. At the same time, 21.9±2.1% of them do not follow the doctor’s recommendations on healthy lifestyle and 13.8±1.7% of them do not follow the recommendations of the doctor on taking medications. Among women who have been diagnosed with cerebrovascular disease 31.7±2.3% of the polled have hypertensive disease. At the same time, 48.7±2.5% of them do not follow the doctor’s recommendations on healthy lifestyle and 38.5±2.4% do not follow the recommendations of the doctor regarding the intake of medicines. All that leads to high risks of developing a cerebral stroke. Conclusions. A high level of risk factors for cerebrovascular disease was defined among women aged up to 40 years of life residing in Kyiv that requires the introduction of comprehensive information and sanitary preventive programs. Keywords: Kyiv, women, cerebrovascular diseases, risk factors.

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Association of rs10507391 polymorphism with the development of acute cerebrovascular event

European Heart Journal ◽

10.1093/eurheartj/ehab724.2051 ◽

2021 ◽

Vol 42 (Supplement_1) ◽

Author(s):

A Chernova ◽

S Nikulina ◽

D Nikulin

Keyword(s):

Risk Factors ◽

Arterial Hypertension ◽

Genetic Research ◽

Statistical Processing ◽

Main Group ◽

Control Group ◽

Cerebrovascular Event ◽

Cardiovascular Pathology ◽

Arterial Blood ◽

Increased Risk

Abstract Purpose To study SNP rs10507391 association (A> T) with development of Acute Cerebrovascular Event in the patients with cardiovascular pathology and risk factors of its development who are representatives of the east Siberian population. Material and methods 260 patients with Acute Cerebrovascular Event participated in a research (age [57.0; 51.0–62.0]) and 272 patients of control group (age [55.0; 51.0–62.0].). Among the patients who transferred Acute Cerebrovascular Event, 157 men and 103 women. The control group included 170 men and 102 women. Inspection of the main group included: collecting complaints, anamnesis, clinical examination, computer tomography of a brain, electrocardiography, echo, ultrasonic of arteries, daily monitoring of arterial blood pressure and cardiac rhythm, analysis of a coagulant system of blood. Patients of the main group had the following cardiovascular pathology and risk factors: arterial hypertension, supraventricular tachycardia, dislipidemiya, atherosclerosis brachiocephalic of arteries, disturbances of a system of a hemostasis. The control group is examined within the international HAPIEE project. The molecular and genetic research was conducted by PCR method in real time. Statistical processing of material was carried out with use of set of the Statistica for Windows 7.0, Excel and SPSS 22 application programs. Results When studying SNP rs10507391 association (A> T) connection between a rare genotype of a TT and an allele of T and the increased risk of Acute Cerebrovascular Event is established with development of Acute Cerebrovascular Event in all analyzed groups and subgroups of patients. Conclusion A genotype of a TT and an allele of T of SNP rs10507391 (A> T) increases risk of development of an acute disorder of cerebral circulation in patients regardless of the previous cardiovascular pathology and risk factors, including at patients with arterial hypertension, supraventricular tachyarrhythmias, atherosclerosis the brachiocephalic of arteries, disturbance of lipidic exchange and the system of a hemostasis. FUNDunding Acknowledgement Type of funding sources: None.

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Heart rate variability in pregnant women with arterial hypertension

Arterial’naya Gipertenziya (Arterial Hypertension) ◽

10.18705/1607-419x-2011-17-4-366-371 ◽

2011 ◽

Vol 17 (4) ◽

pp. 366-371

Author(s):

L. L. Alexeeva ◽

N. V. Protopopova ◽

I. B. Fatkullina

Keyword(s):

Heart Rate ◽

Heart Rate Variability ◽

Arterial Hypertension ◽

Pregnant Women ◽

Heart Rhythm ◽

First Trimester ◽

Russian Population ◽

Control Group ◽

Heart Rhythm Variability ◽

Sympathetic Regulation

Objective. To study heart rhythm variability (HRV) in ethnic groups of pregnant women with and without arterial hypertension during all gestation period. Design and methods. 100 pregnant Russian and Buryat women with arterial hypertension formed the main group. The control group included 100 healthy pregnant women with a normal current of pregnancy, without arterial hypertensions. All subjects underwent Holter ECG monitoring («Incart», «Kardiotechnika-04-BP-3», Russia). Results. There is a significant decrease in time parameters of rhythm variability n pregnant Buryat women with arterial hypertension in the second trimester. In the third trimester of pregnancy heart rhythm variability is higher in hypertensive women compared to those without hypertension. In Russian population indicators of heart rate variability do not vary during the day. In an ethnic group of women with arterial hypertension an increase of indicators of low and high frequencies due to the prevalence of vascular sympathetic regulation is observed in the first trimester of pregnancy. Conclusions. Pregnant women of the Buryat population with arterial hypertension have lower heart rhythm variability in the first and second trimesters of pregnancy. In Russian population the variability parameters do not change.

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